2VL1
 
 | | Crystal structure of beta-alanine synthase from Saccharomyces kluyveri in complex with a gly-gly peptide | | 分子名称: | BETA-ALANINE SYNTHASE, GLYCINE, ZINC ION | | 著者 | Andersen, B, Lundgren, S, Dobritzsch, D, Piskur, J. | | 登録日 | 2008-01-07 | | 公開日 | 2008-05-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | A Recruited Protease is Involved in Catabolism of Pyrimidines.
J.Mol.Biol., 379, 2008
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6QPP
 | | Rhizomucor miehei lipase propeptide complex, native | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Lipase | | 著者 | Moroz, O.V, Blagova, E, Reiser, V, Saikia, R, Dalal, S, Jorgensen, C.I, Baunsgaard, L, Andersen, B, Svendsen, A, Wilson, K.S. | | 登録日 | 2019-02-14 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Novel Inhibitory Function of theRhizomucor mieheiLipase Propeptide and Three-Dimensional Structures of Its Complexes with the Enzyme.
Acs Omega, 4, 2019
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6QPR
 | | Rhizomucor miehei lipase propeptide complex, Ser95/Ile96 deletion mutant | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Lipase | | 著者 | Moroz, O.V, Blagova, E, Reiser, V, Saikia, R, Dalal, S, Jorgensen, C.I, Baunsgaard, L, Andersen, B, Svendsen, A, Wilson, K.S. | | 登録日 | 2019-02-14 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Novel Inhibitory Function of theRhizomucor mieheiLipase Propeptide and Three-Dimensional Structures of Its Complexes with the Enzyme.
Acs Omega, 4, 2019
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2V8G
 | | Crystal structure of beta-alanine synthase from Saccharomyces kluyveri in complex with the product beta-alanine | | 分子名称: | BETA-ALANINE, BETA-ALANINE SYNTHASE, BICINE, ... | | 著者 | Lundgren, S, Andersen, B, Piskur, J, Dobritzsch, D. | | 登録日 | 2007-08-07 | | 公開日 | 2007-10-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements.
J.Biol.Chem., 282, 2007
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2V8V
 | | Crystal structure of mutant R322A of beta-alanine synthase from Saccharomyces kluyveri | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BETA-ALANINE SYNTHASE, N-(AMINOCARBONYL)-BETA-ALANINE, ... | | 著者 | Lundgren, S, Andersen, B, Piskur, J, Dobritzsch, D. | | 登録日 | 2007-08-15 | | 公開日 | 2007-10-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements.
J.Biol.Chem., 282, 2007
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2V8D
 | | Crystal structure of mutant E159A of beta-alanine synthase from Saccharomyces kluyveri | | 分子名称: | BETA-ALANINE SYNTHASE, ZINC ION | | 著者 | Lundgren, S, Andersen, B, Piskur, J, Dobritzsch, D. | | 登録日 | 2007-08-07 | | 公開日 | 2007-10-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements.
J.Biol.Chem., 282, 2007
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2V8H
 | | Crystal structure of mutant E159A of beta-alanine synthase from Saccharomyces kluyveri in complex with its substrate N-carbamyl-beta- alanine | | 分子名称: | BETA-ALANINE SYNTHASE, BICINE, N-(AMINOCARBONYL)-BETA-ALANINE, ... | | 著者 | Lundgren, S, Andersen, B, Piskur, J, Dobritzsch, D. | | 登録日 | 2007-08-08 | | 公開日 | 2007-10-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structures of Yeast -Alanine Synthase Complexes Reveal the Mode of Substrate Binding and Large Scale Domain Closure Movements.
J.Biol.Chem., 282, 2007
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2VHH
 | | Crystal structure of a pyrimidine degrading enzyme from Drosophila melanogaster | | 分子名称: | CG3027-PA | | 著者 | Lundgren, S, Lohkamp, B, Andersen, B, Piskur, J, Dobritzsch, D. | | 登録日 | 2007-11-21 | | 公開日 | 2008-03-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The Crystal Structure of Beta-Alanine Synthase from Drosophila Melanogaster Reveals a Homooctameric Helical Turn-Like Assembly.
J.Mol.Biol., 377, 2008
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2VHI
 | | Crystal structure of a pyrimidine degrading enzyme from Drosophila melanogaster | | 分子名称: | CG3027-PA | | 著者 | Lundgren, S, Lohkamp, B, Andersen, B, Piskur, J, Dobritzsch, D. | | 登録日 | 2007-11-21 | | 公開日 | 2008-03-25 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | The Crystal Structure of Beta-Alanine Synthase from Drosophila Melanogaster Reveals a Homooctameric Helical Turn-Like Assembly.
