2QOL
| Human EphA3 kinase and juxtamembrane region, Y596:Y602:S768G triple mutant | 分子名称: | Ephrin receptor | 著者 | Davis, T, Walker, J.R, Newman, E.M, Mackenzie, F, Butler-Cole, C, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | 登録日 | 2007-07-20 | 公開日 | 2007-08-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Autoregulation by the Juxtamembrane Region of the Human Ephrin Receptor Tyrosine Kinase A3 (EphA3). Structure, 16, 2008
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2RAN
| RAT ANNEXIN V CRYSTAL STRUCTURE: CA2+-INDUCED CONFORMATIONAL CHANGES | 分子名称: | ANNEXIN V, CALCIUM ION, SULFATE ION | 著者 | Concha, N.O, Head, J.F, Kaetzel, M.A, Dedman, J.R, Seaton, B.A. | 登録日 | 1994-09-01 | 公開日 | 1994-11-30 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Rat annexin V crystal structure: Ca(2+)-induced conformational changes. Science, 261, 1993
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7SJK
| Structure of PLS A-domain (residues 391-656) from Staphylococcus aureus | 分子名称: | CALCIUM ION, Pls Plasmin sensitive surface protein | 著者 | Clark, L, Whelan, F, Atkin, K.E, Brentnall, A.S, Dodson, E.J, Turkenburg, J.P, Potts, J.R. | 登録日 | 2021-10-18 | 公開日 | 2022-10-26 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.208 Å) | 主引用文献 | Staphylococcal Periscope proteins Aap, SasG, and Pls project noncanonical legume-like lectin adhesin domains from the bacterial surface. J.Biol.Chem., 299, 2023
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7SMH
| Structure of SASG A-domain (residues 163-419) from Staphylococcus aureus | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Surface protein G | 著者 | Atkin, K.E, Whelan, F, Brentnall, A.S, Dodson, E.J, Turkenburg, J.P, Potts, J.R. | 登録日 | 2021-10-25 | 公開日 | 2022-11-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Staphylococcal Periscope proteins Aap, SasG, and Pls project noncanonical legume-like lectin adhesin domains from the bacterial surface. J.Biol.Chem., 299, 2023
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7SSX
| Structure of human Kv1.3 | 分子名称: | POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3, Green fluorescent protein fusion | 著者 | Meyerson, J.R, Selvakumar, P. | 登録日 | 2021-11-11 | 公開日 | 2022-06-29 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. Nat Commun, 13, 2022
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7SSZ
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7SSY
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7SSV
| Structure of human Kv1.3 with Fab-ShK fusion | 分子名称: | Fab-ShK fusion, heavy chain, light chain, ... | 著者 | Meyerson, J.R, Selvakumar, P, Smider, V, Huang, R. | 登録日 | 2021-11-11 | 公開日 | 2022-06-29 | 最終更新日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. Nat Commun, 13, 2022
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1PAA
| STRUCTURE OF A HISTIDINE-X4-HISTIDINE ZINC FINGER DOMAIN: INSIGHTS INTO ADR1-UAS1 PROTEIN-DNA RECOGNITION | 分子名称: | YEAST TRANSCRIPTION FACTOR ADR1, ZINC ION | 著者 | Bernstein, B.E, Hoffman, R.C, Horvath, S.J, Herriott, J.R, Klevit, R.E. | 登録日 | 1994-07-15 | 公開日 | 1994-10-15 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a histidine-X4-histidine zinc finger domain: insights into ADR1-UAS1 protein-DNA recognition. Biochemistry, 33, 1994
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7SP2
| Structure of PLS A-domain (residues 391-656; 513-518 deletion mutant) from Staphylococcus aureus | 分子名称: | CALCIUM ION, Plasmin Sensitive Protein Pls | 著者 | Clark, L, Whelan, F, Atkin, K.E, Brentnall, A.S, Dodson, E.J, Turkenburg, J.P, Potts, J.R. | 登録日 | 2021-11-02 | 公開日 | 2022-11-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structure of PLS A-domain (residues 391-65) from Staphylococcus aureus Not Published
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1PC9
| Crystal Structure of BnSP-6, a Lys49-Phospholipase A2 | 分子名称: | BnSP-6 | 著者 | Magro, A.J, Soares, A.M, Giglio, J.R, Fontes, M.R.M. | 登録日 | 2003-05-16 | 公開日 | 2004-06-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A(2): quaternary structure and inhibition mechanism insights. Biochem.Biophys.Res.Commun., 311, 2003
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7TN0
| SARS-CoV-2 Omicron RBD in complex with human ACE2 and S304 Fab and S309 Fab | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | McCallum, M, Czudnochowski, N, Nix, J.C, Croll, T.I, SSGCID, Dillen, J.R, Snell, G, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2022-01-20 | 公開日 | 2022-02-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement. Science, 375, 2022
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7TIO
