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3TM4
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BU of 3tm4 by Molmil
Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosylmethionine
分子名称: S-ADENOSYLMETHIONINE, tRNA (guanine N2-)-methyltransferase Trm14
著者Fislage, M, Roovers, M, Tuszynska, I, Bujnicki, J.M, Droogmans, L, Versees, W.
登録日2011-08-31
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.
Nucleic Acids Res., 40, 2012
8BHJ
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BU of 8bhj by Molmil
Elongating E. coli 70S ribosome containing deacylated tRNA(iMet) in the P-site and Am6AA mRNA codon with cognate dipeptidyl-tRNA(Lys) in the A-site
分子名称: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
著者Koziej, L, Glatt, S.
登録日2022-10-31
公開日2023-08-16
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
1DXK
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BU of 1dxk by Molmil
Metallo-beta-lactamase from Bacillus cereus 569/H/9 C168S mutant
分子名称: BICARBONATE ION, CLASS B BETA-LACTAMASE, ZINC ION
著者Chantalat, L, Duee, E, Dideberg, O.
登録日2000-01-10
公開日2000-08-25
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural effects of the active site mutation cysteine to serine in Bacillus cereus zinc-beta-lactamase.
Protein Sci., 9, 2000
5N5O
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BU of 5n5o by Molmil
Structure of SARS coronavirus main protease in complex with the alpha-ketoamide (S)-N-benzyl-3-((S)-2-cinnamamido-3-cyclopropylpropanamido)-2-oxo-4-((S)-2-oxopyrrolidin-3-yl)butanamide (Cinnamoyl-cyclopropylalanine-GlnLactam-CO-CO-NH-benzyl)
分子名称: (2~{R},3~{S})-3-[[(2~{S})-3-cyclopropyl-2-[[(~{E})-3-phenylprop-2-enoyl]amino]propanoyl]amino]-2-oxidanyl-4-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-~{N}-(phenylmethyl)butanamide, Replicase polyprotein 1ab
著者Zhang, L, Hilgenfeld, R.
登録日2017-02-14
公開日2018-03-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Alpha-ketoamides as broad-spectrum inhibitors of coronavirus and enterovirus replication
To Be Published
8BIM
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BU of 8bim by Molmil
Initiation complex of the E. coli 70S ribosome with mRNA containing AAm6A codon in the A-site
分子名称: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
著者Koziej, L, Glatt, S.
登録日2022-11-02
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.04 Å)
主引用文献Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8X19
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BU of 8x19 by Molmil
Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
登録日2023-11-06
公開日2024-03-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into histone exchange by human SRCAP complex.
Cell Discov, 10, 2024
8BHN
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BU of 8bhn by Molmil
Elongating E. coli 70S ribosome containing deacylated tRNA(iMet) in the P-site and m6AAA mRNA codon with cognate dipeptidyl-tRNA(Lys) in the A-site
分子名称: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
著者Koziej, L, Glatt, S.
登録日2022-10-31
公開日2023-08-16
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
1PJ0
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BU of 1pj0 by Molmil
RIBONUCLEOTIDE REDUCTASE R2-D84E/W48F MUTANT SOAKED WITH FERROUS IONS AT NEUTRAL PH
分子名称: FE (III) ION, MERCURY (II) ION, Ribonucleoside-diphosphate reductase 1 beta chain
著者Voegtli, W.C, Sommerhalter, M, Saleh, L, Baldwin, J, Bollinger Jr, J.M, Rosenzweig, A.C.
登録日2003-05-30
公開日2004-01-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Variable coordination geometries at the diiron(II) active site of ribonucleotide reductase R2.
J.Am.Chem.Soc., 125, 2003
4D6S
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BU of 4d6s by Molmil
crystal structure of human JMJD2D in complex with N-OXALYLGLYCINE and bound 5,6-Dimethylbenzimidazole
分子名称: 1,2-ETHANEDIOL, 5,6-DIMETHYLBENZIMIDAZOLE, DIMETHYL SULFOXIDE, ...
著者Krojer, T, Vollmar, M, Bradley, A, Crawley, L, Szykowska, A, Burgess-Brown, N, Gileadi, C, Johansson, C, Oppermann, U, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F.
