3A4X
 
 | | Crystal structures of catalytic site mutants of active domain 2 of thermostable chitinase from Pyrococcus furiosus complexed with chito-oligosaccharides | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Chitinase, GLYCEROL, ... | | 著者 | Tsuji, H, Nishimura, S, Inui, T, Ishikawa, K, Nakamura, T, Uegaki, K. | | 登録日 | 2009-07-22 | | 公開日 | 2010-06-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus- the role of conserved residues in the active site
Febs J., 277, 2010
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3A4W
 | | Crystal structures of catalytic site mutants of active domain 2 of thermostable chitinase from Pyrococcus furiosus complexed with chito-oligosaccharides | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase, MAGNESIUM ION, ... | | 著者 | Tsuji, H, Nishimura, S, Inui, T, Ishikawa, K, Nakamura, T, Uegaki, K. | | 登録日 | 2009-07-22 | | 公開日 | 2010-06-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Kinetic and crystallographic analyses of the catalytic domain of chitinase from Pyrococcus furiosus- the role of conserved residues in the active site
Febs J., 277, 2010
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3ALQ
 | | Crystal structure of TNF-TNFR2 complex | | 分子名称: | COBALT (II) ION, Tumor necrosis factor, Tumor necrosis factor receptor superfamily member 1B | | 著者 | Mukai, Y, Nakamura, T, Yamagata, Y, Tsutsumi, Y. | | 登録日 | 2010-08-06 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Solution of the Structure of the TNF-TNFR2 Complex
Sci.Signal., 3, 2010
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5ZSS
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8H3M
 | | Conformation 1 of SARS-CoV-2 Omicron BA.1 Variant Spike protein complexed with MO1 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MO1 heavy chain, Spike glycoprotein | | 著者 | Ishimaru, H, Nishimura, M, Sutandhio, S, Shigematsu, H, Kato, K, Hasegawa, N, Mori, Y. | | 登録日 | 2022-10-09 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (2.48 Å) | | 主引用文献 | Identification and Analysis of Monoclonal Antibodies with Neutralizing Activity against Diverse SARS-CoV-2 Variants.
J.Virol., 97, 2023
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8H3N
 | | Conformation 2 of SARS-CoV-2 Omicron BA.1 Variant Spike protein complexed with MO1 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MO1 heavy-chain, MO1 light chain, ... | | 著者 | Ishimaru, H, Nishimura, M, Sutandhio, S, Shigematsu, H, Kato, K, Hasegawa, N, Mori, Y. | | 登録日 | 2022-10-09 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | | 主引用文献 | Identification and Analysis of Monoclonal Antibodies with Neutralizing Activity against Diverse SARS-CoV-2 Variants.
J.Virol., 97, 2023
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2RTS
 | | Chitin binding domain1 | | 分子名称: | chitinase | | 著者 | Uegaki, K. | | 登録日 | 2013-08-19 | | 公開日 | 2014-04-23 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the chitin-binding domain 1 (ChBD1) of a hyperthermophilic chitinase from Pyrococcus furiosus.
J.Biochem., 155, 2014
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8Q8J
 | | Crystal structure of human GPX4-R152H | | 分子名称: | Glutathione peroxidase | | 著者 | Napolitano, V, Mourao, A, Kolonko, M, Bostock, M.J, Sattler, M, Conrad, M, Popowicz, G. | | 登録日 | 2023-08-18 | | 公開日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of human GPX4-R152H
To Be Published
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8Q8N
 | | Crystal structure of human GPX4-U46C-I129S-L130S | | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase | | 著者 | Bostock, M.J, Mourao, A, Napolitano, V, Sattler, M, Conrad, M, Popowicz, G. | | 登録日 | 2023-08-18 | | 公開日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | An ultra-rare variant of GPX4 reveals the structural basis to avert neurodegeneration
To Be Published
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3L85
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8YEK
 | | Cryo-EM structure of the channelrhodopsin GtCCR2 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GtCCR2, RETINAL | | 著者 | Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. | | 登録日 | 2024-02-22 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | | 主引用文献 | The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4.
Mol.Cell, 84, 2024
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8YEL
 | | Cryo-EM structure of the channelrhodopsin GtCCR4 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cation channel rhodopsin 4, RETINAL | | 著者 | Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. | | 登録日 | 2024-02-22 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4.
