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6MSH
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Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-11-21
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
6VYO
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BU of 6vyo by Molmil
Crystal structure of RNA binding domain of nucleocapsid phosphoprotein from SARS coronavirus 2
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ...
著者Chang, C, Michalska, K, Jedrzejczak, R, Maltseva, N, Endres, M, Godzik, A, Kim, Y, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-02-27
公開日2020-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Iscience, 27, 2024
8K0R
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BU of 8k0r by Molmil
The Anoxybacillus pushchinoensis ORF-less Group IIC Intron HYER1 at symmetric post cleavge state
分子名称: DNA, MAGNESIUM ION, RNA (542-MER)
著者Zhu, H.Z, Liu, J.J.G.
登録日2023-07-10
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Hydrolytic endonucleolytic ribozyme (HYER) is programmable for sequence-specific DNA cleavage.
Science, 383, 2024
8K15
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BU of 8k15 by Molmil
The Streptococcus azizii ORF-less Group IIC intron HYER2 at apo state
分子名称: MAGNESIUM ION, RNA (470-MER)
著者Zhu, H.Z, Liu, J.J.G.
登録日2023-07-10
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Hydrolytic endonucleolytic ribozyme (HYER) is programmable for sequence-specific DNA cleavage.
Science, 383, 2024
8RJX
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BU of 8rjx by Molmil
Solution structure of osmoregulator OsmY from E. coli.
分子名称: Osmotically-inducible protein Y
著者Iyer, A, Luo, Y, le Paige, U.B.A, van Ingen, H.
登録日2023-12-22
公開日2024-07-03
最終更新日2024-07-17
実験手法SOLUTION NMR
主引用文献The Structure and Function of the Bacterial Osmotically Inducible Protein Y.
J.Mol.Biol., 436, 2024
7XMZ
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BU of 7xmz by Molmil
Cryo-EM structure of SARS-CoV-2 spike glycoprotein in complex with three D2 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, D2 heavy chain, D2 light chain, ...
著者Wang, X, Li, X.
登録日2022-04-27
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.
Cell Discov, 8, 2022
7XMX
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BU of 7xmx by Molmil
Cryo-EM structure of SARS-CoV-2 spike glycoprotein in complex with three F61 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, F61 heavy chain, F61 light chain, ...
著者Wang, X, Li, X.
登録日2022-04-27
公開日2022-11-23
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structural basis of a two-antibody cocktail exhibiting highly potent and broadly neutralizing activities against SARS-CoV-2 variants including diverse Omicron sublineages.
Cell Discov, 8, 2022
6MSE
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BU of 6mse by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-11-21
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
6MSB
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BU of 6msb by Molmil
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Mao, Y.D.
登録日2018-10-16
公開日2018-12-05
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.
Nature, 565, 2019
8KHD
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BU of 8khd by Molmil
The interface structure of Omicron RBD binding to 5817 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 5817, Light chain of 5817, ...
著者Cao, L, Wang, X.
登録日2023-08-21
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain.
Cell Rep, 43, 2024
8KHC
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BU of 8khc by Molmil
SARS-CoV-2 Omicron spike in complex with 5817 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 5817 Fab, ...
著者Cao, L, Wang, X.
登録日2023-08-21
公開日2024-04-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain.
Cell Rep, 43, 2024
8K0S
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BU of 8k0s by Molmil
The Anoxybacillus pushchinoensis ORF-less Group IIC Intron HYER1 with 10-nt TRS at symmetric apo state
分子名称: MAGNESIUM ION, RNA (543-MER)
著者Zhu, H.Z, Liu, J.J.G.
登録日2023-07-10
公開日2024-05-01
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Hydrolytic endonucleolytic ribozyme (HYER) is programmable for sequence-specific DNA cleavage.
Science, 383, 2024
8K0Q
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BU of 8k0q by Molmil
The Anoxybacillus pushchinoensis ORF-less Group IIC Intron HYER1 at symmetric pre-cleavage state
分子名称: DNA, MAGNESIUM ION, RNA (542-MER)
著者Zhu, H.Z, Liu, J.J.G.
登録日2023-07-10
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Hydrolytic endonucleolytic ribozyme (HYER) is programmable for sequence-specific DNA cleavage.
Science, 383, 2024
8K0P
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BU of 8k0p by Molmil
The Anoxybacillus pushchinoensis ORF-less Group IIC Intron HYER1 at symmetric apo state
分子名称: MAGNESIUM ION, RNA (542-MER)
著者Zhu, H.Z, Liu, J.J.G.
