4TPP
 
 | | 2-(3-alkoxy-1-azetidinyl) quinolines as novel PDE10A inhibitors | | 分子名称: | 1-[4-(3-{[1-(quinolin-2-yl)azetidin-3-yl]oxy}quinoxalin-2-yl)piperidin-1-yl]ethanone, GLYCEROL, SULFATE ION, ... | | 著者 | Chmait, S. | | 登録日 | 2014-06-09 | | 公開日 | 2014-12-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Synthesis and preliminary biological evaluation of potent and selective 2-(3-alkoxy-1-azetidinyl) quinolines as novel PDE10A inhibitors with improved solubility.
Bioorg.Med.Chem., 22, 2014
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4TPM
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7S2S
 | | nanobody bound to Interleukin-2Rbeta | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IL2Rb-binding nanobody, Interleukin-2 receptor subunit beta, ... | | 著者 | Glassman, C.R, Jude, K.M, Yen, M, Garcia, K.C. | | 登録日 | 2021-09-03 | | 公開日 | 2022-03-30 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Facile discovery of surrogate cytokine agonists.
Cell, 185, 2022
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7S2R
 | | nanobody bound to IL-2Rg | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ... | | 著者 | Glassman, C.R, Jude, K.M, Yen, M, Garcia, K.C. | | 登録日 | 2021-09-03 | | 公開日 | 2022-03-30 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Facile discovery of surrogate cytokine agonists.
Cell, 185, 2022
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7SBX
 | | Structure of OC43 spike in complex with polyclonal Fab6 (Donor 1051) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... | | 著者 | Bangaru, S, Antanasijevic, A, Ward, A. | | 登録日 | 2021-09-26 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
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2GER
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7SBY
 | | Structure of OC43 spike in complex with polyclonal Fab7 (Donor 269) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... | | 著者 | Bangaru, S, Antanasijevic, A, Ward, A. | | 登録日 | 2021-09-26 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
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7SB3
 | | Structure of OC43 spike in complex with polyclonal Fab1 (Donor 269) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... | | 著者 | Ward, A, Bangaru, S, Antanasijevic, A. | | 登録日 | 2021-09-23 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
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7SB4
 | | Structure of OC43 spike in complex with polyclonal Fab2 (Donor 1412) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... | | 著者 | Bangaru, S, Antanasijevic, A, Ward, A. | | 登録日 | 2021-09-23 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
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7SB5
 | | Structure of OC43 spike in complex with polyclonal Fab3 (Donor 1412) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... | | 著者 | Bangaru, S, Antanasijevic, A, Ward, A. | | 登録日 | 2021-09-23 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
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7SBV
 | | Structure of OC43 spike in complex with polyclonal Fab4 (Donor 269) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... | | 著者 | Bangaru, S, Antanasijevic, A, Ward, A. | | 登録日 | 2021-09-26 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
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7SBW
 | | Structure of OC43 spike in complex with polyclonal Fab5 (Donor 1051) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... | | 著者 | Bangaru, S, Antanasijevic, A, Ward, A. | | 登録日 | 2021-09-26 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural mapping of antibody landscapes to human betacoronavirus spike proteins.
Sci Adv, 8, 2022
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5YHQ
 | | Cryo-EM Structure of CVA6 VLP | | 分子名称: | Capsid protein VP1, Capsid protein VP3, capsid protein VP0 | | 著者 | Chen, J, Zhang, C, Huang, Z, Cong, Y. | | 登録日 | 2017-09-29 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A 3.0-Angstrom Resolution Cryo-Electron Microscopy Structure and Antigenic Sites of Coxsackievirus A6-Like Particles.
J. Virol., 92, 2018
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4PAR
 | | The 5-Hydroxymethylcytosine-Specific Restriction Enzyme AbaSI in a Complex with Product-like DNA | | 分子名称: | 1,2-ETHANEDIOL, DNA 14-MER, DNA 18-MER, ... | | 著者 | Horton, J.R, Cheng, X. | | 登録日 | 2014-04-09 | | 公開日 | 2014-06-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structure of 5-hydroxymethylcytosine-specific restriction enzyme, AbaSI, in complex with DNA.
