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6KR5
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Crystal structure of O-Acetyl Serine Sulfhydrylase isoform 3 from Entamoeba histolytica
分子名称: Cysteine synthase 3, PYRIDOXAL-5'-PHOSPHATE
著者Dharavath, S, Gourinath, S.
登録日2019-08-21
公開日2020-09-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.544 Å)
主引用文献Crystal structure of O-Acetylserine sulfhydralase (OASS) isoform 3 from Entamoeba histolytica: Pharmacophore-based virtual screening and validation of novel inhibitors.
Eur.J.Med.Chem., 192, 2020
7BW9
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BU of 7bw9 by Molmil
Crystal structure of Serine acetyltransferase isoform 3 in complex with cysteine from Entamoeba histolytica
分子名称: CYSTEINE, Serine acetyltransferase 1, putative
著者Dharavath, S, Kumar, S, Gourinath, S.
登録日2020-04-14
公開日2021-04-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.131 Å)
主引用文献Crystal structure of Serine acetyltransferase isoform 3 in complex with cysteine from Entamoeba histolytica
To Be Published
7R97
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BU of 7r97 by Molmil
Crystal structure of postcleavge complex of Escherichia coli RNase III
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Dharavath, S, Shaw, G.X, Ji, X.
登録日2021-06-28
公開日2022-07-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.804 Å)
主引用文献Structural basis for Dicer-like function of an engineered RNase III variant and insights into the reaction trajectory of two-Mg 2+ -ion catalysis.
Rna Biol., 19, 2022
5JIS
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BU of 5jis by Molmil
The Crystal Structure of O-acetyl serine sulfhydralase from Brucella abortus
分子名称: Cysteine synthase
著者Dharavath, S, Gourinath, S.
登録日2016-04-22
公開日2017-04-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-based mutational studies of O-acetylserine sulfhydrylase reveal the reason for the loss of cysteine synthase complex formation in Brucella abortus
Biochem. J., 474, 2017
5JJC
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BU of 5jjc by Molmil
Crystal Structure of double mutant (Q96A-Y125A) O-Acetyl Serine Sulfhydralase from Brucella abortus
分子名称: Cysteine synthase
著者Dharavath, S, Gourinath, S.
登録日2016-04-23
公開日2017-04-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structure-based mutational studies of O-acetylserine sulfhydrylase reveal the reason for the loss of cysteine synthase complex formation in Brucella abortus
Biochem. J., 474, 2017
5JZX
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BU of 5jzx by Molmil
Crystal Structure of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) from Mycobacterium tuberculosis
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, POTASSIUM ION, UDP-N-acetylenolpyruvoylglucosamine reductase
著者Dharavath, S, Eniyan, K, Bajpai, U, Gourinath, S.
登録日2016-05-17
公開日2017-05-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of UDP-N-acetylglucosamine-enolpyruvate reductase (MurB) from Mycobacterium tuberculosis
Biochim. Biophys. Acta, 1866, 2017
6ADD
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BU of 6add by Molmil
The crystal structure of Rv2747 from Mycobacterium tuberculosis in complex with CoA and NLQ
分子名称: Amino-acid acetyltransferase, COENZYME A, N~2~-ACETYL-L-GLUTAMINE
著者Das, U, Singh, E, Pal, R.K, Tiruttani Subhramanyam, U.K, Gourinath, S, Srinivasan, A.
登録日2018-07-31
公開日2018-12-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structural insights into the substrate binding mechanism of novel ArgA from Mycobacterium tuberculosis
Int. J. Biol. Macromol., 125, 2019
5YO2
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BU of 5yo2 by Molmil
The crystal structure of Rv2747 from Mycobacterium tuberculosis in complex with Acetyl CoA and L-Arginine
分子名称: ACETYL COENZYME *A, ARGININE, Amino-acid acetyltransferase
著者Singh, E, Tiruttani Subhramanyam, U.K, Pal, R.K, Srinivasan, A, Gourinath, S, Das, U.
