6KTV
 
 | | The structure of EanB complex with hercynine and persulfided Cys412 | | 分子名称: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, CHLORIDE ION, ... | | 著者 | Wu, L, Liu, P.H, Zhou, J.H. | | 登録日 | 2019-08-29 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Single-Step Replacement of an Unreactive C-H Bond by a C-S Bond Using Polysulfide as the Direct Sulfur Source in the Anaerobic Ergothioneine Biosynthesis
Acs Catalysis, 10, 2020
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6KTX
 | | The wildtype structure of EanB | | 分子名称: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... | | 著者 | Wu, L, Liu, P.H, Zhou, J.H. | | 登録日 | 2019-08-29 | | 公開日 | 2020-08-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.189 Å) | | 主引用文献 | Single-Step Replacement of an Unreactive C-H Bond by a C-S Bond Using Polysulfide as the Direct Sulfur Source in the Anaerobic Ergothioneine Biosynthesis
Acs Catalysis, 10, 2020
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6KU1
 | | The structure of EanB/Y353A complex with ergothioneine | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Wu, L, Liu, P.H, Zhou, J.H. | | 登録日 | 2019-08-30 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Single-Step Replacement of an Unreactive C-H Bond by a C-S Bond Using Polysulfide as the Direct Sulfur Source in the Anaerobic Ergothioneine Biosynthesis
Acs Catalysis, 10, 2020
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4AEK
 | | Structural and biochemical characterization of a novel Carbohydrate Binding Module of endoglucanase Cel5A from Eubacterium cellulosolvens | | 分子名称: | ENDOGLUCANASE CEL5A | | 著者 | Luis, A.S, Venditto, I, Prates, J.A.M, Ferreira, L.M.A, Gilbert, H.J, Fontes, C.M.G.A, Najmudin, S. | | 登録日 | 2012-01-11 | | 公開日 | 2013-01-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Understanding How Non-Catalytic Carbohydrate Binding Modules Can Display Specificity for Xyloglucan.
J.Biol.Chem., 288, 2013
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4AFD
 | | Structural and biochemical characterization of a novel Carbohydrate Binding Module of endoglucanase Cel5A from Eubacterium cellulosolvens with a partially bound cellotetraose moeity. | | 分子名称: | ENDOGLUCANASE CEL5A, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Luis, A.S, Venditto, I, Prates, J.A.M, Ferreira, L.M.A, Gilbert, H.J, Fontes, C.M.G.A, Najmudin, S. | | 登録日 | 2012-01-18 | | 公開日 | 2012-12-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | | 主引用文献 | Understanding How Noncatalytic Carbohydrate Binding Modules Can Display Specificity for Xyloglucan.
J.Biol.Chem., 288, 2013
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4AFM
 | | Structural and biochemical characterization of a novel Carbohydrate Binding Module of endoglucanase Cel5A from Eubacterium cellulosolvens. | | 分子名称: | ACETATE ION, ENDOGLUCANASE CEL5A, GLYCEROL | | 著者 | Luis, A.S, Venditto, I, Prates, J.A.M, Ferreira, L.M.A, Gilbert, H.J, Fontes, C.M.G.A, Najmudin, S. | | 登録日 | 2012-01-19 | | 公開日 | 2012-12-19 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Understanding How Non-Catalytic Carbohydrate Binding Modules Can Display Specificity for Xyloglucan.
J.Biol.Chem., 288, 2013
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4AEM
 | | Structural and biochemical characterization of a novel Carbohydrate Binding Module of endoglucanase Cel5A from Eubacterium cellulosolvens | | 分子名称: | ENDOGLUCANASE CEL5A | | 著者 | Luis, A.S, Venditto, I, Prates, J.A.M, Ferreira, L.M.A, Gilbert, H.J, Fontes, C.M.G.A, Najmudin, S. | | 登録日 | 2012-01-11 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Understanding How Non-Catalytic Carbohydrate Binding Modules Can Display Specificity for Xyloglucan
J.Biol.Chem., 288, 2013
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9JSB
 | | guide-bound NbaSPARDA complexes | | 分子名称: | Ago, DREN-APAZ, MAGNESIUM ION, ... | | 著者 | Zhuang, L. | | 登録日 | 2024-09-30 | | 公開日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Target DNA-induced filament formation and nuclease activation of SPARDA complex.
