6BLQ
 
 | | Crystal Structure of IAg7 in complex with insulin mimotope p8E9E | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wang, Y, Dai, S. | | 登録日 | 2017-11-11 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6BLR
 | |
6BLX
 | | Crystal structure of IAg7 in complex with insulin mimotope p8G9E | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wang, Y, Dai, S. | | 登録日 | 2017-11-11 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.323 Å) | | 主引用文献 | C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
5X6D
 | | Crystal structure of PrfA-DNA binary complex | | 分子名称: | DNA (28-MER), DNA (29-MER), Listeriolysin positive regulatory factor A | | 著者 | Wang, Y, Feng, H, Zhu, Y.L, Gao, P. | | 登録日 | 2017-02-21 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | | 主引用文献 | Structural insights into glutathione-mediated activation of the master regulator PrfA in Listeria monocytogenes
Protein Cell, 8, 2017
|
|
2IMI
 | | Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity | | 分子名称: | Epsilon-class Glutathione S-transferase, GLUTATHIONE | | 著者 | Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L. | | 登録日 | 2006-10-02 | | 公開日 | 2007-10-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
|
|
5X6E
 | | Crystal structure of PrfA-DNA binary complex | | 分子名称: | DNA (28-MER), DNA (29-MER), GLUTATHIONE, ... | | 著者 | Wang, Y, Feng, H, Zhu, Y.L, Gao, P. | | 登録日 | 2017-02-21 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Structural insights into glutathione-mediated activation of the master regulator PrfA in Listeria monocytogenes
Protein Cell, 8, 2017
|
|
2IL3
 | | Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity | | 分子名称: | Epsilon-class Glutathione S-transferase | | 著者 | Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L. | | 登録日 | 2006-10-02 | | 公開日 | 2007-10-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
|
|
2IMK
 | | Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity | | 分子名称: | Epsilon-class Glutathione S-transferase, S-HEXYLGLUTATHIONE | | 著者 | Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L. | | 登録日 | 2006-10-02 | | 公開日 | 2007-10-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
|
|
8XIO
 | | Structure of L797591-SSTR1 G protein complex | | 分子名称: | (2~{S})-~{N}-[(4~{S})-6-azanyl-2,2,4-trimethyl-hexyl]-3-naphthalen-1-yl-2-[[2-phenylethyl(2-pyridin-2-ylethyl)carbamoyl]amino]propanamide, G-alpha-i, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Wang, Y, Xu, Y, Xu, H.E, Zhuang, Y. | | 登録日 | 2023-12-19 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | | 主引用文献 | Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3
To Be Published
|
|
8XIR
 | | Structure of pasireotide-SSTR3 G protein complex | | 分子名称: | G-alpha i, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Wang, Y, Xu, Y, Xu, H.E, Zhuang, Y. | | 登録日 | 2023-12-19 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | | 主引用文献 | Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3
To Be Published
|
|
8XIP
 | | Structure of Pasireotide-SSTR1 G protein complex | | 分子名称: | 004-DTR-LYS-TY5-PHE-A1D5E, G-alpha i, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Wang, Y, Xu, Y, Xu, H.E, Zhuang, Y. | | 登録日 | 2023-12-19 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3
To Be Published
|
|
8IUO
 | | respiratory syncytial virus nucleocapsid-like assembly | | 分子名称: | Nucleoprotein, RNA (35-MER) | | 著者 | Wang, Y, Luo, Y, Ling, X, Luo, B, Jia, G, Dong, H, Su, Z. | | 登録日 | 2023-03-24 | | 公開日 | 2023-09-06 | | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | | 主引用文献 | Cryo-EM structure of the nucleocapsid-like assembly of respiratory syncytial virus.
Signal Transduct Target Ther, 8, 2023
|
|
8XIQ
 | | Structure of L796778-SSTR3 G protein complex | | 分子名称: | G-alpha i, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Wang, Y, Xu, Y, Xu, H.E, Zhuang, Y. | | 登録日 | 2023-12-19 | | 公開日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3
To Be Published
|
|
2K48
 | | NMR Structure of the N-terminal Coiled Coil Domain of the Andes Hantavirus Nucleocapsid Protein | | 分子名称: | Nucleoprotein | | 著者 | Wang, Y, Boudreaux, D.M, Estrada, D.F, Egan, C.W, St Jeor, S.C, De Guzman, R.N. | | 登録日 | 2008-05-30 | | 公開日 | 2008-08-05 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structure of the N-terminal Coiled Coil Domain of the Andes Hantavirus Nucleocapsid Protein.
