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1C4E
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GURMARIN FROM GYMNEMA SYLVESTRE
分子名称: PROTEIN (GURMARIN)
著者Fletcher, J.I, Dingley, A.J, King, G.F.
登録日1999-07-27
公開日1999-08-27
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献High-resolution solution structure of gurmarin, a sweet-taste-suppressing plant polypeptide.
Eur.J.Biochem., 264, 1999
2RVM
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Solution structure of the chromodomain of HP1alpha with the phosphorylated N-terminal tail
分子名称: Chromobox protein homolog 5
著者Kawaguchi, A, Nishimura, Y.
登録日2015-12-18
公開日2016-03-16
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail
Sci Rep, 6, 2016
2RVN
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Solution structure of the chromodomain of HP1a with the phosphorylated N-terminal tail complexed with H3K9me3 peptide
分子名称: 18-mer peptide of Histone H3, Chromobox protein homolog 5
著者Kawaguchi, A, Nishimura, Y.
登録日2015-12-18
公開日2016-03-16
実験手法SOLUTION NMR
主引用文献Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail
Sci Rep, 6, 2016
2RVL
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Solution structure of the chromodomain of HP1alpha with the N-terminal tail
分子名称: Chromobox protein homolog 5
著者Kawaguchi, A, Nishimura, Y.
登録日2015-12-18
公開日2016-03-16
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Extended string-like binding of the phosphorylated HP1 alpha N-terminal tail to the lysine 9-methylated histone H3 tail
Sci Rep, 6, 2016
8CI8
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Cryo-EM structure of the Nup98(298-327) fibril
分子名称: Nuclear pore complex protein Nup98
著者Ibanez de Opakua, A, Cima-Omori, S, Dienemann, C, Zweckstetter, M.
登録日2023-02-09
公開日2024-02-21
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.67 Å)
主引用文献Impact of distinct FG nucleoporin repeats on Nup98 self-association.
Nat Commun, 15, 2024
1RDV
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RUBREDOXIN FROM DESULFOVIBRIO VULGARIS MIYAZAKI F, TRIGONAL CRYSTAL FORM
分子名称: FE (III) ION, RUBREDOXIN
著者Higuchi, Y, Yasuoka, N.
登録日1998-09-30
公開日1999-05-18
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure determination of rubredoxin from Desulfovibrio vulgaris Miyazaki F in two crystal forms.
Acta Crystallogr.,Sect.D, 55, 1999
8OTF
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Ab typeII filament from Guam ALS/PDC
分子名称: Amyloid-beta precursor protein
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OT9
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CTE typeIII tau filament from Guam ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTD
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TMEM106B Fold1-s filament from Guam ALS/PDC
分子名称: Transmembrane protein 106B
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTG
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CTE typeI tau filament from Kii ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTH
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TypeII tau filament from Kii ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTC
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CTE typeII tau filament from Guam ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OT6
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CTE typeI tau filament from Guam ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTE
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TMEM106B Fold I-d filament from Guam ALS/PDC
分子名称: Transmembrane protein 106B
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTJ
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PHF tau filament from Kii ALS/PDC
分子名称: Microtubule-associated protein tau
著者Qi, C, Yang, S, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8OTI
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CTE typeIII tau filament
分子名称: Microtubule-associated protein tau
著者Tetter, S, Qi, C, Ryskeldi-Falcon, B, Scheres, S.H.W, Goedert, M.
登録日2023-04-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Tau filaments from amyotrophic lateral sclerosis/parkinsonism-dementia complex adopt the CTE fold.
Proc.Natl.Acad.Sci.USA, 120, 2023
3IIT
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Factor XA in complex with a cis-1,2-diaminocyclohexane derivative
分子名称: 7-chloro-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{[(5-methyl-5,6-dihydro-4H-pyrrolo[3,4-d][1,3]thiazol-2-yl)carbonyl]amino}cyclohexyl]isoquinoline-3-carboxamide, Activated factor Xa heavy chain, CALCIUM ION, ...
著者Suzuki, M.
