5JV4
 
 | | Structure of F420 binding protein, MSMEG_6526, from Mycobacterium smegmatis with F420 bound | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, COENZYME F420, ... | | 著者 | Lee, B.M, Carr, P.D, Jackson, C.J. | | 登録日 | 2016-05-10 | | 公開日 | 2017-08-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of F420 binding protein, MSMEG_6526, from Mycobacterium smegmatis with F420 bound
To Be Published
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4PBF
 | | Phosphotriesterase variant Rev12 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-revR12, ... | | 著者 | Campbell, E, Kaltenbach, M, Tokuriki, N, Jackson, C.J. | | 登録日 | 2014-04-12 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat. Chem. Biol., 12, 2016
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4PBE
 | | Phosphotriesterase Variant Rev6 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase variant PTE-revR6, ... | | 著者 | Campbell, E, Kaltenbach, M, Tokuriki, N, Jackson, C.J. | | 登録日 | 2014-04-12 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat. Chem. Biol., 12, 2016
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4PCP
 | | Crystal structure of Phosphotriesterase variant R0 | | 分子名称: | CACODYLATE ION, Phosphotriesterase variant PTE-R0, ZINC ION | | 著者 | Campbell, E, Kaltenbach, M, Tokuriki, N, Jackson, C.J. | | 登録日 | 2014-04-16 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function.
Nat. Chem. Biol., 12, 2016
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7RG8
 | | Crystal Structure of a Stable Heparanase Mutant | | 分子名称: | ACETATE ION, Heparanase 50 kDa subunit, Heparanase 8 kDa subunit, ... | | 著者 | Whitefield, C, Hong, N.S, Jackson, C.J. | | 登録日 | 2021-07-14 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Computational design and experimental characterisation of a stable human heparanase variant.
Rsc Chem Biol, 3, 2022
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4ZKY
 | | Structure of F420 binding protein, MSMEG_6526, from Mycobacterium smegmatis | | 分子名称: | CHLORIDE ION, IODIDE ION, Pyridoxamine 5-phosphate oxidase, ... | | 著者 | Lee, B.M, Carr, P.D, Ahmed, F.H, Jackson, C.J. | | 登録日 | 2015-05-01 | | 公開日 | 2015-10-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Sequence-Structure-Function Classification of a Catalytically Diverse Oxidoreductase Superfamily in Mycobacteria.
J.Mol.Biol., 427, 2015
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5C8V
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5CH3
 | | E3 alpha-esterase-7 carboxylesterase | | 分子名称: | Carboxylic ester hydrolase | | 著者 | Correy, G, Mabbitt, P, Jackson, C.J. | | 登録日 | 2015-07-10 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography.
Structure, 24, 2016
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5CH5
 | | E3 alpha-esterase-7 carboxylesterase | | 分子名称: | Carboxylic ester hydrolase, DIETHYL HYDROGEN PHOSPHATE | | 著者 | Correy, G, Mabbitt, P, Jackson, C.J. | | 登録日 | 2015-07-10 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography.
Structure, 24, 2016
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5BNC
 | | Structure of heme binding protein MSMEG_6519 from Mycobacterium smegmatis | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, NICKEL (II) ION, ... | | 著者 | Ahmed, F.H, Carr, P.D, Jackson, C.J. | | 登録日 | 2015-05-26 | | 公開日 | 2015-10-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Sequence-Structure-Function Classification of a Catalytically Diverse Oxidoreductase Superfamily in Mycobacteria.
J.Mol.Biol., 427, 2015
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4ZV1
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4ZV2
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6AML
 | | Phosphotriesterase variant S8 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... | | 著者 | Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. | | 登録日 | 2017-08-09 | | 公開日 | 2018-08-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Phosphotriesterase variant S8
To Be Published
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6B2F
 | | Phosphotriesterase variant S5 + TS analogue | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Phosphotriesterase, ZINC ION, ... | | 著者 | Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. | | 登録日 | 2017-09-20 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.775 Å) | | 主引用文献 | Phosphotriesterase variant S5 + TS analogue
To Be Published
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6BH7
 | | Phosphotriesterase variant R18+254S | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... | | 著者 | Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. | | 登録日 | 2017-10-30 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Phosphotriesterase variant R18+254S
To Be Published
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6BHK
 | | Phosphotriesterase variant R18deltaL7 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Phosphotriesterase, ZINC ION | | 著者 | Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. | | 登録日 | 2017-10-30 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Phosphotriesterase variant R18deltaL7
To Be Published
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6BQE
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6BHL
 | | Phosphotriesterase variant S5deltaL7 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... | | 著者 | Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. | | 登録日 | 2017-10-30 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Phosphotriesterase variant S5deltaL7
To Be Published
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6BM9
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4E3T
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7KW3
 | | Non Ribosomal PCP domain | | 分子名称: | PCP domain, SULFATE ION | | 著者 | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | | 登録日 | 2020-11-29 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity.
Nat Commun, 12, 2021
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7KL8
 | | Structure of F420 binding protein Rv1558 from Mycobacterium tuberculosis with F420 bound | | 分子名称: | COENZYME F420, COENZYME F420-3, Deazaflavin-dependent nitroreductase, ... | | 著者 | Lee, B.M, Tan, L.L, Jackson, C.J. | | 登録日 | 2020-10-29 | | 公開日 | 2021-03-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.469 Å) | | 主引用文献 | Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F 420 H 2 -dependent reduction.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7KW0
 | | Non-ribosomal didomain (stabilised glycine-PCP-C) acceptor bound state | | 分子名称: | N-{2-[(2-aminoethyl)sulfanyl]ethyl}-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, PCP-C didomain | | 著者 | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | | 登録日 | 2020-11-29 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity.
Nat Commun, 12, 2021
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7KVW
 | | Non-ribosomal didomain (holo-PCP-C) acceptor bound state | | 分子名称: | 4'-PHOSPHOPANTETHEINE, PCP-C didomain | | 著者 | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | | 登録日 | 2020-11-29 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity.
Nat Commun, 12, 2021
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7KW2
 | | Non-ribosomal didomain (holo-PCP-C) acceptor bound state, R2577G | | 分子名称: | 4'-PHOSPHOPANTETHEINE, PCP-C didomain | | 著者 | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | | 登録日 | 2020-11-29 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity.
Nat Commun, 12, 2021
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