1IC4
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![BU of 1ic4 by Molmil](/molmil-images/mine/1ic4) | CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A)-HEN LYSOZYME COMPLEX | 分子名称: | IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C | 著者 | Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I. | 登録日 | 2001-03-30 | 公開日 | 2001-07-18 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex. J.Biol.Chem., 276, 2001
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6AJX
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![BU of 6ajx by Molmil](/molmil-images/mine/6ajx) | Crystal structure of BRD4 in complex with isoliquiritigenin in the absence of DMSO | 分子名称: | 2',4,4'-TRIHYDROXYCHALCONE, Bromodomain-containing protein 4, SODIUM ION | 著者 | Yokoyama, T, Matsumoto, K, Nabeshima, Y, Mizuguchi, M. | 登録日 | 2018-08-28 | 公開日 | 2019-06-12 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.887 Å) | 主引用文献 | Structural and thermodynamic characterization of the binding of isoliquiritigenin to the first bromodomain of BRD4. Febs J., 286, 2019
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6AJY
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![BU of 6ajy by Molmil](/molmil-images/mine/6ajy) | Crystal structure of BRD4 in complex with 2',4'-dihydroxy-2-methoxychalcone | 分子名称: | 2',4'-dihydroxy-2-methoxychalcone, Bromodomain-containing protein 4, SODIUM ION | 著者 | Yokoyama, T, Matsumoto, K, Nabeshima, Y, Mizuguchi, M. | 登録日 | 2018-08-28 | 公開日 | 2019-06-12 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural and thermodynamic characterization of the binding of isoliquiritigenin to the first bromodomain of BRD4. Febs J., 286, 2019
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6AJZ
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![BU of 6ajz by Molmil](/molmil-images/mine/6ajz) | Joint nentron and X-ray structure of BRD4 in complex with colchicin | 分子名称: | Bromodomain-containing protein 4, N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]ethanamide, SODIUM ION | 著者 | Yokoyama, T, Ostermann, A, Schrader, T.E, Nabeshima, Y, Mizuguchi, M. | 登録日 | 2018-08-28 | 公開日 | 2019-06-12 | 最終更新日 | 2024-03-27 | 実験手法 | NEUTRON DIFFRACTION (1.301 Å), X-RAY DIFFRACTION | 主引用文献 | Structural and thermodynamic characterization of the binding of isoliquiritigenin to the first bromodomain of BRD4. Febs J., 286, 2019
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6AJW
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![BU of 6ajw by Molmil](/molmil-images/mine/6ajw) | Crystal structure of BRD4 in complex with DMSO (Cocktail No. 4) | 分子名称: | Bromodomain-containing protein 4, DIMETHYL SULFOXIDE, SODIUM ION | 著者 | Yokoyama, T, Matsumoto, K, Nabeshima, Y, Mizuguchi, M. | 登録日 | 2018-08-28 | 公開日 | 2019-06-12 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | 主引用文献 | Structural and thermodynamic characterization of the binding of isoliquiritigenin to the first bromodomain of BRD4. Febs J., 286, 2019
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1WZK
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![BU of 1wzk by Molmil](/molmil-images/mine/1wzk) | Thermoactinomyces vulgaris R-47 alpha-amylase II (TVA II) mutatnt D465N | 分子名称: | Alpha-amylase II, CALCIUM ION | 著者 | Mizuno, M, Ichikawa, K, Tonozuka, T, Ohtaki, A, Shimura, Y, Kamitori, S, Nishikawa, A, Sakano, Y. | 登録日 | 2005-03-06 | 公開日 | 2005-03-22 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mutagenesis and Structural Analysis of Thermoactinomyces vulgaris R-47 alpha-Amylase II (TVA II) To be Published
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1WZL
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![BU of 1wzl by Molmil](/molmil-images/mine/1wzl) | Thermoactinomyces vulgaris R-47 alpha-amylase II (TVA II) mutatnt R469L | 分子名称: | Alpha-amylase II, CALCIUM ION | 著者 | Mizuno, M, Ichikawa, K, Tonozuka, T, Ohtaki, A, Shimura, Y, Kamitori, S, Nishikawa, A, Sakano, Y. | 登録日 | 2005-03-06 | 公開日 | 2005-03-22 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mutagenesis and Structural Analysis of Thermoactinomyces vulgaris R-47 alpha-Amylase II (TVA II) To be Published
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1WZM
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![BU of 1wzm by Molmil](/molmil-images/mine/1wzm) | Thermoactinomyces vulgaris R-47 alpha-amylase II (TVA II) mutatnt R469K | 分子名称: | Alpha-amylase II, CALCIUM ION | 著者 | Mizuno, M, Ichikawa, K, Tonozuka, T, Ohtaki, A, Shimura, Y, Kamitori, S, Nishikawa, A, Sakano, Y. | 登録日 | 2005-03-06 | 公開日 | 2005-03-22 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Mutagenesis and Structural Analysis of Thermoactinomyces vulgaris R-47 alpha-Amylase II (TVA II) To be Published
