5XEV
 
 | | Crystal Structure of a novel Xaa-Pro dipeptidase from Deinococcus radiodurans | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Are, V.N, Kumar, A, Ghosh, B, Makde, R.D. | | 登録日 | 2017-04-06 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structure of a novel prolidase from Deinococcus radiodurans identifies new subfamily of bacterial prolidases.
Proteins, 85, 2017
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5GIQ
 | | Xaa-Pro peptidase from Deinococcus radiodurans, Zinc bound | | 分子名称: | PHOSPHATE ION, Proline dipeptidase, ZINC ION | | 著者 | Are, V.N, Singh, R, Kumar, A, Ghosh, B, Jamdar, S.N, Makde, R.D. | | 登録日 | 2016-06-24 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures and activities of widely conserved small prokaryotic aminopeptidases-P clarify classification of M24B peptidases.
Proteins, 2018
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5GIU
 | | Crystal structure of Xaa-Pro peptidase from Deinococcus radiodurans, metal-free active site | | 分子名称: | PHOSPHATE ION, Proline dipeptidase, SODIUM ION | | 著者 | Are, V.N, Kumar, A, Singh, R, Ghosh, B, Jamdar, S.N, Makde, R.D. | | 登録日 | 2016-06-25 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Xaa-Pro peptidase from Deinococcus radiodurans, metal-free active site
To Be Published
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5CE6
 | | N-terminal domain of FACT complex subunit SPT16 from Cicer arietinum (chickpea) | | 分子名称: | ACETATE ION, FACT-Spt16, POTASSIUM ION, ... | | 著者 | Are, V.N, Ghosh, B, Kumar, A, Makde, R. | | 登録日 | 2015-07-06 | | 公開日 | 2016-04-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure and dynamics of Spt16N-domain of FACT complex from Cicer arietinum.
Int.J.Biol.Macromol., 88, 2016
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7QZW
 | | Hm-AMP8 | | 分子名称: | Hm-AMP8 | | 著者 | Grafskaia, E.N, Pavlova, E.R, Latsis, I.A, Malakhova, M.V, Lavrenova, V.N, Ivchenkov, D.V, Bashkirov, P.V, Kot, E.F, Mineev, K.S, Arseniev, A.S, Klinov, D.V, Lazarev, V.N. | | 登録日 | 2022-02-01 | | 公開日 | 2023-02-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The study of the interaction of cationic peptides from a medical leech with blood components as a first step to the systemic use of antimicrobial peptides for therapy of infectious diseases
To Be Published
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7QZV
 | | Hm-AMP2 | | 分子名称: | Hm-AMP2 | | 著者 | Grafskaia, E.N, Pavlova, E.R, Latsis, I.A, Malakhova, M.V, Lavrenova, V.N, Ivchenkov, D.V, Bashkirov, P.V, Kot, E.F, Mineev, K.S, Arseniev, A.S, Klinov, D.V, Lazarev, V.N. | | 登録日 | 2022-02-01 | | 公開日 | 2022-11-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Non-toxic antimicrobial peptide Hm-AMP2 from leech metagenome proteins identified by the gradient-boosting approach
Materials, 224, 2022
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4R60
 | | Crystal Structure of Xaa-Pro dipeptidase from Xanthomonas campestris | | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, Proline dipeptidase, ... | | 著者 | Kumar, A, Ghosh, B, Are, V.N, Jamdar, S.N, Makde, R.D, Sharma, S.M. | | 登録日 | 2014-08-22 | | 公開日 | 2014-09-17 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Crystal Structure of Xaa-Pro dipeptidase from Xanthomonas campestris
to be published
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6RRO
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6RRL
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6RSM
 | | Solution NMR structure of the peptide 12530 from medicinal leech Hirudo medicinalis in dodecylphosphocholine micelles | | 分子名称: | peptide 12530 | | 著者 | Talyzina, I.A, Nadezhdin, K.D, Grafskaia, E.N, Arseniev, A.S, Lazarev, V.N. | | 登録日 | 2019-05-21 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Medicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens.
