5K7V
| Computational Design of Self-Assembling Cyclic Protein Homooligomers | 分子名称: | Designed protein HR00C3 | 著者 | Sankaran, B, Zwart, P.H, Fallas, J.A, Pereira, J.H, Ueda, G, Baker, D. | 登録日 | 2016-05-26 | 公開日 | 2017-04-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.165 Å) | 主引用文献 | Computational design of self-assembling cyclic protein homo-oligomers. Nat Chem, 9, 2017
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5KBA
| Computational Design of Self-Assembling Cyclic Protein Homooligomers | 分子名称: | Designed protein ANK1C2 | 著者 | Sankaran, B, Zwart, P.H, Fallas, J.A, Pereira, J.H, Ueda, G, Baker, D. | 登録日 | 2016-06-02 | 公開日 | 2017-04-12 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | 主引用文献 | Computational design of self-assembling cyclic protein homo-oligomers. Nat Chem, 9, 2017
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5KWD
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7UWZ
| NMR solution structure of the De novo designed small beta-barrel protein 33_bp_sh3 | 分子名称: | De novo designed small beta-barrel protein 33_bp_sh3 | 著者 | Peterson, F.C, Kim, D.E, Jensen, D.R, Saleem, A, Chow, C.M, Volkman, B.F, Baker, D. | 登録日 | 2022-05-04 | 公開日 | 2023-03-22 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | De novo design of small beta barrel proteins. Proc.Natl.Acad.Sci.USA, 120, 2023
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7UWY
| NMR solution structure of the De novo designed small beta-barrel protein 29_bp_sh3 | 分子名称: | De novo designed small beta-barrel protein 29_bp_sh3 | 著者 | Peterson, F.C, Kim, D.E, Jensen, D.R, Saleem, A, Chow, C.M, Volkman, B.F, Baker, D. | 登録日 | 2022-05-04 | 公開日 | 2023-03-22 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | De novo design of small beta barrel proteins. Proc.Natl.Acad.Sci.USA, 120, 2023
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6E5C
| Solution NMR structure of a de novo designed double-stranded beta-helix | 分子名称: | De novo beta protein | 著者 | Marcos, E, Chidyausiku, T.M, McShan, A, Evangelidis, T, Nerli, S, Sgourakis, N, Tripsianes, K, Baker, D. | 登録日 | 2018-07-19 | 公開日 | 2018-11-07 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | De novo design of a non-local beta-sheet protein with high stability and accuracy. Nat. Struct. Mol. Biol., 25, 2018
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2FLD
| I-MsoI Re-Designed for Altered DNA Cleavage Specificity | 分子名称: | 5'-D(*CP*GP*GP*AP*AP*CP*GP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*CP*TP*TP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*AP*AP*GP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*CP*GP*TP*TP*CP*CP*G)-3', CALCIUM ION, ... | 著者 | Ashworth, J, Duarte, C.M, Havranek, J.J, Sussman, D, Monnat, R.J, Stoddard, B.L, Baker, D. | 登録日 | 2006-01-05 | 公開日 | 2006-06-06 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Computational redesign of endonuclease DNA binding and cleavage specificity. Nature, 441, 2006
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5KCI
| Crystal Structure of HTC1 | 分子名称: | GLYCEROL, SULFATE ION, Uncharacterized protein YPL067C, ... | 著者 | Martin, R.M, Horowitz, S, Koepnick, B, Cooper, S, Flatten, J, Rogawski, D.S, Koropatkin, N.M, Beinlich, F.R.M, Players, F, Students, U.M, Popovic, Z, Baker, D, Khatib, F, Bardwell, J.C.A. | 登録日 | 2016-06-06 | 公開日 | 2016-09-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.833 Å) | 主引用文献 | Determining crystal structures through crowdsourcing and coursework. Nat Commun, 7, 2016
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7CBC
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1VJQ
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6N4N
| Crystal structure of the designed protein DNCR2/danoprevir/NS3a complex | 分子名称: | (2R,6S,12Z,13aS,14aR,16aS)-6-[(tert-butoxycarbonyl)amino]-14a-[(cyclopropylsulfonyl)carbamoyl]-5,16-dioxo-1,2,3,5,6,7,8 ,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-2-yl 4-fluoro-2H-isoindole-2-carboxylate, NS3 protease, Rosetta-designed danoprevir/NS3a complex reader 2, ... | 著者 | Wang, Z, Foight, G.W, Baker, D, Maly, D.J. | 登録日 | 2018-11-19 | 公開日 | 2019-09-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Multi-input chemical control of protein dimerization for programming graded cellular responses. Nat.Biotechnol., 37, 2019
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7RMY
| De Novo designed tunable protein pockets, D_3-337 | 分子名称: | De Novo designed tunable homodimer, D_3-337 | 著者 | Bera, A.K, Hicks, D.R, Kang, A, Sankaran, B, Baker, D. | 登録日 | 2021-07-28 | 公開日 | 2022-08-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | 主引用文献 | De novo design of protein homodimers containing tunable symmetric protein pockets. Proc.Natl.Acad.Sci.USA, 119, 2022
