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4WGK
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BU of 4wgk by Molmil
Crystal structure of human neutral ceramidase with Zn-bound phosphate
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Airola, M.V, Pulkoski-Gross, M.J, Obeid, L.M, Hannun, Y.A.
登録日2014-09-18
公開日2015-07-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.582 Å)
主引用文献Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase.
Structure, 23, 2015
5UVG
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BU of 5uvg by Molmil
Crystal structure of the human neutral sphingomyelinase 2 (nSMase2) catalytic domain with insertion deleted and calcium bound
分子名称: CALCIUM ION, Sphingomyelin phosphodiesterase 3,Sphingomyelin phosphodiesterase 3
著者Airola, M.V, Guja, K.E, Garcia-Diaz, M, Hannun, Y.A.
登録日2017-02-20
公開日2017-06-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3LNR
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BU of 3lnr by Molmil
Crystal structure of poly-HAMP domains from the P. aeruginosa soluble receptor Aer2
分子名称: Aerotaxis transducer Aer2, CHLORIDE ION
著者Airola, M.V, Bilwes, A.M, Crane, B.R.
登録日2010-02-02
公開日2010-05-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structure of concatenated HAMP domains provides a mechanism for signal transduction.
Structure, 18, 2010
4HI4
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BU of 4hi4 by Molmil
Crystal structure of the 5-coordinate ferric heme-binding PAS domain of Aer2 from P. aeruginosa
分子名称: Aerotaxis transducer Aer2, CHLORIDE ION, GLYCEROL, ...
著者Airola, M.V, Crane, B.R.
登録日2012-10-11
公開日2013-01-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Architecture of the soluble receptor Aer2 indicates an in-line mechanism for PAS and HAMP domain signaling.
J.Mol.Biol., 425, 2013
4I44
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BU of 4i44 by Molmil
Aer2 poly-HAMP domains: V33G HAMP1 inverted signaling mutant
分子名称: Aerotaxis transducer Aer2, CHLORIDE ION
著者Airola, M.V, Sukomon, N, Crane, B.R.
登録日2012-11-27
公開日2013-02-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献HAMP Domain Conformers That Propagate Opposite Signals in Bacterial Chemoreceptors.
Plos Biol., 11, 2013
4I3M
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BU of 4i3m by Molmil
Aer2 poly-HAMP domains: L44H HAMP1 CW-lock mutant
分子名称: Aerotaxis transducer Aer2, CHLORIDE ION, MAGNESIUM ION, ...
著者Airola, M.V, Sukomon, N, Crane, B.R.
登録日2012-11-26
公開日2013-02-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献HAMP Domain Conformers That Propagate Opposite Signals in Bacterial Chemoreceptors.
Plos Biol., 11, 2013
8EXD
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BU of 8exd by Molmil
Crystal structure of Aspergillus fumigatus sterylglucosidase A
分子名称: Sterylglucosidase A (SglA)
著者Pereira de Sa, N, Del Poeta, M, Airola, M.V.
登録日2022-10-25
公開日2023-03-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Targeting Sterylglucosidase A to Treat Aspergillus fumigatus Infections.
Mbio, 14, 2023
8UJL
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BU of 8ujl by Molmil
Crystal structure of human CTDNEP1-NEP1R1 protein phosphatase complex
分子名称: CTD nuclear envelope phosphatase 1,Nuclear envelope phosphatase-regulatory subunit 1
著者Gao, S, Airola, M.V.
登録日2023-10-11
公開日2024-05-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Structure and mechanism of the human CTDNEP1-NEP1R1 membrane protein phosphatase complex necessary to maintain ER membrane morphology.
Proc.Natl.Acad.Sci.USA, 121, 2024
8UJM
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BU of 8ujm by Molmil
Crystal structure of human CTDNEP1-NEP1R1 protein phosphatase complex with magnesium
分子名称: CTD nuclear envelope phosphatase 1,Nuclear envelope phosphatase-regulatory subunit 1, MAGNESIUM ION
著者Gao, S, Airola, M.V.
登録日2023-10-11
公開日2024-05-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.161 Å)
主引用文献Structure and mechanism of the human CTDNEP1-NEP1R1 membrane protein phosphatase complex necessary to maintain ER membrane morphology.
