5WVN
 
 | | Crystal structure of MBS-BaeS fusion protein | | 分子名称: | Maltose-binding periplasmic protein,Two-component system sensor kinase, SULFATE ION | | 著者 | Wang, W, Zhang, Y, Ran, T, Xu, D. | | 登録日 | 2016-12-26 | | 公開日 | 2018-01-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of the sensor domain of BaeS from Serratia marcescens FS14
Proteins, 85, 2017
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3SV5
 | | Engineered medium-affinity halide-binding protein derived from YFP: iodide complex | | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, Green fluorescent protein, ... | | 著者 | Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W. | | 登録日 | 2011-07-12 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation.
J.Neurosci., 33, 2013
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3ST0
 | | Engineered medium-affinity halide-binding protein derived from YFP: halide-free | | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, Green fluorescent protein | | 著者 | Wang, W, Grimley, J.S, Beese, L.S, Hellinga, H.W. | | 登録日 | 2011-07-08 | | 公開日 | 2012-07-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | | 主引用文献 | Visualization of Synaptic Inhibition with an Optogenetic Sensor Developed by Cell-Free Protein Engineering Automation.
J.Neurosci., 33, 2013
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2MBE
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7EOZ
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8GYN
 | | zebrafish TIPE1 strucutre in complex with PE | | 分子名称: | Tumor necrosis factor alpha-induced protein 8-like protein 1, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | 著者 | Wang, W, Cao, S.J. | | 登録日 | 2022-09-23 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Structural insight into TIPE1 functioning as a lipid transfer protein.
J.Biomol.Struct.Dyn., 41, 2023
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7CK6
 | | Protein translocase of mitochondria | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Mitochondrial import receptor subunit TOM22 homolog, Mitochondrial import receptor subunit TOM40 homolog, ... | | 著者 | Yang, M, Wang, W, Zhang, L, Chen, X. | | 登録日 | 2020-07-15 | | 公開日 | 2020-11-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Atomic structure of human TOM core complex.
Cell Discov, 6, 2020
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2VG0
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2VG2
 | | Rv2361 with IPP | | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CHLORIDE ION, DIPHOSPHATE, ... | | 著者 | Naismith, J.H, Wang, W, Dong, C. | | 登録日 | 2007-11-07 | | 公開日 | 2007-11-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
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2VG3
 | | Rv2361 with citronellyl pyrophosphate | | 分子名称: | CHLORIDE ION, GERANYL DIPHOSPHATE, GLYCEROL, ... | | 著者 | Naismith, J.H, Wang, W, Dong, C. | | 登録日 | 2007-11-08 | | 公開日 | 2008-05-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
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2VG4
 | | Rv2361 native | | 分子名称: | UNDECAPRENYL PYROPHOSPHATE SYNTHETASE | | 著者 | Naismith, J.H, Wang, W, Dong, C. | | 登録日 | 2007-11-08 | | 公開日 | 2007-11-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
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2VG1
 | | Rv1086 E,E-farnesyl diphosphate complex | | 分子名称: | FARNESYL DIPHOSPHATE, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Naismith, J.H, Wang, W, Dong, C. | | 登録日 | 2007-11-07 | | 公開日 | 2007-11-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
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2VFW
 | | Rv1086 native | | 分子名称: | SHORT-CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHETASE, SULFATE ION | | 著者 | Naismith, J.H, Wang, W, Dong, C. | | 登録日 | 2007-11-05 | | 公開日 | 2007-11-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The structural basis of chain length control in Rv1086.
J. Mol. Biol., 381, 2008
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1KKB
 | | Complex of Escherichia coli Adenylosuccinate Synthetase with IMP and Hadacidin | | 分子名称: | Adenylosuccinate Synthetase, HADACIDIN, INOSINIC ACID | | 著者 | Hou, Z, Wang, W, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2001-12-06 | | 公開日 | 2002-03-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | IMP Alone Organizes the Active Site of Adenylosuccinate Synthetase from Escherichia coli.
J.Biol.Chem., 277, 2002
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1KKF
 | | Complex of E. coli Adenylosuccinate Synthetase with IMP, Hadacidin, Pyrophosphate, and Mg | | 分子名称: | Adenylosuccinate Synthetase, DIPHOSPHATE, HADACIDIN, ... | | 著者 | Hou, Z, Wang, W, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2001-12-07 | | 公開日 | 2002-03-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | IMP Alone Organizes the Active Site of Adenylosuccinate Synthetase from Escherichia coli.
