7SQI
 
 | | Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and C14-crypto Acyl Carrier Protein, AcpP | | 分子名称: | Acyl carrier protein, Beta-ketoacyl-ACP synthase I, N-{2-[(2Z)-3-chlorotetradec-2-enamido]ethyl}-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, ... | | 著者 | Chen, A, Mindrebo, J.T, Davis, T.D, Noel, J.P, Burkart, M.D. | | 登録日 | 2021-11-05 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mechanism-based cross-linking probes capture the Escherichia coli ketosynthase FabB in conformationally distinct catalytic states.
Acta Crystallogr D Struct Biol, 78, 2022
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8DLE
 | | Crosslinked Crystal Structure of the 8-amino-7-oxonanoate synthase, BioF, and Benzene Sulfonyl Fluoride-crypto Acyl Carrier Protein, BSF-ACP | | 分子名称: | 1,2-ETHANEDIOL, 8-amino-7-oxononanoate synthase, Acyl carrier protein, ... | | 著者 | Chen, A, Davis, T.D, Louie, G.V, Bowman, M.E, Noel, J.P, Burkart, M.D. | | 登録日 | 2022-07-07 | | 公開日 | 2023-07-12 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Visualizing the Interface of Biotin and Fatty Acid Biosynthesis through SuFEx Probes.
J.Am.Chem.Soc., 146, 2024
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5JJF
 | | Structure of the SRII/HtrII Complex in I212121 space group ("U" shape) - M state | | 分子名称: | EICOSANE, RETINAL, Sensory rhodopsin II transducer, ... | | 著者 | Ishchenko, A, Round, E, Borshchevskiy, V, Grudinin, S, Gushchin, I, Klare, J, Remeeva, A, Polovinkin, V, Utrobin, P, Balandin, T, Engelhard, M, Bueldt, G, Gordeliy, V. | | 登録日 | 2016-04-23 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex.
Sci Rep, 7, 2017
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5JJE
 | | Structure of the SRII/HtrII Complex in I212121 space group ("U" shape) | | 分子名称: | EICOSANE, RETINAL, Sensory rhodopsin II transducer, ... | | 著者 | Ishchenko, A, Round, E, Borshchevskiy, V, Grudinin, S, Gushchin, I, Klare, J, Remeeva, A, Polovinkin, V, Utrobin, P, Balandin, T, Engelhard, M, Bueldt, G, Gordeliy, V. | | 登録日 | 2016-04-23 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex.
Sci Rep, 7, 2017
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5JJN
 | | Structure of the SRII/HtrII(G83F) Complex in P212121 space group ("V" shape) | | 分子名称: | EICOSANE, RETINAL, Sensory rhodopsin II transducer, ... | | 著者 | Ishchenko, A, Round, E, Borshchevskiy, V, Grudinin, S, Gushchin, I, Klare, J, Remeeva, A, Polovinkin, V, Utrobin, P, Balandin, T, Engelhard, M, Bueldt, G, Gordeliy, V. | | 登録日 | 2016-04-24 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex.
Sci Rep, 7, 2017
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7OMO
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7OMR
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7OME
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7OMD
 | | Crystal structure of azacoelenterazine-bound Renilla reniformis luciferase variant RLuc8-D162A | | 分子名称: | 6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-8-(phenylmethyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one, CHLORIDE ION, Coelenterazine h 2-monooxygenase, ... | | 著者 | Schenkmayerova, A, Janin, Y.L, Marek, M. | | 登録日 | 2021-05-21 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | Catalytic mechanism for Renilla-type luciferases
Nat Catal, 2023
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5VN7
 | | Structure of bacteriorhodopsin from crystals grown at 20 deg Celcius using GlyNCOC15+4 as an LCP host lipid | | 分子名称: | Bacteriorhodopsin | | 著者 | Ishchenko, A, Peng, L, Zinovev, E, Vlasov, A, Lee, S.C, Kuklin, A, Mishin, A, Borshchevskiy, V, Zhang, Q, Cherezov, V. | | 登録日 | 2017-04-28 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Chemically Stable Lipids for Membrane Protein Crystallization.
