5IL8
 
 | | Tobacco 5-epi-aristolochene synthase with MOPSO buffer molecule and Ca2+ ions | | 分子名称: | (2R)-2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonic acid, (2S)-2-hydroxy-3-(morpholin-4-yl)propane-1-sulfonic acid, 5-epi-aristolochene synthase, ... | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5ILJ
 | | Tobacco 5-epi-aristolochene synthase with BIS-TRIS buffer molecule | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-epi-aristolochene synthase | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-04 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5ILZ
 | | Tobacco 5-epi-aristolochene synthase with BIS-TRIS propane (BTP) buffer molecule | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-epi-aristolochene synthase | | 著者 | Koo, H.J, Louie, G.V, Xu, Y, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-05 | | 公開日 | 2017-03-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Small-molecule buffer components can directly affect terpene-synthase activity by interacting with the substrate-binding site of the enzyme
To Be Published
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5IK0
 | | Tobacco 5-epi-aristolochene synthase with FPP | | 分子名称: | 5-epi-aristolochene synthase, FARNESYL DIPHOSPHATE, MAGNESIUM ION | | 著者 | Koo, H.J, Xu, Y, Louie, G.V, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-03 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants.
J.Antibiot., 69, 2016
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5IK9
 | | Tobacco 5-epi-aristolochene with farnesyl monophosphate | | 分子名称: | (2E,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl dihydrogen phosphate, 5-epi-aristolochene synthase, MAGNESIUM ION | | 著者 | Koo, H.J, Xu, Y, Louie, G.V, Bowman, M, Noel, J.P. | | 登録日 | 2016-03-03 | | 公開日 | 2016-10-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants.
J.Antibiot., 69, 2016
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1U0W
 | | An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: 18xCHS+resveratrol Structure | | 分子名称: | Chalcone synthase 2, RESVERATROL | | 著者 | Austin, M.B, Bowman, M.E, Ferrer, J.-L, Schroder, J, Noel, J.P. | | 登録日 | 2004-07-14 | | 公開日 | 2004-10-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases
Chem.Biol., 11, 2004
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1U0V
 | | An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization of Specificity of Type III Polyketide Synthases: 18xCHS structure | | 分子名称: | Chalcone synthase 2 | | 著者 | Austin, M.B, Bowman, M.E, Ferrer, J.-L, Schroder, J, Noel, J.P. | | 登録日 | 2004-07-14 | | 公開日 | 2004-10-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases
Chem.Biol., 11, 2004
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1U0M
 | | Crystal Structure of 1,3,6,8-Tetrahydroxynaphthalene Synthase (THNS) from Streptomyces coelicolor A3(2): a Bacterial Type III Polyketide Synthase (PKS) Provides Insights into Enzymatic Control of Reactive Polyketide Intermediates | | 分子名称: | GLYCEROL, POLYETHYLENE GLYCOL (N=34), putative polyketide synthase | | 著者 | Austin, M.B, Izumikawa, M, Bowman, M.E, Udwary, D.W, Ferrer, J.L, Moore, B.S, Noel, J.P. | | 登録日 | 2004-07-13 | | 公開日 | 2004-09-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates
J.Biol.Chem., 279, 2004
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1Y6I
 | | Synechocystis GUN4 | | 分子名称: | Mg-chelatase cofactor GUN4 | | 著者 | Verdecia, M.A, Larkin, R.M, Ferrer, J.L, Riek, R, Chory, J, Noel, J.P. | | 登録日 | 2004-12-06 | | 公開日 | 2005-05-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structure of the Mg-chelatase cofactor GUN4 reveals a novel hand-shaped fold for porphyrin binding
Plos Biol., 3, 2005
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1YQD
 | | Sinapyl Alcohol Dehydrogenase complexed with NADP+ | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Bomati, E.K, Noel, J.P. | | 登録日 | 2005-02-01 | | 公開日 | 2005-07-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural and Kinetic Basis for Substrate Selectivity in Populus tremuloides Sinapyl Alcohol Dehydrogenase.
Plant Cell, 17, 2005
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1YQX
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1YFO
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1ZGA
 | | Crystal structure of isoflavanone 4'-O-methyltransferase complexed with (+)-6a-hydroxymaackiain | | 分子名称: | (6AR,12AR)-6H-[1,3]DIOXOLO[5,6][1]BENZOFURO[3,2-C]CHROMENE-3,6A(12AH)-DIOL, Isoflavanone 4'-O-methyltransferase', S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Liu, C.-J, Deavours, B.E, Richard, S, Ferrer, J.-L, Dixon, R.A, Noel, J.P. | | 登録日 | 2005-04-20 | | 公開日 | 2006-08-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural basis for dual functionality of isoflavonoid O-methyltransferases in the evolution of plant defense responses.
Plant Cell, 18, 2006
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1ZB6
 | | Co-Crystal Structure of ORF2 an Aromatic Prenyl Transferase from Streptomyces sp. strain cl190 complexed with GSPP and 1,6-dihydroxynaphtalene | | 分子名称: | 1,6-DIHYDROXY NAPHTHALENE, Aromatic prenyltransferase, GERANYL S-THIOLODIPHOSPHATE, ... | | 著者 | Kuzuyama, T, Noel, J.P, Richard, S.B. | | 登録日 | 2005-04-07 | | 公開日 | 2005-06-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products.
