3WTS
 
 | | Crystal structure of the complex comprised of ETS1, RUNX1, CBFBETA, and the tcralpha gene enhancer DNA | | 分子名称: | 5'-D(*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3', 5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3', Core-binding factor subunit beta, ... | | 著者 | Shiina, M, Hamada, K, Ogata, K. | | 登録日 | 2014-04-21 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
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3WU1
 | | Crystal structure of the ETS1-RUNX1-DNA ternary complex | | 分子名称: | DNA (5'-D(*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), Protein C-ets-1, ... | | 著者 | Tahirov, T.H, Ogata, K. | | 登録日 | 2014-04-21 | | 公開日 | 2014-08-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions.
J.Mol.Biol., 427, 2015
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3UP6
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2ZK9
 | | Crystal Structure of Protein-glutaminase | | 分子名称: | GLYCEROL, Protein-glutaminase, SODIUM ION | | 著者 | Hashizume, R. | | 登録日 | 2008-03-13 | | 公開日 | 2009-03-17 | | 最終更新日 | 2012-08-29 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Crystal structures of protein glutaminase and its pro forms converted into enzyme-substrate complex
J.Biol.Chem., 286, 2011
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3A56
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3A55
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3A54
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3WV3
 | | Crystal structure of the catalytic domain of MMP-13 complexed with N-(3-methoxybenzyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-2-carboxamide | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Collagenase 3, ... | | 著者 | Oki, H, Tanaka, Y. | | 登録日 | 2014-05-12 | | 公開日 | 2014-09-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1′′ binding site.
Bioorg.Med.Chem., 22, 2014
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3WV1
 | | Crystal structure of the catalytic domain of MMP-13 complexed with 4-(2-((6-fluoro-2-((3-methoxybenzyl)carbamoyl)-4-oxo-3,4-dihydroquinazolin-5-yl)oxy)ethyl)benzoic acid | | 分子名称: | 4-[2-({6-fluoro-2-[(3-methoxybenzyl)carbamoyl]-4-oxo-3,4-dihydroquinazolin-5-yl}oxy)ethyl]benzoic acid, CALCIUM ION, Collagenase 3, ... | | 著者 | Oki, H, Tanaka, Y. | | 登録日 | 2014-05-12 | | 公開日 | 2015-05-20 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Discovery of novel, highly potent, and selective quinazoline-2-carboxamide-based matrix metalloproteinase (MMP)-13 inhibitors without a zinc binding group using a structure-based design approach
J.Med.Chem., 57, 2014
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3WV2
 | | Crystal structure of the catalytic domain of MMP-13 complexed with N-(3-methoxybenzyl)-4-oxo-3,4-dihydroquinazoline-2-carboxamide | | 分子名称: | CALCIUM ION, Collagenase 3, N-(3-methoxybenzyl)-4-oxo-3,4-dihydroquinazoline-2-carboxamide, ... | | 著者 | Oki, H, Tanaka, Y. | | 登録日 | 2014-05-12 | | 公開日 | 2014-09-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1′′ binding site.
Bioorg.Med.Chem., 22, 2014
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2EC7
 | | Solution Structure of Human Immunodificiency Virus Type-2 Nucleocapsid Protein | | 分子名称: | Gag polyprotein (Pr55Gag), ZINC ION | | 著者 | Matsui, T, Kodera, Y, Tanaka, T, Endoh, H, Tanaka, H, Miyauchi, E, Komatsu, H, Kohno, T, Maeda, T. | | 登録日 | 2007-02-10 | | 公開日 | 2008-02-19 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The RNA recognition mechanism of human immunodeficiency virus (HIV) type 2 NCp8 is different from that of HIV-1 NCp7
Biochemistry, 48, 2009
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3VW3
 | | Antibody 64M-5 Fab in complex with a double-stranded DNA (6-4) photoproduct | | 分子名称: | Anti-(6-4) photoproduct antibody 64M-5 Fab (heavy chain), Anti-(6-4) photoproduct antibody 64M-5 Fab (light chain), COBALT HEXAMMINE(III), ... | | 著者 | Yokoyama, H, Mizutani, R, Satow, Y. | | 登録日 | 2012-07-30 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of a double-stranded DNA (6-4) photoproduct in complex with the 64M-5 antibody Fab
Acta Crystallogr.,Sect.D, 69, 2013
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