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3APD
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Crystal structure of human PI3K-gamma in complex with CH5108134
分子名称: 5-(2-Morpholin-4-yl-7-pyridin-3-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-ylamine, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION
著者Nakamura, M, Fukami, T.A, Miyazaki, T, Yoshida, M.
登録日2010-10-14
公開日2011-04-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Discovery and biological activity of a novel class I PI3K inhibitor, CH5132799
Bioorg.Med.Chem.Lett., 21, 2011
3APC
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Crystal structure of human PI3K-gamma in complex with CH5132799
分子名称: 5-(7-Methanesulfonyl-2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-ylamine, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION
著者Nakamura, M, Fukami, T.A, Miyazaki, T, Yoshida, M.
登録日2010-10-14
公開日2011-04-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.544 Å)
主引用文献Discovery and biological activity of a novel class I PI3K inhibitor, CH5132799
Bioorg.Med.Chem.Lett., 21, 2011
3APF
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Crystal structure of human PI3K-gamma in complex with CH5039699
分子名称: 3-[7-(1H-benzimidazol-5-yl)-2-(morpholin-4-yl)-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl]phenol, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION
著者Nakamura, M, Fukami, T.A, Miyazaki, T, Yoshida, M.
登録日2010-10-14
公開日2011-04-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Discovery and biological activity of a novel class I PI3K inhibitor, CH5132799
Bioorg.Med.Chem.Lett., 21, 2011
1WFF
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BU of 1wff by Molmil
Solution structure of the zf-AN1 domain from mouse RIKEN cDNA 2810002D23 protein
分子名称: RIKEN cDNA 2810002D23 protein, ZINC ION
著者Tomizawa, T, Kigawa, T, Izumi, K, Yoshida, M, Yamazaki, T, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-26
公開日2004-11-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the zf-AN1 domain from mouse RIKEN cDNA 2810002D23 protein
To be Published
3VOF
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Cellobiohydrolase mutant, CcCel6C D102A, in the closed form
分子名称: Cellobiohydrolase, beta-D-glucopyranose
著者Tamura, M, Miyazaki, T, Tanaka, Y, Yoshida, M, Nishikawa, A, Tonozuka, T.
登録日2012-01-23
公開日2012-03-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Comparison of the structural changes in two cellobiohydrolases, CcCel6A and CcCel6C, from Coprinopsis cinerea - a tweezer-like motion in the structure of CcCel6C
Febs J., 279, 2012
3VOH
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CcCel6A catalytic domain complexed with cellobiose
分子名称: Cellobiohydrolase, beta-D-glucopyranose, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, ...
著者Tamura, M, Miyazaki, T, Tanaka, Y, Yoshida, M, Nishikawa, A, Tonozuka, T.
登録日2012-01-24
公開日2012-03-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Comparison of the structural changes in two cellobiohydrolases, CcCel6A and CcCel6C, from Coprinopsis cinerea - a tweezer-like motion in the structure of CcCel6C
Febs J., 279, 2012
3VOJ
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CcCel6A catalytic domain mutant D164A
分子名称: Cellobiohydrolase
著者Tamura, M, Miyazaki, T, Tanaka, Y, Yoshida, M, Nishikawa, A, Tonozuka, T.
登録日2012-01-24
公開日2012-03-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Comparison of the structural changes in two cellobiohydrolases, CcCel6A and CcCel6C, from Coprinopsis cinerea - a tweezer-like motion in the structure of CcCel6C
Febs J., 279, 2012
3VOG
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Catalytic domain of the cellobiohydrolase, CcCel6A, from Coprinopsis cinerea
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cellobiohydrolase
著者Tamura, M, Miyazaki, T, Tanaka, Y, Yoshida, M, Nishikawa, A, Tonozuka, T.
登録日2012-01-24
公開日2012-03-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Comparison of the structural changes in two cellobiohydrolases, CcCel6A and CcCel6C, from Coprinopsis cinerea - a tweezer-like motion in the structure of CcCel6C
Febs J., 279, 2012
3VOI
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CcCel6A catalytic domain complexed with p-nitrophenyl beta-D-cellotrioside
分子名称: 4-nitrophenyl beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranoside, Cellobiohydrolase, MAGNESIUM ION
著者Tamura, M, Miyazaki, T, Tanaka, Y, Yoshida, M, Nishikawa, A, Tonozuka, T.
