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4I11
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BU of 4i11 by Molmil
Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartates.
分子名称: Beta-secretase 1, N-(3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-L-phenylalanine, ZINC ION
著者Bowers, B, Xu, Y, Yuan, S, Probst, G.D, Hom, R.K, Chan, W, Konradi, A.W, Sham, H.L, Zhu, Y.L, Beroza, P, Pan, H, Brecht, E, Yao, N, Lougheed, J, Artis, D.R, Tam, D, Bova, M.
登録日2012-11-19
公開日2013-03-06
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartates.
Bioorg.Med.Chem.Lett., 23, 2013
1TG6
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BU of 1tg6 by Molmil
Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP
分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, GLYCEROL, ...
著者Kang, S.G, Maurizi, M.R, Thompson, M, Mueser, T, Ahvazi, B.
登録日2004-05-28
公開日2005-03-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP
J.Struct.Biol., 148, 2004
1TYF
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BU of 1tyf by Molmil
THE STRUCTURE OF CLPP AT 2.3 ANGSTROM RESOLUTION SUGGESTS A MODEL FOR ATP-DEPENDENT PROTEOLYSIS
分子名称: CLP PEPTIDASE
著者Wang, J, Hartling, J.A, Flanagan, J.M.
登録日1997-10-13
公開日1998-06-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of ClpP at 2.3 A resolution suggests a model for ATP-dependent proteolysis.
Cell(Cambridge,Mass.), 91, 1997

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件を2024-08-21に公開中

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