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1I2G
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Ribonuclease T1 V16T mutant
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1
著者De Vos, S, Backmann, J, Steyaert, J, Loris, R.
登録日2001-02-09
公開日2001-03-07
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
1I2F
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BU of 1i2f by Molmil
Ribonuclease T1 V16A mutant, form II
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1
著者De Vos, S, Backmann, J, Steyaert, J, Loris, R.
登録日2001-02-09
公開日2001-03-07
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
1I3F
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BU of 1i3f by Molmil
Ribonuclease T1 V89S mutant
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1
著者De Vos, S, Backmann, J, Steyaert, J, Loris, R.
登録日2001-02-15
公開日2001-03-07
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
1I3I
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BU of 1i3i by Molmil
Ribonuclease T1 V78T mutant
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1
著者De Vos, S, Backmann, J, Steyaert, J, Loris, R.
登録日2001-02-15
公開日2001-03-07
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
1FYS
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BU of 1fys by Molmil
Ribonuclease T1 V16C mutant
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1
著者De Vos, S, Loris, R, Steyaert, J.
登録日2000-10-03
公開日2000-10-25
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Hydrophobic core manipulations in ribonuclease T1.
Biochemistry, 40, 2001
1I2E
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BU of 1i2e by Molmil
Ribonuclease T1 V16A mutant, form I
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1
著者De Vos, S, Backmann, J, Steyaert, J, Loris, R.
登録日2001-02-09
公開日2001-03-07
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Hydrophobic core manipulations in ribonuclease T1
Biochemistry, 40, 2001
1FZU
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BU of 1fzu by Molmil
RNAse T1 V78A mutant
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1
著者De Vos, S, Loris, R, Steyaert, J.
登録日2000-10-04
公開日2000-10-25
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Hydrophobic core manipulations in ribonuclease T1.
Biochemistry, 40, 2001
1G02
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BU of 1g02 by Molmil
Ribonuclease T1 V16S mutant
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1
著者De Vos, S, Loris, R, Steyaert, J.
登録日2000-10-05
公開日2000-10-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Hydrophobic core manipulations in ribonuclease T1.
Biochemistry, 40, 2001
3B9G
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Crystal structure of loop deletion mutant of Trypanosoma vivax nucleoside hydrolase (3GTvNH) in complex with ImmH
分子名称: 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, CALCIUM ION, IAG-nucleoside hydrolase, ...
著者Vandemeulebroucke, A, De Vos, S, Van Holsbeke, E, Steyaert, J, Versees, W.
登録日2007-11-05
公開日2008-04-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A Flexible Loop as a Functional Element in the Catalytic Mechanism of Nucleoside Hydrolase from Trypanosoma vivax.
J.Biol.Chem., 283, 2008
1HZ1
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RIBONUCLEASE T1 V16A MUTANT IN COMPLEX WITH MG2+
分子名称: GUANOSINE-2'-MONOPHOSPHATE, MAGNESIUM ION, RIBONUCLEASE T1
著者De Swarte, J, De Vos, S, Langhorst, U, Steyaert, J, Loris, R.
登録日2001-01-23
公開日2001-01-31
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
1I0V
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Ribonuclease T1 in complex with 2'GMP (form I crystal)
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1
著者De Swarte, J, De Vos, S, Langhorst, U, Steyaert, J, Loris, R.
登録日2001-01-30
公開日2001-02-14
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.234 Å)
主引用文献The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
1I0X
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BU of 1i0x by Molmil
RIBONUCLEASE T1 IN COMPLEX WITH 2'GMP (FORM II CRYSTAL)
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1
著者De Swarte, J, De Vos, S, Langhorst, U, Steyaert, J, Loris, R.
登録日2001-01-30
公開日2001-02-14
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
1HYF
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BU of 1hyf by Molmil
RIBONUCLEASE T1 V16A MUTANT IN COMPLEX WITH SR2+
分子名称: GUANOSINE-2'-MONOPHOSPHATE, GUANYL-SPECIFIC RIBONUCLEASE T1, STRONTIUM ION
著者De Swarte, J, De Vos, S, Langhorst, U, Steyaert, J, Loris, R.
