1XM1
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![BU of 1xm1 by Molmil](/molmil-images/mine/1xm1) | Nonbasic Thrombin Inhibitor Complex | 分子名称: | Hirudin, N-{[(2S)-1-(N-{[4-({[AMINO(IMINO)METHYL]AMINO}METHYL)CYCLOHEXYL]CARBONYL}-3-CYCLOHEXYL-L-ALANYL)AZETIDIN-2-YL]CARBONYL}-L-TYROSYL-N~6~-[AMINO(IMINO)METHYL]-L-LYSINAMIDE, thrombin | 著者 | Friedrich, R, Bode, W, Schwienhorst, A. | 登録日 | 2004-10-01 | 公開日 | 2005-05-10 | 最終更新日 | 2013-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Nonbasic Thrombin Inhibitor Complex To be Published
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2A1D
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![BU of 2a1d by Molmil](/molmil-images/mine/2a1d) | Staphylocoagulase bound to bovine thrombin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, SODIUM ION, ... | 著者 | Friedrich, R, Panizzi, P, Kawabata, S, Bode, W, Bock, P.E, Fuentes-Prior, P. | 登録日 | 2005-06-20 | 公開日 | 2005-09-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural Basis for Reduced Staphylocoagulase-mediated Bovine Prothrombin Activation J.Biol.Chem., 281, 2006
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1EAX
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![BU of 1eax by Molmil](/molmil-images/mine/1eax) | Crystal structure of MTSP1 (matriptase) | 分子名称: | BENZAMIDINE, SULFATE ION, SUPPRESSOR OF TUMORIGENICITY 14 | 著者 | Friedrich, R, Bode, W. | 登録日 | 2001-07-17 | 公開日 | 2002-01-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Catalytic Domain Structures of Mt-Sp1/Matriptase, a Matrix-Degrading Transmembrane Serine Proteinase. J.Biol.Chem., 277, 2002
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1EAW
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![BU of 1eaw by Molmil](/molmil-images/mine/1eaw) | |
1EB1
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![BU of 1eb1 by Molmil](/molmil-images/mine/1eb1) | Complex structure of human thrombin with N-methyl-arginine inhibitor | 分子名称: | 3-CYCLOHEXYL-D-ALANYL-L-PROLYL-N~2~-METHYL-L-ARGININE, PEPTIDE INHIBITOR, THROMBIN HEAVY CHAIN, ... | 著者 | Friedrich, R, Steinmetzer, T, Bode, W. | 登録日 | 2001-07-18 | 公開日 | 2002-01-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Methyl Group of N(Alpha)(Me)Arg-Containing Peptides Disturbs the Active-Site Geometry of Thrombin, Impairing Efficient Cleavage J.Mol.Biol., 316, 2002
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1NU9
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![BU of 1nu9 by Molmil](/molmil-images/mine/1nu9) | Staphylocoagulase-Prethrombin-2 complex | 分子名称: | IMIDAZOLE, MERCURY (II) ION, N-(sulfanylacetyl)-D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | 著者 | Friedrich, R, Bode, W, Fuentes-Prior, P, Panizzi, P, Bock, P.E. | 登録日 | 2003-01-31 | 公開日 | 2003-10-07 | 最終更新日 | 2012-12-12 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation NATURE, 425, 2003
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1NU7
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![BU of 1nu7 by Molmil](/molmil-images/mine/1nu7) | Staphylocoagulase-Thrombin Complex | 分子名称: | IMIDAZOLE, MERCURY (II) ION, N-(sulfanylacetyl)-D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, ... | 著者 | Friedrich, R, Bode, W, Fuentes-Prior, P, Panizzi, P, Bock, P.E. | 登録日 | 2003-01-31 | 公開日 | 2003-10-07 | 最終更新日 | 2012-12-12 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation NATURE, 425, 2003
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2AKP
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![BU of 2akp by Molmil](/molmil-images/mine/2akp) | Hsp90 Delta24-N210 mutant | 分子名称: | ATP-dependent molecular chaperone HSP82 | 著者 | Richter, K, Moser, S, Hagn, F, Friedrich, R, Hainzl, O, Heller, M, Schlee, S, Kessler, H, Reinstein, J, Buchner, J. | 登録日 | 2005-08-03 | 公開日 | 2006-01-31 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Intrinsic inhibition of the Hsp90 ATPase activity. J.Biol.Chem., 281, 2006
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2BDI
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![BU of 2bdi by Molmil](/molmil-images/mine/2bdi) | Human Kallikrein 4 complex with cobalt and p-aminobenzamidine | 分子名称: | COBALT (II) ION, Kallikrein-4, P-AMINO BENZAMIDINE | 著者 | Debela, M, Bode, W, Goettig, P, Structural Proteomics in Europe (SPINE) | 登録日 | 2005-10-20 | 公開日 | 2006-10-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site. J.Mol.Biol., 362, 2006
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2BDH
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![BU of 2bdh by Molmil](/molmil-images/mine/2bdh) | Human Kallikrein 4 complex with zinc and p-aminobenzamidine | 分子名称: | Kallikrein-4, P-AMINO BENZAMIDINE, ZINC ION | 著者 | Debela, M, Bode, W, Goettig, P, Structural Proteomics in Europe (SPINE) | 登録日 | 2005-10-20 | 公開日 | 2006-10-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site. J.Mol.Biol., 362, 2006
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2BDG
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![BU of 2bdg by Molmil](/molmil-images/mine/2bdg) | Human Kallikrein 4 complex with nickel and p-aminobenzamidine | 分子名称: | CHLORIDE ION, Kallikrein-4, NICKEL (II) ION, ... | 著者 | Debela, M, Bode, W, Goettig, P, Structural Proteomics in Europe (SPINE) | 登録日 | 2005-10-20 | 公開日 | 2006-10-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structures of human tissue kallikrein 4: activity modulation by a specific zinc binding site. J.Mol.Biol., 362, 2006
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2GV7
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![BU of 2gv7 by Molmil](/molmil-images/mine/2gv7) | Structure of Matriptase in Complex with Inhibitor CJ-672 | 分子名称: | (S)-4-(4-(3-(3-CARBAMIMIDOYLPHENYL)-2-(2,4,6-TRIISOPROPYLPHENYLSULFONAMIDO)PROPANOYL)PIPERAZINE-1-CARBONYL)PIPERIDINE-1-CARBOXIMIDAMIDE, Suppressor of tumorigenicity 14 | 著者 | Bode, W. | 登録日 | 2006-05-02 | 公開日 | 2006-06-06 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Secondary Amides of Sulfonylated 3-Amidinophenylalanine. New Potent and Selective Inhibitors of Matriptase. J.Med.Chem., 49, 2006
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2GV6
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![BU of 2gv6 by Molmil](/molmil-images/mine/2gv6) | Crystal Structure of Matriptase with Inhibitor CJ-730 | 分子名称: | (S)-3-(3-(4-(2-GUANIDINOETHYL)PIPERIDIN-1-YL)-2-(NAPHTHALENE-2-SULFONAMIDO)-3-OXOPROPYL)BENZIMIDAMIDE, Suppressor of tumorigenicity 14 | 著者 | Bode, W. | 登録日 | 2006-05-02 | 公開日 | 2006-06-06 | 最終更新日 | 2021-06-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Secondary Amides of Sulfonylated 3-Amidinophenylalanine. New Potent and Selective Inhibitors of Matriptase. J.Med.Chem., 49, 2006
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