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3UGM
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BU of 3ugm by Molmil
Structure of TAL effector PthXo1 bound to its DNA target
分子名称: DNA-1, DNA-2, TAL effector AvrBs3/PthA
著者Mak, A.N.S, Bradley, P, Cernadas, R.A, Bogdanove, A.J, Stoddard, B.L.
登録日2011-11-02
公開日2012-01-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Crystal Structure of TAL Effector PthXo1 Bound to Its DNA Target.
Science, 335, 2012
8ETQ
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BU of 8etq by Molmil
Designed pentafoil knot protein folded into a trefoil knot
分子名称: k-cTRP5
著者Doyle, L.A, Kibler, R.D, Bradley, P, Stoddard, B.L.
登録日2022-10-17
公開日2023-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献De novo design of knotted tandem repeat proteins.
Nat Commun, 14, 2023
6XR1
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BU of 6xr1 by Molmil
Computationally designed right-handed alpha/alpha single-chain toroid with 9 repeats
分子名称: dTor_9x57R
著者Hallinan, J.P, Doyle, L, Bradley, P, Stoddard, B.L.
登録日2020-07-10
公開日2021-07-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Design of functionalised circular tandem repeat proteins with longer repeat topologies and enhanced subunit contact surfaces.
Commun Biol, 4, 2021
6XR2
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BU of 6xr2 by Molmil
Computationally designed right-handed alpha/alpha homotrimeric toroid with 3 repeats per subunit
分子名称: dTor_3x57R
著者Hallinan, J.P, Doyle, L, Bradley, P, Stoddard, B.L.
登録日2020-07-10
公開日2021-07-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Design of functionalised circular tandem repeat proteins with longer repeat topologies and enhanced subunit contact surfaces.
Commun Biol, 4, 2021
4YXX
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BU of 4yxx by Molmil
Computationally designed left-handed alpha/alpha toroid with 6 repeats
分子名称: dTor_6x35L
著者Doyle, L, Bolduc, J, Stoddard, B.L, Bradley, P.
登録日2015-03-23
公開日2015-12-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4YY2
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BU of 4yy2 by Molmil
Computationally designed left-handed alpha/alpha toroid with 3 repeats in space group P212121
分子名称: SODIUM ION, dTor_3x33L
著者Hallinan, J.P, Bradley, P, Stoddard, B.L.
登録日2015-03-23
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.854 Å)
主引用文献Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4YXY
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BU of 4yxy by Molmil
Computationally designed left-handed alpha/alpha toroid with 9 repeats; two linked rings of 12 repeats each structure
分子名称: dTor_9x31L
著者Doyle, L, Stoddard, B.L, Bradley, P.
登録日2015-03-23
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.203 Å)
主引用文献Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4YY5
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BU of 4yy5 by Molmil
Computationally designed left-handed alpha/alpha toroid with 3 repeats in space group P43212
分子名称: dTor_3x33L
著者Hallinan, J.P, Bradley, P, Stoddard, B.L.
登録日2015-03-23
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
4YXZ
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BU of 4yxz by Molmil
Computationally designed left-handed alpha/alpha toroid with 9 repeats
分子名称: dTor_9x31L
著者Doyle, L, Stoddard, B.L, Bradley, P.
登録日2015-03-23
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.496 Å)
主引用文献Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
7SQ4
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BU of 7sq4 by Molmil
Designed trefoil knot protein, variant 2
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Designed trefoil knot protein, variant 2, ...
著者Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P.
登録日2021-11-04
公開日2022-06-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.493 Å)
主引用文献De novo design of knotted tandem repeat proteins.
Nat Commun, 14, 2023
7SQ3
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BU of 7sq3 by Molmil
Designed trefoil knot protein, variant 1
分子名称: CHLORIDE ION, Designed trefoil knot protein, variant 1, ...
著者Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P.
登録日2021-11-04
公開日2022-06-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.453 Å)
主引用文献De novo design of knotted tandem repeat proteins.
