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Crystal structure of the kinase domain of EGFR exon-19 (del-747-749) mutant
分子名称:	Epidermal growth factor receptor
著者	Ashtekar, K.D, Stayrook, S.E, Lemmon, M.A.
登録日	2022-02-04
公開日	2022-02-16
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2.96 Å)
主引用文献	Biochemical and structural basis for differential inhibitor sensitivity of EGFR with distinct exon 19 mutations. Nat Commun, 13, 2022

Ralimetinib (LY2228820) in complex with wild type EGFR
分子名称:	Epidermal growth factor receptor, ralimetinib
著者	Chitnis, S.P, Heppner, D.E.
登録日	2023-02-14
公開日	2023-10-11
最終更新日	2024-04-24
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Inhibition of a lower potency target drives the anticancer activity of a clinical p38 inhibitor. Cell Chem Biol, 30, 2023