登録日2012-01-24
公開日2012-03-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Comparison of the structural changes in two cellobiohydrolases, CcCel6A and CcCel6C, from Coprinopsis cinerea - a tweezer-like motion in the structure of CcCel6C
Febs J., 279, 2012
3W9A
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Crystal structure of the catalytic domain of the glycoside hydrolase family 131 protein from Coprinopsis cinerea
分子名称: GLYCEROL, Putative uncharacterized protein
著者Miyazaki, T, Tanaka, Y, Tamura, M, Yoshida, M, Nishikawa, A, Tonozuka, T.
登録日2013-04-01
公開日2013-05-22
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal structure of the N-terminal domain of a glycoside hydrolase family 131 protein from Coprinopsis cinerea
Febs Lett., 587, 2013
4Y6L
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BU of 4y6l by Molmil
Human SIRT2 in complex with myristoylated peptide (H3K9myr)
分子名称: NAD-dependent protein deacetylase sirtuin-2, ZINC ION, peptide THR-ALA-ARG-MYK-SER-THR-GLY
著者Kudo, N, Ito, A, Yoshida, M.
登録日2015-02-13
公開日2016-01-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Kinetic and Structural Basis for Acyl-Group Selectivity and NAD(+) Dependence in Sirtuin-Catalyzed Deacylation.
Biochemistry, 54, 2015
4Y6Q
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Human SIRT2 in complex with 2-O-myristoyl-ADP-ribose
分子名称: NAD-dependent protein deacetylase sirtuin-2, ZINC ION, [(2S,3R,4R,5R)-5-[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-2,4-bis(oxidanyl)oxolan-3-yl] tetradecanoate
著者Kudo, N, Ito, A, Yoshida, M.
登録日2015-02-13
公開日2016-01-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Kinetic and Structural Basis for Acyl-Group Selectivity and NAD(+) Dependence in Sirtuin-Catalyzed Deacylation.
Biochemistry, 54, 2015
1IXZ
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Crystal structure of the FtsH ATPase domain from Thermus thermophilus
分子名称: ATP-dependent metalloprotease FtsH, MERCURY (II) ION, SULFATE ION
著者Niwa, H, Tsuchiya, D, Makyio, H, Yoshida, M, Morikawa, K.
登録日2002-07-10
公開日2002-11-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Hexameric ring structure of the ATPase domain of the membrane-integrated metalloprotease FtsH from Thermus thermophilus HB8
Structure, 10, 2002
4Y6O
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Human SIRT2 in complex with myristoylated peptide (TNF-alphaK20myr)
分子名称: NAD-dependent protein deacetylase sirtuin-2, ZINC ION, peptide LEU-PRO-LYS-MYK-THR-GLY-GLY
著者Kudo, N, Ito, A, Yoshida, M.
登録日2015-02-13
公開日2016-01-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Kinetic and Structural Basis for Acyl-Group Selectivity and NAD(+) Dependence in Sirtuin-Catalyzed Deacylation.
Biochemistry, 54, 2015
1IY1
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Crystal structure of the FtsH ATPase domain with ADP from Thermus thermophilus
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent metalloprotease FtsH
著者Niwa, H, Tsuchiya, D, Makyio, H, Yoshida, M, Morikawa, K.
登録日2002-07-10
公開日2002-11-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Hexameric ring structure of the ATPase domain of the membrane-integrated metalloprotease FtsH from Thermus thermophilus HB8
Structure, 10, 2002
1IYG
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BU of 1iyg by Molmil
Solution structure of RSGI RUH-001, a Fis1p-like and CGI-135 homologous domain from a mouse cDNA
分子名称: Hypothetical protein (2010003O14)
著者Ohashi, W, Hirota, H, Yamazaki, T, Koshiba, S, Hamada, T, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2002-08-14
公開日2003-02-14
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of RSGI RUH-001, a Fis1p-like and CGI-135 homologous domain from a mouse cDNA
To be Published
1IY2
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BU of 1iy2 by Molmil
Crystal structure of the FtsH ATPase domain from Thermus thermophilus
分子名称: ATP-dependent metalloprotease FtsH, SULFATE ION
著者Niwa, H, Tsuchiya, D, Makyio, H, Yoshida, M, Morikawa, K.