J.Mol.Biol., 377, 2008
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1Z6P
 | | Glycogen phosphorylase AMP site inhibitor complex | | 分子名称: | 4-{2-[(3-NITROBENZOYL)AMINO]PHENOXY}PHTHALIC ACID, Glycogen phosphorylase, muscle form | | 著者 | Kristiansen, M, Andersen, B, Iversen, L.F, Westergaard, N. | | 登録日 | 2005-03-23 | | 公開日 | 2005-04-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Identification, synthesis and chracterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site
J.Med.Chem., 47, 2004
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1Z6Q
 | | Glycogen phosphorylase with inhibitor in the AMP site | | 分子名称: | 4-{2,4-BIS[(3-NITROBENZOYL)AMINO]PHENOXY}PHTHALIC ACID, Glycogen phosphorylase, muscle form | | 著者 | Kristiansen, M, Andersen, B, Iversen, L.F, Westergaard, N. | | 登録日 | 2005-03-23 | | 公開日 | 2005-04-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Identification, synthesis and chracterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site
J.Med.Chem., 47, 2004
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8BLA
 | | Human serotonin 5-HT3A receptor in complex with vortioxetine (detergent, ECD only, active/distorted conformation) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ... | | 著者 | Lopez-Sanchez, U, Nury, H. | | 登録日 | 2022-11-09 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors.
Nat.Struct.Mol.Biol., 31, 2024
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8BL8
 | | Human serotonin 5-HT3A receptor (apo, active/distorted conformation) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A | | 著者 | Lopez-Sanchez, U, Nury, H. | | 登録日 | 2022-11-09 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors.
Nat.Struct.Mol.Biol., 31, 2024
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8BLB
 | | Human serotonin 5-HT3A receptor in complex with vortioxetine (nanodiscs, ECD, active/distorted conformation) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ... | | 著者 | Lopez-Sanchez, U, Nury, H. | | 登録日 | 2022-11-09 | | 公開日 | 2024-05-15 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors.
Nat.Struct.Mol.Biol., 31, 2024
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2FTY
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2FVM
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2FVK
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8AW2
 | | Mouse serotonin 5-HT3A receptor in complex with vortioxetine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ... | | 著者 | Lopez-Sanchez, U, Nury, H. | | 登録日 | 2022-08-29 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors.
Nat.Struct.Mol.Biol., 31, 2024
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8AXD
 | | Human serotonin 5-HT3A receptor (apo, resting conformation) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A | | 著者 | Lopez-Sanchez, U, Nury, H. | | 登録日 | 2022-08-31 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | | 主引用文献 | Structural determinants for activity of the antidepressant vortioxetine at human and rodent 5-HT 3 receptors.
Nat.Struct.Mol.Biol., 31, 2024
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2FTW
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1WV0
 | | Crystallographic studies on acyl ureas, a new class of inhibitors of glycogen phosphorylase. Broad specificity of the allosteric site | | 分子名称: | 4-[4-({[(2,4-DICHLOROBENZOYL)AMINO]CARBONYL}AMINO)-2,3-DIMETHYLPHENOXY]BUTANOIC ACID, Glycogen phosphorylase, muscle form, ... | | 著者 | Oikonomakos, N.G, Kosmopoulou, M.N, Chrysina, E.D, Leonidas, D.D, Klabunde, T, Wendt, K.U, Defossa, E. | | 登録日 | 2004-12-10 | | 公開日 | 2005-12-10 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs
Protein Sci., 14, 2005
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1WV1
 | | Crystallographic studies on acyl ureas, a new class of inhibitors of glycogenphosphorylase. Broad specificity of the allosteric site | | 分子名称: | 5-[3-({[(2,4-DICHLOROBENZOYL)AMINO]CARBONYL}AMINO)-2-METHYLPHENOXY]PENTANOIC ACID, Glycogen phosphorylase, muscle form, ... | | 著者 | Oikonomakos, N.G, Kosmopoulou, M.N, Chrysina, E.D, Leonidas, D.D, Klabunde, T, Wendt, K.U, Defossa, E. | | 登録日 | 2004-12-10 | | 公開日 | 2005-12-10 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs
Protein Sci., 14, 2005
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1WUY
 | | Crystallographic studies on acyl ureas, a new class of inhibitors of glycogen phosphorylase. Broad specificity of the allosteric site | | 分子名称: | 4-[3-CHLORO-4-({[(2,4-DICHLOROBENZOYL)AMINO]CARBONYL}AMINO)PHENOXY]BUTANOIC ACID, Glycogen phosphorylase, muscle form, ... | | 著者 | Oikonomakos, N.G, Kosmopoulou, M.N, Chrysina, E.D, Leonidas, D.D, Klabunde, T, Wendt, K.U, Defossa, E. | | 登録日 | 2004-12-09 | | 公開日 | 2005-12-09 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs
Protein Sci., 14, 2005
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1R3N
 | | Crystal structure of beta-alanine synthase from Saccharomyces kluyveri | | 分子名称: | BETA-AMINO ISOBUTYRATE, ZINC ION, beta-alanine synthase | | 著者 | Lundgren, S, Gojkovic, Z, Piskur, J, Dobritzsch, D. | | 登録日 | 2003-10-02 | | 公開日 | 2003-11-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Yeast beta-Alanine Synthase Shares a Structural Scaffold and Origin with Dizinc-dependent Exopeptidases
J.Biol.Chem., 278, 2003
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1R43
 | | Crystal structure of beta-alanine synthase from Saccharomyces kluyveri (selenomethionine substituted protein) | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-AMINO ISOBUTYRATE, ... | | 著者 | Lundgren, S, Gojkovic, Z, Piskur, J, Dobritzsch, D. | | 登録日 | 2003-10-03 | | 公開日 | 2003-11-11 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Yeast beta-Alanine Synthase Shares a Structural Scaffold and Origin with Dizinc-dependent Exopeptidases
J.Biol.Chem., 278
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