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7TDM
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BU of 7tdm by Molmil
CryoEM Structure of sFab COP-2 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain
分子名称: COP-2 Fab Heavy chain, COP-2 Fab Light chain, Claudin-4, ...
著者Vecchio, A.J.
登録日2022-01-01
公開日2022-02-09
最終更新日2024-01-17
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
J.Biol.Chem., 298, 2022
3PJS
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BU of 3pjs by Molmil
Mechanism of Activation Gating in the Full-Length KcsA K+ Channel
分子名称: FAB heavy chain, FAB light chain, Voltage-gated potassium channel
著者Uysal, S, Cuello, L.G, Kossiakoff, A, Perozo, E.
登録日2010-11-10
公開日2011-07-06
最終更新日2011-08-03
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Mechanism of activation gating in the full-length KcsA K+ channel.
Proc.Natl.Acad.Sci.USA, 108, 2011
6E1M
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BU of 6e1m by Molmil
Structure of AtTPC1(DDE) reconstituted in saposin A
分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ...
著者Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M.
登録日2018-07-10
公開日2018-09-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1N
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BU of 6e1n by Molmil
Structure of AtTPC1(DDE) in state 1
分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ...
著者Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M.
登録日2018-07-10
公開日2018-09-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1P
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BU of 6e1p by Molmil
Structure of AtTPC1(DDE) in state 2
分子名称: CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1
著者Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M.
登録日2018-07-10
公開日2018-09-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6E1K
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BU of 6e1k by Molmil
Structure of AtTPC1(DDE) reconstituted in saposin A with cat06 Fab
分子名称: CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1, ...
著者Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M.
登録日2018-07-10
公開日2018-09-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8JNK
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BU of 8jnk by Molmil
Crystal structure of human ALKBH3 bound to ssDNA through active site crosslink
分子名称: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, DNA, MANGANESE (II) ION, ...
著者Zhang, L.
登録日2023-06-06
公開日2024-01-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献The Molecular Basis of Human ALKBH3 Mediated RNA N 1 -methyladenosine (m 1 A) Demethylation.
Angew.Chem.Int.Ed.Engl., 63, 2024
8JNR
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BU of 8jnr by Molmil
Crystal structure of human ALKBH3 bound to 3mC containing ssDNA through distal crosslink
分子名称: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, DNA, MANGANESE (II) ION, ...
著者Zhang, L.
登録日2023-06-06
公開日2024-01-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.66 Å)
主引用文献The Molecular Basis of Human ALKBH3 Mediated RNA N 1 -methyladenosine (m 1 A) Demethylation.
Angew.Chem.Int.Ed.Engl., 63, 2024
2TGD
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BU of 2tgd by Molmil
LACK OF THE TRANSITION STATE STABILIZATION SITE IS A FACTOR IN THE INACTIVITY OF TRYPSINOGEN, A SERINE PROTEASE ZYMOGEN. STRUCTURE OF DFP INHIBITED BOVINE TRYPSINOGEN AT 2.1 ANGSTROMS RESOLUTION
分子名称: CALCIUM ION, DIISOPROPYL PHOSPHONATE, TRYPSINOGEN
著者Jones, M.O, Stroud, R.M.
登録日1986-03-17
公開日1986-05-07
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Lack of the Transition State Stabilization Site is a Factor in the Inactivity of Trypsinogen, a Serine Protease Zymogen. Structure of Dfp Inhibited Bovine Trypsinogen at 2.1 Angstroms Resolution
To be Published
4I18
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BU of 4i18 by Molmil
Crystal structure of human prolactin receptor complexed with Fab fragment
分子名称: ACETATE ION, CALCIUM ION, GLYCEROL, ...
著者Duguid, E.M, Mukherjee, S, Kouadio, J.L.
登録日2012-11-20
公開日2013-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.238 Å)
主引用文献Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling.
Cell Commun Signal, 13, 2015
5VKD
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BU of 5vkd by Molmil
Crystal structure of C-terminal domain of Ebola (Bundibugyo) nucleoprotein in complex with Fab fragment
分子名称: Fab Heavy Chain, Fab light chain, Nucleoprotein
著者Radwanska, M.J, Derewenda, U, Kossiakoff, A, Derewenda, Z.S.
登録日2017-04-21
公開日2018-04-25
最終更新日2022-11-16
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab.
Acta Crystallogr D Struct Biol, 74, 2018
1FAN
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BU of 1fan by Molmil
CREVICE-FORMING MUTANTS IN THE RIGID CORE OF BOVINE PANCREATIC TRYPSIN INHIBITOR: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A
分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR
著者Danishefsky, A.T, Wlodawer, A, Kim, K.-S, Tao, F, Woodward, C.
登録日1992-08-21
公開日1993-10-31
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A.