Mol.Cell, 84, 2024
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8YEJ
 | | Cryo-EM structure of the channelrhodopsin GtCCR2 focused on the monomer | | 分子名称: | GtCCR2, RETINAL | | 著者 | Tanaka, T, Iida, W, Sano, F.K, Oda, K, Shihoya, W, Nureki, O. | | 登録日 | 2024-02-22 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | | 主引用文献 | The high-light-sensitivity mechanism and optogenetic properties of the bacteriorhodopsin-like channelrhodopsin GtCCR4.
Mol.Cell, 84, 2024
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2EAL
 | | Crystal structure of human galectin-9 N-terminal CRD in complex with Forssman pentasaccharide | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)-beta-D-galactopyranose, Galectin-9 | | 著者 | Nagae, M, Nakamura-Tsuruta, S, Nishi, N, Nakamura, T, Hirabayashi, J, Wakatsuki, S, Kato, R. | | 登録日 | 2007-01-31 | | 公開日 | 2007-09-25 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue.
J.Mol.Biol., 375, 2008
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2EAK
 | | Crystal structure of human galectin-9 N-terminal CRD in complex with lactose | | 分子名称: | (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, GLYCEROL, Galectin-9, ... | | 著者 | Nagae, M, Nakamura-Tsuruta, S, Nishi, N, Nakamura, T, Hirabayashi, J, Wakatsuki, S, Kato, R. | | 登録日 | 2007-01-31 | | 公開日 | 2007-09-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue.
J.Mol.Biol., 375, 2008
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1IRE
 | | Crystal Structure of Co-type nitrile hydratase from Pseudonocardia thermophila | | 分子名称: | COBALT (II) ION, Nitrile Hydratase | | 著者 | Miyanaga, A, Fushinobu, S, Ito, K, Wakagi, T. | | 登録日 | 2001-10-01 | | 公開日 | 2002-10-01 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of cobalt-containing nitrile hydratase.
Biochem.Biophys.Res.Commun., 288, 2001
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6D0D
 | | X-ray crystal structure of wild type HIV-1 protease in complex with GRL-087-13 | | 分子名称: | (3aS,4S,7aR)-hexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-1-(4-fluorophenyl)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}butan-2-yl]carbamate, Protease | | 著者 | Yedidi, R.S, Hayashi, H, Ghosh, A.K, Mitsuya, H. | | 登録日 | 2018-04-10 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Novel Central Nervous System (CNS)-Targeting Protease Inhibitors for Drug-Resistant HIV Infection and HIV-Associated CNS Complications.
Antimicrob.Agents Chemother., 63, 2019
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6D0E
 | | X-ray crystal structure of wild type HIV-1 protease in complex with GRL-084-13 | | 分子名称: | (3aS,4S,7aR)-hexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}butan-2-yl]carbamate, Protease | | 著者 | Yedidi, R.S, Hayashi, H, Ghosh, A.K, Mitsuya, H. | | 登録日 | 2018-04-10 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Novel Central Nervous System (CNS)-Targeting Protease Inhibitors for Drug-Resistant HIV Infection and HIV-Associated CNS Complications.
Antimicrob.Agents Chemother., 63, 2019
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4RKW
 | | Crystal structure of DJ-1 | | 分子名称: | Protein DJ-1 | | 著者 | Liddington, R.C. | | 登録日 | 2014-10-14 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Transnitrosylation from DJ-1 to PTEN attenuates neuronal cell death in parkinson's disease models.
J.Neurosci., 34, 2014
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4RKY
 | | Crystal structure of DJ-1 isoform X1 | | 分子名称: | Protein DJ-1 | | 著者 | Liddington, R.C. | | 登録日 | 2014-10-14 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Transnitrosylation from DJ-1 to PTEN attenuates neuronal cell death in parkinson's disease models.
J.Neurosci., 34, 2014
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1K37
 | | NMR Structure of human Epiregulin | | 分子名称: | Epiregulin | | 著者 | Sato, K, Miura, K, Tada, M, Aizawa, T, Miyamoto, K, Kawano, K. | | 登録日 | 2001-10-02 | | 公開日 | 2003-09-30 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of epiregulin and the effect of its C-terminal domain for receptor binding affinity
Febs Lett., 553, 2003
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1K36
 | | NMR Structure of human Epiregulin | | 分子名称: | Epiregulin | | 著者 | Sato, K, Miura, K, Tada, M, Aizawa, T, Miyamoto, K, Kawano, K. | | 登録日 | 2001-10-02 | | 公開日 | 2003-09-30 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of epiregulin and the effect of its C-terminal domain for receptor binding affinity
Febs Lett., 553, 2003
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3NV4
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3NV3
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3NV2
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