7UWG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uwg by Molmil](/molmil-images/mine/7uwg) | The crystal structure of the TIR domain-containing protein from Acinetobacter baumannii (AbTir) | 分子名称: | HEXAETHYLENE GLYCOL, Molecular chaperone Tir, SULFATE ION | 著者 | Manik, M.K, Nanson, J.D, Ve, T, Kobe, B. | 登録日 | 2022-05-03 | 公開日 | 2022-09-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling. Science, 377, 2022
|
|
5NUL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5nul by Molmil](/molmil-images/mine/5nul) | CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT: G57T SEMIQUINONE (150K) | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. | 登録日 | 1996-12-20 | 公開日 | 1997-03-12 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes. Biochemistry, 36, 1997
|
|
6NUL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nul by Molmil](/molmil-images/mine/6nul) | CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT: N137A REDUCED (150K) | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. | 登録日 | 1997-01-09 | 公開日 | 1997-03-12 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes. Biochemistry, 36, 1997
|
|
1UXY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1uxy by Molmil](/molmil-images/mine/1uxy) | MURB MUTANT WITH SER 229 REPLACED BY ALA, COMPLEX WITH ENOLPYRUVYL-UDP-N-ACETYLGLUCOSAMINE | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, URIDINE DIPHOSPHO-N-ACETYLENOLPYRUVYLGLUCOSAMINE REDUCTASE, URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID | 著者 | Benson, T.E, Walsh, C.T, Hogle, J.M. | 登録日 | 1996-11-08 | 公開日 | 1997-04-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | X-ray crystal structures of the S229A mutant and wild-type MurB in the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine at 1.8-A resolution. Biochemistry, 36, 1997
|
|
8B1Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8b1y by Molmil](/molmil-images/mine/8b1y) | STRUCTURE OF PORCINE PANCREATIC ELASTASE BOUND TO A FRAGMENT OF A 5-AZAINDAZOLE INHIBITOR | 分子名称: | 1-cyclopropylcarbonylpyrazolo[4,3-c]pyridine-3-carbonitrile, CALCIUM ION, Chymotrypsin-like elastase family member 1, ... | 著者 | Ferraroni, M, Giovannoni, P, Gerace, A. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | X-ray structural study of human neutrophil elastase inhibition with a series of azaindoles, azaindazoles and isoxazolones J.Mol.Struct., 1274, 2023
|
|
7QGM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qgm by Molmil](/molmil-images/mine/7qgm) | |
7QGL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qgl by Molmil](/molmil-images/mine/7qgl) | |
7QGO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qgo by Molmil](/molmil-images/mine/7qgo) | Human CD73 (ecto 5'-nucleotidase) in complex with MRS4602 (a 3-methyl-CMPCP derivative, compound 21 in paper) in the closed state (crystal form III) | 分子名称: | 5'-nucleotidase, ZINC ION, [[(2~{R},3~{S},4~{R},5~{R})-5-[(4~{E})-4-[(4-methoxycarbonylphenyl)methoxyimino]-3-methyl-2-oxidanylidene-pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]methylphosphonic acid | 著者 | Strater, N. | 登録日 | 2021-12-09 | 公開日 | 2022-02-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | 主引用文献 | Structure-Activity Relationship of 3-Methylcytidine-5'-alpha , beta-methylenediphosphates as CD73 Inhibitors. J.Med.Chem., 65, 2022
|
|
7QGA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qga by Molmil](/molmil-images/mine/7qga) | |
5CZB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5czb by Molmil](/molmil-images/mine/5czb) | HCV NS5B IN COMPLEX WITH LIGAND IDX17119-5 | 分子名称: | 1-[4-(7-amino-5-methylpyrazolo[1,5-a]pyrimidin-2-yl)phenyl]-3-{[(R)-(2,4-dimethylphenyl)(methoxy)phosphoryl]amino}-1H-pyrazole-4-carboxylic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | 著者 | Pierra, C, Dousson, C, Augustin, M. | 登録日 | 2015-07-31 | 公開日 | 2016-06-15 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase. Bioorg.Med.Chem.Lett., 26, 2016
|
|
8B49
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8b49 by Molmil](/molmil-images/mine/8b49) | STRUCTURE OF PORCINE PANCREATIC ELASTASE BOUND TO A FRAGMENT (m-toluoylcarbonyl group) OF A 5-AZAINDOLE INHIBITOR | 分子名称: | 1-(3-methylphenyl)carbonylpyrrolo[3,2-c]pyridine-3-carbonitrile, CALCIUM ION, Chymotrypsin-like elastase family member 1, ... | 著者 | Ferraroni, M, Giovannoni, P, Gerace, A. | 登録日 | 2022-09-20 | 公開日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | X-ray structural study of human neutrophil elastase inhibition with a series of azaindoles, azaindazoles and isoxazolones J.Mol.Struct., 1274, 2023
|
|
8B53
