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6VP8
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Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
分子名称: Leucine-rich repeat serine/threonine-protein kinase 2
著者Leschziner, A, Deniston, C, Lahiri, I.
登録日2020-02-01
公開日2020-08-26
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP6
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Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
分子名称: GUANOSINE-5'-DIPHOSPHATE, Leucine-rich repeat serine/threonine-protein kinase 2, MAGNESIUM ION
著者Leschziner, A, Deniston, C, Lahiri, I.
登録日2020-02-01
公開日2020-08-26
最終更新日2020-12-23
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
6VP7
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Cryo-EM structure of the C-terminal half of the Parkinson's Disease-linked protein Leucine Rich Repeat Kinase 2 (LRRK2)
分子名称: Leucine-rich repeat serine/threonine-protein kinase 2
著者Leschziner, A, Deniston, C, Lahiri, I.
登録日2020-02-01
公開日2020-08-26
最終更新日2020-12-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure of LRRK2 in Parkinson's disease and model for microtubule interaction.
Nature, 588, 2020
3CYS
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BU of 3cys by Molmil
DETERMINATION OF THE NMR SOLUTION STRUCTURE OF THE CYCLOPHILIN A-CYCLOSPORIN A COMPLEX
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A
著者Spitzfaden, C, Braun, W, Wider, G, Widmer, H, Wuthrich, K.
登録日1994-02-28
公開日1994-08-31
最終更新日2017-11-01
実験手法SOLUTION NMR
主引用文献Determination of the NMR Solution Structure of the Cyclophilin A-Cyclosporin a Complex.
J.Biomol.NMR, 4, 1994
2GMT
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BU of 2gmt by Molmil
THREE-DIMENSIONAL STRUCTURE OF CHYMOTRYPSIN INACTIVATED WITH (2S) N-ACETYL-L-ALANYL-L-PHENYLALANYL-CHLOROETHYL KETONE: IMPLICATIONS FOR THE MECHANISM OF INACTIVATION OF SERINE PROTEASES BY CHLOROKETONES
分子名称: (2S) N-ACETYL-L-ALANYL-ALPHAL-PHENYLALANYL-CHLOROETHYLKETONE, GAMMA-CHYMOTRYPSIN
著者Kreutter, K, Steinmetz, A.C.U, Liang, T.-C, Prorok, M, Abeles, R, Ringe, D.
登録日1994-09-07
公開日1994-11-01
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Three-dimensional structure of chymotrypsin inactivated with (2S)-N-acetyl-L-alanyl-L-phenylalanyl alpha-chloroethane: implications for the mechanism of inactivation of serine proteases by chloroketones.
Biochemistry, 33, 1994
6QP0
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BU of 6qp0 by Molmil
Crystal structure of Chaetomium thermophilum Kti12 in complex with ADP-AlF3
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, ...
著者Krutyholowa, R, Glatt, S.
登録日2019-02-13
公開日2019-03-13
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.409 Å)
主引用文献Kti12, a PSTK-like tRNA dependent ATPase essential for tRNA modification by Elongator.
Nucleic Acids Res., 47, 2019
4YMH
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Crystal structure of SAH-bound Podospora anserina methyltransferase PaMTH1
分子名称: DI(HYDROXYETHYL)ETHER, Putative SAM-dependent O-methyltranferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Kudlinzki, D, Linhard, V.L, Chatterjee, D, Saxena, K, Sreeramulu, S, Schwalbe, H.
登録日2015-03-06
公開日2015-05-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.876 Å)
主引用文献Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina.
J.Biol.Chem., 290, 2015
4YMG
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Crystal structure of SAM-bound Podospora anserina methyltransferase PaMTH1
分子名称: MAGNESIUM ION, PHOSPHATE ION, Putative SAM-dependent O-methyltranferase, ...
著者Kudlinzki, D, Linhard, V.L, Chatterjee, D, Saxena, K, Sreeramulu, S, Schwalbe, H.
登録日2015-03-06
公開日2015-05-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.899 Å)
主引用文献Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina.
