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4M8T
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BU of 4m8t by Molmil
RSK2 T493M C-Terminal Kinase Domain in complex with 3-(3-(1H-pyrazol-4-yl)phenyl)-2-cyanoacrylamide
分子名称: (2E)-2-cyano-3-[3-(1H-pyrazol-4-yl)phenyl]prop-2-enamide, Ribosomal protein S6 kinase alpha-3, SODIUM ION
著者Miller, R.M, Taunton, J.
登録日2013-08-13
公開日2014-10-22
最終更新日2014-11-26
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Covalent docking of large libraries for the discovery of chemical probes.
Nat.Chem.Biol., 10, 2014
4LDI
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BU of 4ldi by Molmil
Low resolution structure of Ebola virus M241R mutant
分子名称: Matrix protein VP40
著者Bornholdt, Z.A, Ableson, D.M, Saphire, E.O.
登録日2013-06-24
公開日2013-08-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.15 Å)
主引用文献Structural Rearrangement of Ebola Virus VP40 Begets Multiple Functions in the Virus Life Cycle.
Cell(Cambridge,Mass.), 154, 2013
1ZAG
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BU of 1zag by Molmil
HUMAN ZINC-ALPHA-2-GLYCOPROTEIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chirino, A.J, Sanchez, L.M, Bjorkman, P.J.
登録日1999-02-02
公開日1999-03-31
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human ZAG, a fat-depleting factor related to MHC molecules.
Science, 283, 1999
5A8H
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BU of 5a8h by Molmil
cryo-ET subtomogram averaging of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB OF BROADLY NEUTRALIZING ANTIBODY 17B, FAB OF BROADLY NEUTRALIZING ANTIBODY 8ANC195 VARIANT G52K5, ...
著者Scharf, L, Wang, H, Gao, H, Chen, S, McDowall, A, Bjorkman, P.
登録日2015-07-15
公開日2015-08-05
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (23 Å)
主引用文献Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.
Cell, 162, 2015
5A7X
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negative stain EM of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB OF BROADLY NEUTRALIZING ANTIBODY 17B, FAB OF BROADLY NEUTRALIZING ANTIBODY 8ANC195, ...
著者Scharf, L, Wang, H, Gao, H, Chen, S, McDowall, A, Bjorkman, P.
登録日2015-07-10
公開日2015-08-05
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (17 Å)
主引用文献Broadly Neutralizing Antibody 8Anc195 Recognizes Closed and Open States of HIV-1 Env.
Cell(Cambridge,Mass.), 162, 2015
5AMN
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BU of 5amn by Molmil
The Discovery of 2-Substituted Phenol Quinazolines as Potent and Selective RET Kinase Inhibitors
分子名称: 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE, FORMIC ACID, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET
著者Newton, R, Bowler, K, Burns, E.M, Chapman, P, Fairweather, E, Fritzl, S, Goldberg, K, Hamilton, N.M, Holt, S.V, Hopkins, G.V, Jones, S.D, Jordan, A.M, Lyons, A, McDonald, N.Q, Maguire, L.A, Mould, D.P, Purkiss, A.G, Small, H.F, Stowell, A, Thomson, G.J, Waddell, I.D, Waszkowycz, B, Watson, A.J, Ogilvie, D.J.
登録日2015-03-11
公開日2016-02-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity.
Eur J Med Chem, 112, 2016
2KTX
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BU of 2ktx by Molmil
COMPLETE KALIOTOXIN FROM ANDROCTONUS MAURETANICUS MAURETANICUS, NMR, 18 STRUCTURES
分子名称: KALIOTOXIN
著者Gairi, M, Romi, R, Fernandez, I, Rochat, H, Martin-Eauclaire, M.-F, Van Rietschtoten, J, Pons, M, Giralt, E.
登録日1997-02-27
公開日1997-06-16
最終更新日2017-12-20
実験手法SOLUTION NMR
主引用文献3D structure of kaliotoxin: is residue 34 a key for channel selectivity?
J.Pept.Sci., 3, 1997
2K9I
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BU of 2k9i by Molmil
NMR structure of plasmid copy control protein ORF56 from sulfolobus islandicus
分子名称: Uncharacterized protein ORF56
著者Weininger, U, Balbach, J.
