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1EAB
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ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX
分子名称: 6,8-DIMERCAPTO-OCTANOIC ACID AMIDE, COENZYME A, DIHYDROLIPOYL-TRANSACETYLASE
著者Mattevi, A, Hol, W.G.J.
登録日1992-12-16
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
Biochemistry, 32, 1993
1EAD
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ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX
分子名称: DIHYDROLIPOYL-TRANSACETYLASE, OXIDIZED COENZYME A
著者Mattevi, A, Hol, W.G.J.
登録日1992-12-16
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
Biochemistry, 32, 1993
1S5B
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Cholera holotoxin with an A-subunit Y30S mutation Form 3
分子名称: Cholera enterotoxin, A chain precursor, SODIUM ION, ...
著者O'Neal, C.J, Amaya, E.I, Jobling, M.G, Holmes, R.K, Hol, W.G.
登録日2004-01-20
公開日2004-04-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism
Biochemistry, 43, 2004
1EAE
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BU of 1eae by Molmil
ATOMIC STRUCTURE OF THE CUBIC CORE OF THE PYRUVATE DEHYDROGENASE MULTIENZYME COMPLEX
分子名称: 6,8-DIMERCAPTO-OCTANOIC ACID AMIDE, DIHYDROLIPOYL-TRANSACETYLASE
著者Mattevi, A, Hol, W.G.J.
登録日1992-12-16
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).
Biochemistry, 32, 1993
1S5E
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BU of 1s5e by Molmil
Cholera holotoxin, Crystal form 1
分子名称: Cholera enterotoxin, A chain precursor, SODIUM ION, ...
著者O'Neal, C.J, Amaya, E.I, Jobling, M.G, Holmes, R.K, Hol, W.G.
登録日2004-01-20
公開日2004-04-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism
Biochemistry, 43, 2004
1G3S
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CYS102SER DTXR
分子名称: DIPHTHERIA TOXIN REPRESSOR
著者Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J.
登録日2000-10-25
公開日2001-10-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
1G3Y
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ARG80ALA DTXR
分子名称: DIPHTHERIA TOXIN REPRESSOR, ZINC ION
著者Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J.
登録日2000-10-25
公開日2001-10-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
1FWZ
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GLU20ALA DTXR
分子名称: DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION
著者Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J.
登録日2000-09-25
公開日2001-09-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
1G3T
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CYS102SER DTXR
分子名称: DIPHTHERIA TOXIN REPRESSOR
著者Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J.
登録日2000-10-25
公開日2001-10-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
1G3W
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CD-CYS102SER DTXR
分子名称: CADMIUM ION, DIPHTHERIA TOXIN REPRESSOR, SULFATE ION
著者Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J.
登録日2000-10-25
公開日2001-10-25
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
4EG6
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Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor Chem 1325
分子名称: 4-{4-[(1H-benzimidazol-2-ylmethyl)amino]-6-(2-chloro-4-methoxyphenoxy)pyrimidin-2-yl}piperazin-2-one, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Koh, C.Y, Kim, J.E, Shibata, S, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J.
登録日2012-03-30
公開日2012-09-12
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4EG1
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Trypanosoma brucei methionyl-tRNA synthetase in complex with substrate Methionine
分子名称: GLYCEROL, METHIONINE, Methionyl-tRNA synthetase, ...
著者Koh, C.Y, Kim, J.E, Shibata, S, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J.
登録日2012-03-30
公開日2012-09-12
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4EGA
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BU of 4ega by Molmil
Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor Chem 1320
分子名称: 2-({3-[(3,5-dibromo-2-methoxybenzyl)amino]propyl}amino)quinolin-4(1H)-one, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Koh, C.Y, Kim, J.E, Shibata, S, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J.
登録日2012-03-30
公開日2012-09-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.698 Å)
主引用文献Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4EG3
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Trypanosoma brucei methionyl-tRNA synthetase in complex with product methionyl-adenylate
分子名称: GLYCEROL, Methionyl-tRNA synthetase, putative, ...
著者Koh, C.Y, Kim, J.E, Shibata, S, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J.
登録日2012-03-30
公開日2012-09-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4EG7
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Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor Chem 1331
分子名称: DIMETHYL SULFOXIDE, GLYCEROL, METHIONINE, ...
著者Koh, C.Y, Kim, J.E, Shibata, S, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J.
登録日2012-03-30
公開日2012-09-12
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.747 Å)
主引用文献Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4EG5
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Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor Chem 1312
分子名称: 2-({3-[(3,5-dichlorobenzyl)amino]propyl}amino)quinolin-4(1H)-one, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Koh, C.Y, Kim, J.E, Shibata, S, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J.
