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1QIN
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BU of 1qin by Molmil
HUMAN GLYOXALASE I COMPLEXED WITH S-(N-HYDROXY-N-P-IODOPHENYLCARBAMOYL) GLUTATHIONE
分子名称: PROTEIN (LACTOYLGLUTATHIONE LYASE), S-(N-HYDROXY-N-IODOPHENYLCARBAMOYL)GLUTATHIONE, ZINC ION
著者Cameron, A.D, Ridderstrom, M, Olin, B, Mannervik, B.
登録日1999-06-14
公開日1999-11-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue.
Biochemistry, 38, 1999
1QH3
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BU of 1qh3 by Molmil
HUMAN GLYOXALASE II WITH CACODYLATE AND ACETATE IONS PRESENT IN THE ACTIVE SITE
分子名称: ACETATE ION, CACODYLATE ION, CHLORIDE ION, ...
著者Cameron, A.D, Ridderstrom, M, Olin, B, Mannervik, B.
登録日1999-05-10
公開日1999-09-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.
Structure Fold.Des., 7, 1999
1YCB
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BU of 1ycb by Molmil
DISTAL POCKET POLARITY IN LIGAND BINDING TO MYOGLOBIN: DEOXY AND CARBONMONOXY FORMS OF A THREONINE68 (E11) MUTANT INVESTIGATED BY X-RAY CRYSTALLOGRAPHY AND INFRARED SPECTROSCOPY
分子名称: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
著者Cameron, A.D, Smerdon, S.J, Wilkinson, A.J, Habash, J, Helliwell, J.R.
登録日1993-08-10
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Distal pocket polarity in ligand binding to myoglobin: deoxy and carbonmonoxy forms of a threonine68(E11) mutant investigated by X-ray crystallography and infrared spectroscopy.
Biochemistry, 32, 1993
1YCA
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BU of 1yca by Molmil
DISTAL POCKET POLARITY IN LIGAND BINDING TO MYOGLOBIN: DEOXY AND CARBONMONOXY FORMS OF A THREONINE68 (E11) MUTANT INVESTIGATED BY X-RAY CRYSTALLOGRAPHY AND INFRARED SPECTROSCOPY
分子名称: CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
著者Cameron, A.D, Smerdon, S.J, Wilkinson, A.J, Habash, J, Helliwell, J.R.
登録日1993-08-10
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Distal pocket polarity in ligand binding to myoglobin: deoxy and carbonmonoxy forms of a threonine68(E11) mutant investigated by X-ray crystallography and infrared spectroscopy.
Biochemistry, 32, 1993
1QIP
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BU of 1qip by Molmil
HUMAN GLYOXALASE I COMPLEXED WITH S-P-NITROBENZYLOXYCARBONYLGLUTATHIONE
分子名称: BETA-MERCAPTOETHANOL, PROTEIN (LACTOYLGLUTATHIONE LYASE), S-P-NITROBENZYLOXYCARBONYLGLUTATHIONE, ...
著者Cameron, A.D, Ridderstrom, M, Olin, B, Mannervik, B.
登録日1999-06-14
公開日1999-11-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Reaction mechanism of glyoxalase I explored by an X-ray crystallographic analysis of the human enzyme in complex with a transition state analogue.
Biochemistry, 38, 1999
1FRO
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BU of 1fro by Molmil
HUMAN GLYOXALASE I WITH BENZYL-GLUTATHIONE INHIBITOR
分子名称: LACTOYLGLUTATHIONE LYASE, S-BENZYL-GLUTATHIONE, ZINC ION
著者Cameron, A.D, Jones, T.A.
登録日1997-02-25
公開日1997-06-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of human glyoxalase I--evidence for gene duplication and 3D domain swapping.
EMBO J., 16, 1997
1GSE
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BU of 1gse by Molmil
GLUTATHIONE TRANSFERASE A1-1 COMPLEXED WITH AN ETHACRYNIC ACID GLUTATHIONE CONJUGATE (MUTANT R15K)
分子名称: BETA-MERCAPTOETHANOL, ETHACRYNIC ACID, GLUTATHIONE, ...
