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5MN7
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BU of 5mn7 by Molmil
S. aureus FtsZ 12-316 F138A GTP Closed form (3FCm)
分子名称: Cell division protein FtsZ, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Wagstaff, J.M, Tsim, M, Kureisaite-Ciziene, D, Lowe, J.
登録日2016-12-12
公開日2017-01-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A Polymerization-Associated Structural Switch in FtsZ That Enables Treadmilling of Model Filaments.
MBio, 8, 2017
1TPW
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BU of 1tpw by Molmil
TRIOSEPHOSPHATE ISOMERASE DRINKS WATER TO KEEP HEALTHY
分子名称: PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Stock, A.M, Narayana, N, Xuong, Ng.H, Knowles, J.R, Petsko, G.A, Ringe, D.
登録日1994-11-07
公開日1995-04-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The role of water in the catalytic efficiency of triosephosphate isomerase.
Biochemistry, 38, 1999
5NJP
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BU of 5njp by Molmil
Mix-and-diffuse serial synchrotron crystallography: structure of N,N',N''-Triacetylchitotriose bound to Lysozyme with 1s time-delay, phased with 1HEW
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Lysozyme C, ...
著者Oberthuer, D, Meents, A, Beyerlein, K.R, Chapman, H.N, Lieseke, J.
登録日2017-03-29
公開日2017-10-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mix-and-diffuse serial synchrotron crystallography.
IUCrJ, 4, 2017
2X53
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BU of 2x53 by Molmil
Structure of the phage p2 baseplate in its activated conformation with Sr
分子名称: ORF15, ORF16, PUTATIVE RECEPTOR BINDING PROTEIN, ...
著者Sciara, G, Bebeacua, C, Bron, P, Tremblay, D, Ortiz-Lombardia, M, Lichiere, J, van Heel, M, Campanacci, V, Moineau, S, Cambillau, C.
登録日2010-02-05
公開日2010-02-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structure of Lactococcal Phage P2 Baseplate and its Mechanism of Activation.
Proc.Natl.Acad.Sci.USA, 107, 2010
1MPZ
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BU of 1mpz by Molmil
NMR solution structure of native Viperidae lebetina obtusa protein
分子名称: Obtustatin
著者Moreno-Murciano, M.P, Monleon, D, Marcinkiewicz, C, Calvete, J.J, Celda, B.
登録日2002-09-13
公開日2003-02-11
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of the Non-RGD Disintegrin Obtustatin
J.Mol.Biol., 329, 2003
5MQE
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BU of 5mqe by Molmil
Crystal structure of CREBBP bromodomain complexed with CBP006
分子名称: 4-bromanyl-~{N}-methyl-1~{H}-pyrrole-2-carboxamide, CREB-binding protein
著者Zhu, J, Spiliotopoulos, D, Caflisch, A.
登録日2016-12-20
公開日2017-04-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain.
Bioorg. Med. Chem. Lett., 27, 2017
5MGE
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BU of 5mge by Molmil
Crystal structure of BAZ2B bromodomain in complex with 1-methylpyridine derivative 1
分子名称: Bromodomain adjacent to zinc finger domain protein 2B, ethyl 4-chloranyl-1-methyl-6-oxidanylidene-pyridine-3-carboxylate
著者Lolli, G, Spiliotopoulos, D, Caflisch, A.
登録日2016-11-21
公開日2017-04-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Discovery of BAZ2A bromodomain ligands.
Eur J Med Chem, 139, 2017
5MQK
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BU of 5mqk by Molmil
Crystal structure of CREBBP bromodomain complexed with CBP019
分子名称: 1-(1-methylindol-3-yl)ethanone, CREB-binding protein
著者Zhu, J, Spiliotopoulos, D, Caflisch, A.
登録日2016-12-20
公開日2017-04-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Virtual screen to NMR (VS2NMR): Discovery of fragment hits for the CBP bromodomain.
Bioorg. Med. Chem. Lett., 27, 2017
5MGH
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BU of 5mgh by Molmil
Crystal structure of pathogenic mutants of human mitochodnrial PheRS
分子名称: PHENYLALANINE, Phenylalanine--tRNA ligase, mitochondrial
著者Kartvelishvili, E, Tworowski, D, Vernon, H, Chrzanowska-Lightowlers, Z, Moor, N, Wang, J, Wong, L.-J, Safro, M.