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7TIR
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7TIP
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7TIS
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7TIQ
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1OXA
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7U4A
| Crystal Structure of Zika virus xrRNA1 mutant | 分子名称: | MAGNESIUM ION, RNA (70-MER) | 著者 | Thompson, R.D, Carbaugh, D.L, Nielsen, J.R, Witt, C, Meganck, R.M, Rangadurai, A, Zhao, B, Bonin, J.P, Nathan, N.T, Marzluff, W.F, Frank, A.T, Lazear, H.M, Zhang, Q. | 登録日 | 2022-02-28 | 公開日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Dynamic Basis of Xrn1 Resistance in Mosquito-borne Flavivirus RNA To Be Published
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7TVP
| Viral AMG chitosanase V-Csn, E157Q mutant, chitotriose complex | 分子名称: | 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, GLYCEROL, Viral chitosanase V-Csn E157Q mutant chitotriose complex | 著者 | Smith, C.A, Wu, R, Buchko, G.W, Cort, J.R, Hofmockel, K.S, Jansson, J.K. | 登録日 | 2022-02-05 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Structural characterization of a soil viral auxiliary metabolic gene product - a functional chitosanase. Nat Commun, 13, 2022
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7TVM
| Viral AMG chitosanase V-Csn, apo structure, crystal form 2 | 分子名称: | 1,2-ETHANEDIOL, Viral chitosanase V-Csn | 著者 | Smith, C.A, Wu, R, Buchko, G.W, Cort, J.R, Hofmockel, K.S, Jansson, J.K. | 登録日 | 2022-02-05 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structural characterization of a soil viral auxiliary metabolic gene product - a functional chitosanase. Nat Commun, 13, 2022
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7UYW
| Crystal structure of JAK2 kinase domain in complex with compound 30 | 分子名称: | 2-(2,6-difluorophenyl)-4-[4-(pyrrolidine-1-carbonyl)anilino]-5H-pyrrolo[3,4-b]pyridin-5-one, Tyrosine-protein kinase JAK2 | 著者 | Toms, A.V, Leit, S, Greenwood, J.R, Mondal, S, Carriero, S, Dahlgren, M, Harriman, G.C, Kennedy-Smith, J.J, Kapeller, R, Lawson, J.P, Romero, D.L, Shelley, M, Wester, R.T, Westlin, W, Mc Elwee, J.J, Miao, W, Edmondson, S.D, Massee, C.E. | 登録日 | 2022-05-07 | 公開日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Potent and selective TYK2-JH1 inhibitors highly efficacious in rodent model of psoriasis. Bioorg.Med.Chem.Lett., 73, 2022
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7UYT
| Crystal structure of TYK2 kinase domain in complex with compound 25 | 分子名称: | 6-{[(2M)-2-(2-chloro-6-fluorophenyl)-5-oxo-5H-pyrrolo[3,4-b]pyridin-4-yl]amino}-N-ethylpyridine-3-carboxamide, Non-receptor tyrosine-protein kinase TYK2 | 著者 | Toms, A.V, Leit, S, Greenwood, J.R, Mondal, S, Carriero, S, Dahlgren, M, Harriman, G.C, Kennedy-Smith, J.J, Kapeller, R, Lawson, J.P, Romero, D.L, Shelley, M, Wester, R.T, Westlin, W, Mc Elwee, J.J, Miao, W, Edmondson, S.D, Massee, C.E. | 登録日 | 2022-05-07 | 公開日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Potent and selective TYK2-JH1 inhibitors highly efficacious in rodent model of psoriasis. Bioorg.Med.Chem.Lett., 73, 2022
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7UYV
| Crystal structure of JAK3 kinase domain in complex with compound 25 | 分子名称: | 6-{[(2M)-2-(2-chloro-6-fluorophenyl)-5-oxo-5H-pyrrolo[3,4-b]pyridin-4-yl]amino}-N-ethylpyridine-3-carboxamide, CHLORIDE ION, Tyrosine-protein kinase JAK3 | 著者 | Toms, A.V, Leit, S, Greenwood, J.R, Mondal, S, Carriero, S, Dahlgren, M, Harriman, G.C, Kennedy-Smith, J.J, Kapeller, R, Lawson, J.P, Romero, D.L, Shelley, M, Wester, R.T, Westlin, W, Mc Elwee, J.J, Miao, W, Edmondson, S.D, Massee, C.E. | 登録日 | 2022-05-07 | 公開日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Potent and selective TYK2-JH1 inhibitors highly efficacious in rodent model of psoriasis. Bioorg.Med.Chem.Lett., 73, 2022
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7UYS
| Crystal structure of TYK2 kinase domain in complex with compound 16 | 分子名称: | 2-(2,6-difluorophenyl)-4-(4-methoxyanilino)-5H-pyrrolo[3,4-d]pyrimidin-5-one, Non-receptor tyrosine-protein kinase TYK2 | 著者 | Toms, A.V, Leit, S, Greenwood, J.R, Mondal, S, Carriero, S, Dahlgren, M, Harriman, G.C, Kennedy-Smith, J.J, Kapeller, R, Lawson, J.P, Romero, D.L, Shelley, M, Wester, R.T, Westlin, W, Mc Elwee, J.J, Miao, W, Edmondson, S.D, Massee, C.E. | 登録日 | 2022-05-07 | 公開日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Potent and selective TYK2-JH1 inhibitors highly efficacious in rodent model of psoriasis. Bioorg.Med.Chem.Lett., 73, 2022
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