Nucleic Acids Res., 42, 2014
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5ZKM
 | | Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA TCTTCC | | 分子名称: | DNA (5'-D(P*TP*CP*TP*TP*CP*C)-3'), SP_0782 | | 著者 | Lu, G, Li, S, Zhu, J, Yang, Y, Gong, P. | | 登録日 | 2018-03-24 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural insight into the length-dependent binding of ssDNA by SP_0782 from Streptococcus pneumoniae, reveals a divergence in the DNA-binding interface of PC4-like proteins.
Nucleic Acids Res., 48, 2020
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6IF4
 | | Crystal structure of Tbtudor | | 分子名称: | Histone acetyltransferase | | 著者 | Gao, J, Ye, K, Diwu, Y, Liao, S, Tu, X. | | 登録日 | 2018-09-18 | | 公開日 | 2019-09-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.934 Å) | | 主引用文献 | Crystal structure of TbEsa1 presumed Tudor domain from Trypanosoma brucei.
J.Struct.Biol., 209, 2020
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1O3R
 | | PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES | | 分子名称: | 5'-D(*AP*AP*AP*AP*AP*TP*GP*CP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*GP*CP*AP*TP*TP*TP*TP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... | | 著者 | Chen, S, Vojtechovsky, J, Parkinson, G.N, Ebright, R.H, Berman, H.M. | | 登録日 | 2003-03-18 | | 公開日 | 2003-04-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex: DNA Binding Specificity Based on Energetics of DNA Kinking
J.Mol.Biol., 314, 2001
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1O3Q
 | | PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES | | 分子名称: | 5'-D(*AP*AP*AP*AP*AP*TP*GP*TP*GP*AP*T)-3', 5'-D(*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*TP*TP*TP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... | | 著者 | Chen, S, Vojtechovsky, J, Parkinson, G.N, Ebright, R.H, Berman, H.M. | | 登録日 | 2003-03-18 | | 公開日 | 2003-04-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex: DNA Binding Specificity Based on Energetics of DNA Kinking
J.Mol.Biol., 314, 2001
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1O3T
 | | PROTEIN-DNA RECOGNITION AND DNA DEFORMATION REVEALED IN CRYSTAL STRUCTURES OF CAP-DNA COMPLEXES | | 分子名称: | 5'-D(*CP*TP*AP*GP*AP*TP*CP*GP*CP*AP*TP*TP*TP*TP*TP*CP*G)-3', 5'-D(*GP*CP*GP*AP*AP*AP*AP*AP*TP*GP*CP*GP*AP*T)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... | | 著者 | Chen, S, Vojtechovsky, J, Parkinson, G.N, Ebright, R.H, Berman, H.M. | | 登録日 | 2003-03-18 | | 公開日 | 2003-04-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Indirect Readout of DNA Sequence at the Primary-kink Site in the CAP-DNA Complex:
DNA Binding Specificity Based on Energetics of DNA Kinking
J.Mol.Biol., 314, 2001
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3PL5
 | | Fatty acid binding protein | | 分子名称: | PALMITIC ACID, Putative uncharacterized protein | | 著者 | Lu, Y.Z. | | 登録日 | 2010-11-13 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Lipid binding protein
To be Published
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8X2J
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2GR9
 | | Crystal structure of P5CR complexed with NADH | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLUTAMIC ACID, Pyrroline-5-carboxylate reductase 1 | | 著者 | Meng, Z, Lou, Z, Liu, Z, Rao, Z. | | 登録日 | 2006-04-23 | | 公開日 | 2006-10-03 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structure of human pyrroline-5-carboxylate reductase
J.Mol.Biol., 359, 2006
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8WQW
 | | Cryo-EM structure of bsAb3 Fab-Gn-Gc complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein C, Glycoprotein N, ... | | 著者 | Wu, Y, Sun, J.Q. | | 登録日 | 2023-10-12 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8WSP
 | | Crystal structure of SFTSV Gn and antibody SF5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab5-H, Ab5-L, ... | | 著者 | Chang, Z, Gao, F, Wu, Y. | | 登録日 | 2023-10-17 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model.
Proc.Natl.Acad.Sci.USA, 121, 2024
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8WSN
 | | Crystal structure of SFTSV Gn and antibody SF1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab1-H, ... | | 著者 | Chang, Z, Gao, F, Wu, Y. | | 登録日 | 2023-10-17 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Bispecific antibodies targeting two glycoproteins on SFTSV exhibit synergistic neutralization and protection in a mouse model.
Proc.Natl.Acad.Sci.USA, 121, 2024
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