1N5W
| Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Oxidized form | 分子名称: | CU(I)-S-MO(VI)(=O)OH CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | 著者 | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | 登録日 | 2002-11-07 | 公開日 | 2002-12-23 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1N63
| Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Carbon monoxide reduced state | 分子名称: | CU(I)-S-MO(IV)(=O)OH CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | 著者 | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | 登録日 | 2002-11-08 | 公開日 | 2002-12-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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1N61
| Crystal Structure of the Cu,Mo-CO Dehydrogenase (CODH); Dithionite reduced state | 分子名称: | CU(I)-S-MO(IV)(=O)OH CLUSTER, Carbon monoxide dehydrogenase large chain, Carbon monoxide dehydrogenase medium chain, ... | 著者 | Dobbek, H, Gremer, L, Kiefersauer, R, Huber, R, Meyer, O. | 登録日 | 2002-11-08 | 公開日 | 2002-12-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Catalysis at a dinuclear [CuSMo(=O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution Proc.Natl.Acad.Sci.USA, 99, 2002
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2QZW
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1TLE
| LE (LAMININ-TYPE EGF-LIKE) MODULE GIII4 IN SOLUTION AT PH 3.5 AND 290 K, NMR, 14 STRUCTURES | 分子名称: | LAMININ | 著者 | Baumgartner, R, Czisch, M, Mayer, U, Schl, E.P, Huber, R, Timpl, R, Holak, T.A. | 登録日 | 1996-01-26 | 公開日 | 1997-02-12 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the nidogen binding LE module of the laminin gamma1 chain in solution. J.Mol.Biol., 257, 1996
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1KNV
| Bse634I restriction endonuclease | 分子名称: | ACETATE ION, Bse634I restriction endonuclease, CHLORIDE ION | 著者 | Grazulis, S, Deibert, M, Rimseliene, R, Skirgaila, R, Sasnauskas, G, Lagunavicius, A, Repin, V, Urbanke, C, Huber, R, Siksnys, V. | 登録日 | 2001-12-19 | 公開日 | 2002-02-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Crystal structure of the Bse634I restriction endonuclease: comparison of two enzymes recognizing the same DNA sequence. Nucleic Acids Res., 30, 2002
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1AQX
| GLUTATHIONE S-TRANSFERASE IN COMPLEX WITH MEISENHEIMER COMPLEX | 分子名称: | 1-(S-GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXA-2,5-DIENE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE | 著者 | Prade, L, Huber, R, Manoharan, T.H, Fahl, W.E, Reuter, W. | 登録日 | 1997-08-03 | 公開日 | 1998-03-18 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of class pi glutathione S-transferase from human placenta in complex with substrate, transition-state analogue and inhibitor. Structure, 5, 1997
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1TGB
| CRYSTAL STRUCTURE OF BOVINE TRYPSINOGEN AT 1.8 ANGSTROMS RESOLUTION. II. CRYSTALLOGRAPHIC REFINEMENT, REFINED CRYSTAL STRUCTURE AND COMPARISON WITH BOVINE TRYPSIN | 分子名称: | CALCIUM ION, TRYPSINOGEN | 著者 | Bode, W, Fehlhammer, H, Huber, R. | 登録日 | 1979-03-07 | 公開日 | 1979-06-13 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of bovine trypsinogen at 1-8 A resolution. II. Crystallographic refinement, refined crystal structure and comparison with bovine trypsin. J.Mol.Biol., 111, 1977
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1WXI
| E.coli NAD Synthetase, AMP.PP | 分子名称: | ADENOSINE MONOPHOSPHATE, DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Jauch, R, Humm, A, Huber, R, Wahl, M.C. | 登録日 | 2005-01-23 | 公開日 | 2005-02-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structures of Escherichia coli NAD Synthetase with Substrates and Products Reveal Mechanistic Rearrangements J.Biol.Chem., 280, 2005
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1WXG
| E.coli NAD Synthetase, DND | 分子名称: | MAGNESIUM ION, NH(3)-dependent NAD(+) synthetase, NICOTINIC ACID ADENINE DINUCLEOTIDE | 著者 | Jauch, R, Humm, A, Huber, R, Wahl, M.C. | 登録日 | 2005-01-23 | 公開日 | 2005-02-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of Escherichia coli NAD Synthetase with Substrates and Products Reveal Mechanistic Rearrangements J.Biol.Chem., 280, 2005
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1IXO
| Enzyme-analogue substrate complex of Pyridoxine 5'-Phosphate Synthase | 分子名称: | Pyridoxine 5'-Phosphate synthase, SN-GLYCEROL-3-PHOSPHATE | 著者 | Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. | 登録日 | 2002-06-28 | 公開日 | 2003-02-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis J.MOL.BIOL., 321, 2002
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1IXQ
| Enzyme-Phosphate2 Complex of Pyridoxine 5'-Phosphate synthase | 分子名称: | PHOSPHATE ION, Pyridoxine 5'-phosphate Synthase | 著者 | Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. | 登録日 | 2002-06-28 | 公開日 | 2003-02-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis J.MOL.BIOL., 321, 2002
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1WXH
