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COMPARISON OF THE CRYSTAL STRUCTURE OF BACTERIOPHAGE T4 LYSOZYME AT LOW, MEDIUM, AND HIGH IONIC STRENGTHS
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者	Bell, J.A, Wilson, K, Zhang, X.-J, Faber, H.R, Nicholson, H, Matthews, B.W.
登録日	1991-01-25
公開日	1992-07-15
最終更新日	2025-03-26
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Comparison of the crystal structure of bacteriophage T4 lysozyme at low, medium, and high ionic strengths. Proteins, 10, 1991

4A1X

Co-Complex structure of NS3-4A protease with the inhibitory peptide CP5-46-A (Synchrotron data)
分子名称:	CHLORIDE ION, CP5-46-A PEPTIDE, NONSTRUCTURAL PROTEIN 4A, ...
著者	Schmelz, S, Kuegler, J, Collins, J, Heinz, D.
登録日	2011-09-20
公開日	2012-09-19
最終更新日	2024-10-16
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	High Affinity Peptide Inhibitors of the Hepatitis C Virus Ns3-4A Protease Refractory to Common Resistant Mutants. J.Biol.Chem., 287, 2012

119L

THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者	Blaber, M, Matthews, B.W.
登録日	1993-05-28
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme. Biochemistry, 32, 1993

118L

THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者	Blaber, M, Matthews, B.W.
登録日	1993-05-28
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme. Biochemistry, 32, 1993

120L

THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者	Blaber, M, Matthews, B.W.
登録日	1993-05-28
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme. Biochemistry, 32, 1993

122L

THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者	Blaber, M, Matthews, B.W.
登録日	1993-05-28
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme. Biochemistry, 32, 1993

123L

THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者	Blaber, M, Matthews, B.W.
登録日	1993-05-28
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme. Biochemistry, 32, 1993

125L

THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者	Blaber, M, Matthews, B.W.
登録日	1993-05-28
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme. Biochemistry, 32, 1993

126L

THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者	Blaber, M, Matthews, B.W.
登録日	1993-05-28
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme. Biochemistry, 32, 1993

128L

THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者	Blaber, M, Matthews, B.W.
登録日	1993-05-28
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme. Biochemistry, 32, 1993

127L

THE ENERGETIC COST AND THE STRUCTURAL CONSEQUENCES OF BURYING A HYDROXYL GROUP WITHIN THE CORE OF A PROTEIN DETERMINED FROM ALA TO SER AND VAL TO THR SUBSTITUTIONS IN T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者	Blaber, M, Matthews, B.W.
登録日	1993-05-28
公開日	1993-10-31
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme. Biochemistry, 32, 1993

1L44

CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability. J.Mol.Biol., 221, 1991

1L58

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, T4 LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2025-03-26
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	To be Published

1L71

MULTIPLE STABILIZING ALANINE REPLACEMENTS WITHIN ALPHA-HELIX 126-134 OF T4 LYSOZYME HAVE INDEPENDENT, ADDITIVE EFFECTS ON BOTH STRUCTURE AND STABILITY
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Zhang, X, Matthews, B.W.
登録日	1991-09-23
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Multiple alanine replacements within alpha-helix 126-134 of T4 lysozyme have independent, additive effects on both structure and stability. Protein Sci., 1, 1992

1L76

TOLERANCE OF T4 LYSOZYME TO PROLINE SUBSTITUTIONS WITHIN THE LONG INTERDOMAIN ALPHA-HELIX ILLUSTRATES THE ADAPTABILITY OF PROTEINS TO POTENTIALLY DESTABILIZING LESIONS
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Sauer, U, Matthews, B.W.
登録日	1991-09-23
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Tolerance of T4 lysozyme to proline substitutions within the long interdomain alpha-helix illustrates the adaptability of proteins to potentially destabilizing lesions. J.Biol.Chem., 267, 1992

1L63

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.75 Å)
主引用文献	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

1L89

SIMILAR HYDROPHOBIC REPLACEMENTS OF LEU 99 AND PHE 153 WITHIN THE CORE OF T4 LYSOZYME HAVE DIFFERENT STRUCTURAL AND THERMODYNAMIC CONSEQUENCES
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, T4 LYSOZYME
著者	Eriksson, A.E, Matthews, B.W.
登録日	1992-01-21
公開日	1993-10-31
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Similar hydrophobic replacements of Leu99 and Phe153 within the core of T4 lysozyme have different structural and thermodynamic consequences. J.Mol.Biol., 229, 1993

1L36

TOWARD A SIMPLIFICATION OF THE PROTEIN FOLDING PROBLEM: A STABILIZING POLYALANINE ALPHA-HELIX ENGINEERED IN T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Zhang, X.-J, Baase, W.A, Matthews, B.W.
登録日	1990-12-26
公開日	1991-10-15
最終更新日	2022-11-23
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Toward a simplification of the protein folding problem: a stabilizing polyalanine alpha-helix engineered in T4 lysozyme. Biochemistry, 30, 1991

1L52

STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE PACKING OF TWO ALPHA-HELICES IN BACTERIOPHAGE T4 LYSOZYME
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Structural and thermodynamic analysis of the packing of two alpha-helices in bacteriophage T4 lysozyme. J.Mol.Biol., 221, 1991

1L40

CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis. Biochemistry, 30, 1991

1L47

CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability. J.Mol.Biol., 221, 1991

1L50

STRUCTURAL AND THERMODYNAMIC ANALYSIS OF THE PACKING OF TWO ALPHA-HELICES IN BACTERIOPHAGE T4 LYSOZYME
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Structural and thermodynamic analysis of the packing of two alpha-helices in bacteriophage T4 lysozyme. J.Mol.Biol., 221, 1991

1L38

CONTRIBUTIONS OF ENGINEERED SURFACE SALT BRIDGES TO THE STABILITY OF T4 LYSOZYME DETERMINED BY DIRECTED MUTAGENESIS
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Contributions of engineered surface salt bridges to the stability of T4 lysozyme determined by directed mutagenesis. Biochemistry, 30, 1991

1L45

CUMULATIVE SITE-DIRECTED CHARGE-CHANGE REPLACEMENTS IN BACTERIOPHAGE T4 LYSOZYME SUGGEST THAT LONG-RANGE ELECTROSTATIC INTERACTIONS CONTRIBUTE LITTLE TO PROTEIN STABILITY
分子名称:	T4 LYSOZYME
著者	Daopin, S, Matthews, B.W.
登録日	1991-01-28
公開日	1991-10-15
最終更新日	2024-05-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Cumulative site-directed charge-change replacements in bacteriophage T4 lysozyme suggest that long-range electrostatic interactions contribute little to protein stability. J.Mol.Biol., 221, 1991

1L55

ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME
分子名称:	BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME
著者	Nicholson, H, Matthews, B.W.
登録日	1991-05-06
公開日	1991-10-15
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991

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