登録日2014-11-14
公開日2014-12-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal Structure of Human Jmjd2D in Complex with N-Oxalylglycine and Bound 5,6- Dimethylbenzimidazole
To be Published
8BF7
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BU of 8bf7 by Molmil
Elongating E. coli 70S ribosome containing deacylated tRNA(iMet) in the P-site and AAA mRNA codon with cognate dipeptidyl-tRNA(Lys) in the A-site
分子名称: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
著者Koziej, L, Glatt, S.
登録日2022-10-24
公開日2023-08-16
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.33 Å)
主引用文献Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
3U9D
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BU of 3u9d by Molmil
Crystal Structure of a chimera containing the N-terminal domain (residues 8-24) of drosophila Ciboulot and the C-terminal domain (residues 13-44) of bovine Thymosin-beta4, bound to G-actin-ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Renault, L, Husson, C, Carlier, M.F, Didry, D.
登録日2011-10-18
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献How a single residue in individual beta-thymosin/WH2 domains controls their functions in actin assembly.
Embo J., 31, 2012
3U9Y
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BU of 3u9y by Molmil
Crystal structure of human tankyrase 2 catalytic domain in complex with olaparib
分子名称: 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one, GLYCEROL, SULFATE ION, ...
著者Narwal, M, Lehtio, L.
登録日2011-10-20
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of selective inhibition of human tankyrases.
J.Med.Chem., 55, 2012
8BGH
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BU of 8bgh by Molmil
Elongating E. coli 70S ribosome containing acylated tRNA(iMet) in the P-site and AAA mRNA codon in the A-site after uncompleted di-peptide formation
分子名称: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
著者Koziej, L, Glatt, S.
登録日2022-10-27
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
8BIL
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BU of 8bil by Molmil
Initiation complex of the E. coli 70S ribosome with mRNA containing AAA codon in the A-site.
分子名称: 16S rRNA RRSB-RRNA, 23S rRNA RRLG-RRNA, 30S ribosomal protein S10, ...
著者Koziej, L, Glatt, S.
登録日2022-11-02
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.04 Å)
主引用文献Modulation of translational decoding by m 6 A modification of mRNA.
Nat Commun, 14, 2023
1E1P
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BU of 1e1p by Molmil
Human prion protein variant S170N
分子名称: PRION PROTEIN
著者Calzolai, L, Lysek, D.A, Guntert, P, Von Schroetter, C, Zahn, R, Riek, R, Wuthrich, K.
登録日2000-05-09
公開日2000-07-20
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献NMR Structures of Three Single-Residue Variants of the Human Prion Protein
Proc.Natl.Acad.Sci.USA, 97, 2000
5O4N
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BU of 5o4n by Molmil
Apo HcgC from Methanococcus maripaludis soaked with SAH and pyridinol
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 6-carboxy methyl-4-hydroxy-2-pyridinol, DIMETHYL SULFOXIDE, ...
著者Wagner, T, Bai, L, Xu, T, Hu, X, Ermler, U, Shima, S.
登録日2017-05-29
公開日2017-07-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A Water-Bridged H-Bonding Network Contributes to the Catalysis of the SAM-Dependent C-Methyltransferase HcgC.
Angew. Chem. Int. Ed. Engl., 56, 2017
8BJH
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BU of 8bjh by Molmil
chimera of the inactive ExoY Nucleotidyl Cyclase domain from Vibrio nigripulchritudo MARTX toxin, with the double mutation K3528M and K3535I, fused to a proline-Rich-Domain (PRD) and profilin, bound to Latrunculin B-ADP-Mg-actin
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-DIPHOSPHATE, Actin, ...
著者Teixeira-Nunes, M, Renault, L, Retailleau, P.
登録日2022-11-04
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.
Plos Pathog., 19, 2023
3UBF
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BU of 3ubf by Molmil
Crystal structure of Drosophila N-cadherin EC1-3, I
分子名称: CALCIUM ION, Neural-cadherin, ZINC ION
著者Jin, X, Walker, M.A, Shapiro, L.