Nature, 435, 2005
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1ZCN
 | | human Pin1 Ng mutant | | 分子名称: | PENTAETHYLENE GLYCOL, PHOSPHATE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Jager, M, Zhang, Y, Nguyen, H, Dendel, G, Bowman, M.E, Gruebele, M, Noel, J.P, Kelly, J.W. | | 登録日 | 2005-04-12 | | 公開日 | 2006-06-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-function-folding relationship in a WW domain.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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1ZDW
 | | Co-crystal structure of Orf2 an aromatic prenyl transferase from Streptomyces sp. strain CL190 complexed with GSPP and Flaviolin | | 分子名称: | Aromatic prenyltransferase, FLAVIOLIN, GERANYL S-THIOLODIPHOSPHATE, ... | | 著者 | Kuzuyama, T, Noel, J.P, Richard, S.B. | | 登録日 | 2005-04-15 | | 公開日 | 2005-06-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products.
Nature, 435, 2005
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1ZG3
 | | Crystal structure of the isoflavanone 4'-O-methyltransferase complexed with SAH and 2,7,4'-trihydroxyisoflavanone | | 分子名称: | (2S,3R)-2,7-DIHYDROXY-3-(4-HYDROXYPHENYL)-2,3-DIHYDRO-4H-CHROMEN-4-ONE, S-ADENOSYL-L-HOMOCYSTEINE, isoflavanone 4'-O-methyltransferase | | 著者 | Liu, C.-J, Deavours, B.E, Richard, S, Ferrer, J.-L, Dixon, R.A, Noel, J.P. | | 登録日 | 2005-04-20 | | 公開日 | 2006-08-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural basis for dual functionality of isoflavonoid O-methyltransferases in the evolution of plant defense responses.
Plant Cell, 18, 2006
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1ZDY
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1ZHF
 | | Crystal structure of selenomethionine substituted isoflavanone 4'-O-methyltransferase | | 分子名称: | Isoflavanone 4'-O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Liu, C.-J, Deavours, B.E, Richard, S, Ferrer, J.-L, Dixon, R.A, Noel, J.P. | | 登録日 | 2005-04-25 | | 公開日 | 2006-08-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for dual functionality of isoflavonoid O-methyltransferases in the evolution of plant defense responses.
Plant Cell, 18, 2006
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1ZCW
 | | Co-crystal structure of Orf2 an aromatic prenyl transferase from Streptomyces sp. strain CL190 complexed with GPP | | 分子名称: | Aromatic prenyltransferase, GERANYL DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Kuzuyama, T, Noel, J.P, Richard, S.B. | | 登録日 | 2005-04-13 | | 公開日 | 2005-06-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products.
Nature, 435, 2005
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1ZGD
 | | Chalcone Reductase Complexed With NADP+ at 1.7 Angstrom Resolution | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, chalcone reductase | | 著者 | Bomati, E.K, Austin, M.B, Bowman, M.E, Dixon, R.A, Noel, J.P. | | 登録日 | 2005-04-21 | | 公開日 | 2005-06-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural elucidation of chalcone reductase and implications for deoxychalcone biosynthesis
J.Biol.Chem., 280, 2005
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1ZGJ
 | | Crystal structure of isoflavanone 4'-O-methyltransferase complexed with (+)-pisatin | | 分子名称: | (6AR,12AR)-3-(HYDROXYMETHYL)-6H-[1,3]DIOXOLO[5,6][1]BENZOFURO[3,2-C]CHROMEN-6A(12AH)-OL, Isoflavanone 4'-O-methyltransferase', S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Liu, C.-J, Deavours, B.E, Richard, S, Ferrer, J.-L, Dixon, R.A, Noel, J.P. | | 登録日 | 2005-04-21 | | 公開日 | 2006-08-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for dual functionality of isoflavonoid O-methyltransferases in the evolution of plant defense responses.
Plant Cell, 18, 2006
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1P15
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1OSH
 | | A Chemical, Genetic, and Structural Analysis of the nuclear bile acid receptor FXR | | 分子名称: | Bile acid receptor, METHYL 3-{3-[(CYCLOHEXYLCARBONYL){[4'-(DIMETHYLAMINO)BIPHENYL-4-YL]METHYL}AMINO]PHENYL}ACRYLATE | | 著者 | Downes, M, Verdecia, M.A, Roecker, A.J, Hughes, R, Hogenesch, J.B, Kast-Woelbern, H.R, Bowman, M.E, Ferrer, J.-L, Anisfeld, A.M, Edwards, P.A, Rosenfeld, J.M, Alvarez, J.G.A, Noel, J.P, Nicolaou, K.C, Evans, R.M. | | 登録日 | 2003-03-19 | | 公開日 | 2003-09-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR
Mol.Cell, 11, 2003
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1P13
 | | Crystal Structure of the Src SH2 Domain Complexed with Peptide (SDpYANFK) | | 分子名称: | CACODYLATE ION, Peptide, Proto-oncogene tyrosine-protein kinase Src | | 著者 | Sonnenburg, E.D, Bilwes, A, Hunter, T, Noel, J.P. | | 登録日 | 2003-04-11 | | 公開日 | 2003-08-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region.
Biochemistry, 42, 2003
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