登録日2008-10-15
公開日2009-10-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure-Based Stability Analysis of an Extremely Stable Dimeric DNA Binding Protein from Sulfolobus islandicus
Biochemistry, 48, 2009
1HVD
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BU of 1hvd by Molmil
STRUCTURAL AND ELECTROPHYSIOLOGICAL ANALYSIS OF ANNEXIN V MUTANTS. MUTAGENESIS OF HUMAN ANNEXIN V, AN IN VITRO VOLTAGE-GATED CALCIUM CHANNEL, PROVIDES INFORMATION ABOUT THE STRUCTURAL FEATURES OF THE ION PATHWAY, THE VOLTAGE SENSOR AND THE ION SELECTIVITY FILTER
分子名称: ANNEXIN V, CALCIUM ION
著者Burger, A, Huber, R.
登録日1994-06-29
公開日1995-03-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and electrophysiological analysis of annexin V mutants. Mutagenesis of human annexin V, an in vitro voltage-gated calcium channel, provides information about the structural features of the ion pathway, the voltage sensor and the ion selectivity filter
J.Mol.Biol., 237, 1994
1HVF
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BU of 1hvf by Molmil
STRUCTURAL AND ELECTROPHYSIOLOGICAL ANALYSIS OF ANNEXIN V MUTANTS. MUTAGENESIS OF HUMAN ANNEXIN V, AN IN VITRO VOLTAGE-GATED CALCIUM CHANNEL, PROVIDES INFORMATION ABOUT THE STRUCTURAL FEATURES OF THE ION PATHWAY, THE VOLTAGE SENSOR AND THE ION SELECTIVITY FILTER
分子名称: ANNEXIN V, CALCIUM ION, SULFATE ION
著者Burger, A, Huber, R.
登録日1994-06-29
公開日1995-03-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and electrophysiological analysis of annexin V mutants. Mutagenesis of human annexin V, an in vitro voltage-gated calcium channel, provides information about the structural features of the ion pathway, the voltage sensor and the ion selectivity filter
J.Mol.Biol., 237, 1994
1HVG
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BU of 1hvg by Molmil
STRUCTURAL AND ELECTROPHYSIOLOGICAL ANALYSIS OF ANNEXIN V MUTANTS. MUTAGENESIS OF HUMAN ANNEXIN V, AN IN VITRO VOLTAGE-GATED CALCIUM CHANNEL, PROVIDES INFORMATION ABOUT THE STRUCTURAL FEATURES OF THE ION PATHWAY, THE VOLTAGE SENSOR AND THE ION SELECTIVITY FILTER
分子名称: ANNEXIN V
著者Burger, A, Huber, R.
登録日1994-06-29
公開日1995-03-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and electrophysiological analysis of annexin V mutants. Mutagenesis of human annexin V, an in vitro voltage-gated calcium channel, provides information about the structural features of the ion pathway, the voltage sensor and the ion selectivity filter
J.Mol.Biol., 237, 1994
1U79
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BU of 1u79 by Molmil
Crystal structure of AtFKBP13
分子名称: FKBP-type peptidyl-prolyl cis-trans isomerase 3
著者Gopalan, G, Swaminathan, K.
登録日2004-08-03
公開日2004-09-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural analysis uncovers a role for redox in regulating FKBP13, an immunophilin of the chloroplast thylakoid lumen
Proc.Natl.Acad.Sci.Usa, 101, 2004
2PVG
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BU of 2pvg by Molmil
Crystal srtucture of the binary complex between ferredoxin and ferredoxin:thioredoxin reductase
分子名称: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1, Ferredoxin-thioredoxin reductase, ...
著者Dai, S.
登録日2007-05-09
公開日2007-07-10
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural snapshots along the reaction pathway of ferredoxin-thioredoxin reductase.
Nature, 448, 2007
2PVO
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BU of 2pvo by Molmil
Crystal srtucture of the ternary complex between thioredoxin f, ferredoxin, and ferredoxin: thioredoxin reductase
分子名称: FE2/S2 (INORGANIC) CLUSTER, Ferredoxin-1, Ferredoxin-thioredoxin reductase, ...
著者Dai, S.
登録日2007-05-09
公開日2007-07-10
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural snapshots along the reaction pathway of ferredoxin-thioredoxin reductase.
