Search by PDB author

CHK1 kinase domain in complex with diarylpyrazine compound 1
分子名称:	4-[6-(3-hydroxyphenyl)pyrazin-2-yl]benzoic acid, Serine/threonine-protein kinase Chk1
著者	Appleton, B, Wu, P.
登録日	2014-07-24
公開日	2014-12-17
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.05 Å)
主引用文献	Discovery of the 1,7-diazacarbazole class of inhibitors of checkpoint kinase 1. Bioorg.Med.Chem.Lett., 24, 2014

Rational Design of PI3K-alpha Inhibitors that Exhibit Selectivity Over the PI3K-beta Isoform
分子名称:	N~2~-{2-chloro-4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-N~2~,N~8~-dimethyl-4,5-dihydrothieno[3,2-d][1]benzoxepine-2,8-dicarboxamide, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
著者	Murray, J.M, Wiesmann, C.
登録日	2011-08-01
公開日	2011-11-16
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Rational Design of PI3K-alpha Inhibitors that Exhibit Selectivity Over the PI3K-beta Isoform To be Published