Cryst Growth Des, 17, 2017
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5VN9
 | | Structure of bacteriorhodopsin from crystals grown at 4 deg C using GlyNCOC15+4 as an LCP host lipid | | 分子名称: | Bacteriorhodopsin | | 著者 | Ishchenko, A, Peng, L, Zinovev, E, Vlasov, A, Lee, S.C, Kuklin, A, Mishin, A, Borshchevskiy, V, Zhang, Q, Cherezov, V. | | 登録日 | 2017-04-28 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.594 Å) | | 主引用文献 | Chemically Stable Lipids for Membrane Protein Crystallization.
Cryst Growth Des, 17, 2017
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2JTV
 | | Solution Structure of protein RPA3401, Northeast Structural Genomics Consortium Target RpT7, Ontario Center for Structural Proteomics Target RP3384 | | 分子名称: | Protein of Unknown Function | | 著者 | Ignatchenko, A, Gutmanas, A, Lemak, A, Yee, A, Karra, M, Srisailam, S, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2007-08-07 | | 公開日 | 2007-10-09 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of protein RPA3401, Northeast Structural Genomics Consortium Target RpT7, Ontario Center for Structural Proteomics Target RP3384
TO BE PUBLISHED
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1P9Q
 | | Structure of a hypothetical protein AF0491 from Archaeoglobus fulgidus | | 分子名称: | Hypothetical protein AF0491 | | 著者 | Savchenko, A, Evdokimova, E, Skarina, T, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A. | | 登録日 | 2003-05-12 | | 公開日 | 2004-06-08 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism.
J.Biol.Chem., 280, 2005
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1KR4
 | | Structure Genomics, Protein TM1056, cutA | | 分子名称: | Protein TM1056, cutA | | 著者 | Savchenko, A, Zhang, R, Joachimiak, A, Edwards, A, Akarina, T, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2002-01-08 | | 公開日 | 2002-08-14 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | X-ray crystal structure of CutA from Thermotoga maritima at 1.4 A resolution.
Proteins, 54, 2004
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4GYC
 | | Structure of the SRII(D75N mutant)/HtrII Complex in I212121 space group ("U" shape) | | 分子名称: | EICOSANE, RETINAL, Sensory rhodopsin II transducer, ... | | 著者 | Ishchenko, A, Round, E, Borshchevskiy, V, Grudinin, S, Gushchin, I, Klare, J, Remeeva, A, Utrobin, P, Balandin, T, Engelhard, M, Bueldt, G, Gordeliy, V. | | 登録日 | 2012-09-05 | | 公開日 | 2013-05-08 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.0501 Å) | | 主引用文献 | Ground state structure of D75N mutant of sensory rhodopsin II in complex with its cognate transducer.
J Photochem Photobiol B, 123C, 2013
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6S97
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6S6E
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1QW2
 | | Crystal Structure of a Protein of Unknown Function TA1206 from Thermoplasma acidophilum | | 分子名称: | conserved hypothetical protein TA1206 | | 著者 | Savchenko, A, Evdokimova, E, Kudrytska, M, Edwards, A.E, Christendat, D, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2003-08-30 | | 公開日 | 2004-03-09 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure of a Hypothetical Protein "TA1206" from Thermoplasma acidophilum
To be Published
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5JJJ
 | | Structure of the SRII/HtrII Complex in P64 space group ("U" shape) | | 分子名称: | EICOSANE, RETINAL, Sensory rhodopsin II transducer, ... | | 著者 | Ishchenko, A, Round, E, Borshchevskiy, V, Grudinin, S, Gushchin, I, Klare, J, Remeeva, A, Polovinkin, V, Utrobin, P, Balandin, T, Engelhard, M, Bueldt, G, Gordeliy, V. | | 登録日 | 2016-04-24 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex.