Cell Res., 2025
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9JSP
 | | inactive NbaSPARDA complexes | | 分子名称: | Ago, DNA (5'-D(P*GP*CP*TP*GP*TP*GP*CP*AP*GP*TP*AP*TP*T)-3'), DREN-APAZ, ... | | 著者 | Zhuang, L. | | 登録日 | 2024-09-30 | | 公開日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | | 主引用文献 | Target DNA-induced filament formation and nuclease activation of SPARDA complex.
Cell Res., 2025
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9JT2
 | | substrate-bound NbaSPARDA complexes | | 分子名称: | Ago, DNA (5'-D(*TP*AP*TP*CP*GP*TP*CP*AP*GP*CP*TP*GP*TP*GP*CP*AP*GP*TP*AP*TP*T)-3'), DNA (5'-D(P*GP*AP*TP*AP*CP*TP*AP*C)-3'), ... | | 著者 | Zhuang, L. | | 登録日 | 2024-10-01 | | 公開日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Target DNA-induced filament formation and nuclease activation of SPARDA complex.
Cell Res., 2025
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9JSZ
 | | active NbaSPARDA complexes | | 分子名称: | Ago, DNA (5'-D(*TP*AP*TP*CP*GP*TP*CP*AP*GP*CP*TP*GP*TP*GP*CP*AP*GP*TP*AP*TP*T)-3'), DREN-APAZ, ... | | 著者 | Zhuang, L. | | 登録日 | 2024-10-01 | | 公開日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Target DNA-induced filament formation and nuclease activation of SPARDA complex.
Cell Res., 2025
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8IZE
 | | Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with 4-HMBPP | | 分子名称: | Butyrophilin subfamily 3 member A1, DI(HYDROXYETHYL)ETHER, [(E)-3-(hydroxymethyl)pent-2-enyl] phosphono hydrogen phosphate | | 著者 | Yang, Y.Y, Yi, S.M, Huang, J.W, Chen, C.C, Guo, R.T. | | 登録日 | 2023-04-07 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
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8IZG
 | | Crystal structure of intracellular B30.2 domain of BTN3A1 in complex with 5-HMBPP | | 分子名称: | 1,2-ETHANEDIOL, Butyrophilin subfamily 3 member A1, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Yang, Y.Y, Yi, S.M, Huang, J.W, Chen, C.C, Guo, R.T. | | 登録日 | 2023-04-07 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
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8IXV
 | | Crystal structure of intracellular B30.2 domain of BTN3A in complex with 2Cl-HMBPP | | 分子名称: | 1,2-ETHANEDIOL, Butyrophilin subfamily 3 member A1, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Yang, Y.Y, Yi, S.M, Huang, J.W, Chen, C.C, Guo, R.T. | | 登録日 | 2023-04-03 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
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8IH4
 | | Crystal Structure of Intracellular B30.2 Domain of BTN2A2 Mutant | | 分子名称: | Butyrophilin subfamily 2 member A2 | | 著者 | Yang, Y.Y, Yi, S.M, Zhang, M.T, Chen, C.C, Guo, R.T, Zhang, Y.H. | | 登録日 | 2023-02-22 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
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8IGT
 | | Crystal Structure of Intracellular B30.2 Domain of BTN2A1 | | 分子名称: | Butyrophilin subfamily 2 member A1, ZINC ION | | 著者 | Yuan, L.J, Yang, Y.Y, Li, X, Cai, N.N, Chen, C.C, Guo, R.T, Zhang, Y.H. | | 登録日 | 2023-02-21 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
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8JYE
 | | Crystal Structure of Intracellular B30.2 Domain of BTN3A1 and BTN2A1 in Complex with HMBPP | | 分子名称: | (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, 1,2-ETHANEDIOL, Butyrophilin subfamily 2 member A1, ... | | 著者 | Yuan, L.J, Yang, Y.Y, Li, X, Cai, N.N, Chen, C.-C, Guo, R.-T, Zhang, Y.H. | | 登録日 | 2023-07-03 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
