2NQJ
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![BU of 2nqj by Molmil](/molmil-images/mine/2nqj) | Crystal structure of Escherichia coli endonuclease IV (Endo IV) E261Q mutant bound to damaged DNA | 分子名称: | 5'-D(*CP*GP*TP*CP*GP*TP*CP*GP*GP*GP*GP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*CP*CP*(3DR)P*CP*GP*AP*CP*GP*AP*CP*G)-3', Endonuclease 4, ... | 著者 | Garcin-Hosfield, E.D, Hosfield, D.J, Tainer, J.A. | 登録日 | 2006-10-31 | 公開日 | 2007-11-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | DNA apurinic-apyrimidinic site binding and excision by endonuclease IV. Nat.Struct.Mol.Biol., 15, 2008
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2NQ9
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![BU of 2nq9 by Molmil](/molmil-images/mine/2nq9) | High resolution crystal structure of Escherichia coli endonuclease IV (Endo IV) Y72A mutant bound to damaged DNA | 分子名称: | 5'-D(*AP*TP*AP*TP*CP*T)-3', 5'-D(*AP*TP*CP*TP*GP*AP*AP*GP*TP*AP*T)-3', 5'-D(P*(3DR)P*AP*GP*AP*T)-3', ... | 著者 | Garcin-Hosfield, E.D, Hosfield, D.J, Tainer, J.A. | 登録日 | 2006-10-30 | 公開日 | 2007-11-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | DNA apurinic-apyrimidinic site binding and excision by endonuclease IV. Nat.Struct.Mol.Biol., 15, 2008
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3QKS
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![BU of 3qks by Molmil](/molmil-images/mine/3qks) | Mre11 Rad50 binding domain bound to Rad50 | 分子名称: | DNA double-strand break repair protein mre11, DNA double-strand break repair rad50 ATPase | 著者 | Williams, G.J, Williams, R.S, Arvai, A, Moncalian, G, Tainer, J.A. | 登録日 | 2011-02-01 | 公開日 | 2011-03-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair. Nat.Struct.Mol.Biol., 18, 2011
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1M9J
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![BU of 1m9j by Molmil](/molmil-images/mine/1m9j) | human endothelial nitric oxide synthase with chlorzoxazone bound | 分子名称: | CHLORZOXAZONE, PROTOPORPHYRIN IX CONTAINING FE, ZINC ION, ... | 著者 | Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. | 登録日 | 2002-07-29 | 公開日 | 2002-08-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
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2R27
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![BU of 2r27 by Molmil](/molmil-images/mine/2r27) | Constitutively zinc-deficient mutant of human superoxide dismutase (SOD), C6A, H80S, H83S, C111S | 分子名称: | COPPER (II) ION, Superoxide dismutase [Cu-Zn] | 著者 | Roberts, B.R, Getzoff, E.D, Karplus, P.A, Beckman, J.S, Tainer, J.A. | 登録日 | 2007-08-24 | 公開日 | 2007-12-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS. J.Mol.Biol., 373, 2007
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2QT2
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![BU of 2qt2 by Molmil](/molmil-images/mine/2qt2) | Cyclized-Dehydrated Intermediate of GFP Variant Q183E in Chromophore Maturation | 分子名称: | 1,2-ETHANEDIOL, Green fluorescent protein | 著者 | Wood, T.I, Barondeau, D.P, Hitomi, C, Tainer, J.A, Getzoff, E.D. | 登録日 | 2007-07-31 | 公開日 | 2009-04-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Kinetically Isolated Reaction Intermediates Provide Structural Characterization of the Green Fluorescence Protein Fluorophore Biosynthesis Pathway To be Published
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1M8I
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![BU of 1m8i by Molmil](/molmil-images/mine/1m8i) | inducible nitric oxide synthase with 5-nitroindazole bound | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 5-NITROINDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. | 登録日 | 2002-07-24 | 公開日 | 2002-08-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
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1M8E
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![BU of 1m8e by Molmil](/molmil-images/mine/1m8e) | inducible nitric oxide synthase with 7-nitroindazole bound | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 7-NITROINDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. | 登録日 | 2002-07-24 | 公開日 | 2002-08-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
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1M9M
