5XEV
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![BU of 5xev by Molmil](/molmil-images/mine/5xev) | Crystal Structure of a novel Xaa-Pro dipeptidase from Deinococcus radiodurans | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Are, V.N, Kumar, A, Ghosh, B, Makde, R.D. | 登録日 | 2017-04-06 | 公開日 | 2017-10-18 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal structure of a novel prolidase from Deinococcus radiodurans identifies new subfamily of bacterial prolidases. Proteins, 85, 2017
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5GIQ
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![BU of 5giq by Molmil](/molmil-images/mine/5giq) | Xaa-Pro peptidase from Deinococcus radiodurans, Zinc bound | 分子名称: | PHOSPHATE ION, Proline dipeptidase, ZINC ION | 著者 | Are, V.N, Singh, R, Kumar, A, Ghosh, B, Jamdar, S.N, Makde, R.D. | 登録日 | 2016-06-24 | 公開日 | 2017-06-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structures and activities of widely conserved small prokaryotic aminopeptidases-P clarify classification of M24B peptidases. Proteins, 2018
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5GIU
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![BU of 5giu by Molmil](/molmil-images/mine/5giu) | Crystal structure of Xaa-Pro peptidase from Deinococcus radiodurans, metal-free active site | 分子名称: | PHOSPHATE ION, Proline dipeptidase, SODIUM ION | 著者 | Are, V.N, Kumar, A, Singh, R, Ghosh, B, Jamdar, S.N, Makde, R.D. | 登録日 | 2016-06-25 | 公開日 | 2017-06-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Xaa-Pro peptidase from Deinococcus radiodurans, metal-free active site To Be Published
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5CE6
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![BU of 5ce6 by Molmil](/molmil-images/mine/5ce6) | N-terminal domain of FACT complex subunit SPT16 from Cicer arietinum (chickpea) | 分子名称: | ACETATE ION, FACT-Spt16, POTASSIUM ION, ... | 著者 | Are, V.N, Ghosh, B, Kumar, A, Makde, R. | 登録日 | 2015-07-06 | 公開日 | 2016-04-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure and dynamics of Spt16N-domain of FACT complex from Cicer arietinum. Int.J.Biol.Macromol., 88, 2016
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7QZW
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![BU of 7qzw by Molmil](/molmil-images/mine/7qzw) | Hm-AMP8 | 分子名称: | Hm-AMP8 | 著者 | Grafskaia, E.N, Pavlova, E.R, Latsis, I.A, Malakhova, M.V, Lavrenova, V.N, Ivchenkov, D.V, Bashkirov, P.V, Kot, E.F, Mineev, K.S, Arseniev, A.S, Klinov, D.V, Lazarev, V.N. | 登録日 | 2022-02-01 | 公開日 | 2023-02-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The study of the interaction of cationic peptides from a medical leech with blood components as a first step to the systemic use of antimicrobial peptides for therapy of infectious diseases To Be Published
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7QZV
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![BU of 7qzv by Molmil](/molmil-images/mine/7qzv) | Hm-AMP2 | 分子名称: | Hm-AMP2 | 著者 | Grafskaia, E.N, Pavlova, E.R, Latsis, I.A, Malakhova, M.V, Lavrenova, V.N, Ivchenkov, D.V, Bashkirov, P.V, Kot, E.F, Mineev, K.S, Arseniev, A.S, Klinov, D.V, Lazarev, V.N. | 登録日 | 2022-02-01 | 公開日 | 2022-11-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Non-toxic antimicrobial peptide Hm-AMP2 from leech metagenome proteins identified by the gradient-boosting approach Materials, 224, 2022
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4R60
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![BU of 4r60 by Molmil](/molmil-images/mine/4r60) | Crystal Structure of Xaa-Pro dipeptidase from Xanthomonas campestris | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, Proline dipeptidase, ... | 著者 | Kumar, A, Ghosh, B, Are, V.N, Jamdar, S.N, Makde, R.D, Sharma, S.M. | 登録日 | 2014-08-22 | 公開日 | 2014-09-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Crystal Structure of Xaa-Pro dipeptidase from Xanthomonas campestris to be published
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6RRO
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![BU of 6rro by Molmil](/molmil-images/mine/6rro) | |
6RRL
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![BU of 6rrl by Molmil](/molmil-images/mine/6rrl) | |
6RSM
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![BU of 6rsm by Molmil](/molmil-images/mine/6rsm) | Solution NMR structure of the peptide 12530 from medicinal leech Hirudo medicinalis in dodecylphosphocholine micelles | 分子名称: | peptide 12530 | 著者 | Talyzina, I.A, Nadezhdin, K.D, Grafskaia, E.N, Arseniev, A.S, Lazarev, V.N. | 登録日 | 2019-05-21 | 公開日 | 2019-07-24 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Medicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens. Eur.J.Med.Chem., 180, 2019