Nat Commun, 14, 2023
7SQ5
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BU of 7sq5 by Molmil
Designed trefoil knot protein, variant 3
分子名称: Designed trefoil knot protein, variant 3, SODIUM ION
著者Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P.
登録日2021-11-04
公開日2022-11-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.205 Å)
主引用文献De novo design of knotted tandem repeat proteins.
Nat Commun, 14, 2023
5BYO
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BU of 5byo by Molmil
Computationally designed left-handed alpha/alpha toroid with 12 repeats
分子名称: dTor_12x31L
著者Doyle, L, Stoddard, B.L, Bradley, P.
登録日2015-06-10
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Rational design of alpha-helical tandem repeat proteins with closed architectures.
Nature, 528, 2015
5JO3
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BU of 5jo3 by Molmil
PDE5A for NaV1.7
分子名称: 1-(5-chloro-6-methoxypyridin-3-yl)-3-methyl-N-(methylsulfonyl)-1H-indazole-5-carboxamide, ZINC ION, cGMP-specific 3',5'-cyclic phosphodiesterase
著者Storer, I, Chrencik, J.
登録日2016-05-01
公開日2017-05-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献PDE5A for NaV1.7
To be published
4PLB
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BU of 4plb by Molmil
Crystal Structure of S.A. gyrase-AM8191 complex
分子名称: 6-[({(1r,4S)-1-[(1S)-2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)-1-hydroxyethyl]-2-oxabicyclo[2.2.2]oct-4-yl}amino)methyl]-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one, Chimera protein of DNA gyrase subunits B and A, DNA (5'-D(P*AP*GP*CP*CP*GP*TP*AP*GP*GP*GP*CP*CP*CP*TP*AP*CP*GP*GP*CP*T)-3'), ...
著者Lu, J, Patel, S, Soisson, S.
登録日2014-05-16
公開日2014-06-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad spectrum antibacterial agents.
Acs Med.Chem.Lett., 5, 2014
6MAF
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BU of 6maf by Molmil
native BbvCI A2B2 tetramer at low resolution
分子名称: BbvCI endonuclease subunit 1, BbvCI endonuclease subunit 2
著者Shen, B.W, Stoddard, B.L.
登録日2018-08-27
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.79 Å)
主引用文献Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI.
Nucleic Acids Res., 47, 2019
6M9G
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BU of 6m9g by Molmil
BbvCI B2 dimer with Ta6Br14 clusters
分子名称: 1,2-ETHANEDIOL, ACETATE ION, BROMIDE ION, ...
著者Shen, B.W, Stoddard, B.L.
登録日2018-08-23
公開日2018-11-14
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI.
Nucleic Acids Res., 47, 2019
6MAG
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BU of 6mag by Molmil
native BbvCI B2 dimer in space group C222
分子名称: ACETATE ION, BbvCI endonuclease subunit 2, GLYCEROL, ...
著者Shen, B.W, Stoddard, B.L.
登録日2018-08-27
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI.
Nucleic Acids Res., 47, 2019
6EG7
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BU of 6eg7 by Molmil
BbvCI B2 dimer with I3C clusters
分子名称: 1,2-ETHANEDIOL, 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, BbvCI endonuclease subunit 2, ...
著者Shen, B.W, Stoddard, B.L.
登録日2018-08-19
公開日2018-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure, subunit organization and behavior of the asymmetric Type IIT restriction endonuclease BbvCI.
Nucleic Acids Res., 47, 2019
7RDR
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BU of 7rdr by Molmil
Circular tandem repeat protein with novel repeat topology and enhanced subunit contact surfaces
分子名称: Circular tendon repeat protein
著者Shen, B.W, Stoddard, B.L.
登録日2021-07-10
公開日2021-09-01
最終更新日2021-11-17
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Design of functionalised circular tandem repeat proteins with longer repeat topologies and enhanced subunit contact surfaces.
Commun Biol, 4, 2021

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