J.Biol.Chem., 277, 2002
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1KJX
 | | IMP Complex of E. Coli Adenylosuccinate Synthetase | | 分子名称: | Adenylosuccinate Synthetase, INOSINIC ACID | | 著者 | Hou, Z, Wang, W, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2001-12-05 | | 公開日 | 2002-03-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | IMP Alone Organizes the Active Site of Adenylosuccinate Synthetase from Escherichia coli.
J.Biol.Chem., 277, 2002
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4DSO
 | | Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, BENZAMIDINE, GLYCEROL, ... | | 著者 | Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W. | | 登録日 | 2012-02-19 | | 公開日 | 2012-04-04 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4DSU
 | | Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity | | 分子名称: | BENZIMIDAZOLE, GTPase KRas, isoform 2B, ... | | 著者 | Oh, A, Maurer, T, Garrenton, L.S, Pitts, K, Anderson, D.J, Skelton, N.J, Fauber, B.P, Pan, B, Malek, S, Stokoe, D, Ludlam, M, Bowman, K.K, Wu, J, Giannetti, A.M, Starovasnik, M.A, Mellman, I, Jackson, P.K, Ruldolph, J, Fang, G, Wang, W. | | 登録日 | 2012-02-19 | | 公開日 | 2012-04-04 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.
Proc.Natl.Acad.Sci.USA, 109, 2012
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8YB4
 | | Pfr conformer of Arabidopsis thaliana phytochrome B in complex with phytochrome-interacting factor 6 | | 分子名称: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, phytochrome B, phytochrome-interacting factor 6 | | 著者 | Wang, Z, Wang, W, Zhao, D, Song, Y, Xu, B, Zhao, J, Wang, J. | | 登録日 | 2024-02-11 | | 公開日 | 2024-10-02 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Light-induced remodeling of phytochrome B enables signal transduction by phytochrome-interacting factor.
Cell, 2024
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9IUZ
 | | Constitutively active mutant(Y276H) of Arabidopsis phytochrome B(phyB) in complex with phytochrome-interacting factor 6(PIF6) | | 分子名称: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome B, Phytochrome-interacting factor 6 | | 著者 | Wang, Z, Wang, W, Zhao, D, Song, Y, Xu, B, Zhao, J, Wang, J. | | 登録日 | 2024-07-22 | | 公開日 | 2024-10-02 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Light-induced remodeling of phytochrome B enables signal transduction by phytochrome-interacting factor.
Cell, 2024
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8XLH
 | | Structure of chimeric RyR-I4657M/G4819E | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ... | | 著者 | Lin, L, Wang, C, Wang, W, Jiang, H, Yuchi, Z. | | 登録日 | 2023-12-26 | | 公開日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Cryo-EM structures of ryanodine receptors and diamide insecticides reveal the mechanisms of selectivity and resistance.
Nat Commun, 15, 2024
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8XLF
 | | Structure of chimeric RyR | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ... | | 著者 | Lin, L, Wang, C, Wang, W, Jiang, H, Yuchi, Z. | | 登録日 | 2023-12-25 | | 公開日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Cryo-EM structures of ryanodine receptors and diamide insecticides reveal the mechanisms of selectivity and resistance.
Nat Commun, 15, 2024
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8XKH
 | | Structure of chimeric RyR Complex with tetraniliprole | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ... | | 著者 | Lin, L, Wang, C, Wang, W, Jiang, H, Yuchi, Z. | | 登録日 | 2023-12-23 | | 公開日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | Cryo-EM structures of ryanodine receptors and diamide insecticides reveal the mechanisms of selectivity and resistance.
Nat Commun, 15, 2024
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8Y40
 | | Structure of chimeric RyR-I4657M/G4819E complex with chlorantraniliprole | | 分子名称: | 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ... | | 著者 | Lin, L, Wang, C, Wang, W, Jiang, H, Yuchi, Z. | | 登録日 | 2024-01-29 | | 公開日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Cryo-EM structures of ryanodine receptors and diamide insecticides reveal the mechanisms of selectivity and resistance.
Nat Commun, 15, 2024
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4M6P
 | | Identification of Amides Derived From 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) | | 分子名称: | N-[4-(phenylsulfonyl)benzyl]-2H-pyrazolo[3,4-b]pyridine-5-carboxamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION | | 著者 | Giannetti, A.M, Zheng, X, Skelton, N, Wang, W, Bravo, B, Feng, Y, Gunzner-Toste, J, Ho, Y, Hua, R, Wang, C, Zhao, Q, Liederer, B.M, Liu, Y, O'Brien, T, Oeh, J, Sampath, D, Shen, Y, Wang, L, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhao, G, Dragovich, P.S. | | 登録日 | 2013-08-10 | | 公開日 | 2013-09-25 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT).
Bioorg.Med.Chem.Lett., 23, 2013
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