登録日2016-11-21
公開日2017-05-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Kinetic and structural changes in HsmtPheRS, induced by pathogenic mutations in human FARS2.
Protein Sci., 26, 2017
2WPT
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BU of 2wpt by Molmil
The crystal structure of Im2 in complex with colicin E9 DNase
分子名称: COLICIN-E2 IMMUNITY PROTEIN, COLICIN-E9, GLYCEROL, ...
著者Meenan, N.A, Sharma, A, Fleishman, S.J, Macdonald, C.J, Boetzel, R, Moore, G.R, Baker, D, Kleanthous, C.
登録日2009-08-10
公開日2010-06-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献The Structural and Energetic Basis for High Selectivity in a High-Affinity Protein-Protein Interaction.
Proc.Natl.Acad.Sci.USA, 107, 2010
5MQM
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BU of 5mqm by Molmil
Glycoside hydrolase BT_0986
分子名称: CALCIUM ION, D-rhamnopyranose tetrazole, Glycosyl hydrolases family 2, ...
著者Basle, A, Ndeh, D, Rogowski, A, Cartmell, A, Luis, A.S, Venditto, I, Labourel, A, Gilbert, H.J.
登録日2016-12-20
公開日2017-03-22
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Complex pectin metabolism by gut bacteria reveals novel catalytic functions.
Nature, 544, 2017
2X2R
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BU of 2x2r by Molmil
Crystal structure of human kinesin Eg5 in complex with (R)-2-amino-3-((4-chlorophenyl)diphenylmethylthio)propanoic acid
分子名称: (2R)-2-AMINO-3-[(2R)-2-METHYL-1,1-DIPHENYL-BUTYL]SULFANYL-PROPANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KIF11, ...
著者Kaan, H.Y.K, Weiss, J, Menger, D, Ulaganathan, V, Laggner, C, Popowycz, F, Joseph, B, Kozielski, F.
登録日2010-01-15
公開日2011-01-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-Activity Relationship and Multidrug Resistance Study of New S-Trityl-L-Cysteine Derivatives as Inhibitors of Eg5.
J.Med.Chem., 54, 2011
5MIF
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BU of 5mif by Molmil
Crystal structure of carboxyl esterase 2 (TmelEST2) from mycorrhizal fungus Tuber melanosporum
分子名称: 'Carboxyl esterase 2, FRAGMENT OF TRITON X-100
著者Zanotti, G, Vallese, F, Cavazzini, D, Ottonello, S.
登録日2016-11-28
公開日2017-08-23
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.141 Å)
主引用文献A family of archaea-like carboxylesterases preferentially expressed in the symbiotic phase of the mycorrhizal fungus Tuber melanosporum.
Sci Rep, 7, 2017
1MOW
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BU of 1mow by Molmil
E-DreI
分子名称: 5'-D(*CP*CP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*AP*GP*TP*TP*CP*CP*GP*GP*CP*G)-3', 5'-D(*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP*GP*G)-3', GLYCEROL, ...
著者Chevalier, B.S, Kortemme, T, Chadsey, M.S, Baker, D, Monnat Jr, R.J, Stoddard, B.L.
登録日2002-09-10
公開日2002-11-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Design, Activity and Structure of a Highly Specific Artificial Endonuclease
Mol.Cell, 10, 2002
1MPU
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BU of 1mpu by Molmil
Crystal Structure of the free human NKG2D immunoreceptor
分子名称: NKG2-D type II integral membrane protein, PHOSPHATE ION
著者McFarland, B.J, Kortemme, T, Baker, D, Strong, R.K.
登録日2002-09-12
公開日2003-04-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Symmetry Recognizing Asymmetry: Analysis of the Interactions between the C-Type Lectin-like Immunoreceptor NKG2D and MHC Class I-like Ligands
Structure, 11, 2003
5MKD
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BU of 5mkd by Molmil
Crystal structure of Bacillus subtilis Ywea
分子名称: Ywea
著者Carrington, J, van Aalten, D.
登録日2016-12-03
公開日2017-01-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Crystal structure of Bacillus subtilis Ywea
To Be Published
5MMI
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BU of 5mmi by Molmil
Structure of the large subunit of the chloroplast ribosome
分子名称: 23S ribosomal RNA, 4.5S ribosomal RNA, 50S ribosomal protein 6, ...