登録日2017-10-26
公開日2018-11-07
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.997 Å)
主引用文献Structural insights into the substrate binding mechanism of novel ArgA from Mycobacterium tuberculosis
Int. J. Biol. Macromol., 125, 2019
5YB0
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BU of 5yb0 by Molmil
Crystal Structure of Wild Type Phosphoserine aminotransferase (PSAT) from E. histolytica
分子名称: CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, Phosphoserine aminotransferase
著者Singh, R.K, Gourinath, S.
登録日2017-09-02
公開日2018-10-31
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献N-terminal residues are crucial for quaternary structure and active site conformation for the phosphoserine aminotransferase from enteric human parasite E. histolytica.
Int.J.Biol.Macromol., 132, 2019
5YD2
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BU of 5yd2 by Molmil
Crystal Structure of Delta 4 mutant of EhPSAT (Phosphoserine aminotransferase of Entamoeba histolytica)
分子名称: CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, Phosphoserine aminotransferase
著者Singh, R.K, Gourinath, S.
登録日2017-09-10
公開日2018-10-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献N-terminal residues are crucial for quaternary structure and active site conformation for the phosphoserine aminotransferase from enteric human parasite E. histolytica.
Int.J.Biol.Macromol., 132, 2019
5YII
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BU of 5yii by Molmil
Crystal Structure of 45 amino acid deleted from N-terminal of Phosphoserine Aminotransferase (PSAT) of Entamoeba histolytica
分子名称: Phosphoserine aminotransferase, THIOCYANATE ION
著者Singh, R.K, Gourinath, S.
登録日2017-10-04
公開日2018-10-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献N-terminal residues are crucial for quaternary structure and active site conformation for the phosphoserine aminotransferase from enteric human parasite E. histolytica.
Int.J.Biol.Macromol., 132, 2019
3ZHX
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BU of 3zhx by Molmil
Structure of Mycobacterium tuberculosis DXR in complex with a fosmidomycin analogue
分子名称: 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, MANGANESE (II) ION, [(1S)-1-(3,4-dichlorophenyl)-3-[oxidanyl(phenylcarbonyl)amino]propyl]phosphonic acid
著者Bjorkelid, C, Jansson, A.M, Bergfors, T, Unge, T, Mowbray, S.L, Jones, T.A.
登録日2012-12-30
公開日2013-10-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dxr Inhibition by Potent Mono- and Disubstituted Fosmidomycin Analogues.
J.Med.Chem., 56, 2013
3ZI0
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BU of 3zi0 by Molmil
Structure of Mycobacterium tuberculosis DXR in complex with a fosmidomycin analogue
分子名称: 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, MANGANESE (II) ION, [(1S)-1-(3,4-dichlorophenyl)-3-{hydroxy[2-(1H-1,2,4-triazol-1-ylmethyl)benzoyl]amino}propyl]phosphonic acid
著者Bjorkelid, C, Jansson, A.M, Bergfors, T, Unge, T, Mowbray, S.L, Jones, T.A.
登録日2012-12-30
公開日2013-10-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Dxr Inhibition by Potent Mono- and Disubstituted Fosmidomycin Analogues.
J.Med.Chem., 56, 2013
3ZHY
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BU of 3zhy by Molmil
Structure of Mycobacterium tuberculosis DXR in complex with a di- substituted fosmidomycin analogue
分子名称: 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, MANGANESE (II) ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Bjorkelid, C, Jansson, A.M, Bergfors, T, Unge, T, Mowbray, S.L, Jones, T.A.
登録日2012-12-30
公開日2013-10-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Dxr Inhibition by Potent Mono- and Disubstituted Fosmidomycin Analogues.
J.Med.Chem., 56, 2013
3ZHZ
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BU of 3zhz by Molmil
Structure of Mycobacterium tuberculosis DXR in complex with a fosmidomycin analogue
分子名称: 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE, [(1S)-1-(3,4-dichlorophenyl)-3-[oxidanyl-[2-[[3-(trifluoromethyl)phenyl]amino]phenyl]carbonyl-amino]propyl]phosphonic acid
著者Bjorkelid, C, Jansson, A.M, Bergfors, T, Unge, T, Mowbray, S.L, Jones, T.A.
登録日2012-12-30
公開日2013-10-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Dxr Inhibition by Potent Mono- and Disubstituted Fosmidomycin Analogues.
J.Med.Chem., 56, 2013

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件を2024-07-10に公開中

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