5HEC
| CgT structure in dimer | 分子名称: | Putative glycosyltransferase (GalT1) | 著者 | Zhang, H, Wu, H. | 登録日 | 2016-01-05 | 公開日 | 2016-08-31 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.395 Å) | 主引用文献 | New Helical Binding Domain Mediates a Glycosyltransferase Activity of a Bifunctional Protein. J.Biol.Chem., 291, 2016
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5FI7
| Crystal structure of human GAC in complex with inhibitor UPGL_00015: 2-phenyl-~{N}-[5-[(3~{S})-3-[[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]oxy]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]ethanamide | 分子名称: | 2-phenyl-~{N}-[5-[(3~{S})-3-[[5-(2-phenylethanoylamino)-1,3,4-thiadiazol-2-yl]oxy]pyrrolidin-1-yl]-1,3,4-thiadiazol-2-yl]ethanamide, Glutaminase kidney isoform, mitochondrial | 著者 | Huang, Q, Cerione, R. | 登録日 | 2015-12-22 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Design and evaluation of novel glutaminase inhibitors. Bioorg.Med.Chem., 24, 2016
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7FCZ
| Crystal Structure of human RIPK1 kinase domain in complex with a novel inhibitor | 分子名称: | N-[(3S)-7-(2-cyclopropylethynyl)-5-methyl-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4H-1,2,4-triazole-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 1 | 著者 | Su, H.X, Xie, H, Nie, T.Q, Li, M.J, Xu, Y.C. | 登録日 | 2021-07-15 | 公開日 | 2022-01-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis. Angew.Chem.Int.Ed.Engl., 61, 2022
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7FD0
| Crystal Structure of human RIPK1 kinase domain in complex with a novel inhibitor | 分子名称: | N-[(3S)-5-methyl-7-[2-(oxan-4-yl)ethynyl]-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4H-1,2,4-triazole-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 1 | 著者 | Su, H.X, Xie, H, Nie, T.Q, Li, M.J, Xu, Y.C. | 登録日 | 2021-07-15 | 公開日 | 2022-01-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis. Angew.Chem.Int.Ed.Engl., 61, 2022
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5ZVS
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6A62
| Placental protein 13/galectin-13 variant R53HH57RD33G with Lactose | 分子名称: | Galactoside-binding soluble lectin 13, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Su, J. | 登録日 | 2018-06-26 | 公開日 | 2018-12-26 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Resetting the ligand binding site of placental protein 13/galectin-13 recovers its ability to bind lactose Biosci. Rep., 38, 2018
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6A1T
| Charcot-Leyden crystal protein/Galectin-10 variant E33A with lactose | 分子名称: | Galectin-10, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Su, J. | 登録日 | 2018-06-08 | 公開日 | 2018-12-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Identification of key amino acid residues determining ligand binding specificity, homodimerization and cellular distribution of human galectin-10 Glycobiology, 29, 2019
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6A1U
| Charcot-Leyden crystal protein/Galectin-10 variant E33D | 分子名称: | Galectin-10 | 著者 | Su, J. | 登録日 | 2018-06-08 | 公開日 | 2018-12-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Identification of key amino acid residues determining ligand binding specificity, homodimerization and cellular distribution of human galectin-10 Glycobiology, 29, 2019
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6A64
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6A65
| Placental protein 13/galectin-13 variant R53HR55N with Tris | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Galactoside-binding soluble lectin 13 | 著者 | Su, J. | 登録日 | 2018-06-26 | 公開日 | 2018-12-26 | 実験手法 | X-RAY DIFFRACTION (1.771 Å) | 主引用文献 | Resetting the ligand binding site of placental protein 13/galectin-13 recovers its ability to bind lactose Biosci. Rep., 38, 2018
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6A1Y
| Charcot-Leyden crystal protein/Galectin-10 variant Y35A | 分子名称: | Galectin-10 | 著者 | Su, J. | 登録日 | 2018-06-08 | 公開日 | 2018-12-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Identification of key amino acid residues determining ligand binding specificity, homodimerization and cellular distribution of human galectin-10 Glycobiology, 29, 2019
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6A1V
| Charcot-Leyden crystal protein/Galectin-10 variant E33Q | 分子名称: | Galectin-10 | 著者 | Su, J. | 登録日 | 2018-06-08 | 公開日 | 2018-12-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.984 Å) | 主引用文献 | Identification of key amino acid residues determining ligand binding specificity, homodimerization and cellular distribution of human galectin-10 Glycobiology, 29, 2019
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5ZVT
| Structure of RNA polymerase complex and genome within a dsRNA virus provides insights into the mechanisms of transcription and assembly | 分子名称: | C-terminus of outer capsid protein VP5, Core protein VP6, MYRISTIC ACID, ... | 著者 | Liu, H, Fang, Q, Cheng, L. | 登録日 | 2018-05-12 | 公開日 | 2018-07-04 | 最終更新日 | 2018-07-25 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of RNA polymerase complex and genome within a dsRNA virus provides insights into the mechanisms of transcription and assembly. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6A1S