登録日2023-07-10
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Hydrolytic endonucleolytic ribozyme (HYER) is programmable for sequence-specific DNA cleavage.
Science, 383, 2024
6VQ2
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BU of 6vq2 by Molmil
HLA-B*27:05 presenting an HIV-1 14mer peptide
分子名称: 14-mer peptide, Beta-2-microglobulin, GLYCEROL, ...
著者Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N.
登録日2020-02-04
公開日2021-02-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
6VQD
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BU of 6vqd by Molmil
HLA-B*27:05 presenting an HIV-1 8mer peptide
分子名称: 8-mer peptide, Beta-2-microglobulin, GLYCEROL, ...
著者Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N.
登録日2020-02-05
公開日2021-02-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
6VQE
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BU of 6vqe by Molmil
HLA-B*27:05 presenting an HIV-1 13mer peptide
分子名称: 13-mer peptide, Beta-2-microglobulin, GLYCEROL, ...
著者Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N.
登録日2020-02-05
公開日2021-02-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
6VQY
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BU of 6vqy by Molmil
HLA-B*27:05 presenting an HIV-1 7mer peptide
分子名称: 7-mer peptide, ARGININE, Beta-2-microglobulin, ...
著者Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N.
登録日2020-02-06
公開日2021-02-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
6VQZ
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BU of 6vqz by Molmil
HLA-B*27:05 presenting an HIV-1 6mer peptide
分子名称: 6-mer peptide, ARGININE, Beta-2-microglobulin, ...
著者Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N.
登録日2020-02-06
公開日2021-02-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
6VPZ
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BU of 6vpz by Molmil
HLA-B*27:05 presenting an HIV-1 11mer peptide
分子名称: 11-mer peptide, Beta-2-microglobulin, GLYCEROL, ...
著者Pymm, P, Tenzer, S, Wee, E, Weimershaus, M, Burgevin, A, Kollnberger, S, Gerstoft, J, Josephs, T.M, Ladell, K, Mclaren, J.E, Appay, V, Price, D.A, Fugger, L, Bell, J.I, Hansjorg, S, Van Endert, P, Harkiolaki, M, Iversen, A.K.N.
登録日2020-02-04
公開日2021-02-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Epitope length variants balance protective immune responses and viral escape in HIV-1 infection
Cell Rep, 38, 2022
8JEY
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BU of 8jey by Molmil
Cryo-EM structure of alpha-synuclein pS87 fibril
分子名称: Alpha-synuclein
著者Xia, W.C, Sun, Y.P, Liu, C.
登録日2023-05-16
公開日2024-04-17
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Phosphorylation and O-GlcNAcylation at the same alpha-synuclein site generate distinct fibril structures.
Nat Commun, 15, 2024
4X1I
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BU of 4x1i by Molmil
Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications
分子名称: 2-methyl-L-alanyl-N-[(3R,4S,5S)-3-methoxy-1-{(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-{[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino}propyl]pyrrolidin-1-yl}-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Parris, K.D.
登録日2014-11-24
公開日2015-03-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications.
J.Med.Chem., 57, 2014
6LN4
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Estrogen-related receptor beta(ERR2) in complex with PGC1a-2a
分子名称: 10-mer from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, Steroid hormone receptor ERR2
著者Yao, B.Q, Li, Y.
登録日2019-12-28
公開日2020-10-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural Insights into the Specificity of Ligand Binding and Coactivator Assembly by Estrogen-Related Receptor beta.
J.Mol.Biol., 432, 2020
4X1Y
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BU of 4x1y by Molmil
Discovery of cytotoxic Dolastatin 10 analogs with N-terminal modifications
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Parris, K.D.
登録日2014-11-25
公開日2015-03-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications.
J.Med.Chem., 57, 2014
8J1H
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BU of 8j1h by Molmil
Agonist1 and Ruthenium Red bound state of mTRPV4
分子名称: 8-fluoranyl-3-[4-(4-fluoranylphenoxy)phenyl]-2-(4-methylpiperazin-1-yl)quinazolin-4-one, Transient receptor potential cation channel subfamily V member 4
著者Zhen, W.X, Yang, F.
登録日2023-04-12
公開日2023-08-09
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.88 Å)
主引用文献Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel.
Cell Discov, 9, 2023

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