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7RMX
| Structure of De Novo designed tunable symmetric protein pockets | 分子名称: | Tunable symmetric protein, D_3_212 | 著者 | Bera, A.K, Hicks, D.R, Kang, A, Sankaran, B, Baker, D. | 登録日 | 2021-07-28 | 公開日 | 2022-08-03 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | De novo design of protein homodimers containing tunable symmetric protein pockets. Proc.Natl.Acad.Sci.USA, 119, 2022
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1YSB
| Yeast Cytosine Deaminase Triple Mutant | 分子名称: | CALCIUM ION, Cytosine deaminase, ZINC ION | 著者 | Korkegian, A, Black, M.E, Baker, D, Stoddard, B.L. | 登録日 | 2005-02-08 | 公開日 | 2005-05-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Computational thermostabilization of an enzyme. Science, 308, 2005
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1YSD
| Yeast Cytosine Deaminase Double Mutant | 分子名称: | CALCIUM ION, Cytosine deaminase, ZINC ION | 著者 | Korkegian, A, Black, M.E, Baker, D, Stoddard, B.L. | 登録日 | 2005-02-08 | 公開日 | 2005-05-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Computational thermostabilization of an enzyme. Science, 308, 2005
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2LPB
| Structure of the complex of the central activation domain of Gcn4 bound to the mediator co-activator domain 1 of Gal11/med15 | 分子名称: | General control protein GCN4, Mediator of RNA polymerase II transcription subunit 15 | 著者 | Brzovic, P.S, Heikaus, C.C, Kisselev, L, Vernon, R, Herbig, E, Pacheco, D, Warfield, L, Littlefield, P, Baker, D, Klevit, R.E, Hahn, S. | 登録日 | 2012-02-07 | 公開日 | 2012-02-22 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex. Mol.Cell, 44, 2011
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6UDR
| S2 symmetric peptide design number 3 crystal form 1, Lurch | 分子名称: | S2-3, Lurch crystal form 1 | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-19 | 公開日 | 2020-09-23 | 最終更新日 | 2020-12-02 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
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6UF7
| S2 symmetric peptide design number 5, Uncle Fester | 分子名称: | S2-5, Uncle Fester | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-23 | 公開日 | 2020-12-02 | 実験手法 | X-RAY DIFFRACTION (0.8 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
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6UF8
| S2 symmetric peptide design number 6, London Bridge | 分子名称: | S2-6, London Bridge | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-23 | 公開日 | 2020-12-02 | 実験手法 | X-RAY DIFFRACTION (0.8 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
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6UFU
| C2 symmetric peptide design number 1, Zappy, crystal form 1 | 分子名称: | C2-1, Zappy, crystal form 1 | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-25 | 公開日 | 2020-12-02 | 実験手法 | X-RAY DIFFRACTION (1.101 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
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6UG3
| C3 symmetric peptide design number 1, Sporty, crystal form 1 | 分子名称: | C3-1, Sporty, crystal form 1, ... | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-25 | 公開日 | 2020-12-02 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
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6UGC
| C3 symmetric peptide design number 3 | 分子名称: | C3-3 cyclic peptide design, CADMIUM ION, SODIUM ION | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-26 | 公開日 | 2020-12-02 | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
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6UD9
| S2 symmetric peptide design number 2, Morticia | 分子名称: | S2-2, Morticia | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-19 | 公開日 | 2020-09-23 | 最終更新日 | 2020-12-02 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
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6UCX
| S2 symmetric peptide design number 1, Wednesday | 分子名称: | S2-1, Wednesday, trifluoroacetic acid | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-18 | 公開日 | 2020-09-23 | 最終更新日 | 2021-07-28 | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
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6UDZ
| S2 symmetric peptide design number 4 crystal form 1, Pugsley | 分子名称: | S2-4, Pusgley crystal form 1, trifluoroacetic acid | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-20 | 公開日 | 2020-09-23 | 最終更新日 | 2020-12-02 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
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