1NJQ
| NMR structure of the single QALGGH zinc finger domain from Arabidopsis thaliana SUPERMAN protein | 分子名称: | ZINC ION, superman protein | 著者 | Isernia, C, Bucci, E, Leone, M, Zaccaro, L, Di Lello, P, Digilio, G, Esposito, S, Saviano, M, Di Blasio, B, Pedone, C, Pedone, P.V, Fattorusso, R. | 登録日 | 2003-01-02 | 公開日 | 2003-03-04 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of the Single QALGGH Zinc Finger Domain from the Arabidopsis thaliana SUPERMAN Protein. Chembiochem, 4, 2003
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2L1O
| Zinc to cadmium replacement in the A. thaliana SUPERMAN Cys2His2 zinc finger induces structural rearrangements of typical DNA base determinant positions | 分子名称: | CADMIUM ION, Transcriptional regulator SUPERMAN | 著者 | Malgieri, G, Zaccaro, L, Leone, M, Bucci, E, Esposito, S, Baglivo, I, Del Gatto, A, Scandurra, R, Pedone, P.V, Fattorusso, R, Isernia, C. | 登録日 | 2010-07-31 | 公開日 | 2011-06-08 | 最終更新日 | 2011-12-21 | 実験手法 | SOLUTION NMR | 主引用文献 | Zinc to cadmium replacement in the A. thaliana SUPERMAN Cys(2) His(2) zinc finger induces structural rearrangements of typical DNA base determinant positions. Biopolymers, 95, 2011
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8CBH
| SHP2 in complex with a novel allosteric inhibitor | 分子名称: | Tyrosine-protein phosphatase non-receptor type 11, [(1~{S},6~{R},7~{S})-3-[3-[2,3-bis(chloranyl)phenyl]-2~{H}-pyrazolo[3,4-b]pyrazin-6-yl]-7-(4-methyl-1,3-thiazol-2-yl)-3-azabicyclo[4.1.0]heptan-7-yl]methanamine | 著者 | di Fabio, R, Petrocchi, A. | 登録日 | 2023-01-25 | 公開日 | 2023-04-26 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Discovery of a Novel Series of Imidazopyrazine Derivatives as Potent SHP2 Allosteric Inhibitors. Acs Med.Chem.Lett., 14, 2023
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8B5Y
| SHP2 in complex with allosteric imidazopyrazine inhibitor | 分子名称: | (1~{S})-1'-[5-[2-(trifluoromethyl)pyridin-3-yl]sulfanyl-3~{H}-imidazo[4,5-b]pyrazin-2-yl]spiro[1,3-dihydroindene-2,4'-piperidine]-1-amine, FORMIC ACID, Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Torrente, E, Petrocchi, A. | 登録日 | 2022-09-25 | 公開日 | 2023-01-18 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Discovery of a Novel Series of Imidazopyrazine Derivatives as Potent SHP2 Allosteric Inhibitors. Acs Med.Chem.Lett., 14, 2023
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2JSP
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