3MP1
| Complex structure of Sgf29 and trimethylated H3K4 | 分子名称: | ACETATE ION, H3K4me3 peptide, Maltose-binding periplasmic protein,LINKER,SAGA-associated factor 29, ... | 著者 | Li, J, Ruan, J, Wu, M, Xue, X, Zang, J. | 登録日 | 2010-04-24 | 公開日 | 2011-05-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation Embo J., 30, 2011
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4BBF
| Aminoalkylpyrimidine Inhibitor Complexes with JAK2 | 分子名称: | (2R)-N-[4-[2-[(4-morpholin-4-ylphenyl)amino]pyrimidin-4-yl]phenyl]pyrrolidine-2-carboxamide, TYROSINE-PROTEIN KINASE JAK2 | 著者 | Li, J. | 登録日 | 2012-09-21 | 公開日 | 2012-11-21 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Sar and in Vivo Evaluation of 4-Aryl-2-Aminoalkylpyrimidines as Potent and Selective Janus Kinase 2 (Jak2) Inhibitors Bioorg.Med.Chem.Lett., 22, 2012
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1DLC
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8IU2
| Cryo-EM structure of Long-wave-sensitive opsin 1 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Peng, Q, Cheng, X.Y, Li, J, Lu, Q.Y, Li, Y.Y, Zhang, J. | 登録日 | 2023-03-23 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Cryo-EM structure of Long-wave-sensitive opsin 1 To Be Published
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5YTK
| Crystal structure of SIRT3 bound to a leucylated AceCS2 | 分子名称: | AceCS2-KLeu, LEUCINE, LYSINE, ... | 著者 | Li, J, Gong, W, Xu, Y. | 登録日 | 2017-11-18 | 公開日 | 2017-12-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations Cell Metab., 27, 2018
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2FJ3
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5HC2
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5HC0
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5HC3
| The structure of esterase Est22 | 分子名称: | GLYCEROL, Lipolytic enzyme | 著者 | Li, J, Huang, J. | 登録日 | 2016-01-04 | 公開日 | 2017-01-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural insights of a hormone sensitive lipase homologue Est22. Sci Rep, 6, 2016
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5HC5
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5HC4
| Structure of esterase Est22 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Lipolytic enzyme | 著者 | Li, J, Huang, J. | 登録日 | 2016-01-04 | 公開日 | 2017-01-18 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural insights of a hormone sensitive lipase homologue Est22. Sci Rep, 6, 2016
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4R3M
| Crystal structure of Human Hsp90 with JR9 | 分子名称: | Heat shock protein HSP 90-alpha, N~3~-benzyl-2-[(6-bromo-1,3-benzodioxol-5-yl)methyl]imidazo[1,2-a]pyrazine-3,8-diamine | 著者 | Li, J, Yang, M, Ren, J, Xiong, B, He, J. | 登録日 | 2014-08-16 | 公開日 | 2014-11-05 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Multi-substituted 8-aminoimidazo[1,2-a]pyrazines by Groebke-Blackburn-Bienayme reaction and their Hsp90 inhibitory activity. Org.Biomol.Chem., 13, 2015
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6CMX
| Human Teneurin 2 extra-cellular region | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Teneurin-2, alpha-D-mannopyranose, ... | 著者 | Shalev-Benami, M, Li, J, Sudhof, T, Skiniotis, G, Arac, D. | 登録日 | 2018-03-06 | 公開日 | 2018-07-25 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural Basis for Teneurin Function in Circuit-Wiring: A Toxin Motif at the Synapse. Cell, 173, 2018
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4LWH
| Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ5 | 分子名称: | Heat shock protein HSP 90-alpha, N-{3-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazol-5-yl}cyclopropanecarboxamide | 著者 | Li, J, Shi, F, Xiong, B, He, J. | 登録日 | 2013-07-27 | 公開日 | 2014-07-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors. Eur.J.Med.Chem., 87, 2014
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4LWG
| Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ4 | 分子名称: | 1-(5-chloro-2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone, Heat shock protein HSP 90-alpha | 著者 | Li, J, Shi, F, Xiong, B, He, J. | 登録日 | 2013-07-27 | 公開日 | 2014-07-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | 主引用文献 | Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors. Eur.J.Med.Chem., 87, 2014