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1IC7
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![BU of 1ic7 by Molmil](/molmil-images/mine/1ic7) | CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD32A99A)-HEN LYSOZYME COMPLEX | 分子名称: | IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C | 著者 | Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I. | 登録日 | 2001-03-30 | 公開日 | 2001-07-18 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex. J.Biol.Chem., 276, 2001
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1IC5
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![BU of 1ic5 by Molmil](/molmil-images/mine/1ic5) | CRYSTAL STRUCTURE OF HYHEL-10 FV MUTANT(HD99A)-HEN LYSOZYME COMPLEX | 分子名称: | IGG1 FAB CHAIN H, LYSOZYME BINDING IG KAPPA CHAIN, LYSOZYME C | 著者 | Shiroishi, M, Yokota, A, Tsumoto, K, Kondo, H, Nishimiya, Y, Horii, K, Matsushima, M, Ogasahara, K, Yutani, K, Kumagai, I. | 登録日 | 2001-03-30 | 公開日 | 2001-07-18 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction: the case of hen lysozyme-HyHEL-10 Fv complex. J.Biol.Chem., 276, 2001
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1KWH
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![BU of 1kwh by Molmil](/molmil-images/mine/1kwh) | Structure Analysis AlgQ2, a Macromolecule(alginate)-Binding Periplasmic Protein of Sphingomonas sp. A1. | 分子名称: | CALCIUM ION, Macromolecule-Binding Periplasmic Protein | 著者 | Momma, K, Mikami, B, Mishima, Y, Hashimoto, W, Murata, K. | 登録日 | 2002-01-29 | 公開日 | 2002-02-13 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of AlgQ2, a macromolecule (alginate)-binding protein of Sphingomonas sp. A1 at 2.0A resolution. J.Mol.Biol., 316, 2002
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1Y3Q
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![BU of 1y3q by Molmil](/molmil-images/mine/1y3q) | Structure of AlgQ1, alginate-binding protein | 分子名称: | AlgQ1, CALCIUM ION | 著者 | Momma, K, Mishima, Y, Hashimoto, W, Mikami, B, Murata, K. | 登録日 | 2004-11-26 | 公開日 | 2005-04-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Direct Evidence for Sphingomonas sp. A1 Periplasmic Proteins as Macromolecule-Binding Proteins Associated with the ABC Transporter: Molecular Insights into Alginate Transport in the Periplasm(,) Biochemistry, 44, 2005
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1Y3P
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![BU of 1y3p by Molmil](/molmil-images/mine/1y3p) | Structure of AlgQ1, alginate-binding protein, complexed with an alginate tetrasaccharide | 分子名称: | AlgQ1, CALCIUM ION, beta-D-mannopyranuronic acid-(1-4)-alpha-D-mannopyranuronic acid-(1-4)-alpha-L-gulopyranuronic acid-(1-4)-alpha-D-mannopyranuronic acid | 著者 | Momma, K, Mishima, Y, Hashimoto, W, Mikami, B, Murata, K. | 登録日 | 2004-11-26 | 公開日 | 2005-04-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Direct Evidence for Sphingomonas sp. A1 Periplasmic Proteins as Macromolecule-Binding Proteins Associated with the ABC Transporter: Molecular Insights into Alginate Transport in the Periplasm(,) Biochemistry, 44, 2005
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1Y3N
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![BU of 1y3n by Molmil](/molmil-images/mine/1y3n) | Structure of AlgQ1, alginate-binding protein, complexed with an alginate disaccharide | 分子名称: | AlgQ1, CALCIUM ION, beta-D-mannopyranuronic acid-(1-4)-alpha-D-mannopyranuronic acid | 著者 | Momma, K, Mishima, Y, Hashimoto, W, Mikami, B, Murata, K. | 登録日 | 2004-11-26 | 公開日 | 2005-04-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Direct Evidence for Sphingomonas sp. A1 Periplasmic Proteins as Macromolecule-Binding Proteins Associated with the ABC Transporter: Molecular Insights into Alginate Transport in the Periplasm(,) Biochemistry, 44, 2005
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3U2J
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![BU of 3u2j by Molmil](/molmil-images/mine/3u2j) | Neutron crystal structure of human Transthyretin | 分子名称: | Transthyretin | 著者 | Yokoyama, T, Mizuguchi, M, Nabeshima, Y, Kusaka, K, Yamada, T, Hosoya, T, Ohhara, T, Kurihara, K, Tomoyori, K, Tanaka, I, Niimura, N. | 登録日 | 2011-10-03 | 公開日 | 2012-02-22 | 最終更新日 | 2023-11-01 | 実験手法 | NEUTRON DIFFRACTION (2 Å) | 主引用文献 | Hydrogen-bond network and pH sensitivity in transthyretin: Neutron crystal structure of human transthyretin J.Struct.Biol., 177, 2012
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3U2I