登録日2009-08-03
公開日2010-08-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: exploration of 6-6 fused rings as alternative S1 moieties.
Bioorg.Med.Chem., 17, 2009
1IY8
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Crystal Structure of Levodione Reductase
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, LEVODIONE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Sogabe, S, Fukami, T, Shiratori, Y, Yoshizumi, A, Wada, M.
登録日2002-07-25
公開日2003-05-27
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The Crystal Structure and Stereospecificity of Levodione Reductase from Corynebacterium aquaticum M-13
J.BIOL.CHEM., 278, 2003
4NYF
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HIV integrase in complex with inhibitor
分子名称: (2S)-tert-butoxy[4-(4-chlorophenyl)-2-methylquinolin-3-yl]ethanoic acid, CADMIUM ION, Integrase
著者Coulombe, R, Fader, L.
登録日2013-12-10
公開日2014-06-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV-1.
ACS Med Chem Lett, 5, 2014
1ERZ
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CRYSTAL STRUCTURE OF N-CARBAMYL-D-AMINO ACID AMIDOHYDROLASE WITH A NOVEL CATALYTIC FRAMEWORK COMMON TO AMIDOHYDROLASES
分子名称: N-CARBAMYL-D-AMINO ACID AMIDOHYDROLASE
著者Nakai, T, Hasegawa, T, Yamashita, E, Yamamoto, M, Kumasaka, T, Ueki, T, Nanba, H, Ikenaka, Y, Takahashi, S, Sato, M, Tsukihara, T.
登録日2000-04-06
公開日2001-04-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of N-carbamyl-D-amino acid amidohydrolase with a novel catalytic framework common to amidohydrolases.
Structure Fold.Des., 8, 2000
7XW8
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Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAK-418 distomer, FAD-adduct
分子名称: GLYCEROL, Lysine-specific histone demethylase 1A, MAGNESIUM ION, ...
著者Oki, H.
登録日2022-05-26
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Design, synthesis, and structure-activity relationship of TAK-418 and its derivatives as a novel series of LSD1 inhibitors with lowered risk of hematological side effects.
Eur.J.Med.Chem., 239, 2022
4MKN
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Crystal structure of chloroplastic triosephosphate isomerase from Chlamydomonas reinhardtii at 1.1 A of resolution
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Triosephosphate isomerase
著者Fermani, S, Sciabolini, C, Zaffagnini, M, Lemaire, S.D.
登録日2013-09-05
公開日2014-01-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献High-Resolution Crystal Structure and Redox Properties of Chloroplastic Triosephosphate Isomerase from Chlamydomonas reinhardtii.
Mol Plant, 7, 2014
7WJT
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Crystal structure of coiled-coil region of mouse TMEM266
分子名称: Isoform 2 of Transmembrane protein 266
著者Narita, H, Nishikawa, S, Nakagawa, A.
登録日2022-01-07
公開日2022-10-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insight into the function of a unique voltage-sensor protein (TMEM266) and its short form in mouse cerebellum.
Biochem.J., 479, 2022
3AOH
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RNA polymerase-Gfh1 complex (Crystal type 1)
分子名称: Anti-cleavage anti-GreA transcription factor Gfh1, DNA (5'-D(*GP*GP*TP*CP*TP*GP*TP*AP*TP*CP*AP*CP*GP*AP*GP*CP*CP*AP*CP*CP*GP*CP*CP*GP*CP*AP*T)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Tagami, S, Sekine, S, Kumarevel, T, Yamamoto, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2010-09-28
公開日2010-12-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein
Nature, 468, 2010
3AOI
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RNA polymerase-Gfh1 complex (Crystal type 2)
分子名称: Anti-cleavage anti-GreA transcription factor Gfh1, DNA (5'-D(*GP*GP*TP*CP*TP*GP*TP*AP*TP*CP*AP*CP*GP*AP*GP*CP*CP*A*CP*CP*GP*CP*CP*GP*CP*AP*T)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Tagami, S, Sekine, S, Kumarevel, T, Yamamoto, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2010-09-30
公開日2010-12-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein
Nature, 468, 2010

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