Sci Rep, 7, 2017
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5TUD
 | | Structural Insights into the Extracellular Recognition of the Human Serotonin 2B Receptor by an Antibody | | 分子名称: | 5-hydroxytryptamine receptor 2B,Soluble cytochrome b562 chimera, Anti-5-HT2B Fab heavy chain, Anti-5-HT2B Fab light chain, ... | | 著者 | Ishchenko, A, Wacker, D, Kapoor, M, Zhang, A, Han, G.W, Basu, S, Boutet, S, James, D, Wang, D, Weierstall, U, Liu, W, Katritch, V, Stevens, R.C, Cherezov, V. | | 登録日 | 2016-11-05 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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7SZ9
 | | Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabB, and C16:1-crypto Acyl Carrier Protein, AcpP | | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 1, Acyl carrier protein, N~3~-{(2R)-4-[(dihydroxyphosphanyl)oxy]-2-hydroxy-3,3-dimethylbutanoyl}-N-(2-{[(9Z)-hexadec-9-enoyl]amino}ethyl)-beta-alaninamide, ... | | 著者 | Mindrebo, J.T, Chen, A, Noel, J.P, Burkart, M.D. | | 登録日 | 2021-11-26 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mechanism-based cross-linking probes capture the Escherichia coli ketosynthase FabB in conformationally distinct catalytic states.
Acta Crystallogr D Struct Biol, 78, 2022
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8TBG
 | | Tricomplex of RMC-7977, HRAS WT, and CypA | | 分子名称: | (1R,5S,6r)-N-[(1P,7S,9S,13S,20M)-20-{5-(4-cyclopropylpiperazin-1-yl)-2-[(1S)-1-methoxyethyl]pyridin-3-yl}-21-ethyl-17,17-dimethyl-8,14-dioxo-15-oxa-4-thia-9,21,27,28-tetraazapentacyclo[17.5.2.1~2,5~.1~9,13~.0~22,26~]octacosa-1(24),2,5(28),19,22,25-hexaen-7-yl]-3-oxabicyclo[3.1.0]hexane-6-carboxamide, GLYCEROL, GTPase HRas, ... | | 著者 | Chen, A, Tomlinson, A.C.A, Knox, J.E, Yano, J.K. | | 登録日 | 2023-06-28 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy.
Nature, 629, 2024
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1K7K
 | | crystal structure of RdgB- inosine triphosphate pyrophosphatase from E. coli | | 分子名称: | Hypothetical protein yggV | | 著者 | Sanishvili, R, Joachimiak, A, Edwards, A, Savchenko, A, Skarina, T, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2001-10-19 | | 公開日 | 2002-08-14 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Molecular basis of the antimutagenic activity of the house-cleaning inosine triphosphate pyrophosphatase RdgB from Escherichia coli.
J.Mol.Biol., 374, 2007
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7QXR
 | | Azacoelenterazine-bound Renilla-type luciferase (AncFT) | | 分子名称: | 3-(4-hydroxyphenyl)-8-[(4-hydroxyphenyl)methyl]-5-(phenylmethyl)-1$l^{4},4,7,8-tetrazabicyclo[4.3.0]nona-1(6),2,4-trien-9-one, Fragment transplantation onto a hyperstable ancestor of haloalkane dehalogenases and Renilla luciferase (Anc-FT) | | 著者 | Marek, M, Schenkmayerova, A, Janin, Y.L. | | 登録日 | 2022-01-27 | | 公開日 | 2022-12-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.052 Å) | | 主引用文献 | Catalytic mechanism for Renilla-type luciferases
Nat Catal, 2023
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7QXQ
 | | Coelenteramide-bound Renilla-type luciferase (AncFT) | | 分子名称: | Fragment transplantation onto hyperstable ancestor of haloalkane dehalogenases and Renilla luciferase (Anc-FT), N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE | | 著者 | Marek, M, Schenkmayerova, A. | | 登録日 | 2022-01-27 | | 公開日 | 2022-12-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.251 Å) | | 主引用文献 | Catalytic mechanism for Renilla-type luciferases
Nat Catal, 2023
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