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5FCH
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![BU of 5fch by Molmil](/molmil-images/mine/5fch) | Crystal Structure of Xaa-Pro dipeptidase from Xanthomonas campestris, phosphate and Zn bound | 分子名称: | DI(HYDROXYETHYL)ETHER, GLY-GLY-GLY, GLYCEROL, ... | 著者 | Kumar, A, Are, V, Ghosh, B, Jamdar, S, Makde, R.D. | 登録日 | 2015-12-15 | 公開日 | 2016-12-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases Biochim. Biophys. Acta, 1865, 2017
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5FCF
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![BU of 5fcf by Molmil](/molmil-images/mine/5fcf) | Crystal Structure of Xaa-Pro dipeptidase from Xanthomonas campestris, phosphate and Mn bound | 分子名称: | DI(HYDROXYETHYL)ETHER, GLY-GLY-GLY, GLYCEROL, ... | 著者 | Kumar, A, Are, V, Ghosh, B, Jamdar, S, Makde, R.D. | 登録日 | 2015-12-15 | 公開日 | 2016-12-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases. Biochim. Biophys. Acta, 1865, 2017
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5CNX
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![BU of 5cnx by Molmil](/molmil-images/mine/5cnx) | Crystal structure of Xaa-Pro aminopeptidase from Escherichia coli K12 | 分子名称: | Aminopeptidase YpdF, CACODYLATE ION, GLYCEROL, ... | 著者 | Kumar, A, Are, V, Ghosh, B, Jamdar, S, Makde, R.D. | 登録日 | 2015-07-18 | 公開日 | 2016-07-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structures and activities of widely conserved small prokaryotic aminopeptidases-P clarify classification of M24B peptidases Proteins, 2018
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8BBU
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![BU of 8bbu by Molmil](/molmil-images/mine/8bbu) | Crystal structure of medical leech destabilase (high salt) | 分子名称: | GLYCEROL, Lysozyme, MALONATE ION, ... | 著者 | Marin, E, Bukhdruker, S, Manuvera, V, Kornilov, D, Zinovev, E, Bobrovsky, P, Lazarev, V, Borshchevskiy, V. | 登録日 | 2022-10-14 | 公開日 | 2023-02-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Structural insights into thrombolytic activity of destabilase from medicinal leech. Sci Rep, 13, 2023
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8BBW
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![BU of 8bbw by Molmil](/molmil-images/mine/8bbw) | Crystal structure of medical leech destabilase (low salt) | 分子名称: | CHLORIDE ION, GLYCEROL, Lysozyme | 著者 | Marin, E, Bukhdruker, S, Manuvera, V, Kornilov, D, Zinovev, E, Bobrovsky, P, Lazarev, V, Borshchevskiy, V. | 登録日 | 2022-10-14 | 公開日 | 2023-02-08 | 最終更新日 | 2024-08-21 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural insights into thrombolytic activity of destabilase from medicinal leech. Sci Rep, 13, 2023
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6A8M
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![BU of 6a8m by Molmil](/molmil-images/mine/6a8m) | N-terminal domain of FACT complex subunit SPT16 from Eremothecium gossypii (Ashbya gossypii) | 分子名称: | FACT complex subunit SPT16 | 著者 | Gaur, N.K, Are, V.N, Durani, V, Ghosh, B, Kumar, A, Kulkarni, K, Makde, R.D. | 登録日 | 2018-07-09 | 公開日 | 2018-08-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Evolutionary conservation of protein dynamics: insights from all-atom molecular dynamics simulations of 'peptidase' domain of Spt16. J.Biomol.Struct.Dyn., 2021
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7OXL
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![BU of 7oxl by Molmil](/molmil-images/mine/7oxl) | Crystal structure of human Spermine Oxidase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, FAD-MDL72527 adduct, ... | 著者 | Impagliazzo, A, Johannsson, S, Thomsen, M, Krapp, S. | 登録日 | 2021-06-22 | 公開日 | 2022-07-13 | 最終更新日 | 2022-08-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor. Commun Biol, 5, 2022
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7OY0
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![BU of 7oy0 by Molmil](/molmil-images/mine/7oy0) | Structure of human Spermine Oxidase in complex with a highly selective allosteric inhibitor | 分子名称: | 4-[(4-imidazo[1,2-a]pyridin-3-yl-1,3-thiazol-2-yl)amino]phenol, CHLORIDE ION, FAD-MDL72527 adduct, ... | 著者 | Impagliazzo, A, Thomsen, M, Johannsson, S, Krapp, S. | 登録日 | 2021-06-23 | 公開日 | 2022-07-13 | 最終更新日 | 2022-08-17 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor. Commun Biol, 5, 2022
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