J.Biol.Chem., 283, 2008
|
|
5ZQ4
 | | PDE-Ubi-ADPr | | 分子名称: | ADENOSINE MONOPHOSPHATE, SidE, ubiquitin | | 著者 | Wang, Y, Gao, A, Gao, P. | | 登録日 | 2018-04-17 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.217 Å) | | 主引用文献 | Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
|
|
5ZQ3
 | | PDE-Ubiquitin | | 分子名称: | SidE, Ubiquitin | | 著者 | Wang, Y, Gao, A, Gao, P. | | 登録日 | 2018-04-17 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.182 Å) | | 主引用文献 | Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
|
|
5ZQ2
 | | SidE apo form | | 分子名称: | SidE | | 著者 | Wang, Y, Gao, A, Gao, P. | | 登録日 | 2018-04-17 | | 公開日 | 2018-05-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.704 Å) | | 主引用文献 | Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE.
Cell, 173, 2018
|
|
8I2B
 | | Human SIRT6 in complex with inhibitor 7702 | | 分子名称: | N1-[[4-(4-aminophenyl)sulfanyl-3-(trifluoromethyl)phenyl]methoxy]benzene-1,4-dicarboxamide, NAD-dependent protein deacylase sirtuin-6, SULFATE ION, ... | | 著者 | Wang, Y. | | 登録日 | 2023-01-14 | | 公開日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The SIRT6 in complex with inhibitor 7702
To Be Published
|
|
7WO2
 | | SARS-CoV-2 3CLPro Peptidomimetic Inhibitor TPM5 | | 分子名称: | 3C-like proteinase, N-[(2S)-3-methyl-1-[[(2S)-4-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanylidene-3-[(3S}-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]furan-2-carboxamide | | 著者 | Wang, Y, Ye, S. | | 登録日 | 2022-01-20 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Discovery of SARS-CoV-2 3CL Pro Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein-Ligand Interactions.
Int J Mol Sci, 23, 2022
|
|
7WOF
 | | SARS-CoV-2 3CLpro | | 分子名称: | (2S,3S)-3-methyl-N-[(2S)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepiperidin-3-yl]propan-2-yl]-2-[[(E)-3-phenylprop-2-enoyl]amino]pentanamide, 3C-like proteinase | | 著者 | Wang, Y, Ye, S. | | 登録日 | 2022-01-21 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Discovery of SARS-CoV-2 3CL Pro Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein-Ligand Interactions.
Int J Mol Sci, 23, 2022
|
|
7WO1
 | |
7WO3
 | | SARS-CoV-2 3CLpro | | 分子名称: | (2S)-2-[[(2S)-2-[[(E)-3-(4-methoxyphenyl)prop-2-enoyl]amino]-3-methyl-butanoyl]amino]-4-methyl-N-[(2S)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepiperidin-3-yl]propan-2-yl]pentanamide, 3C-like proteinase | | 著者 | Wang, Y, Ye, S. | | 登録日 | 2022-01-20 | | 公開日 | 2022-04-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Discovery of SARS-CoV-2 3CL Pro Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein-Ligand Interactions.
Int J Mol Sci, 23, 2022
|
|
7WOH
 | | SARS-CoV-2 3CLpro | | 分子名称: | (2S)-4-methyl-N-[(2S)-1-oxidanylidene-3-[(3S)-2-oxidanylidenepiperidin-3-yl]propan-2-yl]-2-[[(2S)-3-phenyl-2-[[(E)-3-phenylprop-2-enoyl]amino]propanoyl]amino]pentanamide, 3C-like proteinase | | 著者 | Wang, Y, Ye, S. | | 登録日 | 2022-01-21 | | 公開日 | 2022-04-13 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Discovery of SARS-CoV-2 3CL Pro Peptidomimetic Inhibitors through the Catalytic Dyad Histidine-Specific Protein-Ligand Interactions.
Int J Mol Sci, 23, 2022
|
|
7Y3E
 | |
6VI8
 | | Observing a ring-cleaving dioxygenase in action through a crystalline lens - a superoxo bound structure | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-HYDROXYANTHRANILIC ACID, 3-hydroxyanthranilate 3,4-dioxygenase, ... | | 著者 | Wang, Y, Liu, F, Yang, Y, Liu, A. | | 登録日 | 2020-01-12 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