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8JYA
 | | Crystal Structure of Intracellular B30.2 Domain of VpBTN3 in Complex with IPP | | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Butyrophylin 3, SULFATE ION | | 著者 | Yang, Y.Y, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T. | | 登録日 | 2023-07-03 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
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8JYF
 | | Crystal Structure of Intracellular B30.2 Domain of VpBTN3 in Complex with DMAPP | | 分子名称: | Butyrophylin 3, DIMETHYLALLYL DIPHOSPHATE, SULFATE ION | | 著者 | Yang, Y.Y, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T. | | 登録日 | 2023-07-03 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
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8JYC
 | | Crystal Structure of Intracellular B30.2 Domain of BTN3A1 and BTN2A1 in Complex with DMAPP | | 分子名称: | 1,2-ETHANEDIOL, Butyrophilin subfamily 2 member A1, Butyrophilin subfamily 3 member A1, ... | | 著者 | Yuan, L.J, Yang, Y.Y, Li, X, Cai, N.N, Chen, C.-C, Guo, R.-T, Zhang, Y.H. | | 登録日 | 2023-07-03 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
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8JY9
 | | Crystal Structure of Intracellular B30.2 Domain of VpBTN3 in Complex with HMBPP | | 分子名称: | (2E)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate, Butyrophylin 3, SULFATE ION | | 著者 | Yang, Y.Y, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T. | | 登録日 | 2023-07-03 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
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8JYB
 | | Crystal Structure of Intracellular B30.2 Domain of VpBTN3 | | 分子名称: | Butyrophylin 3, SULFATE ION | | 著者 | Yang, Y.Y, Yi, S.M, Zhang, M.T, Huang, J.-W, Chen, C.-C, Guo, R.-T. | | 登録日 | 2023-07-03 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate V gamma 9V delta 2 T cells.
Nature, 621, 2023
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7EW9
 | | GDP-bound KRAS G12D in complex with TH-Z816 | | 分子名称: | 7-(8-methylnaphthalen-1-yl)-4-[(2~{R})-2-methylpiperazin-1-yl]-2-[[(2~{S})-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5~{H}-pyrido[3,4-d]pyrimidine, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | | 著者 | Shen, P, Yang, Y, Yang, Y, Zhang, L, Chen, C.-C, Guo, R.-T. | | 登録日 | 2021-05-25 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge.
Cell Discov, 8, 2022
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7EWB
 | | GDP-bound KRAS G12D in complex with TH-Z835 | | 分子名称: | 4-[(1~{S},5~{R})-3,8-diazabicyclo[3.2.1]octan-3-yl]-7-(8-methylnaphthalen-1-yl)-2-[[(2~{S})-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5~{H}-pyrido[3,4-d]pyrimidine, GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, ... | | 著者 | Shen, P, Yang, Y, Yang, Y, Zhang, L, Chen, C.-C, Guo, R.-T. | | 登録日 | 2021-05-25 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge.
Cell Discov, 8, 2022
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8YB6
 | | Type I-EHNH Cascade complex | | 分子名称: | 61-nt crRNA, CRISPR system Cascade subunit CasC, CRISPR system Cascade subunit CasD, ... | | 著者 | Li, Z. | | 登録日 | 2024-02-11 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems.
Mol.Cell, 84, 2024
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