登録日2002-07-10
公開日2002-11-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Hexameric ring structure of the ATPase domain of the membrane-integrated metalloprotease FtsH from Thermus thermophilus HB8
Structure, 10, 2002
1J3D
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Solution structure of the C-terminal domain of the HMGB2
分子名称: High mobility group protein 2
著者Kurita, J, Shimahara, H, Yoshida, M, Tate, S.
登録日2003-01-23
公開日2004-05-25
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Strucutral comparison of two HMG-boxes in the non-histone protein HMG-2 with in the HMG-1
To be Published
1J3C
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Solution structure of the C-terminal domain of the HMGB2
分子名称: High mobility group protein 2
著者Kurita, J, Shimahara, H, Yoshida, M, Tate, S.
登録日2003-01-23
公開日2004-05-25
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Strucutral comparison of two HMG-boxes in the non-histone protein HMG-2 with in the HMG-1
To be Published
1J3X
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Solution structure of the N-terminal domain of the HMGB2
分子名称: High mobility group protein 2
著者Kurita, J, Shimahara, H, Yoshida, M, Tate, S.
登録日2003-02-19
公開日2004-06-29
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Strucutral comparison of two HMG-boxes in the non-histone protein HMG-2 with in the HMG-1
To be Published
1IY0
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BU of 1iy0 by Molmil
Crystal structure of the FtsH ATPase domain with AMP-PNP from Thermus thermophilus
分子名称: ATP-dependent metalloprotease FtsH, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Niwa, H, Tsuchiya, D, Makyio, H, Yoshida, M, Morikawa, K.
登録日2002-07-10
公開日2002-11-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Hexameric ring structure of the ATPase domain of the membrane-integrated metalloprotease FtsH from Thermus thermophilus HB8
Structure, 10, 2002
1L5H
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FeMo-cofactor Deficient Nitrogenase MoFe Protein
分子名称: CALCIUM ION, FE(8)-S(7) CLUSTER, nitrogenase molybdenum-iron protein alpha chain, ...
著者Schmid, B, Ribbe, M.W, Einsle, O, Yoshida, M, Thomas, L.M, Dean, D.R, Rees, D.C, Burgess, B.K.
登録日2002-03-06
公開日2002-04-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of a cofactor-deficient nitrogenase MoFe protein.
Science, 296, 2002
1M1Y
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Chemical Crosslink of Nitrogenase MoFe Protein and Fe Protein
分子名称: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, FE(8)-S(7) CLUSTER, ...
著者Schmid, B, Einsle, O, Chiu, H.J, Willing, A, Yoshida, M, Howard, J.B, Rees, D.C.
登録日2002-06-20
公開日2003-02-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Biochemical and Structural Characterization of the Crosslinked Complex of Nitrogenase: Comparison to the ADP-AlF4- Stabilized Structure
Biochemistry, 41, 2002
1M34
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Nitrogenase Complex From Azotobacter Vinelandii Stabilized By ADP-Tetrafluoroaluminate
分子名称: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
著者Schmid, B, Einsle, O, Chiu, H.-J, Willing, A, Yoshida, M, Howard, J.B, Rees, D.C.
登録日2002-06-27
公開日2003-02-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Biochemical and Structural Characterization of the Crosslinked Complex of Nitrogenase: Comparison to the ADP-AlF4 Stabilized structure
Biochemistry, 41, 2002
1M1N
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Nitrogenase MoFe protein from Azotobacter vinelandii
分子名称: 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, FE(7)-MO-S(9)-N CLUSTER, ...
著者Einsle, O, Tezcan, F.A, Andrade, S.L.A, Schmid, B, Yoshida, M, Howard, J.B, Rees, D.C.
登録日2002-06-19
公開日2002-09-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Nitrogenase MoFe-protein at 1.16 A resolution: a central ligand in the FeMo-cofactor.
Science, 297, 2002

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