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![BU of 1m9m by Molmil](/molmil-images/mine/1m9m) | human endothelial nitric oxide synthase with 6-nitroindazole bound | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 6-NITROINDAZOLE, ISOPROPYL ALCOHOL, ... | 著者 | Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. | 登録日 | 2002-07-29 | 公開日 | 2002-08-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
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3QKT
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![BU of 3qkt by Molmil](/molmil-images/mine/3qkt) | Rad50 ABC-ATPase with adjacent coiled-coil region in complex with AMP-PNP | 分子名称: | DNA double-strand break repair rad50 ATPase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Williams, G.J, Williams, R.S, Arvai, A, Moncalian, G, Tainer, J.A. | 登録日 | 2011-02-01 | 公開日 | 2011-03-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair. Nat.Struct.Mol.Biol., 18, 2011
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1M8H
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![BU of 1m8h by Molmil](/molmil-images/mine/1m8h) | inducible nitric oxide synthase with 6-nitroindazole bound | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-NITROINDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. | 登録日 | 2002-07-24 | 公開日 | 2002-08-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
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1M9K
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![BU of 1m9k by Molmil](/molmil-images/mine/1m9k) | Human Endothelial Nitric Oxide Synthase with 7-Nitroindazole Bound | 分子名称: | 7-NITROINDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, ZINC ION, ... | 著者 | Rosenfeld, R.J, Garcin, E.D, Panda, K, Andersson, G, Aberg, A, Wallace, A.V, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. | 登録日 | 2002-07-29 | 公開日 | 2002-08-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41, 2002
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2QRF
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![BU of 2qrf by Molmil](/molmil-images/mine/2qrf) | Green Fluorescent Protein: Cyclized-only Intermediate of Chromophore Maturation in the Q183E variant | 分子名称: | 1,2-ETHANEDIOL, Green fluorescent protein, MAGNESIUM ION | 著者 | Wood, T.I, Barondeau, D.P, Hitomi, C, Tainer, J.A, Getzoff, E.D. | 登録日 | 2007-07-28 | 公開日 | 2009-04-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Green Fluorescent Protein Chromophore - Cyclized Intermediate To be Published
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1M9A
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![BU of 1m9a by Molmil](/molmil-images/mine/1m9a) | Crystal structure of the 26 kDa glutathione S-transferase from Schistosoma japonicum complexed with S-hexylglutathione | 分子名称: | Glutathione S-Transferase 26 kDa, S-HEXYLGLUTATHIONE | 著者 | Cardoso, R.M.F, Daniels, D.S, Bruns, C.M, Tainer, J.A. | 登録日 | 2002-07-28 | 公開日 | 2003-03-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Characterization of the electrophile
binding site and substrate binding
mode of the 26-kDa glutathione
S-transferase from Schistosoma
japonicum PROTEINS: STRUCT.,FUNCT.,GENET., 51, 2003
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2NQH
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![BU of 2nqh by Molmil](/molmil-images/mine/2nqh) | |
2QZ0
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![BU of 2qz0 by Molmil](/molmil-images/mine/2qz0) | Mature Q183E variant of Green Fluorescent Protein Chromophore | 分子名称: | Green fluorescent protein, MAGNESIUM ION | 著者 | Wood, T.I, Barondeau, D.P, Hitomi, C, Tainer, J.A, Getzoff, E.D. | 登録日 | 2007-08-15 | 公開日 | 2009-04-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Kinetically Isolated Reaction Intermediates Provide Structural Characterization of the GFP Fluorophore Biosynthesis Pathway To be Published
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1DF1
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![BU of 1df1 by Molmil](/molmil-images/mine/1df1) | MURINE INOSOXY DIMER WITH ISOTHIOUREA BOUND IN THE ACTIVE SITE | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, ETHYLISOTHIOUREA, NITRIC OXIDE SYNTHASE, ... | 著者 | Crane, B.R, Rosenfeld, R.J, Arvai, A.S, Ghosh, D.K, Ghosh, S, Tainer, J.A, Stuehr, D.J, Getzoff, E.D. | 登録日 | 1999-11-16 | 公開日 | 1999-12-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization. EMBO J., 18, 1999