Nature, 448, 2007
8B6K
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BU of 8b6k by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing dCTP in the polymerase active site
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
著者Parkash, V, Johansson, E.
登録日2022-09-27
公開日2023-10-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B67
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BU of 8b67 by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing CTP in the polymerase active site
分子名称: ACETATE ION, CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, ...
著者Parkash, V, Johansson, E.
登録日2022-09-26
公開日2023-10-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B7E
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BU of 8b7e by Molmil
The crystal structure of N828V variant of DNA Pol Epsilon containing UTP in the polymerase active site
分子名称: CALCIUM ION, DNA polymerase epsilon catalytic subunit A, GLYCEROL, ...
著者Parkash, V, Johansson, E.
登録日2022-09-29
公開日2023-10-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B79
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BU of 8b79 by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing UTP in the polymerase active site
分子名称: ACETATE ION, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
著者Parkash, V, Johansson, E.
登録日2022-09-29
公開日2023-10-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B77
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BU of 8b77 by Molmil
The crystal structure of N828V variant of DNA Pol Epsilon containing dATP in the polymerase active site
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
著者Parkash, V, Johansson, E.
登録日2022-09-29
公開日2023-10-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
8B76
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BU of 8b76 by Molmil
The crystal structure of M644G variant of DNA Pol Epsilon containing dTTP in the polymerase active site
分子名称: ACETATE ION, CALCIUM ION, DNA polymerase epsilon catalytic subunit A, ...
著者Parkash, V, Johansson, E.
登録日2022-09-28
公開日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A sensor complements the steric gate when DNA polymerase epsilon discriminates ribonucleotides.
Nucleic Acids Res., 2023
4GJ2
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BU of 4gj2 by Molmil
Tyk2 (JH1) in complex with 2,6-dichloro-N-[2-({[(1R,2R)-2-fluorocyclopropyl]carbonyl}amino)pyridin-4-yl]benzamide
分子名称: 2,6-dichloro-N-[2-({[(1R,2R)-2-fluorocyclopropyl]carbonyl}amino)pyridin-4-yl]benzamide, Non-receptor tyrosine-protein kinase TYK2
著者Ultsch, M.H.
登録日2012-08-09
公開日2013-05-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Lead Optimization of a 4-Aminopyridine Benzamide Scaffold To Identify Potent, Selective, and Orally Bioavailable TYK2 Inhibitors.
J.Med.Chem., 56, 2013
6O9R
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BU of 6o9r by Molmil
The capsid structure of empty AAVrh.10 particles
分子名称: Capsid protein VP1
著者Mietzsch, M, Agbandje-McKenna, M.
登録日2019-03-14
公開日2019-12-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.75 Å)
主引用文献Comparative Analysis of the Capsid Structures of AAVrh.10, AAVrh.39, and AAV8.
J.Virol., 94, 2020
4GII
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BU of 4gii by Molmil
Tyk2 (JH1) in complex with 2,6-dichloro-4-cyano-N-{2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}benzamide
分子名称: 2,6-dichloro-4-cyano-N-{2-[(cyclopropylcarbonyl)amino]pyridin-4-yl}benzamide, Non-receptor tyrosine-protein kinase TYK2
著者Ultsch, M.H.
登録日2012-08-08
公開日2013-05-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Lead Optimization of a 4-Aminopyridine Benzamide Scaffold To Identify Potent, Selective, and Orally Bioavailable TYK2 Inhibitors.
J.Med.Chem., 56, 2013
6OV1
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Structure of Staphylococcus aureus RNase P protein mutant with defective mRNA degradation activity
分子名称: Ribonuclease P protein component
著者Ha, L, Colquhoun, J, Noinaj, N, Das, C, Dunman, P, Flaherty, D.P.
登録日2019-05-06
公開日2020-12-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Genetic and biochemical characterization of Staphylococcus aureus RnpA
To Be Published
8GKV
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Crystal structure of anti-adaptor IraP that regulates RpoS proteolysis
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Shaw, G.X, Gan, J, Suburaman, P, Battesti, A, Zhou, Y.N, Wickner, S, Gottesman, S, Ji, X.
登録日2023-03-20
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.351 Å)
主引用文献Structural and functional study of anti-adaptor IraP-mediated regulation of RpoS proteolysis
to be published

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