1YJD
| Crystal structure of human CD28 in complex with the Fab fragment of a mitogenic antibody (5.11A1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab fragment of 5.11A1 antibody heavy chain, Fab fragment of 5.11A1 antibody light chain, ... | 著者 | Evans, E.J, Esnouf, R.M, Manso-Sancho, R, Gilbert, R.J.C, James, J.R, Sorensen, P, Stuart, D.I, Davis, S.J. | 登録日 | 2005-01-14 | 公開日 | 2005-02-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of a soluble CD28-Fab complex Nat.Immunol., 6, 2005
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4QPI
| Crystal structure of hepatitis A virus | 分子名称: | CHLORIDE ION, Capsid protein VP1, Capsid protein VP2, ... | 著者 | Wang, X, Ren, J, Gao, Q, Hu, Z, Sun, Y, Li, X, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | 登録日 | 2014-06-23 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Hepatitis A virus and the origins of picornaviruses. Nature, 517, 2015
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1ZBA
| Foot-and-Mouth Disease virus serotype A1061 complexed with oligosaccharide receptor. | 分子名称: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Coat protein VP1, Coat protein VP2, ... | 著者 | Fry, E.E, Newman, J.W, Curry, S, Najjam, S, Jackson, T, Blakemore, W, Lea, S.M, Miller, L, Burman, A, King, A.M, Stuart, D.I. | 登録日 | 2005-04-08 | 公開日 | 2005-06-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of Foot-and-mouth disease virus serotype A1061 alone and complexed with oligosaccharide receptor: receptor conservation in the face of antigenic variation. J.Gen.Virol., 86, 2005
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1ZBE
| Foot-and Mouth Disease Virus Serotype A1061 | 分子名称: | Coat protein VP1, Coat protein VP2, Coat protein VP3, ... | 著者 | Fry, E.E, Newman, J.W, Curry, S, Najjam, S, Jackson, T, Blakemore, W, Lea, S.M, Miller, L, Burman, A, King, A.M, Stuart, D.I. | 登録日 | 2005-04-08 | 公開日 | 2005-06-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of Foot-and-mouth disease virus serotype A1061 alone and complexed with oligosaccharide receptor: receptor conservation in the face of antigenic variation. J.Gen.Virol., 86, 2005
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295D
| CRYSTAL AND SOLUTION STRUCTURES OF THE OLIGONUCLEOTIDE D(ATGCGCAT)2: A COMBINED X-RAY AND NMR STUDY | 分子名称: | DNA (5'-D(*AP*TP*GP*CP*GP*CP*AP*T)-3') | 著者 | Clark, G.R, Brown, D.G, Sanderson, M.R, Chwalinski, T, Neidle, S, Veal, J.M, Jones, R.L, Wilson, W.D, Zon, G, Garman, E, Stuart, D.I. | 登録日 | 1991-05-28 | 公開日 | 1996-12-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal and solution structures of the oligonucleotide d(ATGCGCAT)2: a combined X-ray and NMR study. Nucleic Acids Res., 18, 1990
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4QPG
| Crystal structure of empty hepatitis A virus | 分子名称: | CHLORIDE ION, Capsid protein VP0, Capsid protein VP1, ... | 著者 | Wang, X, Ren, J, Gao, Q, Hu, Z, Sun, Y, Li, X, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | 登録日 | 2014-06-23 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Hepatitis A virus and the origins of picornaviruses. Nature, 517, 2015
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1MU2
| CRYSTAL STRUCTURE OF HIV-2 REVERSE TRANSCRIPTASE | 分子名称: | GLYCEROL, HIV-2 RT, SULFATE ION | 著者 | Ren, J, Bird, L.E, Chamberlain, P.P, Stewart-Jones, G.B, Stuart, D.I, Stammers, D.K. | 登録日 | 2002-09-23 | 公開日 | 2002-10-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors Proc.Natl.Acad.Sci.USA, 99, 2002
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6F5U
| CRYSTAL STRUCTURE OF EBOLAVIRUS GLYCOPROTEIN IN COMPLEX WITH BEPRIDIL | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bepridil, DIMETHYL SULFOXIDE, ... | 著者 | Ren, J, Zhao, Y, Fry, E.E, Stuart, D.I. | 登録日 | 2017-12-03 | 公開日 | 2018-01-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Target Identification and Mode of Action of Four Chemically Divergent Drugs against Ebolavirus Infection. J. Med. Chem., 61, 2018
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6G9B
| Crystal structure of Ebolavirus glycoprotein in complex with imipramine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, ... | 著者 | Zhao, Y, Ren, J, Fry, E.E, Xiao, J, Townsend, A.R, Stuart, D.I. | 登録日 | 2018-04-10 | 公開日 | 2018-05-23 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs. J. Med. Chem., 61, 2018
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6G95
| Crystal structure of Ebolavirus glycoprotein in complex with thioridazine | 分子名称: | 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Zhao, Y, Ren, J, Fry, E.E, Xiao, J, Townsend, A.R, Stuart, D.I. | 登録日 | 2018-04-10 | 公開日 | 2018-05-23 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs. J. Med. Chem., 61, 2018
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6H3B
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6G9I
| Crystal structure of Ebolavirus glycoprotein in complex with clomipramine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, Envelope glycoprotein,Envelope glycoprotein, ... | 著者 | Zhao, Y, Ren, J, Fry, E.E, Xiao, J, Townsend, A.R, Stuart, D.I. | 登録日 | 2018-04-10 | 公開日 | 2018-05-23 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs. J. Med. Chem., 61, 2018
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7PS6
| Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-44 and Beta-54 Fabs | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, Beta-44 Fab heavy chain, Beta-44 Fab light chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2021-09-22 | 公開日 | 2021-12-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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7Q0G
| Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-49 and FI-3A Fabs | 分子名称: | Beta-49 Fab heavy chain, Beta-49 Fab light chain, CHLORIDE ION, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2021-10-14 | 公開日 | 2021-12-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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7Q0H
| Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-50 and Beta-54 | 分子名称: | Beta-50 Fab heavy chain, Beta-50 Fab light chain, Beta-54 Fab heavy chain, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2021-10-14 | 公開日 | 2021-12-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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7Q0I
| Crystal structure of the N-terminal domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-43 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhou, D, Ren, J, Stuart, D.I. | 登録日 | 2021-10-14 | 公開日 | 2021-12-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants. Cell Host Microbe, 30, 2022
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7Q0A
| SARS-CoV-2 Spike ectodomain with Fab FI3A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FI3A fab Light chain, ... | 著者 | Duyvesteyn, H.M.E, Ren, J, Stuart, D.I. | 登録日 | 2021-10-14 | 公開日 | 2022-02-23 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2. Theranostics, 12, 2022
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1H8T
| Echovirus 11 | 分子名称: | 12-AMINO-DODECANOIC ACID, ECHOVIRUS 11 COAT PROTEIN VP1, ECHOVIRUS 11 COAT PROTEIN VP2, ... | 著者 | Stuart, A, McKee, T, Williams, P.A, Harley, C, Stuart, D.I, Brown, T.D.K, Lea, S.M. | 登録日 | 2001-02-15 | 公開日 | 2002-07-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Determination of the Structure of a Decay Accelerating Factor-Binding Clinical Isolate of Echovirus 11 Allows Mapping of Mutants with Altered Receptor Requirements for Infection J.Virol., 76, 2002
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5MQW
| High-speed fixed-target serial virus crystallography | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Roedig, P, Ginn, H.M, Pakendorf, T, Sutton, G, Harlos, K, Walter, T.S, Meyer, J, Fischer, P, Duman, R, Vartiainen, I, Reime, B, Warmer, M, Brewster, A.S, Young, I.D, Michels-Clark, T, Sauter, N.K, Sikorsky, M, Nelson, S, Damiani, D.S, Alonso-Mori, R, Ren, J, Fry, E.E, David, C, Stuart, D.I, Wagner, A, Meents, A. | 登録日 | 2016-12-21 | 公開日 | 2017-06-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | High-speed fixed-target serial virus crystallography. Nat. Methods, 14, 2017
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5MUU
| dsRNA bacteriophage phi6 nucleocapsid | 分子名称: | Major inner protein P1, Major outer capsid protein, Packaging enzyme P4 | 著者 | Sun, Z, El Omari, K, Sun, X, Ilca, S.L, Kotecha, A, Stuart, D.I, Poranen, M.M, Huiskonen, J.T. | 登録日 | 2017-01-14 | 公開日 | 2017-03-22 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Double-stranded RNA virus outer shell assembly by bona fide domain-swapping. Nat Commun, 8, 2017
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5OAC
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5O5B
| Poliovirus type 3 (strain Saukett) stabilized virus-like particle | 分子名称: | Capsid proteins, VP1, VP2, ... | 著者 | Bahar, M.W, Kotecha, A, Fry, E.E, Stuart, D.I. | 登録日 | 2017-06-01 | 公開日 | 2017-07-12 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Plant-made polio type 3 stabilized VLPs-a candidate synthetic polio vaccine. Nat Commun, 8, 2017
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5O5P
| Poliovirus type 3 (strain Saukett) stabilized virus-like particle in complex with the pocket factor compound GPP3 | 分子名称: | 1-[5-[4-(ethoxyiminomethyl)phenoxy]-3-methyl-pentyl]-3-pyridin-4-yl-imidazol-2-one, Capsid proteins, VP4, ... | 著者 | Bahar, M.W, Kotecha, A, Fry, E.E, Stuart, D.I. | 登録日 | 2017-06-02 | 公開日 | 2017-07-12 | 最終更新日 | 2022-09-21 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Plant-made polio type 3 stabilized VLPs-a candidate synthetic polio vaccine. Nat Commun, 8, 2017
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1HI0
| RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus initiation complex | 分子名称: | DNA (5'-(*TP*TP*TP*CP*C)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. | 登録日 | 2000-12-31 | 公開日 | 2001-03-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
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1MHE
| THE HUMAN NON-CLASSICAL MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE HLA-E | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN HLA-E, PEPTIDE (VMAPRTVLL), ... | 著者 | O'Callaghan, C.A, Tormo, J, Willcox, B.E, Braud, V.B, Jakobsen, B.K, Stuart, D.I, Mcmichael, A.J, Bell, J.I, Jones, E.Y. | 登録日 | 1998-08-24 | 公開日 | 1999-03-23 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E. Mol.Cell, 1, 1998
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