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7X2T
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BU of 7x2t by Molmil
Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 8A10 (CVB1-M:8A10)
分子名称: 8A10 heavy chain, 8A10 light chain, Capsid protein VP4, ...
著者Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N.
登録日2022-02-26
公開日2022-09-28
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.
Cell Host Microbe, 30, 2022
7X37
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BU of 7x37 by Molmil
Cryo-EM structure of Coxsackievirus B1 A particle in complex with nAb 2E6 (CVB1-A:2E6)
分子名称: 2E6 heavy chain, 2E6 light chain, VP2, ...
著者Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N.
登録日2022-02-28
公開日2022-09-28
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.31 Å)
主引用文献Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.
Cell Host Microbe, 30, 2022
7X3E
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BU of 7x3e by Molmil
Cryo-EM structure of Coxsackievirus B1 pre-A-particle in complex with nAb 9A3 (CVB1-pre-A:9A3)
分子名称: 9A3 heavy chain, 9A3 light chain, Capsid protein VP4, ...
著者Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N.
登録日2022-02-28
公開日2022-09-28
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.
Cell Host Microbe, 30, 2022
7X4K
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BU of 7x4k by Molmil
Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (classified from CVB1 mature virion in complex with 8A10 and 9A3)
分子名称: 9A3 heavy chain, 9A3 light chain, Genome polyprotein, ...
著者Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N.
登録日2022-03-02
公開日2022-09-28
最終更新日2025-06-18
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.
Cell Host Microbe, 30, 2022
7X3D
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BU of 7x3d by Molmil
Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 9A3 (CVB1-M:9A3)
分子名称: 9A3 heavy chain, 9A3 light chain, Capsid protein VP4, ...
著者Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N.
登録日2022-02-28
公開日2022-09-28
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.
Cell Host Microbe, 30, 2022
7X40
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BU of 7x40 by Molmil
Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 8A10 (classified from CVB1 mature virion in complex with 8A10 and 2E6)
分子名称: 8A10 heavy chain, 8A10 light chain, Capsid protein VP4, ...
著者Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N.
登録日2022-03-01
公開日2022-09-28
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.
Cell Host Microbe, 30, 2022
7X46
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BU of 7x46 by Molmil
Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 2E6 (classified from CVB1 mature virion in complex with 8A10 and 2E6)
分子名称: 2E6 heavy chain, 2E6 light chain, VP2, ...
著者Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N.
登録日2022-03-02
公開日2022-09-28
最終更新日2025-06-18
実験手法ELECTRON MICROSCOPY (3.85 Å)
主引用文献Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.
Cell Host Microbe, 30, 2022
7X47
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BU of 7x47 by Molmil
Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 2E6 (classified from CVB1 mature virion in complex with 8A10 and 2E6)
分子名称: 2E6 heavy chain, 2E6 light chain, Genome polyprotein, ...
著者Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N.
登録日2022-03-02
公開日2022-09-28
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.
Cell Host Microbe, 30, 2022
7X4M
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BU of 7x4m by Molmil
Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 8A10 (classified from CVB1 mature virion in complex with 8A10, 2E6 and 9A3)
分子名称: 8A10 heavy chain, 8A10 light chain, Capsid protein VP4, ...
著者Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N.
登録日2022-03-02
公開日2022-09-28
最終更新日2025-06-18
実験手法ELECTRON MICROSCOPY (3.34 Å)
主引用文献Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.
Cell Host Microbe, 30, 2022
4ES2
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BU of 4es2 by Molmil
Double-stranded Endonuclease Activity in B. halodurans Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Cas2 Protein
分子名称: BH0342 protein
著者Ke, A, Nam, K.H.
登録日2012-04-21
公開日2012-08-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.299 Å)
主引用文献Double-stranded endonuclease activity in Bacillus halodurans clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas2 protein.
J. Biol. Chem., 287, 2012
4ES3
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BU of 4es3 by Molmil
Double-stranded Endonuclease Activity in B. halodurans Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Cas2 Protein
分子名称: 1,2-ETHANEDIOL, BH0342 protein
著者Ke, A, Nam, K.H.
登録日2012-04-21
公開日2012-08-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.704 Å)
主引用文献Double-stranded endonuclease activity in Bacillus halodurans clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas2 protein.
J. Biol. Chem., 287, 2012
7X3Y
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BU of 7x3y by Molmil
Cryo-EM structure of Coxsackievirus B1 empty particle in complex with nAb 9A3 (CVB1-E:9A3)
分子名称: 9A3 heavy chain, 9A3 light chain, VP2, ...
著者Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N.
登録日2022-03-01
公開日2023-06-07
最終更新日2025-06-25
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.
Cell Host Microbe, 30, 2022
7X35
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BU of 7x35 by Molmil
Cryo-EM structure of Coxsackievirus B1 A-particle in complex with nAb 8A10 (CVB1-A:8A10)
分子名称: 8A10 heavy chain, 8A10 light chain, VP2, ...
著者Zheng, Q, Zhu, R, Sun, H, Cheng, T, Li, S, Xia, N.