著者Cameron, A.D, Jones, T.A.
登録日1995-06-09
公開日1995-09-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate.
Structure, 3, 1995
1QH5
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BU of 1qh5 by Molmil
HUMAN GLYOXALASE II WITH S-(N-HYDROXY-N-BROMOPHENYLCARBAMOYL)GLUTATHIONE
分子名称: GLUTATHIONE, PROTEIN (HYDROXYACYLGLUTATHIONE HYDROLASE), S-(N-HYDROXY-N-BROMOPHENYLCARBAMOYL)GLUTATHIONE, ...
著者Cameron, A.D, Ridderstrom, M, Olin, B, Mannervik, B.
登録日1999-05-11
公開日1999-09-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue.
Structure Fold.Des., 7, 1999
1GSF
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BU of 1gsf by Molmil
GLUTATHIONE TRANSFERASE A1-1 COMPLEXED WITH ETHACRYNIC ACID
分子名称: ETHACRYNIC ACID, GLUTATHIONE TRANSFERASE A1-1
著者L'Hermite, G, Sinning, I, Cameron, A.D, Jones, T.A.
登録日1995-06-09
公開日1995-09-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate.
Structure, 3, 1995
1BH5
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BU of 1bh5 by Molmil
HUMAN GLYOXALASE I Q33E, E172Q DOUBLE MUTANT
分子名称: LACTOYLGLUTATHIONE LYASE, S-HEXYLGLUTATHIONE, ZINC ION
著者Cameron, A.D, Jones, T.A.
登録日1998-06-13
公開日1998-11-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Involvement of an active-site Zn2+ ligand in the catalytic mechanism of human glyoxalase I.
J.Biol.Chem., 273, 1998
6H7B
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BU of 6h7b by Molmil
Structure of Leishmania PABP1 (domain J) complexed with a peptide containing the PAM2 motif of eIF4E4.
分子名称: HIS-HIS-MET-ASN-PRO-ASN-ALA-THR-GLU-PHE-MET-PRO, Polyadenylate-binding protein
著者Cameron, A.D, Firczuk, H, dos Santos Rodrigues, F.H, McCarthy, J.E.G.
登録日2018-07-31
公開日2018-12-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献The Leishmania PABP1-eIF4E4 interface: a novel 5'-3' interaction architecture for trans-spliced mRNAs.
Nucleic Acids Res., 47, 2019
6H7A
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BU of 6h7a by Molmil
Structure of Leishmania PABP1 (domain J).
分子名称: PABP1 domain J
著者Cameron, A.D, Firczuk, H, dos Santos Rodrigues, F.H, McCarthy, J.E.G.
登録日2018-07-31
公開日2018-12-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The Leishmania PABP1-eIF4E4 interface: a novel 5'-3' interaction architecture for trans-spliced mRNAs.
Nucleic Acids Res., 47, 2019
1GSD
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BU of 1gsd by Molmil
GLUTATHIONE TRANSFERASE A1-1 IN UNLIGANDED FORM
分子名称: GLUTATHIONE TRANSFERASE A1-1
著者L'Hermite, G, Sinning, I, Cameron, A.D, Jones, T.A.
登録日1995-06-09
公開日1995-09-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate.
Structure, 3, 1995
2J50
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BU of 2j50 by Molmil
Structure of Aurora-2 in complex with PHA-739358
分子名称: N-[(3E)-5-[(2R)-2-METHOXY-2-PHENYLACETYL]PYRROLO[3,4-C]PYRAZOL-3(5H)-YLIDENE]-4-(4-METHYLPIPERAZIN-1-YL)BENZAMIDE, SERINE/THREONINE-PROTEIN KINASE 6, SULFATE ION
著者Cameron, A.D, Izzo, G, Storici, P, Rusconi, L, Fancelli, D, Varasi, M, Berta, D, Bindi, S, Forte, B, Severino, D, Tonani, R, Vianello, P.
