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Crystal structure of DIRAS 2/3 chimera in complex with GDP
分子名称:	1,2-ETHANEDIOL, GLYCEROL, GTP-binding protein Di-Ras2,GTP-binding protein Di-Ras3,GTP-binding protein Di-Ras2, ...
著者	Gilbert, Y.H, Reger, A, Sharma, R, Bast, J, Kim, C.
登録日	2018-12-06
公開日	2019-12-18
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (3.081 Å)
主引用文献	Crystal structure of DIRAS 2/3 chimera in complex with GDP To Be Published

The crystal structure of Human VPS34 in complex with PIK-III
分子名称:	4'-(cyclopropylmethyl)-N~2~-(pyridin-4-yl)-4,5'-bipyrimidine-2,2'-diamine, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3
著者	Knapp, M.S, Elling, R.A.
登録日	2014-05-04
公開日	2014-10-29
最終更新日	2023-12-27
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat.Cell Biol., 16, 2014

Crystal structure of Beta-catenin Armadillo repeats domain in complex with the inhibitor RS6452
分子名称:	4-bromanyl-~{N}-(3-pyridin-2-ylphenyl)benzenesulfonamide, Catenin beta-1
著者	Capelli, D, Pochetti, G, Montanari, R.
登録日	2022-05-04
公開日	2023-05-17
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (3.434 Å)
主引用文献	Novel N -(Heterocyclylphenyl)benzensulfonamide Sharing an Unreported Binding Site with T-Cell Factor 4 at the beta-Catenin Armadillo Repeats Domain as an Anticancer Agent. Acs Pharmacol Transl Sci, 6, 2023

structure of human CD73 in complex with antibody IPH53
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-nucleotidase, IPH53 heavy chain, ...
著者	Roussel, A, Amigues, B.
登録日	2018-10-18
公開日	2019-08-28
最終更新日	2024-10-09
実験手法	X-RAY DIFFRACTION (2.78 Å)
主引用文献	Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies. Cell Rep, 27, 2019