7QB2
| Pim1 in complex with (E)-4-((6-amino-1-methyl-2-oxoindolin-3-ylidene)methyl)benzoic acid and Pimtide | 分子名称: | 4-[(E)-(6-azanyl-1-methyl-2-oxidanylidene-indol-3-ylidene)methyl]benzoic acid, GLYCEROL, Pimtide, ... | 著者 | Hochban, P.M.M, Heine, A, Diederich, W.E. | 登録日 | 2021-11-18 | 公開日 | 2022-11-30 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Pose, duplicate, then elaborate: Steps towards increased affinity for inhibitors targeting the specificity surface of the Pim-1 kinase. Eur.J.Med.Chem., 245, 2023
|
|
7QFM
| Pim1 in complex with (E)-4-((2-oxoindolin-3-ylidene)methyl)benzoic acid and Pimtide | 分子名称: | 4-[(~{E})-(2-oxidanylidene-1~{H}-indol-3-ylidene)methyl]benzoic acid, GLYCEROL, Pimtide, ... | 著者 | Hochban, P.M.M, Heine, A, Diederich, W.E. | 登録日 | 2021-12-06 | 公開日 | 2022-12-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Pose, duplicate, then elaborate: Steps towards increased affinity for inhibitors targeting the specificity surface of the Pim-1 kinase. Eur.J.Med.Chem., 245, 2023
|
|
7KKU
| X-ray Counterpart to Neutron Structure of Oxidized Human MnSOD | 分子名称: | MANGANESE (III) ION, PHOSPHATE ION, Superoxide dismutase [Mn], ... | 著者 | Azadmanesh, J, Lutz, W.E, Coates, L, Weiss, K.L, Borgstahl, G.E.O. | 登録日 | 2020-10-28 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase. Nat Commun, 12, 2021
|
|
7KLB
| X-ray Counterpart to Neutron Structure of Reduced Human MnSOD | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, POTASSIUM ION, ... | 著者 | Azadmanesh, J, Lutz, W.E, Coates, L, Weiss, K.L, Borgstahl, G.E.O. | 登録日 | 2020-10-29 | 公開日 | 2021-04-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase. Nat Commun, 12, 2021
|
|
7KKW
| Neutron structure of Reduced Human MnSOD | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial, ... | 著者 | Azadmanesh, J, Lutz, W.E, Coates, L, Weiss, K.L, Borgstahl, G.E.O. | 登録日 | 2020-10-28 | 公開日 | 2021-04-21 | 最終更新日 | 2024-04-10 | 実験手法 | NEUTRON DIFFRACTION (2.3 Å) | 主引用文献 | Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase. Nat Commun, 12, 2021
|
|
7KKS
| Neutron structure of Oxidized Human MnSOD | 分子名称: | MANGANESE (III) ION, Superoxide dismutase [Mn], mitochondrial | 著者 | Azadmanesh, J, Lutz, W.E, Coates, L, Weiss, K.L, Borgstahl, G.E.O. | 登録日 | 2020-10-28 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | NEUTRON DIFFRACTION (2.2 Å) | 主引用文献 | Direct detection of coupled proton and electron transfers in human manganese superoxide dismutase. Nat Commun, 12, 2021
|
|
7L4L
| Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabF, and C8-crypto Acyl Carrier Protein, AcpP | 分子名称: | 3-oxoacyl-[acyl-carrier-protein] synthase 2, Acyl carrier protein, SODIUM ION, ... | 著者 | Mindrebo, J.T, Chen, A, Kim, W.E, Burkart, M.D, Noel, J.P. | 登録日 | 2020-12-19 | 公開日 | 2021-09-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structure and Mechanistic Analyses of the Gating Mechanism of Elongating Ketosynthases Acs Catalysis, 11, 2021
|
|
7L4E
| Crosslinked Crystal Structure of Type II Fatty Acid Synthase Ketosynthase, FabF, and C16:1-crypto Acyl Carrier Protein, AcpP | 分子名称: | 1,2-ETHANEDIOL, 3-oxoacyl-[acyl-carrier-protein] synthase 2, Acyl carrier protein, ... | 著者 | Mindrebo, J.T, Chen, A, Kim, W.E, Burkart, M.D, Noel, J.P. | 登録日 | 2020-12-18 | 公開日 | 2021-10-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and Mechanistic Analyses of the Gating Mechanism of Elongating Ketosynthases Acs Catalysis, 11, 2021
|
|
3UHU
| HBI (M37A) deoxy | 分子名称: | Globin-1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ren, Z, Srajer, V, Knapp, J.E, Royer Jr, W.E. | 登録日 | 2011-11-03 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3UH5
| HBI (L36F) CO bound | 分子名称: | CARBON MONOXIDE, Globin-1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ren, Z, Srajer, V, Knapp, J.E, Royer Jr, W.E. | 登録日 | 2011-11-03 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3UHH
| HBI (M37A) CO bound | 分子名称: | CARBON MONOXIDE, Globin-1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ren, Z, Srajer, V, Knapp, J.E, Royer Jr, W.E. | 登録日 | 2011-11-03 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3UHR