登録日2011-10-24
公開日2011-12-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of Drosophila N-cadherin ectodomain regions reveal a widely used class of Ca2+-free interdomain linkers.
Proc.Natl.Acad.Sci.USA, 109, 2012
5XP7
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BU of 5xp7 by Molmil
C-Src in complex with ATP-CHCl
分子名称: GLYCEROL, MAGNESIUM ION, Proto-oncogene tyrosine-protein kinase Src, ...
著者Guo, M, Dai, S, Duan, Y, Chen, L, Chen, Y.
登録日2017-06-01
公開日2017-09-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.012 Å)
主引用文献Remarkably Stereospecific Utilization of ATP alpha , beta-Halomethylene Analogues by Protein Kinases.
J. Am. Chem. Soc., 139, 2017
8BN1
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BU of 8bn1 by Molmil
The structures of Ace2 in complex with bicyclic peptide inhibitor
分子名称: 1-[3,5-bis(3-bromanylpropanoyl)-1,3,5-triazinan-1-yl]-3-bromanyl-propan-1-one, ALA-CYS-VAL-ARG-SER-4PH-CYS-SER-SER-LEU-LEU-PRO-ARG-ILE-HIS-CYS-ALA-NH2, Processed angiotensin-converting enzyme 2, ...
著者Brear, P, Lulla, A, Harman, M, Dods, R, Chen, L, Bezerra, G, Demydchuk, Y, Stanway, S, Hyvonen, M.
登録日2022-11-11
公開日2023-09-20
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structure-Guided Chemical Optimization of Bicyclic Peptide ( Bicycle ) Inhibitors of Angiotensin-Converting Enzyme 2.
J.Med.Chem., 66, 2023
6GA7
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BU of 6ga7 by Molmil
BACTERIORHODOPSIN, 240FS STATE, REAL-SPACE REFINED AGAINST 10% EXTRAPOLATED MAP
分子名称: 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ...
著者Nass Kovacs, G, Colletier, J.-P, Gruenbein, M.L, Stensitzki, T, Batyuk, A, Carbajo, S, Doak, R.B, Ehrenberg, D, Foucar, L, Gasper, R, Gorel, A, Hilpert, M, Kloos, M, Koglin, J, Reinstein, J, Roome, C.M, Schlesinger, R, Seaberg, M, Shoeman, R.L, Stricker, M, Boutet, S, Haacke, S, Heberle, J, Domratcheva, T, Schlichting, I.
登録日2018-04-11
公開日2019-04-24
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Three-dimensional view of ultrafast dynamics in photoexcited bacteriorhodopsin.
Nat Commun, 10, 2019
1PDW
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BU of 1pdw by Molmil
Crystal structure of human DJ-1, P 1 21 1 space group
分子名称: DJ-1
著者Tao, X, Tong, L.
登録日2003-05-20
公開日2003-06-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of Human DJ-1, a Protein Associated with Early Onset Parkinson's Disease.
J.Biol.Chem., 278, 2003
8X15
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Structure of nucleosome-bound SRCAP-C in the apo state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
登録日2023-11-06
公開日2024-03-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into histone exchange by human SRCAP complex.
Cell Discov, 10, 2024
8SLW
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BU of 8slw by Molmil
Cryo-EM structure of the rat TRPM5 channel in 2mM calcium, high-4
分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily M member 5
著者Karuppan, S, Schrag, L.G, Jara-Oseguera, A, Zubcevic, L.
登録日2023-04-24
公開日2024-07-03
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural dynamics at cytosolic interprotomer interfaces control gating of a mammalian TRPM5 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
1DO9
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BU of 1do9 by Molmil
SOLUTION STRUCTURE OF OXIDIZED MICROSOMAL RABBIT CYTOCHROME B5. FACTORS DETERMINING THE HETEROGENEOUS BINDING OF THE HEME.
分子名称: CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
著者Banci, L, Bertini, I, Rosato, A, Scacchieri, S.
登録日1999-12-20
公開日2000-01-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of oxidized microsomal rabbit cytochrome b5. Factors determining the heterogeneous binding of the heme.
Eur.J.Biochem., 267, 2000

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