4YXY
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4YXX
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4YXZ
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5BYO
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6MGB
| Thermosulfurimonas dismutans KpsC, beta Kdo 2,4 transferase | 分子名称: | CHLORIDE ION, CYTIDINE-5'-MONOPHOSPHATE, Capsular polysaccharide export system protein KpsC, ... | 著者 | Doyle, L, Mallette, E, Kimber, M.S, Whitfield, C. | 登録日 | 2018-09-13 | 公開日 | 2019-03-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules. Nat.Chem.Biol., 15, 2019
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6MGC
| Escherichia coli KpsC, N-terminal domain | 分子名称: | CHLORIDE ION, CYTIDINE-5'-MONOPHOSPHATE, Capsule polysaccharide export protein KpsC, ... | 著者 | Doyle, L, Mallette, E, Kimber, M.S. | 登録日 | 2018-09-13 | 公開日 | 2019-03-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules. Nat.Chem.Biol., 15, 2019
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6MGD
| Thermosulfurimonas dismutans KpsC, beta Kdo 2,7 transferase | 分子名称: | Capsular polysaccharide export system protein KpsC | 著者 | Doyle, L, Mallette, E, Kimber, M.S, Whitfield, C. | 登録日 | 2018-09-13 | 公開日 | 2019-03-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules. Nat.Chem.Biol., 15, 2019
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8FUX
| KpsC D160C ternary complex | 分子名称: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, 3-deoxy-beta-D-manno-oct-2-ulopyranosonic acid, CHLORIDE ION, ... | 著者 | Kimber, M.S, Doyle, L, Whitfield, C. | 登録日 | 2023-01-18 | 公開日 | 2023-03-08 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Mechanism and linkage specificities of the dual retaining beta-Kdo glycosyltransferase modules of KpsC from bacterial capsule biosynthesis. J.Biol.Chem., 299, 2023
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8FUW
| KpsC D160N Kdo adduct | 分子名称: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, CHLORIDE ION, CYTIDINE-5'-MONOPHOSPHATE, ... | 著者 | Kimber, M.S, Doyle, L, Whitfield, C. | 登録日 | 2023-01-18 | 公開日 | 2023-03-08 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanism and linkage specificities of the dual retaining beta-Kdo glycosyltransferase modules of KpsC from bacterial capsule biosynthesis. J.Biol.Chem., 299, 2023
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5CW9
| Crystal structure of De novo designed ferredoxin-ferredoxin domain insertion protein | 分子名称: | De novo designed ferredoxin-ferredoxin domain insertion protein | 著者 | DiMaio, F, King, I.C, Gleixner, J, Doyle, L, Stoddard, B, Baker, D. | 登録日 | 2015-07-28 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.108 Å) | 主引用文献 | Precise assembly of complex beta sheet topologies from de novo designed building blocks. Elife, 4, 2015
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4YY2
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4YY5
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7T8K
| BrxR from Acinetobacter BREX type I phage restriction system bound to DNA | 分子名称: | 1,2-ETHANEDIOL, BrxR, CHLORIDE ION, ... | 著者 | Doyle, L, Kaiser, B, Stoddard, B. | 登録日 | 2021-12-16 | 公開日 | 2022-05-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system. Nucleic Acids Res., 50, 2022
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7T8L
| BrxR from Acinetobacter BREX type I phage restriction system | 分子名称: | 1,2-ETHANEDIOL, BrxR, CHLORIDE ION | 著者 | Doyle, L, Kaiser, B, Stoddard, B. | 登録日 | 2021-12-16 | 公開日 | 2022-05-18 | 最終更新日 | 2022-06-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system. Nucleic Acids Res., 50, 2022
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3B5L
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3HOJ
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5D9K
| Rsk2 N-terminal Kinase in Complex with BI-D1870 | 分子名称: | (7R)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5H)-one, GLYCEROL, Ribosomal protein S6 kinase alpha-3 | 著者 | Appleton, B.A. | 登録日 | 2015-08-18 | 公開日 | 2015-09-02 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Discovery of Potent and Selective RSK Inhibitors as Biological Probes. J.Med.Chem., 58, 2015
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5D9L
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4J8T
| Engineered Digoxigenin binder DIG10.2 | 分子名称: | DIGOXIGENIN, Engineered Digoxigenin binder protein DIG10.2 | 著者 | Stoddard, B.L, Doyle, L.A. | 登録日 | 2013-02-14 | 公開日 | 2013-06-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Computational design of ligand-binding proteins with high affinity and selectivity. Nature, 501, 2013
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4J9A
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5IEO
| Structure of CDL2.3a, a computationally designed Vitamin-D3 binder | 分子名称: | 1,2-ETHANEDIOL, 3-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANOL, CDL2.3a | 著者 | Stoddard, B.L, Doyle, L.A. | 登録日 | 2016-02-25 | 公開日 | 2017-03-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | 主引用文献 | Unintended specificity of an engineered ligand-binding protein facilitated by unpredicted plasticity of the protein fold. Protein Eng.Des.Sel., 31, 2018
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5IER
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5IEP
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5IF6
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5IEN
| Structure of CDL2.2, a computationally designed Vitamin-D3 binder | 分子名称: | 3-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANOL, CDL2.2, GLYCEROL | 著者 | Stoddard, B.L, Doyle, L.A. | 登録日 | 2016-02-25 | 公開日 | 2017-03-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.089 Å) | 主引用文献 | Unintended specificity of an engineered ligand-binding protein facilitated by unpredicted plasticity of the protein fold. Protein Eng.Des.Sel., 31, 2018
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