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4LWE
| Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ2 | 分子名称: | Heat shock protein HSP 90-alpha, N-[3-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)-1,2-oxazol-5-yl]acetamide | 著者 | Li, J, Shi, F, Xiong, B, He, J. | 登録日 | 2013-07-27 | 公開日 | 2014-07-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors. Eur.J.Med.Chem., 87, 2014
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4LWF
| Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ3 | 分子名称: | 4-(5-amino-1,2-oxazol-3-yl)-6-(propan-2-yl)benzene-1,3-diol, Heat shock protein HSP 90-alpha | 著者 | Li, J, Shi, F, Xiong, B, He, J. | 登録日 | 2013-07-27 | 公開日 | 2014-07-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors. Eur.J.Med.Chem., 87, 2014
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4LWI
| Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ6 | 分子名称: | Heat shock protein HSP 90-alpha, N-{3-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-(4-methoxyphenyl)-1,2-oxazol-5-yl}cyclopropanecarboxamide | 著者 | Li, J, Shi, F, Xiong, B, He, J. | 登録日 | 2013-07-27 | 公開日 | 2014-07-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors. Eur.J.Med.Chem., 87, 2014
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2JOM
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4RLW
| Crystal Structure of (3R)-hydroxyacyl-ACP dehydratase HadAB hetero-dimer from Mycobacterium tuberculosis complexed with Butein | 分子名称: | (2E)-1-(2,4-dihydroxyphenyl)-3-(3,4-dihydroxyphenyl)prop-2-en-1-one, (3R)-hydroxyacyl-ACP dehydratase subunit HadA, (3R)-hydroxyacyl-ACP dehydratase subunit HadB, ... | 著者 | Li, J, Dong, Y, Rao, Z.H. | 登録日 | 2014-10-18 | 公開日 | 2015-10-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.196 Å) | 主引用文献 | Molecular basis for the inhibition of beta-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors. Protein Cell, 6, 2015
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2FCO
| Crystal Structure of Bacillus stearothermophilus PrfA-Holliday Junction Resolvase | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, recombination protein U (penicillin-binding protein related factor A) | 著者 | Li, J, Jedrzejas, M.J. | 登録日 | 2005-12-12 | 公開日 | 2006-11-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure, flexibility, and mechanism of the Bacillus stearothermophilus RecU Holliday junction resolvase. Proteins, 68, 2007
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2L26
| Rv0899 from Mycobacterium tuberculosis contains two separated domains | 分子名称: | Uncharacterized protein Rv0899/MT0922 | 著者 | Shi, C, Li, J, Gao, Y, Wu, K, Huang, H, Tian, C. | 登録日 | 2010-08-12 | 公開日 | 2011-08-17 | 最終更新日 | 2011-12-07 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Studies of Mycobacterium tuberculosis Rv0899 Reveal a Monomeric Membrane-Anchoring Protein with Two Separate Domains J.Mol.Biol., 2011
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6JLS
| Crystal Structure of FMN-dependent Cysteine Decarboxylases TvaF from Thioviridamide Biosynthesis | 分子名称: | FLAVIN MONONUCLEOTIDE, Putative flavoprotein decarboxylase | 著者 | Li, J, Lu, J, Wang, H, Zhu, J. | 登録日 | 2019-03-06 | 公開日 | 2019-06-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Characterization of the FMN-Dependent Cysteine Decarboxylase from Thioviridamide Biosynthesis. Org.Lett., 21, 2019
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5ZCK
| Structure of the RIP3 core region | 分子名称: | SODIUM ION, peptide from Receptor-interacting serine/threonine-protein kinase 3 | 著者 | Li, J, Wu, H. | 登録日 | 2018-02-18 | 公開日 | 2018-04-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.271 Å) | 主引用文献 | The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex. Cell, 173, 2018
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3COX
| CRYSTAL STRUCTURE OF CHOLESTEROL OXIDASE COMPLEXED WITH A STEROID SUBSTRATE. IMPLICATIONS FOR FAD DEPENDENT ALCOHOL OXIDASES | 分子名称: | CHOLESTEROL OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Vrielink, A, Li, J, Brick, P, Blow, D.M. | 登録日 | 1993-06-14 | 公開日 | 1993-10-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of cholesterol oxidase complexed with a steroid substrate: implications for flavin adenine dinucleotide dependent alcohol oxidases. Biochemistry, 32, 1993
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