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![BU of 3u2i by Molmil](/molmil-images/mine/3u2i) | X-ray crystal structure of human Transthyretin at room temperature | 分子名称: | Transthyretin | 著者 | Yokoyama, T, Mizuguchi, M, Nabeshima, Y, Kusaka, K, Yamada, T, Hosoya, T, Ohhara, T, Kurihara, K, Tomoyori, K, Tanaka, I, Niimura, N. | 登録日 | 2011-10-03 | 公開日 | 2012-02-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Hydrogen-bond network and pH sensitivity in transthyretin: Neutron crystal structure of human transthyretin J.Struct.Biol., 177, 2012
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2LX3
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![BU of 2lx3 by Molmil](/molmil-images/mine/2lx3) | 1H,13C,15N assignments for an isoform of the type III antifreeze protein from notched-fin eelpout | 分子名称: | Type III antifreeze protein nfeAFP11 | 著者 | Kumeta, H, Ogura, K, Nishimiya, Y, Miura, A, Inagaki, F, Tsuda, S. | 登録日 | 2012-08-12 | 公開日 | 2013-07-24 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure note: a defective isoform and its activity-improved variant of a type III antifreeze protein from Zoarces elongates Kner J.Biomol.Nmr, 55, 2013
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2LX2
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![BU of 2lx2 by Molmil](/molmil-images/mine/2lx2) | 1H,13C,15N assignments for an isoform of the type III antifreeze protein from notched-fin eelpout | 分子名称: | Type III antifreeze protein nfeAFP11 | 著者 | Kumeta, H, Ogura, K, Nishimiya, Y, Miura, A, Inagaki, F, Tsuda, S. | 登録日 | 2012-08-12 | 公開日 | 2013-07-24 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure note: a defective isoform and its activity-improved variant of a type III antifreeze protein from Zoarces elongates Kner J.Biomol.Nmr, 55, 2013
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7W9Q
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![BU of 7w9q by Molmil](/molmil-images/mine/7w9q) | Crystal structure of V30M-TTR in complex with naringenin derivative-14 | 分子名称: | (2~{R})-2-(3-chloranyl-4-oxidanyl-phenyl)-5,7-bis(oxidanyl)-2,3-dihydrochromen-4-one, CALCIUM ION, Transthyretin | 著者 | Katayama, W, Shimane, A, Nabeshima, Y, Yokoyama, T, Mizuguchi, M. | 登録日 | 2021-12-10 | 公開日 | 2022-12-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | 主引用文献 | Chlorinated Naringenin Analogues as Potential Inhibitors of Transthyretin Amyloidogenesis. J.Med.Chem., 65, 2022
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7W9R
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![BU of 7w9r by Molmil](/molmil-images/mine/7w9r) | Crystal structure of V30M-TTR in complex with naringenin derivative-18 | 分子名称: | (2~{R})-2-[3,5-bis(chloranyl)-4-oxidanyl-phenyl]-5,7-bis(oxidanyl)-2,3-dihydrochromen-4-one, Transthyretin | 著者 | Katayama, W, Shimane, A, Nabeshima, Y, Yokoyama, T, Mizuguchi, M. | 登録日 | 2021-12-10 | 公開日 | 2022-12-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Chlorinated Naringenin Analogues as Potential Inhibitors of Transthyretin Amyloidogenesis. J.Med.Chem., 65, 2022
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5GOW
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![BU of 5gow by Molmil](/molmil-images/mine/5gow) | |
8YFY
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![BU of 8yfy by Molmil](/molmil-images/mine/8yfy) | CRYSTAL STRUCTURE OF THE EST1 H274D MUTANT AT PH 4.2 | 分子名称: | Carboxylesterase, octyl beta-D-glucopyranoside | 著者 | Unno, H, Oshima, Y, Nishino, T, Nakayama, T, Kusunoki, M. | 登録日 | 2024-02-26 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Lowering pH optimum of activity of SshEstI, a slightly alkaliphilic archaeal esterase of the hormone-sensitive lipase family. J.Biosci.Bioeng., 2024
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8YFZ
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![BU of 8yfz by Molmil](/molmil-images/mine/8yfz) | CRYSTAL STRUCTURE OF THE EST1 H274E MUTANT AT PH 4.2 | 分子名称: | Carboxylesterase, octyl beta-D-glucopyranoside | 著者 | Unno, H, Oshima, Y, Nishino, T, Nakayama, T, Kusunoki, M. | 登録日 | 2024-02-26 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Lowering pH optimum of activity of SshEstI, a slightly alkaliphilic archaeal esterase of the hormone-sensitive lipase family. J.Biosci.Bioeng., 2024
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1IR8
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![BU of 1ir8 by Molmil](/molmil-images/mine/1ir8) | |
7DTI
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![BU of 7dti by Molmil](/molmil-images/mine/7dti) | |