J.Biol.Chem., 290, 2015
7Y7I
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chicken KNL2 in complex with the CENP-A nucleosome
分子名称: Chains: I, Chains: J, Histone H2A type 1-B/E, ...
著者Ariyoshi, M, Jiang, H, Makino, F, Fukagawa, T.
登録日2022-06-22
公開日2022-07-13
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献The cryo-EM structure of the CENP-A nucleosome in complex with ggKNL2.
Biorxiv, 2022
5VWA
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BU of 5vwa by Molmil
Y316F mutant of corn root ferredoxin:NADP+ reductase
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin--NADP reductase, MAGNESIUM ION
著者Kean, K.M, Carpenter, R.A, Hall, A.R, Karplus, P.A.
登録日2017-05-21
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High-resolution studies of hydride transfer in the ferredoxin:NADP(+) reductase superfamily.
FEBS J., 284, 2017
5VW8
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NADP+ soak of Y316S mutant of corn root ferredoxin:NADP+ reductase in alternate space group
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin--NADP reductase, MAGNESIUM ION, ...
著者Kean, K.M, Carpenter, R.A, Hall, A.R, Karplus, P.A.
登録日2017-05-21
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.808 Å)
主引用文献High-resolution studies of hydride transfer in the ferredoxin:NADP(+) reductase superfamily.
FEBS J., 284, 2017
5VW9
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Nicotinamide soak of Y316S mutant of corn root ferredoxin:NADP+ reductase in alternate space group
分子名称: ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin--NADP reductase, ...
著者Kean, K.M, Carpenter, R.A, Hall, A.R, Karplus, P.A.
登録日2017-05-21
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.894 Å)
主引用文献High-resolution studies of hydride transfer in the ferredoxin:NADP(+) reductase superfamily.
FEBS J., 284, 2017
5VW6
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BU of 5vw6 by Molmil
NADP+ soak of Y316A mutant of corn root ferredoxin:NADP+ reductase
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin--NADP reductase, MAGNESIUM ION, ...
著者Kean, K.M, Carpenter, R.A, Hall, A.R, Karplus, P.A.
登録日2017-05-21
公開日2017-08-23
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献High-resolution studies of hydride transfer in the ferredoxin:NADP(+) reductase superfamily.
FEBS J., 284, 2017
4HCZ
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BU of 4hcz by Molmil
PHF1 Tudor in complex with H3K36me3
分子名称: H3L-like histone, PHD finger protein 1
著者Musselman, C.A, Roy, S, Nunez, J, Kutateladze, T.G.
登録日2012-10-01
公開日2012-11-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1.
Nat.Struct.Mol.Biol., 19, 2012
7KXJ
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BU of 7kxj by Molmil
SARS-CoV-2 spike protein in complex with Fab 15033-7, 3-"up", asymmetric
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 15033-7 heavy chain, ...
著者Li, Z, Rini, J.
登録日2020-12-04
公開日2021-02-03
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
J.Mol.Biol., 433, 2021
7KXK
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SARS-CoV-2 spike protein in complex with Fab 15033-7, 2-"up"-1-"down" conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 15033-7 heavy chain, ...
著者Li, Z, Rini, J.
登録日2020-12-04
公開日2021-02-03
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations.
J.Mol.Biol., 433, 2021
1DEP
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BU of 1dep by Molmil
MEMBRANE PROTEIN, NMR, 1 STRUCTURE
分子名称: T345-359
著者Jung, H, Schnackerz, K.D.
登録日1995-08-23
公開日1996-10-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR and circular dichroism studies of synthetic peptides derived from the third intracellular loop of the beta-adrenoceptor.
FEBS Lett., 358, 1995
4QVK
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BU of 4qvk by Molmil
Apo-crystal structure of Podospora anserina methyltransferase PaMTH1
分子名称: 1,2-ETHANEDIOL, PaMTH1 Methyltransferase
著者Kudlinzki, D, Linhard, V.L, Chatterjee, D, Saxena, K, Sreeramulu, S, Schwalbe, H.
