3PC2
 
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3PC4
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3PC3
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3QMW
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3QMV
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3SBY
 | | Crystal Structure of SeMet-Substituted Apo-MMACHC (1-244), a human B12 processing enzyme | | 分子名称: | Methylmalonic aciduria and homocystinuria type C protein | | 著者 | Koutmos, M, Gherasim, C, Smith, J.L, Banerjee, R. | | 登録日 | 2011-06-06 | | 公開日 | 2011-06-22 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Structural basis of multifunctionality in a vitamin B12-processing enzyme.
J.Biol.Chem., 286, 2011
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3SC0
 | | Crystal Structure of MMACHC (1-238), a human B12 processing enzyme, complexed with MethylCobalamin | | 分子名称: | CO-METHYLCOBALAMIN, Methylmalonic aciduria and homocystinuria type C protein | | 著者 | Koutmos, M, Gherasim, C, Smith, J.L, Banerjee, R. | | 登録日 | 2011-06-06 | | 公開日 | 2011-06-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural basis of multifunctionality in a vitamin B12-processing enzyme.
J.Biol.Chem., 286, 2011
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3SBZ
 | | Crystal Structure of Apo-MMACHC (1-244), a human B12 processing enzyme | | 分子名称: | GLYCEROL, MALONATE ION, Methylmalonic aciduria and homocystinuria type C protein | | 著者 | Koutmos, M, Gherasim, C, Smith, J.L, Banerjee, R. | | 登録日 | 2011-06-06 | | 公開日 | 2011-06-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis of multifunctionality in a vitamin B12-processing enzyme.
J.Biol.Chem., 286, 2011
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6NET
 | | FAD-dependent monooxygenase TropB from T. stipitatus substrate complex | | 分子名称: | 2,4-dihydroxy-3,6-dimethylbenzaldehyde, CHLORIDE ION, FAD-dependent monooxygenase tropB, ... | | 著者 | Rodriguez Benitez, A, Tweedy, S.E, Baker Dockrey, S.A, Lukowski, A.L, Wymore, T, Khare, D, Brooks, C.L, Palfey, B.A, Smith, J.L, Narayan, A.R.H. | | 登録日 | 2018-12-18 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization.
Acs Catalysis, 9, 2019
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6NKK
 | | Structure of PhqE Reductase/Diels-Alderase from Penicillium fellutanum in complex with NADP+ and premalbrancheamide | | 分子名称: | (5aS,12aS,13aS)-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short chain dehydrogenase | | 著者 | Newmister, S.A, Dan, Q, Smith, J.L, Sherman, D.H. | | 登録日 | 2019-01-07 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.299 Å) | | 主引用文献 | Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase.
Nat.Chem., 11, 2019
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6NKI
 | | Structure of PhqB Reductase Domain from Penicillium fellutanum | | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NRPS | | 著者 | Dan, Q, Newmister, S.A, Smith, J.L, Sherman, D.H. | | 登録日 | 2019-01-07 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase.
Nat.Chem., 11, 2019
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6NEU
 | | FAD-dependent monooxygenase TropB from T. stipitatus R206Q variant | | 分子名称: | CHLORIDE ION, FAD-dependent monooxygenase tropB, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Rodriguez Benitez, A, Tweedy, S.E, Baker Dockrey, S.A, Lukowski, A.L, Wymore, T, Khare, D, Brooks, C.L, Palfey, B.A, Smith, J.L, Narayan, A.R.H. | | 登録日 | 2018-12-18 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization.
Acs Catalysis, 9, 2019
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6NKM
 | | Structure of PhqE D166N Reductase/Diels-Alderase from Penicillium fellutanum in complex with NADP+ and substrate | | 分子名称: | 3-{[2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]methyl}-8H-pyrrolo[1,2-a]pyrazin-5-ium-1-olate, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short chain dehydrogenase | | 著者 | Newmister, S.A, Dan, Q, Smith, J.L, Sherman, D.H. | | 登録日 | 2019-01-07 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.896 Å) | | 主引用文献 | Fungal indole alkaloid biogenesis through evolution of a bifunctional reductase/Diels-Alderase.
Nat.Chem., 11, 2019
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6NEV
 | | FAD-dependent monooxygenase TropB from T. stipitatus Y239F Variant | | 分子名称: | CHLORIDE ION, FAD-dependent monooxygenase tropB, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Rodriguez Benitez, A, Tweedy, S.E, Baker Dockrey, S.A, Lukowski, A.L, Wymore, T, Khare, D, Palfey, B.A, Smith, J.L, Narayan, A.R.H. | | 登録日 | 2018-12-18 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | | 主引用文献 | Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization.