登録日2006-09-08
公開日2006-11-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献1,4,5,6-Tetrahydropyrrolo[3,4-C]Pyrazoles: Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile.
J.Med.Chem., 49, 2006
2JGB
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BU of 2jgb by Molmil
Structure of human eIF4E homologous protein 4EHP with m7GTP
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1
著者Cameron, A.D, Rosettani, P, Knapp, S, Vismara, M.G, Rusconi, L.
登録日2007-02-12
公開日2007-02-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.
J. Mol. Biol., 368, 2007
2JGC
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BU of 2jgc by Molmil
Structure of the human eIF4E homologous protein, 4EHP without ligand bound
分子名称: EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 2, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1
著者Cameron, A.D, Rosettani, P, Knapp, S, Vismara, M.G, Rusconi, L.
登録日2007-02-12
公開日2007-02-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.
J. Mol. Biol., 368, 2007
3ZUY
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BU of 3zuy by Molmil
Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT.
分子名称: LAURYL DIMETHYLAMINE-N-OXIDE, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ...
著者Hu, N.-J, Iwata, S, Cameron, A.D, Drew, D.
登録日2011-07-21
公開日2011-10-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of a Bacterial Homologue of the Bile Acid Sodium Symporter Asbt.
Nature, 478, 2011
3ZUX
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BU of 3zux by Molmil
Crystal structure of a bacterial homologue of the bile acid sodium symporter ASBT.
分子名称: LAURYL DIMETHYLAMINE-N-OXIDE, MERCURY (II) ION, PHOSPHATIDYLETHANOLAMINE, ...
著者Hu, N.-J, Iwata, S, Cameron, A.D, Drew, D.
登録日2011-07-21
公開日2011-10-12
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of a Bacterial Homologue of the Bile Acid Sodium Symporter Asbt.
Nature, 478, 2011
8QA2
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BU of 8qa2 by Molmil
Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; Nconst-mon conformation
分子名称: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
著者Brotherton, D.H, Cameron, A.D.
登録日2023-08-22
公開日2024-06-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8OYF
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BU of 8oyf by Molmil
Crystal structure of ASBTNM in lipidic cubic phase without substrate bound
分子名称: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, NICKEL (II) ION, PHOSPHATIDYLETHANOLAMINE, ...
著者Becker, P, Cameron, A.D.
登録日2023-05-04
公開日2023-07-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mechanism of substrate binding and transport in BASS transporters.
Biorxiv, 2023
8QA1
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BU of 8qa1 by Molmil
Cryo-EM structure of Cx26 solubilised in LMNG - Hemichannel classification NFlex conformation
分子名称: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
著者Brotherton, D.H, Cameron, A.D.
登録日2023-08-22
公開日2024-06-12
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8OYG
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BU of 8oyg by Molmil
Crystal structure of ASBTNM in complex with pantoate
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CADMIUM ION, PANTOATE, ...
著者Becker, P, Cameron, A.D.
登録日2023-05-04
公開日2023-07-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mechanism of substrate binding and transport in BASS transporters.
Biorxiv, 2023
8Q9Z
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BU of 8q9z by Molmil
Cryo-EM structure of Cx26 gap junction K125E mutant in bicarbonate buffer (classification on hemichannel)
分子名称: DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
著者Brotherton, D.H, Cameron, A.D.
登録日2023-08-22
公開日2024-06-12
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8QA0
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BU of 8qa0 by Molmil
Cryo-EM structure of Cx26 solubilised in LMNG - hemichannel classification - NConst conformation
分子名称: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
著者Brotherton, D.H, Cameron, A.D.
登録日2023-08-22
公開日2024-06-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8QA3
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BU of 8qa3 by Molmil
Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; NFlex conformation
分子名称: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
著者Brotherton, D.H, Cameron, A.D.
登録日2023-08-22
公開日2024-06-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024

 

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