登録日2014-07-15
公開日2015-05-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structure and Biophysical Characterization of the S-Adenosylmethionine-dependent O-Methyltransferase PaMTH1, a Putative Enzyme Accumulating during Senescence of Podospora anserina.
J.Biol.Chem., 290, 2015
3LVB
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BU of 3lvb by Molmil
Crystal structure of the Ferredoxin:NADP+ reductase from maize root at 1.7 angstroms - Test Set Withheld
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin-NADP reductase
著者Faber, H.R, Karplus, P.A, Aliverti, A, Ferioli, C, Spinola, M.
登録日2010-02-19
公開日2010-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Biochemical and crystallographic characterization of ferredoxin-NADP(+) reductase from nonphotosynthetic tissues
Biochemistry, 40, 2001
6F2X
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BU of 6f2x by Molmil
Structural characterization of the Mycobacterium tuberculosis Protein Tyrosine Kinase A (PtkA)
分子名称: Protein Tyrosine Kinase A
著者Niesteruk, A, Jonker, H.R.A, Sreeramulu, S, Richter, C, Hutchison, M, Linhard, V, Schwalbe, H.
登録日2017-11-27
公開日2018-07-04
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献The domain architecture of PtkA, the first tyrosine kinase fromMycobacterium tuberculosis, differs from the conventional kinase architecture.
J. Biol. Chem., 293, 2018
1L07
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CONTRIBUTIONS OF HYDROGEN BONDS OF THR 157 TO THE THERMODYNAMIC STABILITY OF PHAGE T4 LYSOZYME
分子名称: T4 LYSOZYME
著者Dao-Pin, S, Faber, R, Alber, T, Matthews, B.W.
登録日1988-02-05
公開日1988-04-16
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Contributions of hydrogen bonds of Thr 157 to the thermodynamic stability of phage T4 lysozyme.
Nature, 330, 1987
2ZQO
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BU of 2zqo by Molmil
Crystal structure of the earthworm R-type lectin C-half in complex with GalNAc
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, 29-kDa galactose-binding lectin, CADMIUM ION, ...
著者Suzuki, R, Kuno, A, Hasegawa, T, Hirabayashi, J, Kasai, K, Momma, M, Fujimoto, Z.
登録日2008-08-13
公開日2008-09-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Sugar-complex structures of the C-half domain of the galactose-binding lectin EW29 from the earthworm Lumbricus terrestris
Acta Crystallogr.,Sect.D, 65, 2009
2ZQN
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Crystal structure of the earthworm R-type lectin C-half in complex with Lactose
分子名称: 29-kDa galactose-binding lectin, IMIDAZOLE, PHOSPHATE ION, ...
著者Suzuki, R, Kuno, A, Hasegawa, T, Hirabayashi, J, Kasai, K, Momma, M, Fujimoto, Z.
登録日2008-08-13
公開日2008-09-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Sugar-complex structures of the C-half domain of the galactose-binding lectin EW29 from the earthworm Lumbricus terrestris
Acta Crystallogr.,Sect.D, 65, 2009
2YJC
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CATHEPSIN L WITH A NITRILE INHIBITOR
分子名称: (2S,4R)-1-[1-(4-chlorophenyl)cyclopropyl]carbonyl-4-(2-chlorophenyl)sulfonyl-N-[1-(iminomethyl)cyclopropyl]pyrrolidine-2-carboxamide, CATHEPSIN L1
著者Banner, D.W, Benz, J.M, Haap, W.
登録日2011-05-19
公開日2011-11-23
最終更新日2011-11-30
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
Chemmedchem, 6, 2011
2YJ9
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CATHEPSIN L WITH A NITRILE INHIBITOR
分子名称: (2S,4R)-4-(2-chlorophenyl)sulfonyl-N-[1-(iminomethyl)cyclopropyl]-1-[1-[4-(trifluoromethyl)phenyl]cyclopropyl]carbonyl-pyrrolidine-2-carboxamide, CATHEPSIN L1, GLYCEROL
著者Banner, D.W, Benz, J.M, Haap, W.
登録日2011-05-19
公開日2011-11-23
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
Chemmedchem, 6, 2011

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