| Charcot-Leyden crystal protein/Galectin-10 variant E33A | 分子名称: | Galectin-10 | 著者 | Su, J. | 登録日 | 2018-06-08 | 公開日 | 2018-12-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Identification of key amino acid residues determining ligand binding specificity, homodimerization and cellular distribution of human galectin-10 Glycobiology, 29, 2019
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6A1X
| Charcot-Leyden crystal protein/Galectin-10 variant W127A | 分子名称: | Galectin-10 | 著者 | Su, J. | 登録日 | 2018-06-08 | 公開日 | 2018-12-26 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Identification of key amino acid residues determining ligand binding specificity, homodimerization and cellular distribution of human galectin-10 Glycobiology, 29, 2019
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6A63
| Placental protein 13/galectin-13 variant R53HH57R with Lactose | 分子名称: | Galactoside-binding soluble lectin 13, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Su, J. | 登録日 | 2018-06-26 | 公開日 | 2018-12-26 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Resetting the ligand binding site of placental protein 13/galectin-13 recovers its ability to bind lactose Biosci. Rep., 38, 2018
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6A66
| Placental protein 13/galectin-13 variant R53H with Tris | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Galactoside-binding soluble lectin 13 | 著者 | Su, J.Y. | 登録日 | 2018-06-26 | 公開日 | 2018-12-26 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Resetting the ligand binding site of placental protein 13/galectin-13 recovers its ability to bind lactose Biosci. Rep., 38, 2018
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6ISO
| Human SIRT3 Recognizing H3K4cr | 分子名称: | (2E)-BUT-2-ENAL, ARG-THR-LYS-GLN-THR-ALA-ARG, GLYCEROL, ... | 著者 | Wang, Y, Hao, Q. | 登録日 | 2018-11-17 | 公開日 | 2019-01-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Identification of 'erasers' for lysine crotonylated histone marks using a chemical proteomics approach. Elife, 3, 2014
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6K32
| RdRp complex | 分子名称: | 2'-O-methyladenosine 5'-(dihydrogen phosphate), 7-METHYLGUANOSINE, DIPHOSPHATE, ... | 著者 | Li, X.W. | 登録日 | 2019-05-16 | 公開日 | 2019-11-20 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of RdRps Within a Transcribing dsRNA Virus Provides Insights Into the Mechanisms of RNA Synthesis. J.Mol.Biol., 432, 2020
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6K2Z
| Human Galectin-14 with lactose | 分子名称: | Placental protein 13-like, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Su, J. | 登録日 | 2019-05-15 | 公開日 | 2020-06-17 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-function studies of galectin-14, an important effector molecule in embryology. Febs J., 288, 2021
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6K2Y
| Human Galectin-14 | 分子名称: | Placental protein 13-like | 著者 | Su, J. | 登録日 | 2019-05-15 | 公開日 | 2020-06-17 | 最終更新日 | 2021-03-10 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Structure-function studies of galectin-14, an important effector molecule in embryology. Febs J., 288, 2021
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5YL2
| Crystal structure of T2R-TTL-Y28 complex | 分子名称: | (E)-1-(5-methoxy-2,2-dimethyl-chromen-8-yl)-3-(4-methoxy-3-oxidanyl-phenyl)prop-2-en-1-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Yang, J.H, Yang, T, Wen, J.L, Chen, L.J. | 登録日 | 2017-10-16 | 公開日 | 2018-04-18 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in beta-tubulin. J. Biol. Chem., 2018
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2P0E
| Human nicotinamide riboside kinase 1 in complex with tiazofurin | 分子名称: | (1R)-1-[4-(AMINOCARBONYL)-1,3-THIAZOL-2-YL]-1,4-ANHYDRO-D-RIBITOL, CHLORIDE ION, Nicotinamide riboside kinase 1, ... | 著者 | Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Brenner, C, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2007-02-28 | 公開日 | 2007-05-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+). Plos Biol., 5, 2007
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2QSY
| Human nicotinamide riboside kinase 1 in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nicotinamide riboside kinase 1, ... | 著者 | Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Brenner, C, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2007-07-31 | 公開日 | 2007-08-14 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+). Plos Biol., 5, 2007
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2QT1
| Human nicotinamide riboside kinase 1 in complex with nicotinamide riboside | 分子名称: | Nicotinamide riboside, Nicotinamide riboside kinase 1, PHOSPHATE ION, ... | 著者 | Rabeh, W.M, Tempel, W, Nedyalkova, L, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Brenner, C, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2007-07-31 | 公開日 | 2007-08-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Nicotinamide Riboside Kinase Structures Reveal New Pathways to NAD(+). Plos Biol., 5, 2007
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