| E.coli NAD Synthetase, NAD | 分子名称: | NH(3)-dependent NAD(+) synthetase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Jauch, R, Humm, A, Huber, R, Wahl, M.C. | 登録日 | 2005-01-23 | 公開日 | 2005-02-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of Escherichia coli NAD Synthetase with Substrates and Products Reveal Mechanistic Rearrangements J.Biol.Chem., 280, 2005
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1IXP
| Enzyme-phosphate Complex of Pyridoxine 5'-Phosphate synthase | 分子名称: | PHOSPHATE ION, Pyridoxine 5'-Phosphate synthase | 著者 | Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. | 登録日 | 2002-06-28 | 公開日 | 2003-02-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis J.MOL.BIOL., 321, 2002
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1WXE
| E.coli NAD Synthetase, AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, NH(3)-dependent NAD(+) synthetase | 著者 | Jauch, R, Humm, A, Huber, R, Wahl, M.C. | 登録日 | 2005-01-23 | 公開日 | 2005-02-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of Escherichia coli NAD Synthetase with Substrates and Products Reveal Mechanistic Rearrangements J.Biol.Chem., 280, 2005
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1WXF
| E.coli NAD Synthetase | 分子名称: | NH(3)-dependent NAD(+) synthetase | 著者 | Jauch, R, Humm, A, Huber, R, Wahl, M.C. | 登録日 | 2005-01-23 | 公開日 | 2005-02-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of Escherichia coli NAD Synthetase with Substrates and Products Reveal Mechanistic Rearrangements J.Biol.Chem., 280, 2005
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3CTS
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1IXN
| Enzyme-Substrate Complex of Pyridoxine 5'-Phosphate Synthase | 分子名称: | 1-DEOXY-D-XYLULOSE-5-PHOSPHATE, Pyridoxine 5'-Phosphate Synthase, SN-GLYCEROL-3-PHOSPHATE | 著者 | Garrido-Franco, M, Laber, B, Huber, R, Clausen, T. | 登録日 | 2002-06-28 | 公開日 | 2003-02-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis J.MOL.BIOL., 321, 2002
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1VEB
| Crystal Structure of Protein Kinase A in Complex with Azepane Derivative 5 | 分子名称: | (3R,4R)-N-{4-[4-(2-FLUORO-6-HYDROXY-3-METHOXY-BENZOYL)-BENZYLOXY]-AZEPAN-3-YL}-ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... | 著者 | Breitenlechner, C.B, Wegge, T, Berillon, L, Graul, K, Marzenell, K, Friebe, W.-G, Thomas, U, Schumacher, R, Huber, R, Engh, R.A, Masjost, B. | 登録日 | 2004-03-29 | 公開日 | 2005-03-29 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Structure-based optimization of novel azepane derivatives as PKB inhibitors J.Med.Chem., 47, 2004
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1SVH
| Crystal Structure of Protein Kinase A in Complex with Azepane Derivative 8 | 分子名称: | (3R,4S)-N-(4-{TRANS-2-[4-(2-FLUORO-6-HYDROXY-3-METHOXY-BENZOYL)-PHENYL]-VINYL}-AZEPAN-3-YL)-ISONICOTINAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... | 著者 | Breitenlechner, C.B, Wegge, T, Berillon, L, Graul, K, Marzenell, K, Friebe, W.G, Thomas, U, Schumacher, R, Huber, R, Engh, R.A, Masjost, B. | 登録日 | 2004-03-29 | 公開日 | 2005-03-29 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-based optimization of novel azepane derivatives as PKB inhibitors J.Med.Chem., 47, 2004
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1YDS
| Structure of CAMP-dependent protein kinase, alpha-catalytic subunit in complex with H8 protein kinase inhibitor [N-(2-methylamino)ethyl]-5-isoquinolinesulfonamide | 分子名称: | C-AMP-DEPENDENT PROTEIN KINASE, N-[2-(METHYLAMINO)ETHYL]-5-ISOQUINOLINESULFONAMIDE, PROTEIN KINASE INHIBITOR PEPTIDE | 著者 | Engh, R.A, Girod, A, Kinzel, V, Huber, R, Bossemeyer, D. | 登録日 | 1996-07-24 | 公開日 | 1997-04-01 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity. J.Biol.Chem., 271, 1996
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1YDT
| STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH H89 PROTEIN KINASE INHIBITOR N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE | 分子名称: | C-AMP-DEPENDENT PROTEIN KINASE, N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE, PROTEIN KINASE INHIBITOR PEPTIDE | 著者 | Engh, R.A, Girod, A, Kinzel, V, Huber, R, Bossemeyer, D. | 登録日 | 1996-07-24 | 公開日 | 1997-04-01 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity. J.Biol.Chem., 271, 1996
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1YDR
| STRUCTURE OF CAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT IN COMPLEX WITH H7 PROTEIN KINASE INHIBITOR 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE | 分子名称: | 1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE, C-AMP-DEPENDENT PROTEIN KINASE, PROTEIN KINASE INHIBITOR PEPTIDE | 著者 | Engh, R.A, Girod, A, Kinzel, V, Huber, R, Bossemeyer, D. | 登録日 | 1996-07-24 | 公開日 | 1997-04-01 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of catalytic subunit of cAMP-dependent protein kinase in complex with isoquinolinesulfonyl protein kinase inhibitors H7, H8, and H89. Structural implications for selectivity. J.Biol.Chem., 271, 1996
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1TOC
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2CTS
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