登録日2022-02-28
公開日2024-07-24
最終更新日2025-06-18
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.
Cell Host Microbe, 30, 2022
6NE7
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BU of 6ne7 by Molmil
Structure of G810A mutant of RET protein tyrosine kinase domain.
分子名称: ADENOSINE MONOPHOSPHATE, FORMIC ACID, Proto-oncogene tyrosine-protein kinase receptor Ret
著者Terzyan, S.S, Shen, T, Wu, J, Mooers, B.H.M.
登録日2018-12-17
公開日2019-06-05
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural basis of resistance of mutant RET protein-tyrosine kinase to its inhibitors nintedanib and vandetanib.
J.Biol.Chem., 294, 2019
6NEC
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BU of 6nec by Molmil
STRUCTURE OF RET PROTEIN TYROSINE KINASE DOMAIN IN COMPLEX WITH NINTEDANIB
分子名称: FORMIC ACID, Proto-oncogene tyrosine-protein kinase receptor Ret, methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
著者Terzyan, S.S, Shen, T, Wu, J, Mooers, B.H.M.
登録日2018-12-17
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural basis of resistance of mutant RET protein-tyrosine kinase to its inhibitors nintedanib and vandetanib.
J.Biol.Chem., 294, 2019
6NJA
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BU of 6nja by Molmil
Structure of WT RET protein tyrosine kinase domain at 1.92A resolution.
分子名称: ADENINE, FORMIC ACID, Proto-oncogene tyrosine-protein kinase receptor Ret
著者Terzyan, S.S, Shen, T, Wu, J, Mooers, B.H.M.
登録日2019-01-02
公開日2019-06-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Structural basis of resistance of mutant RET protein-tyrosine kinase to its inhibitors nintedanib and vandetanib.
J.Biol.Chem., 294, 2019
6OLU
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BU of 6olu by Molmil
RIAM RA-PH core structure in the P212121 space group
分子名称: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
著者Wu, J.
登録日2019-04-17
公開日2020-04-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Phosphorylation of RIAM by src promotes integrin activation by unmasking the PH domain of RIAM.
Structure, 29, 2021
6O6H
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BU of 6o6h by Molmil
RIAM cc-RA-PH structure in the P21212 space group
分子名称: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
著者Wu, J.
登録日2019-03-06
公開日2020-09-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Phosphorylation of RIAM by Src Promotes Integrin Activation by Unmasking the PH Domain of RIAM.
Structure, 2020
5W2J
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BU of 5w2j by Molmil
Crystal structure of dimeric form of mouse Glutaminase C
分子名称: CHLORIDE ION, Glutaminase kidney isoform, mitochondrial, ...
著者Cerione, R.A, Li, Y.
登録日2017-06-06
公開日2018-10-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanistic Basis of Glutaminase Activation: A KEY ENZYME THAT PROMOTES GLUTAMINE METABOLISM IN CANCER CELLS.
J. Biol. Chem., 291, 2016
4H7A
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BU of 4h7a by Molmil
Crystal structure of CasB from Thermus thermophilus
分子名称: CRISPR-associated protein Cse2
著者Ke, A, Nam, K.H.
登録日2012-09-20
公開日2012-10-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Nucleic acid binding surface and dimer interface revealed by CRISPR-associated CasB protein structures.
Febs Lett., 586, 2012
5IC0
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BU of 5ic0 by Molmil
Structural analysis of a talin triple domain module
分子名称: 1,2-ETHANEDIOL, Talin-1
著者Wu, J, Chang, Y.-C.E, Zhang, H, Brennan, M.L.
登録日2016-02-22
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural and Functional Analysis of a Talin Triple-Domain Module Suggests an Alternative Talin Autoinhibitory Configuration.
Structure, 24, 2016
4H79
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BU of 4h79 by Molmil
Crystal structure of CasB from Thermobifida fusca
分子名称: 1,2-ETHANEDIOL, CRISPR-associated protein, Cse2 family
著者Ke, A, Nam, K.H.
登録日2012-09-20
公開日2012-10-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Nucleic acid binding surface and dimer interface revealed by CRISPR-associated CasB protein structures.
Febs Lett., 586, 2012
6KHY
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BU of 6khy by Molmil
The crystal structure of AsfvAP:AG
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (AGCGTCACCGACGAGGC), DNA(AGCGTCACCGACGAGG), ...
著者Chen, Y.Q, Gan, J.H.
登録日2019-07-16
公開日2020-06-03
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.008 Å)
主引用文献A unique DNA-binding mode of African swine fever virus AP endonuclease.
Cell Discov, 6, 2020
7E9O
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BU of 7e9o by Molmil
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(3 up RBDs, state2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ...
著者Wang, X.F, Zhu, Y.Q.
登録日2021-03-04
公開日2022-03-09
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022
7E9Q
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BU of 7e9q by Molmil
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 out RBD, state3)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ...
著者Wang, X.F, Zhu, Y.Q.
登録日2021-03-04
公開日2022-03-09
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.65 Å)
主引用文献A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022

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件を2025-07-09に公開中

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