登録日2001-01-19
公開日2001-02-14
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The contribution of metal ions to the conformational stability of ribonuclease T1: crystal versus solution.
Eur.J.Biochem., 268, 2001
3BIR
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BU of 3bir by Molmil
DISECTING HISTIDINE INTERACTIONS IN RIBONUCLEASE T1 BY ASN AND GLN SUBSTITUTIONS
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1
著者Doumen, J, Steyaert, J.
登録日1997-06-27
公開日1997-12-31
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dissecting histidine interactions of ribonuclease T1 with asparagine and glutamine replacements: analysis of double mutant cycles at one position.
J.Mol.Biol., 275, 1998
5BIR
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BU of 5bir by Molmil
DISECTING HISTIDINE INTERACTIONS IN RIBONUCLEASE T1 USING ASN AND GLN MUTATIONS
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1
著者Doumen, J, Steyaert, J.
登録日1997-06-30
公開日1997-12-31
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dissecting histidine interactions of ribonuclease T1 with asparagine and glutamine replacements: analysis of double mutant cycles at one position.
J.Mol.Biol., 275, 1998
2BU4
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BU of 2bu4 by Molmil
RIBONUCLEASE T1 COMPLEX WITH 2'GMP
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1)
著者Loris, R, Devos, S, Langhorst, U, Decanniere, K, Bouckaert, J, Maes, D, Transue, T.R, Steyaert, J.
登録日1998-09-14
公開日1998-09-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Conserved water molecules in a large family of microbial ribonucleases.
Proteins, 36, 1999
3BU4
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BU of 3bu4 by Molmil
RIBONUCLEASE T1 COMPLEX WITH 2'GMP
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1)
著者Loris, R, Devos, S, Langhorst, U, Decanniere, K, Bouckaert, J, Maes, D, Transue, T.R, Steyaert, J.
登録日1998-09-14
公開日1998-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Conserved water molecules in a large family of microbial ribonucleases.
Proteins, 36, 1999
1BU4
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BU of 1bu4 by Molmil
RIBONUCLEASE 1 COMPLEX WITH 2'GMP
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE T1
著者Loris, R, Devos, S, Langhorst, U, Decanniere, K, Bouckaert, J, Maes, D, Transue, T.R, Steyaert, J.
登録日1998-09-11
公開日1999-02-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Conserved water molecules in a large family of microbial ribonucleases.
Proteins, 36, 1999
5BU4
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BU of 5bu4 by Molmil
RIBONUCLEASE T1 COMPLEX WITH 2'GMP
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1)
著者Loris, R, Devos, S, Langhorst, U, Decanniere, K, Bouckaert, J, Maes, D, Transue, T.R, Steyaert, J.
登録日1998-09-15
公開日1998-09-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Conserved water molecules in a large family of microbial ribonucleases.
Proteins, 36, 1999
4BU4
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BU of 4bu4 by Molmil
RIBONUCLEASE T1 COMPLEX WITH 2'GMP
分子名称: CALCIUM ION, GUANOSINE-2'-MONOPHOSPHATE, PROTEIN (RIBONUCLEASE T1)
著者Loris, R, Devos, S, Langhorst, U, Decanniere, K, Bouckaert, J, Maes, D, Transue, T.R, Steyaert, J.
登録日1998-09-14
公開日1998-09-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Conserved water molecules in a large family of microbial ribonucleases.
Proteins, 36, 1999
8OKU
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BU of 8oku by Molmil
Salt-Inducible Kinase 3 in complex with an inhibitor
分子名称: Serine/threonine-protein kinase SIK3, ~{N}-ethyl-4-[5-[1-(2-hydroxyethyl)pyrazol-4-yl]benzimidazol-1-yl]-2,6-dimethoxy-benzamide
著者Flower, T.G, Leonard, P.M, Lamers, M.B.A.C, Mollat, P.
登録日2023-03-29
公開日2024-01-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Optimization of Selectivity and Pharmacokinetic Properties of Salt-Inducible Kinase Inhibitors that Led to the Discovery of Pan-SIK Inhibitor GLPG3312.
J.Med.Chem., 67, 2024

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