Protein Sci., 2, 1993
7T9X
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BU of 7t9x by Molmil
Saccharomyces cerevisiae Pex12 RING domain
分子名称: Peroxisome assembly protein 12, ZINC ION
著者Feng, P, Rapoport, T.
登録日2021-12-20
公開日2022-06-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel.
Nature, 607, 2022
7T92
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BU of 7t92 by Molmil
Structure of the peroxisomal retro-translocon formed by a heterotrimeric ubiquitin ligase complex
分子名称: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, Fab heavy chain, ...
著者Peiqiang, F, Tom, R.
登録日2021-12-17
公開日2022-07-06
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel.
Nature, 607, 2022
8T7F
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BU of 8t7f by Molmil
Structure of the S1 variant of Fab F1
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, S1 variant of Fab F1 heavy chain, S1 variant of Fab F1 light chain, ...
著者Singer, A.U, Bruce, H.A, Enderle, L, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S.
登録日2023-06-20
公開日2023-11-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8T7G
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BU of 8t7g by Molmil
Structure of the CK variant of Fab F1 (FabC-F1)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CK variant of Fab F1 heavy chain, ...
著者Singer, A.U, Bruce, H.A, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S.
登録日2023-06-20
公開日2023-11-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
8T7I
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BU of 8t7i by Molmil
Structure of the S1CE variant of Fab F1 (FabS1CE-F1)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, S1CE variant of Fab F1 heavy chain, ...
著者Singer, A.U, Bruce, H.A, Enderle, L, Blazer, L, Adams, J.J, Sicheri, F, Sidhu, S.S.
登録日2023-06-20
公開日2023-11-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Engineered antigen-binding fragments for enhanced crystallization of antibody:antigen complexes.
Protein Sci., 33, 2024
9PTI
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BU of 9pti by Molmil
BASIC PANCREATIC TRYPSIN INHIBITOR (MET 52 OXIDIZED)
分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, PHOSPHATE ION
著者Eigenbrot, C, Randal, M, Kossiakoff, A.A.
登録日1991-04-08
公開日1992-04-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献

1NAG
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BU of 1nag by Molmil
CREVICE-FORMING MUTANTS IN THE RIGID CORE OF BOVINE PANCREATIC TRYPSIN INHIBITOR: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A
分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, PHOSPHATE ION
著者Danishefsky, A.T, Wlodawer, A, Kim, K.-S, Tao, F, Woodward, C.
登録日1992-08-18
公開日1993-10-31
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A.
Protein Sci., 2, 1993
6VI1
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BU of 6vi1 by Molmil
Structure of Fab4 bound to P22 TerL(1-33)
分子名称: Synthetic Fab4 heavy chain, Synthetic Fab4 light chain, Terminase, ...
著者Cingolani, G, Lokareddy, R, Ko, Y.
登録日2020-01-11
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
6VI2
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BU of 6vi2 by Molmil
Structure of the unaligned Fab4
分子名称: FAB4 heavy chain, FAB4 light chain
著者Cingolani, G, Lokareddy, R, Ko, Y.
登録日2020-01-11
公開日2020-09-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
6WW2
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BU of 6ww2 by Molmil
Structure of human Frizzled5 by fiducial-assisted cryo-EM
分子名称: Frizzled-5,Soluble cytochrome b562, anti-BRIL Fab Heavy chain, anti-BRIL Fab Light chain, ...
著者Tsutsumi, N, Jude, K.M, Gati, C, Garcia, K.C.
登録日2020-05-07
公開日2020-08-19
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling.
Elife, 9, 2020
4JO7
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BU of 4jo7 by Molmil
Crystal structure of the human Nup49CCS2+3* Nup57CCS3* complex with 2:2 stoichiometry
分子名称: Nucleoporin p54, Nucleoporin p58/p45
著者Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A.
登録日2013-03-17
公開日2014-09-17
最終更新日2016-02-03
実験手法X-RAY DIFFRACTION (1.752 Å)
主引用文献Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
4JNU
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BU of 4jnu by Molmil
Crystal structure of the human Nup57CCS3* coiled-coil segment, space group P21
分子名称: Nucleoporin p54
著者Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A.
登録日2013-03-15
公開日2014-09-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.445 Å)
主引用文献Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
7KEO
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BU of 7keo by Molmil
Crystal structure of K29-linked di-ubiquitin in complex with synthetic antigen binding fragment
分子名称: PHOSPHATE ION, Synthetic antigen binding fragment, heavy chain, ...
著者Yu, Y, Zheng, Q, Erramilli, S, Pan, M, Kossiakoff, A, Liu, L, Zhao, M.
登録日2020-10-11
公開日2021-07-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle.
Nat.Chem.Biol., 17, 2021

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