Proc.Natl.Acad.Sci.USA, 121, 2024
7KIL
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BU of 7kil by Molmil
Crystal structure of the mouse lipin-1 M-Lip domain with zinc
分子名称: CHLORIDE ION, Isoform 2 of Phosphatidate phosphatase LPIN1, ZINC ION
著者Gu, W, Airola, M.V.
登録日2020-10-23
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献The middle lipin domain adopts a membrane-binding dimeric protein fold.
Nat Commun, 12, 2021
7KIH
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BU of 7kih by Molmil
Crystal structure of the mouse lipin-1 M-Lip domain
分子名称: Isoform 2 of Phosphatidate phosphatase LPIN1
著者Gu, W, Airola, M.V.
登録日2020-10-23
公開日2021-07-07
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.467 Å)
主引用文献The middle lipin domain adopts a membrane-binding dimeric protein fold.
Nat Commun, 12, 2021
7KIQ
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BU of 7kiq by Molmil
Crystal structure of the mouse lipin-2 M-Lip domain
分子名称: CALCIUM ION, Phosphatidate phosphatase LPIN2
著者Yang, J.W, Gu, W, Airola, M.V.
登録日2020-10-24
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.523 Å)
主引用文献The middle lipin domain adopts a membrane-binding dimeric protein fold.
Nat Commun, 12, 2021
6TZZ
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BU of 6tzz by Molmil
Crystal Structure of Tetrahymena Thermophila Lipin Phosphatidic Acid Phosphatase with Magnesium
分子名称: MAGNESIUM ION, Nuclear elongation and deformation protein
著者Khayyo, V.I, Airola, M.V.
登録日2019-08-13
公開日2020-03-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a lipin/Pah phosphatidic acid phosphatase
Nat Commun, 11, 2020
6TZY
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BU of 6tzy by Molmil
Crystal Structure of a lipin/Pah Phosphatidic Acid Phosphatase
分子名称: CALCIUM ION, Nuclear elongation and deformation protein
著者Khayyo, V.I, Airola, M.V.
登録日2019-08-13
公開日2020-03-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal Structure of a lipin/Pah Phosphatidic Acid Phosphatase
Nat Commun, 11, 2020
6U8Z
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BU of 6u8z by Molmil
Crystal Structure of Catalytic Domain of Human Phospholipase D1
分子名称: PHOSPHITE ION, Phospholipase D1,Phospholipase D1
著者Bowling, F.Z, Airola, M.V.
登録日2019-09-06
公開日2020-03-18
最終更新日2020-04-01
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Crystal structure of human PLD1 provides insight into activation by PI(4,5)P2and RhoA.
Nat.Chem.Biol., 16, 2020
7LPO
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BU of 7lpo by Molmil
Crystal structure of Cryptococcus neoformans sterylglucosidase 1 with tris
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cytoplasmic protein, MAGNESIUM ION
著者Pereira de Sa, N, Del Poeta, M, Airola, M.V.
登録日2021-02-12
公開日2021-09-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents.
Nat Commun, 12, 2021
7LPQ
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BU of 7lpq by Molmil
Crystal structure of Cryptococcus neoformans sterylglucosidase 1 with hit 9
分子名称: Cytoplasmic protein, GLYCEROL, MAGNESIUM ION, ...
著者Pereira de Sa, N, Del Poeta, M, Airola, M.V.
登録日2021-02-12
公開日2021-09-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents.
Nat Commun, 12, 2021
7LPP
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BU of 7lpp by Molmil
Crystal structure of Cryptococcus neoformans sterylglucosidase 1 with hit 1
分子名称: 4-(hydroxymethyl)-1-[[2-(3-methoxyphenyl)-1,3-thiazol-5-yl]methyl]piperidin-4-ol, Cytoplasmic protein, GLYCEROL, ...
著者Pereira de Sa, N, Del Poeta, M, Airola, M.V.
登録日2021-02-12
公開日2021-09-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents.
Nat Commun, 12, 2021
7LHK
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BU of 7lhk by Molmil
High-Resolution Crystal Structure of a Lipin/Pah Phosphatidic Acid Phosphatase
分子名称: CACODYLATE ION, Nuclear elongation and deformation protein
著者Khayyo, V.I, Airola, M.V.
登録日2021-01-25
公開日2022-02-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献High-resolution structure of phosphatidic acid phosphohydrolase from Tetrahymena thermophila
To be published

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件を2024-09-11に公開中

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