| HBI (L36F) deoxy | 分子名称: | Globin-1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ren, Z, Srajer, V, Knapp, J.E, Royer Jr, W.E. | 登録日 | 2011-11-03 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3UHD
| HBI (N100A) CO bound | 分子名称: | CARBON MONOXIDE, Globin-1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ren, Z, Srajer, V, Knapp, J.E, Royer Jr, W.E. | 登録日 | 2011-11-03 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3UHQ
| HBI (L36A) deoxy | 分子名称: | Globin-1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ren, Z, Srajer, V, Knapp, J.E, Royer Jr, W.E. | 登録日 | 2011-11-03 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3UHV
| HBI (M37V,L73I) deoxy | 分子名称: | Globin-1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ren, Z, Srajer, V, Knapp, J.E, Royer Jr, W.E. | 登録日 | 2011-11-03 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
1INN
| CRYSTAL STRUCTURE OF D. RADIODURANS LUXS, P21 | 分子名称: | AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, METHIONINE, ZINC ION | 著者 | Lewis, H.A, Furlong, E.B, Bergseid, M.G, Sanderson, W.E, Buchanan, S.G. | 登録日 | 2001-05-14 | 公開日 | 2001-06-08 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs. Structure, 9, 2001
|
|
1J6X
| CRYSTAL STRUCTURE OF HELICOBACTER PYLORI LUXS | 分子名称: | AUTOINDUCER-2 PRODUCTION PROTEIN LUXS, METHIONINE, ZINC ION | 著者 | Lewis, H.A, Furlong, E.B, Bergseid, M.G, Sanderson, W.E, Buchanan, S.G. | 登録日 | 2001-05-14 | 公開日 | 2001-06-08 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | A structural genomics approach to the study of quorum sensing: crystal structures of three LuxS orthologs. Structure, 9, 2001
|
|
3UGY
| HBI (F80Y) CO bound | 分子名称: | CARBON MONOXIDE, Globin-1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ren, Z, Srajer, V, Knapp, J.E, Royer Jr, W.E. | 登録日 | 2011-11-03 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3UI0
| HBI (T72G) deoxy | 分子名称: | Globin-1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ren, Z, Srajer, V, Knapp, J.E, Royer Jr, W.E. | 登録日 | 2011-11-03 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3UHE
| HBI (M37V,L73I) CO bound | 分子名称: | CARBON MONOXIDE, Globin-1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ren, Z, Srajer, V, Knapp, J.E, Royer Jr, W.E. | 登録日 | 2011-11-03 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
3UHS
| HBI (L36M) deoxy | 分子名称: | Globin-1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Ren, Z, Srajer, V, Knapp, J.E, Royer Jr, W.E. | 登録日 | 2011-11-03 | 公開日 | 2011-12-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
1QSE
| STRUCTURE OF HUMAN A6-TCR BOUND TO HLA-A2 COMPLEXED WITH ALTERED HTLV-1 TAX PEPTIDE V7R | 分子名称: | PROTEIN (MHC class I HLA-A), PROTEIN (beta-2 microglobulin), PROTEIN (human T-Cell receptor), ... | 著者 | Ding, Y.H, Baker, B.M, Garboczi, D.N, Biddison, W.E, Wiley, D.C. | 登録日 | 1999-06-21 | 公開日 | 1999-12-21 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical. Immunity, 11, 1999
|
|
1QSF
| STRUCTURE OF A6-TCR BOUND TO HLA-A2 COMPLEXED WITH ALTERED HTLV-1 TAX PEPTIDE Y8A | 分子名称: | BETA-2 MICROGLOBULIN, HUMAN T-CELL RECEPTOR, MHC CLASS I HLA-A, ... | 著者 | Ding, Y.H, Baker, B.M, Garboczi, D.N, Biddison, W.E, Wiley, D.C. | 登録日 | 1999-06-21 | 公開日 | 1999-12-21 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical. Immunity, 11, 1999
|
|
3G4W
| Ligand migration and cavities within scapharca dimeric hemoglobin: wild type with co bound to heme and chlorobenzene bound to the XE4 cavity | 分子名称: | CARBON MONOXIDE, GLOBIN-1, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Knapp, J.E, Pahl, R, Cohen, J, Nichols, J.C, Schulten, K, Gibson, Q.H, Srajer, V, Royer Jr, W.E. | 登録日 | 2009-02-04 | 公開日 | 2009-12-01 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Ligand migration and cavities within Scapharca Dimeric HbI: studies by time-resolved crystallo-graphy, Xe binding, and computational analysis. Structure, 17, 2009
|
|
5W87
| |