著者Bieri, P, Leibundgut, M, Saurer, M, Boehringer, D, Ban, N.
登録日2016-12-10
公開日2017-01-11
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The complete structure of the chloroplast 70S ribosome in complex with translation factor pY.
EMBO J., 36, 2017
1LXL
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BU of 1lxl by Molmil
NMR STRUCTURE OF BCL-XL, AN INHIBITOR OF PROGRAMMED CELL DEATH, MINIMIZED AVERAGE STRUCTURE
分子名称: BCL-XL
著者Muchmore, S.W, Sattler, M, Liang, H, Meadows, R.P, Harlan, J.E, Yoon, H.S, Nettesheim, D, Chang, B.S, Thompson, C.B, Wong, S.L, Ng, S.C, Fesik, S.W.
登録日1996-04-04
公開日1997-04-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death.
Nature, 381, 1996
2X95
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BU of 2x95 by Molmil
Crystal structure of AnCE-lisinopril-tryptophan analogue, lisW-S complex
分子名称: (S)-1-N2-(1-CARBOXY-3-PHENYLPROPYL)-L-LYSYL-L-TRYPTOPHAN, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Akif, M, Georgiadis, D, Mahajan, A, Dive, V, Sturrock, E.D, Isaac, R.E, Acharya, K.R.
登録日2010-03-14
公開日2010-06-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs.
J.Mol.Biol., 400, 2010
5MUT
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BU of 5mut by Molmil
Crystal structure of potent human Dihydroorotate Dehydrogenase inhibitors based on hydroxylated azole scaffolds
分子名称: 2-methyl-5-oxidanyl-~{N}-[2,3,5,6-tetrakis(fluoranyl)-4-phenyl-phenyl]-1,2,3-triazole-4-carboxamide, ACETATE ION, CHLORIDE ION, ...
著者Goyal, P, Andersson, M, Moritzer, A.C, Sainas, S, Pippione, A.C, Boschi, D, Al-Kadaraghi, S, Lolli, M, Friemann, R.
登録日2017-01-14
公開日2017-03-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds.
Eur J Med Chem, 129, 2017
2WNG
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BU of 2wng by Molmil
complete extracellular structure of human signal regulatory protein (SIRP) alpha
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1
著者Hatherley, D, Graham, S.C, Harlos, K, Stuart, D.I, Barclay, A.N.
登録日2009-07-09
公開日2009-07-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structure of Signal-Regulatory Protein Alpha: A Link to Antigen Receptor Evolution.
J.Biol.Chem., 284, 2009
5MUY
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BU of 5muy by Molmil
Structure of a C-terminal domain of a reptarenavirus L protein with m7GTP
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, L protein
著者Rosenthal, M, Gogrefe, N, Reguera, J, Vogel, D, Rauschenberger, B, Cusack, S, Gunther, S, Reindl, S.
登録日2017-01-14
公開日2017-05-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural insights into reptarenavirus cap-snatching machinery.
PLoS Pathog., 13, 2017
5MA9
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BU of 5ma9 by Molmil
GFP-binding DARPin fusion gc_R11
分子名称: 1,2-ETHANEDIOL, Green fluorescent protein, R11
著者Hansen, S, Stueber, J, Ernst, P, Koch, A, Bojar, D, Batyuk, A, Plueckthun, A.
登録日2016-11-03
公開日2017-11-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Design and applications of a clamp for Green Fluorescent Protein with picomolar affinity.
Sci Rep, 7, 2017
2WHU
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Fluorescent Protein mKeima at pH 8.0
分子名称: LARGE STOKES SHIFT FLUORESCENT PROTEIN
著者Violot, S, Carpentier, P, Blanchoin, L, Bourgeois, D.
登録日2009-05-06
公開日2009-08-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Reverse Ph-Dependence of Chromophore Protonation Explains the Large Stokes Shift of the Red Fluorescent Protein Mkeima
J.Am.Chem.Soc., 131, 2009
5MC9
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Crystal structure of the heterotrimeric integrin-binding region of laminin-111
分子名称: CALCIUM ION, Laminin subunit alpha-1, Laminin subunit beta-1, ...
著者Pulido, D, Hohenester, E.
登録日2016-11-09
公開日2017-02-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Crystal Structure of the Heterotrimeric Integrin-Binding Region of Laminin-111.
Structure, 25, 2017

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