7DDW
| Crystal structure of a mutant Staphylococcus equorum manganese superoxide dismutase S126C | 分子名称: | MANGANESE (II) ION, Superoxide dismutase | 著者 | Retnoningrum, D.S, Yoshida, H, Razani, M.D, Meidianto, V.F, Hartanto, A, Artarini, A, Ismaya, W.T. | 登録日 | 2020-10-30 | 公開日 | 2021-04-07 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | The role of S126 in the Staphylococcus equorum MnSOD activity and stability. J.Struct.Biol., 213, 2021
|
|
5JXQ
| TRNA-GUANINE TRANSGLYCOSYLASE (TGT) IN COMPLEX WITH 6-AMINO-2-{[4-(2-HYDROXYETHYL)PHENETHYL]AMINO}-1,7-DIHYDRO-8H-IMIDAZO[4,5-g]QUINAZOLIN-8-ONE | 分子名称: | 6-amino-2-({2-[4-(2-hydroxyethyl)phenyl]ethyl}amino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one, CHLORIDE ION, GLYCEROL, ... | 著者 | Neeb, M, Heine, A, Klebe, G. | 登録日 | 2016-05-13 | 公開日 | 2016-08-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Occupying a flat subpocket in a tRNA-modifying enzyme with ordered or disordered side chains: Favorable or unfavorable for binding? Bioorg.Med.Chem., 24, 2016
|
|
3SQC
| SQUALENE-HOPENE CYCLASE | 分子名称: | SQUALENE--HOPENE CYCLASE | 著者 | Wendt, K.U, Schulz, G.E. | 登録日 | 1998-09-04 | 公開日 | 1999-05-18 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The structure of the membrane protein squalene-hopene cyclase at 2.0 A resolution. J.Mol.Biol., 286, 1999
|
|
3O70
| PHD-type zinc finger of human PHD finger protein 13 | 分子名称: | GLYCEROL, PHD finger protein 13, ZINC ION | 著者 | Lam, R, Bian, C.B, Xu, C, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2010-07-29 | 公開日 | 2010-09-29 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3. Elife, 5, 2016
|
|
3O7A
| Crystal structure of PHF13 in complex with H3K4me3 | 分子名称: | GLYCEROL, H3K4ME3 HISTONE 11MER-PEPTIDE, PHD finger protein 13 variant, ... | 著者 | Bian, C.B, Lam, R, Xu, C, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2010-07-30 | 公開日 | 2010-10-06 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3. Elife, 5, 2016
|
|
6EQM
| Crystal Structure of Human BACE-1 in Complex with CNP520 | 分子名称: | Beta-secretase 1, ~{N}-[6-[(3~{R},6~{R})-5-azanyl-3,6-dimethyl-6-(trifluoromethyl)-2~{H}-1,4-oxazin-3-yl]-5-fluoranyl-pyridin-2-yl]-3-chloranyl-5-(trifluoromethyl)pyridine-2-carboxamide | 著者 | Rondeau, J.-M, Wirth, E. | 登録日 | 2017-10-13 | 公開日 | 2018-09-19 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer's disease. EMBO Mol Med, 10, 2018
|
|
2SQC
| |
6FH1
| Protein arginine kinase McsB in the apo state | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, IMIDAZOLE, ... | 著者 | Suskiewicz, M.J, Heuck, A, Vu, L.D, Clausen, T. | 登録日 | 2018-01-12 | 公開日 | 2019-02-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of McsB, a protein kinase for regulated arginine phosphorylation. Nat.Chem.Biol., 15, 2019
|
|
8ATX
| |
8AUW
| |
8ATU
| |
8AUK
| Cryo-EM structure of human BIRC6 in complex with HTRA2. | 分子名称: | Baculoviral IAP repeat-containing protein 6, Serine protease HTRA2, mitochondrial, ... | 著者 | Ehrmann, J.F, Grabarczyk, D.B, Clausen, T. | 登録日 | 2022-08-25 | 公開日 | 2023-02-15 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex. Science, 379, 2023
|
|
5LWC
| NMR solution structure of bacteriocin BacSp222 from Staphylococcus pseudintermedius 222 | 分子名称: | Bacteriocin BacSp222 | 著者 | Nowakowski, M.E, Ejchart, A.O, Jaremko, L, Wladyka, B, Mak, P. | 登録日 | 2016-09-15 | 公開日 | 2017-10-25 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Spatial attributes of the four-helix bundle group of bacteriocins - The high-resolution structure of BacSp222 in solution. Int.J.Biol.Macromol., 107, 2018
|
|
2V1V
| |
2M3W
| |
6RKQ
| Crystal Structure of TGT in complex with N2-methyl-8-(prop-1-yn-1-yl)-3H,7H,8H-imidazo[4,5-g]quinazoline-2,6-diamine | 分子名称: | (8~{R})-~{N}2-methyl-8-prop-1-ynyl-7,8-dihydro-3~{H}-imidazo[4,5-g]quinazoline-2,6-diamine, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Hassaan, E, Heine, A, Klebe, G. | 登録日 | 2019-04-30 | 公開日 | 2020-06-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.665 Å) | 主引用文献 | Fragment Screening Hit Draws Attention to a Novel Transient Pocket Adjacent to the Recognition Site of the tRNA-Modifying Enzyme TGT. J.Med.Chem., 63, 2020
|
|
6RKT
| Crystal Structure of TGT in complex with N2-methyl-1H,7H,8H-imidazo[4,5-g]quinazoline-2,6-diamine | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, Queuine tRNA-ribosyltransferase, ... | 著者 | Hassaan, E, Heine, A, Klebe, G. | 登録日 | 2019-04-30 | 公開日 | 2020-06-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.746 Å) | 主引用文献 | Fragment Screening Hit Draws Attention to a Novel Transient Pocket Adjacent to the Recognition Site of the tRNA-Modifying Enzyme TGT. J.Med.Chem., 63, 2020
|
|
3MGX
| |
1HPH
| |
1QHL
| |
1TIV
| |
1OFC
| nucleosome recognition module of ISWI ATPase | 分子名称: | 4-deoxy-alpha-D-glucopyranose, GLYCEROL, ISWI PROTEIN, ... | 著者 | Grune, T, Muller, C.W. | 登録日 | 2003-04-10 | 公開日 | 2003-09-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure and Functional Analysis of a Nucleosome Recognition Module of the Remodeling Factor Iswi Mol.Cell, 12, 2003
|
|
2RQS
| 3D structure of Pin from the psychrophilic archeon Cenarcheaum symbiosum (CsPin) | 分子名称: | Parvulin-like peptidyl-prolyl isomerase | 著者 | Zhukov, I, Jaremko, L, Jaremko, M, Mueller, J.W, Bayer, P. | 登録日 | 2009-11-17 | 公開日 | 2010-11-24 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and Dynamics of the First Archaeal Parvulin Reveal a New Functionally Important Loop in Parvulin-type Prolyl Isomerases J.Biol.Chem., 286, 2011
|
|
1SQC
| |
1TBC
| |