Acs Catalysis, 9, 2019
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1JVN
 | | CRYSTAL STRUCTURE OF IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE: A TUNNEL THROUGH A (BETA/ALPHA)8 BARREL JOINS TWO ACTIVE SITES | | 分子名称: | BIFUNCTIONAL HISTIDINE BIOSYNTHESIS PROTEIN HISHF, NICKEL (II) ION, PYROPHOSPHATE 2-, ... | | 著者 | Chaudhuri, B.N, Smith, J.L, Davisson, V.J, Myers, R.S, Lange, S.C, Chittur, S.V. | | 登録日 | 2001-08-30 | | 公開日 | 2001-10-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of imidazole glycerol phosphate synthase: a tunnel through a (beta/alpha)8 barrel joins two active sites.
Structure, 9, 2001
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6PVF
 | | Crystal structure of PhqK in complex with malbrancheamide B | | 分子名称: | (5aS,12aS,13aS)-9-chloro-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one, FAD monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Fraley, A.E, Smith, J.L, Sherman, D.H. | | 登録日 | 2019-07-20 | | 公開日 | 2020-01-22 | | 最終更新日 | 2020-02-19 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway.
J.Am.Chem.Soc., 142, 2020
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6PVH
 | | Crystal structure of PhqK in complex with paraherquamide K | | 分子名称: | (7aS,12S,12aR,13aS)-3,3,12,14,14-pentamethyl-3,7,11,12,13,13a,14,15-octahydro-8H,10H-7a,12a-(epiminomethano)indolizino[6,7-h]pyrano[3,2-a]carbazol-16-one, FAD monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Fraley, A.E, Smith, J.L, Sherman, D.H. | | 登録日 | 2019-07-20 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway.
J.Am.Chem.Soc., 142, 2020
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6PVG
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6PVI
 | | Crystal structure of PhqK in complex with paraherquamide L | | 分子名称: | (8aS,13S,13aR,14aS)-4,4,13,15,15-pentamethyl-12,13,14,14a,15,16-hexahydro-4H,8H,9H,11H-8a,13a-(epiminomethano)[1,4]dioxepino[2,3-a]indolizino[6,7-h]carbazol-17-one, FAD monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Fraley, A.E, Smith, J.L, Sherman, D.H. | | 登録日 | 2019-07-20 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.093 Å) | | 主引用文献 | Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway.
J.Am.Chem.Soc., 142, 2020
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6PVJ
 | | Crystal structure of PhqK in complex with malbrancheamide C | | 分子名称: | (5aS,12aS,13aS)-9-bromo-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7,6-b]carbazol-14-one, FAD monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Fraley, A.E, Smith, J.L, Sherman, D.H. | | 登録日 | 2019-07-20 | | 公開日 | 2020-01-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Molecular Basis for Spirocycle Formation in the Paraherquamide Biosynthetic Pathway.
J.Am.Chem.Soc., 142, 2020
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1NON
 | | PyrR, the regulator of the pyrimidine biosynthetic operon in Bacillus caldolyticus | | 分子名称: | PyrR bifunctional protein | | 著者 | Switzer, R.L, Chander, P, Smith, J.L, Halbig, K.M, Miller, J.K, Bonner, H.K, Grabner, G.K. | | 登録日 | 2003-01-16 | | 公開日 | 2004-05-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the Nucleotide Complex of PyrR, the pyr Attenuation Protein from Bacillus caldolyticus, Suggests Dual Regulation by Pyrimidine and Purine Nucleotides
J.Bacteriol., 187, 2005
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3BQ6
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3BOL
 | | Cobalamin-dependent methionine synthase (1-566) from Thermotoga maritima complexed with Zn2+ | | 分子名称: | 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydrofolate S-homocysteine methyltransferase, POTASSIUM ION, ... | | 著者 | Koutmos, M, Smith, J.L, Ludwig, M.L. | | 登録日 | 2007-12-17 | | 公開日 | 2008-03-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Metal active site elasticity linked to activation of homocysteine in methionine synthases.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BQ5
 | | Crystal Structure of T. maritima Cobalamin-Independent Methionine Synthase complexed with Zn2+ and Homocysteine (Monoclinic) | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase, ... | | 著者 | Pejchal, R, Smith, J.L, Ludwig, M.L. | | 登録日 | 2007-12-19 | | 公開日 | 2008-03-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Metal active site elasticity linked to activation of homocysteine in methionine synthases.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BOF
 | | Cobalamin-dependent methionine synthase (1-566) from Thermotoga maritima complexed with Zn2+ and Homocysteine | | 分子名称: | 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydrofolate S-homocysteine methyltransferase, POTASSIUM ION, ... | | 著者 | Koutmos, M, Smith, J.L, Ludwig, M.L. | | 登録日 | 2007-12-17 | | 公開日 | 2008-03-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Metal active site elasticity linked to activation of homocysteine in methionine synthases.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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