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1DKT
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![BU of 1dkt by Molmil](/molmil-images/mine/1dkt) | CKSHS1: HUMAN CYCLIN DEPENDENT KINASE SUBUNIT, TYPE 1 COMPLEX WITH METAVANADATE | 分子名称: | CYCLIN DEPENDENT KINASE SUBUNIT, TYPE 1, META VANADATE | 著者 | Bourne, Y, Arvai, A.S, Tainer, J.A. | 登録日 | 1995-11-22 | 公開日 | 1996-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of the human cell cycle protein CksHs1: single domain fold with similarity to kinase N-lobe domain. J.Mol.Biol., 249, 1995
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1DKS
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![BU of 1dks by Molmil](/molmil-images/mine/1dks) | CKSHS1: HUMAN CYCLIN DEPENDENT KINASE SUBUNIT, TYPE 1 IN COMPLEX WITH PHOSPHATE | 分子名称: | CYCLIN DEPENDENT KINASE SUBUNIT, TYPE 1, PHOSPHATE ION | 著者 | Bourne, Y, Arvai, A.S, Tainer, J.A. | 登録日 | 1995-11-22 | 公開日 | 1996-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of the human cell cycle protein CksHs1: single domain fold with similarity to kinase N-lobe domain. J.Mol.Biol., 249, 1995
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1EM1
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![BU of 1em1 by Molmil](/molmil-images/mine/1em1) | X-RAY CRYSTAL STRUCTURE FOR HUMAN MANGANESE SUPEROXIDE DISMUTASE, Q143A | 分子名称: | MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE, SULFATE ION | 著者 | Leveque, V, Stroupe, M.E, Lepock, J.R, Cabelli, D.E, Tainer, J.A, Nick, H.S, Silverman, D.N. | 登録日 | 2000-03-14 | 公開日 | 2000-03-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Multiple replacements of glutamine 143 in human manganese superoxide dismutase: effects on structure, stability, and catalysis. Biochemistry, 39, 2000
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1EMJ
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![BU of 1emj by Molmil](/molmil-images/mine/1emj) | URACIL-DNA GLYCOSYLASE BOUND TO DNA CONTAINING A 4'-THIO-2'DEOXYURIDINE ANALOG PRODUCT | 分子名称: | DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*(ASU)P*AP*TP*CP*TP*T)-3'), URACIL, ... | 著者 | Parikh, S.S, Walcher, G, Jones, G.D, Slupphaug, G, Krokan, H.E, Blackburn, G.M, Tainer, J.A. | 登録日 | 2000-03-16 | 公開日 | 2000-05-16 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects. Proc.Natl.Acad.Sci.USA, 97, 2000
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4B22
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![BU of 4b22 by Molmil](/molmil-images/mine/4b22) | Unprecedented sculpting of DNA at abasic sites by DNA glycosylase homolog Mag2 | 分子名称: | 5'-D(*CP*GP*AP*TP*GP*GP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP*(3DR)P*CP*AP*TP*CP*GP)-3', MAG2, ... | 著者 | Dalhus, B, Nilsen, L, Korvald, H, Huffman, J, Forstrom, R.J, McMurray, C.T, Alseth, I, Tainer, J.A, Bjoras, M. | 登録日 | 2012-07-12 | 公開日 | 2013-01-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2. Structure, 21, 2013
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4B21
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![BU of 4b21 by Molmil](/molmil-images/mine/4b21) | Unprecedented sculpting of DNA at abasic sites by DNA glycosylase homolog Mag2 | 分子名称: | 5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP)-3', 5'-D(*GP*CP*TP*AP*CP*3DRP*GP*AP*TP*CP*GP)-3', PHOSPHATE ION, ... | 著者 | Dalhus, B, Nilsen, L, Korvald, H, Huffman, J, Forstrom, R.J, McMurray, C.T, Alseth, I, Tainer, J.A, Bjoras, M. | 登録日 | 2012-07-12 | 公開日 | 2013-01-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Sculpting of DNA at Abasic Sites by DNA Glycosylase Homolog Mag2. Structure, 21, 2013
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4EEU
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![BU of 4eeu by Molmil](/molmil-images/mine/4eeu) | Crystal structure of phiLOV2.1 | 分子名称: | FLAVIN MONONUCLEOTIDE, Phototropin-2 | 著者 | Hitomi, K, Christie, J.M, Arvai, A.S, Hartfield, K.A, Pratt, A.J, Tainer, J.A, Getzoff, E.D. | 登録日 | 2012-03-28 | 公開日 | 2012-05-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.4068 Å) | 主引用文献 | Structural Tuning of the Fluorescent Protein iLOV for Improved Photostability. J.Biol.Chem., 287, 2012
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4ENJ
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![BU of 4enj by Molmil](/molmil-images/mine/4enj) | |