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8b53 by Molmil](/molmil-images/mine/8b53) | |
2MP8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mp8 by Molmil](/molmil-images/mine/2mp8) | NMR structure of NKR-5-3B | 分子名称: | NKR-5-3B | 著者 | Rosengren, K.J, Craik, D.J. | 登録日 | 2014-05-13 | 公開日 | 2015-05-13 | 最終更新日 | 2016-06-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Identification, Characterization, and Three-Dimensional Structure of the Novel Circular Bacteriocin, Enterocin NKR-5-3B, from Enterococcus faecium Biochemistry, 54, 2015
|
|
2FDX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fdx by Molmil](/molmil-images/mine/2fdx) | CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT N137A OXIDIZED | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. | 登録日 | 1996-12-24 | 公開日 | 1997-04-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes. Biochemistry, 36, 1997
|
|
2FAX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fax by Molmil](/molmil-images/mine/2fax) | CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT: N137A OXIDIZED (150K) | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. | 登録日 | 1996-12-24 | 公開日 | 1997-03-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes. Biochemistry, 36, 1997
|
|
2FLV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2flv by Molmil](/molmil-images/mine/2flv) | CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT: G57T REDUCED (150K) | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. | 登録日 | 1996-12-19 | 公開日 | 1997-03-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes. Biochemistry, 36, 1997
|
|
2FOX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fox by Molmil](/molmil-images/mine/2fox) | CLOSTRIDIUM BEIJERINCKII FLAVODOXIN: SEMIQUINONE | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. | 登録日 | 1997-01-08 | 公開日 | 1997-03-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes. Biochemistry, 36, 1997
|
|
2FVX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fvx by Molmil](/molmil-images/mine/2fvx) | CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT: G57T REDUCED (277K) | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. | 登録日 | 1996-12-19 | 公開日 | 1997-03-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes. Biochemistry, 36, 1997
|
|
7LD0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ld0 by Molmil](/molmil-images/mine/7ld0) | Cryo-EM structure of ligand-free Human SARM1 | 分子名称: | NAD(+) hydrolase SARM1 | 著者 | Nanson, J.D, Gu, W, Luo, Z, Jia, X, Landsberg, M.J, Kobe, B, Ve, T. | 登録日 | 2021-01-12 | 公開日 | 2021-03-10 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration. Neuron, 109, 2021
|
|
7LCY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lcy by Molmil](/molmil-images/mine/7lcy) | Crystal structure of the ligand-free ARM domain from Drosophila SARM1 | 分子名称: | Isoform B of NAD(+) hydrolase sarm1 | 著者 | Gu, W, Nanson, J.D, Luo, Z, McGuinness, H.Y, Manik, M.K, Jia, X, Ve, T, Kobe, B. | 登録日 | 2021-01-12 | 公開日 | 2021-03-10 | 最終更新日 | 2021-04-21 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration. Neuron, 109, 2021
|
|
7LCZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lcz by Molmil](/molmil-images/mine/7lcz) | Crystal structure of the ARM domain from Drosophila SARM1 in complex with NMN | 分子名称: | 1,2-ETHANEDIOL, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Isoform B of NAD(+) hydrolase sarm1, ... | 著者 | Gu, W, Nanson, J.D, Luo, Z, Jia, X, Manik, M.K, Ve, T, Kobe, B. | 登録日 | 2021-01-12 | 公開日 | 2021-03-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | SARM1 is a metabolic sensor activated by an increased NMN/NAD + ratio to trigger axon degeneration. Neuron, 109, 2021
|
|
3BW7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3bw7 by Molmil](/molmil-images/mine/3bw7) | |
3C0P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c0p by Molmil](/molmil-images/mine/3c0p) | |
4NUL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nul by Molmil](/molmil-images/mine/4nul) | CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT: D58P OXIDIZED | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. | 登録日 | 1996-12-13 | 公開日 | 1997-03-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes. Biochemistry, 36, 1997
|
|
4NLL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nll by Molmil](/molmil-images/mine/4nll) | CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT: G57D OXIDIZED | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | 著者 | Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. | 登録日 | 1996-12-16 | 公開日 | 1997-03-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes. Biochemistry, 36, 1997
|
|