Eur.J.Med.Chem., 180, 2019
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5FCH
 | | Crystal Structure of Xaa-Pro dipeptidase from Xanthomonas campestris, phosphate and Zn bound | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLY-GLY-GLY, GLYCEROL, ... | | 著者 | Kumar, A, Are, V, Ghosh, B, Jamdar, S, Makde, R.D. | | 登録日 | 2015-12-15 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases
Biochim. Biophys. Acta, 1865, 2017
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5FCF
 | | Crystal Structure of Xaa-Pro dipeptidase from Xanthomonas campestris, phosphate and Mn bound | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLY-GLY-GLY, GLYCEROL, ... | | 著者 | Kumar, A, Are, V, Ghosh, B, Jamdar, S, Makde, R.D. | | 登録日 | 2015-12-15 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases.
Biochim. Biophys. Acta, 1865, 2017
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5CNX
 | | Crystal structure of Xaa-Pro aminopeptidase from Escherichia coli K12 | | 分子名称: | Aminopeptidase YpdF, CACODYLATE ION, GLYCEROL, ... | | 著者 | Kumar, A, Are, V, Ghosh, B, Jamdar, S, Makde, R.D. | | 登録日 | 2015-07-18 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures and activities of widely conserved small prokaryotic aminopeptidases-P clarify classification of M24B peptidases
Proteins, 2018
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8BBU
 | | Crystal structure of medical leech destabilase (high salt) | | 分子名称: | GLYCEROL, Lysozyme, MALONATE ION, ... | | 著者 | Marin, E, Bukhdruker, S, Manuvera, V, Kornilov, D, Zinovev, E, Bobrovsky, P, Lazarev, V, Borshchevskiy, V. | | 登録日 | 2022-10-14 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Structural insights into thrombolytic activity of destabilase from medicinal leech.
Sci Rep, 13, 2023
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8BBW
 | | Crystal structure of medical leech destabilase (low salt) | | 分子名称: | CHLORIDE ION, GLYCEROL, Lysozyme | | 著者 | Marin, E, Bukhdruker, S, Manuvera, V, Kornilov, D, Zinovev, E, Bobrovsky, P, Lazarev, V, Borshchevskiy, V. | | 登録日 | 2022-10-14 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-08-21 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural insights into thrombolytic activity of destabilase from medicinal leech.
Sci Rep, 13, 2023
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6A8M
 | | N-terminal domain of FACT complex subunit SPT16 from Eremothecium gossypii (Ashbya gossypii) | | 分子名称: | FACT complex subunit SPT16 | | 著者 | Gaur, N.K, Are, V.N, Durani, V, Ghosh, B, Kumar, A, Kulkarni, K, Makde, R.D. | | 登録日 | 2018-07-09 | | 公開日 | 2018-08-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Evolutionary conservation of protein dynamics: insights from all-atom molecular dynamics simulations of 'peptidase' domain of Spt16.
J.Biomol.Struct.Dyn., 2021
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7OXL
 | | Crystal structure of human Spermine Oxidase | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, FAD-MDL72527 adduct, ... | | 著者 | Impagliazzo, A, Johannsson, S, Thomsen, M, Krapp, S. | | 登録日 | 2021-06-22 | | 公開日 | 2022-07-13 | | 最終更新日 | 2022-08-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor.
Commun Biol, 5, 2022
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7OY0
 | | Structure of human Spermine Oxidase in complex with a highly selective allosteric inhibitor | | 分子名称: | 4-[(4-imidazo[1,2-a]pyridin-3-yl-1,3-thiazol-2-yl)amino]phenol, CHLORIDE ION, FAD-MDL72527 adduct, ... | | 著者 | Impagliazzo, A, Thomsen, M, Johannsson, S, Krapp, S. | | 登録日 | 2021-06-23 | | 公開日 | 2022-07-13 | | 最終更新日 | 2022-08-17 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor.
Commun Biol, 5, 2022
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