7NI0
 
 | | 1918 H1N1 Viral influenza polymerase heterotrimer - Replicase (class 3) | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | 登録日 | 2021-02-11 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
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7NJ5
 | | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8199 core | | 分子名称: | Nb8199 Core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | 登録日 | 2021-02-16 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4.63 Å) | | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
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7NKC
 | | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8207 | | 分子名称: | Nb8207, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | 登録日 | 2021-02-17 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-02-09 | | 実験手法 | ELECTRON MICROSCOPY (4.46 Å) | | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
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7NIR
 | | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8191 core | | 分子名称: | Nanobody8191 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | 登録日 | 2021-02-13 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-02-09 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
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7NK2
 | | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8202 core | | 分子名称: | Nanobody8202, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | 登録日 | 2021-02-17 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-02-09 | | 実験手法 | ELECTRON MICROSCOPY (4.84 Å) | | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
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7NFT
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7NHC
 | | 1918 H1N1 Viral influenza polymerase heterotrimer - Endonuclease ordered (Class2b) | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | 登録日 | 2021-02-10 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
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7NJ4
 | | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8198 core | | 分子名称: | Nb8198 Core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | 登録日 | 2021-02-16 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-02-09 | | 実験手法 | ELECTRON MICROSCOPY (5.84 Å) | | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
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7NIL
 | | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8190 core | | 分子名称: | Nanobody8190 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | 登録日 | 2021-02-12 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-02-09 | | 実験手法 | ELECTRON MICROSCOPY (5.01 Å) | | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
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7NJ3
 | | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8196 core | | 分子名称: | Nanobody8196 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ... | | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | 登録日 | 2021-02-15 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-02-09 | | 実験手法 | ELECTRON MICROSCOPY (4.48 Å) | | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
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7NK4
 | | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8203 core | | 分子名称: | Nanobody 8203, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | 登録日 | 2021-02-17 | | 公開日 | 2021-12-01 | | 最終更新日 | 2022-02-09 | | 実験手法 | ELECTRON MICROSCOPY (5.32 Å) | | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
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7NK8
 | | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8205 core | | 分子名称: | Nb8205, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ... | | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | 登録日 | 2021-02-17 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (5.34 Å) | | 主引用文献 | Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
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7NT8
 | | Influenza virus H3N2 nucleoprotein - R416A mutant | | 分子名称: | Glutathione S-transferase class-mu 26 kDa isozyme,Nucleoprotein | | 著者 | Keown, J.R, Knight, M.L, Grimes, J.M, Fodor, E. | | 登録日 | 2021-03-09 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Structure of an H3N2 influenza virus nucleoprotein.
Acta Crystallogr.,Sect.F, 77, 2021
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2J7N
 | | Structure of the RNAi polymerase from Neurospora crassa | | 分子名称: | GLYCEROL, MAGNESIUM ION, RNA-DEPENDENT RNA POLYMERASE | | 著者 | Salgado, P.S, Koivunen, M.R.L, Makeyev, E.V, Bamford, D.H, Stuart, D.I, Grimes, J.M. | | 登録日 | 2006-10-13 | | 公開日 | 2006-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The Structure of an Rnai Polymerase Links RNA Silencing and Transcription.
Plos Biol., 4, 2006
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2J7O
 | | STRUCTURE OF THE RNAI POLYMERASE FROM NEUROSPORA CRASSA | | 分子名称: | MAGNESIUM ION, RNA DEPENDENT RNA POLYMERASE | | 著者 | Salgado, P.S, Koivunen, M.R.L, Makeyev, E.V, Bamford, D.H, Stuart, D.I, Grimes, J.M. | | 登録日 | 2006-10-13 | | 公開日 | 2006-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | The Structure of an Rnai Polymerase Links RNA Silencing and Transcription.
Plos Biol., 4, 2006
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8R60
 | | 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | 登録日 | 2023-11-19 | | 公開日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | | 主引用文献 | 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide
To Be Published
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2JLF
 | | STRUCTURAL EXPLANATION FOR THE ROLE OF MN IN THE ACTIVITY OF PHI6 RNA- DEPENDENT RNA POLYMERASE | | 分子名称: | MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE | | 著者 | Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. | | 登録日 | 2008-09-08 | | 公開日 | 2008-11-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase.
Nucleic Acids Res., 36, 2008
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2JH9
 | | The structure of bluetongue virus VP4 reveals a multifunctional RNA- capping production-line | | 分子名称: | GUANINE, GUANOSINE-5'-TRIPHOSPHATE, VP4 CORE PROTEIN | | 著者 | Sutton, G, Grimes, J.M, Stuart, D.I, Roy, P. | | 登録日 | 2007-02-21 | | 公開日 | 2007-04-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Bluetongue Virus Vp4 is an RNA-Capping Assembly Line.
Nat.Struct.Mol.Biol., 14, 2007
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2JL9
 | | Structural explanation for the role of Mn in the activity of phi6 RNA- dependent RNA polymerase | | 分子名称: | RNA-DIRECTED RNA POLYMERASE | | 著者 | Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. | | 登録日 | 2008-09-05 | | 公開日 | 2008-11-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase.
Nucleic Acids Res., 36, 2008
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2JHA
 | | The structure of bluetongue virus VP4 reveals a multifunctional RNA- capping production-line | | 分子名称: | DIGUANOSINE-5'-TRIPHOSPHATE, GUANINE, VP4 CORE PROTEIN | | 著者 | Sutton, G, Grimes, J.M, Stuart, D.I, Roy, P. | | 登録日 | 2007-02-21 | | 公開日 | 2007-04-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Bluetongue Virus Vp4 is an RNA-Capping Assembly Line.
Nat.Struct.Mol.Biol., 14, 2007
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8R65
 | | 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | | 登録日 | 2023-11-20 | | 公開日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.23 Å) | | 主引用文献 | 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains
To Be Published
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1UVJ
 | | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 7nt RNA | | 分子名称: | 5'-R(*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase | | 著者 | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | | 登録日 | 2004-01-21 | | 公開日 | 2004-02-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
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1UVK
 | | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 dead-end complex | | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | | 登録日 | 2004-01-21 | | 公開日 | 2004-02-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
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8PX5
 | | Structure of the RNA recognition motif (RRM) of Seb1 from S. pombe., solved at wavelength 2.75 A | | 分子名称: | Rpb7-binding protein seb1 | | 著者 | El Omari, K, Duman, R, Mykhaylyk, V, Orr, C, Wittmann, S, Renner, M, Grimes, J.M, Wagner, A. | | 登録日 | 2023-07-22 | | 公開日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Experimental phasing opportunities for macromolecular crystallography at very long wavelengths.
Commun Chem, 6, 2023
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1UVM
 | | The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 5NT RNA conformation A | | 分子名称: | 5'-R(*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase | | 著者 | Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M. | | 登録日 | 2004-01-21 | | 公開日 | 2004-02-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
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