登録日2012-03-30
公開日2012-09-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4GGN
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Malaria invasion machinery protein complex
分子名称: Myosin A tail domain interacting protein MTIP, Myosin-A
著者Khamrui, S, Turley, S, Bergman, L.W, Hol, W.G.J.
登録日2012-08-06
公開日2013-07-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献The structure of the D3 domain of Plasmodium falciparum myosin tail interacting protein MTIP in complex with a nanobody.
Mol.Biochem.Parasitol., 190, 2013
4EG4
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Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor Chem 1289
分子名称: 2-({3-[(3,5-dibromo-2-ethoxybenzyl)amino]propyl}amino)quinolin-4(1H)-one, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Koh, C.Y, Kim, J.E, Shibata, S, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J.
登録日2012-03-30
公開日2012-09-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.151 Å)
主引用文献Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
4GFT
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Malaria invasion machinery protein-Nanobody complex
分子名称: 1,2-ETHANEDIOL, Myosin A tail domain interacting protein, Nanobody
著者Khamrui, S, Turley, S, Pardon, E, Steyaert, J, Verlinde, C, Fan, E, Bergman, L.W, Hol, W.G.J.
登録日2012-08-03
公開日2013-07-03
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The structure of the D3 domain of Plasmodium falciparum myosin tail interacting protein MTIP in complex with a nanobody.
Mol.Biochem.Parasitol., 190, 2013
4EG8
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Trypanosoma brucei methionyl-tRNA synthetase in complex with compound Chem 89
分子名称: 2-aminoquinolin-8-ol, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Koh, C.Y, Kim, J.E, Shibata, S, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J.
登録日2012-03-30
公開日2012-09-12
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.596 Å)
主引用文献Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection.
Structure, 20, 2012
1IVY
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PHYSIOLOGICAL DIMER HPP PRECURSOR
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rudenko, G, Bonten, E, D'Azzo, A, Hol, W.G.J.
登録日1996-06-12
公開日1997-04-21
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three-dimensional structure of the human 'protective protein': structure of the precursor form suggests a complex activation mechanism.
Structure, 3, 1995
1DPD
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BU of 1dpd by Molmil
CRYSTALLOGRAPHIC AND ENZYMATIC INVESTIGATIONS ON THE ROLE OF SER558, HIS610 AND ASN614 IN THE CATALYTIC MECHANISM OF AZOTOBACTER VINELANDII DIHYDROLIPOAMIDE ACETYLTRANSFERASE (E2P)
分子名称: DIHYDROLIPOYL-TRANSACETYLASE
著者Hendle, J, Hol, W.G.J.
登録日1995-02-03
公開日1995-04-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystallographic and enzymatic investigations on the role of Ser558, His610, and Asn614 in the catalytic mechanism of Azotobacter vinelandii dihydrolipoamide acetyltransferase (E2p).
Biochemistry, 34, 1995
1DPC
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CRYSTALLOGRAPHIC AND ENZYMATIC INVESTIGATIONS ON THE ROLE OF SER558, HIS610 AND ASN614 IN THE CATALYTIC MECHANISM OF AZOTOBACTER VINELANDII DIHYDROLIPOAMIDE ACETYLTRANSFERASE (E2P)
分子名称: DIHYDROLIPOYL-TRANSACETYLASE
著者Hendle, J, Hol, W.G.J.
登録日1995-02-03
公開日1995-04-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystallographic and enzymatic investigations on the role of Ser558, His610, and Asn614 in the catalytic mechanism of Azotobacter vinelandii dihydrolipoamide acetyltransferase (E2p).
Biochemistry, 34, 1995
1DPB
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CRYSTALLOGRAPHIC AND ENZYMATIC INVESTIGATIONS ON THE ROLE OF SER558, HIS610 AND ASN614 IN THE CATALYTIC MECHANISM OF AZOTOBACTER VINELANDII DIHYDROLIPOAMIDE ACETYLTRANSFERASE (E2P)
分子名称: DIHYDROLIPOYL-TRANSACETYLASE
著者Hendle, J, Hol, W.G.J.
登録日1995-02-03
公開日1995-04-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystallographic and enzymatic investigations on the role of Ser558, His610, and Asn614 in the catalytic mechanism of Azotobacter vinelandii dihydrolipoamide acetyltransferase (E2p).
Biochemistry, 34, 1995
1XDN
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BU of 1xdn by Molmil
High resolution crystal structure of an editosome enzyme from trypanosoma brucei: RNA editing ligase 1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA editing ligase MP52
著者Deng, J, Schnaufer, A, Salavati, R, Stuart, K.D, Hol, W.G.
登録日2004-09-07
公開日2004-12-07
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献High resolution crystal structure of a key editosome enzyme from Trypanosoma brucei: RNA editing ligase 1.
J.Mol.Biol., 343, 2004

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