8TLF
| CDCA7 (Mouse) Binds Non-B-form DNA oligo 36-mer (sg C2-Form 2) | 分子名称: | 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, GLYCEROL, ... | 著者 | Horton, J.R, Ren, R, Cheng, X. | 登録日 | 2023-07-26 | 公開日 | 2024-08-21 | 最終更新日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA. Biorxiv, 2023
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8TLG
| CDCA7 (Mouse) Binds Non-B-form 34-mer DNA oligo | 分子名称: | 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (34-MER), ... | 著者 | Horton, J.R, Ren, R, Cheng, X. | 登録日 | 2023-07-26 | 公開日 | 2024-08-21 | 最終更新日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA. Biorxiv, 2023
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8TLH
| CDCA7 (Mouse) Binds Non-B-form 32-mer DNA oligo | 分子名称: | 1,2-ETHANEDIOL, Cell division cycle-associated protein 7, DNA (32-MER), ... | 著者 | Horton, J.R, Ren, R, Cheng, X. | 登録日 | 2023-07-26 | 公開日 | 2024-08-21 | 最終更新日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA. Biorxiv, 2023
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7YJ3
| Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with human ACE2 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | 著者 | Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2022-07-19 | 公開日 | 2023-07-19 | 最終更新日 | 2023-08-02 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants. Nat Commun, 14, 2023
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7YHW
| Cryo-EM structure of SARS-CoV-2 Omicron BA.2.12.1 RBD in complex with human ACE2 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhao, Z.N, Xie, Y.F, Qi, J.X, Gao, G.F. | 登録日 | 2022-07-14 | 公開日 | 2023-07-19 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants. Nat Commun, 14, 2023
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7YV8
| Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with golden hamster ACE2 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike glycoprotein, ... | 著者 | Zhao, Z.N, Xie, Y.F, Chai, Y, Qi, J.X, Gao, G.F. | 登録日 | 2022-08-18 | 公開日 | 2023-07-19 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants. Nat Commun, 14, 2023
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7YVU
| Cryo-EM structure of SARS-CoV-2 Omicron BA.2 RBD in complex with mouse ACE2 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1, ... | 著者 | Zhao, Z.N, Xie, Y.F, Chai, Y, Qi, J.X, Gao, G.F. | 登録日 | 2022-08-19 | 公開日 | 2023-07-19 | 最終更新日 | 2023-08-02 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for receptor binding and broader interspecies receptor recognition of currently circulating Omicron sub-variants. Nat Commun, 14, 2023
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2OK3
| X-ray structure of human cyclophilin J at 2.0 angstrom | 分子名称: | NICKEL (II) ION, Peptidyl-prolyl cis-trans isomerase-like 3 | 著者 | Xia, Z. | 登録日 | 2007-01-15 | 公開日 | 2008-01-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Targeting Cyclophilin J, a novel peptidyl-prolyl isomerase, can induce cellular G1/S arrest and repress the growth of Hepatocellular carcinoma To be Published
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2OJU
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2FDV
| Microsomal P450 2A6 with the inhibitor N-Methyl(5-(pyridin-3-yl)furan-2-yl)methanamine bound | 分子名称: | 1,2-ETHANEDIOL, Cytochrome P450 2A6, N-METHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE, ... | 著者 | Yano, J.K, Stout, C.D, Johnson, E.F. | 登録日 | 2005-12-14 | 公開日 | 2006-11-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Synthetic Inhibitors of Cytochrome P-450 2A6: Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization. J.Med.Chem., 49, 2006
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2FDY
| Microsomal P450 2A6 with the inhibitor Adrithiol bound | 分子名称: | 4,4'-DIPYRIDYL DISULFIDE, Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Yano, J.K, Stout, C.D, Johnson, E.F. | 登録日 | 2005-12-14 | 公開日 | 2006-11-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Synthetic Inhibitors of Cytochrome P-450 2A6: Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization. J.Med.Chem., 49, 2006
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6LA5
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6LB1
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6LA7
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6X9I
| Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*CP*(5CM)P*GP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*G)-R(P*(PYO))-D(P*GP*GP*CP*CP*TP*C)-3'), ... | 著者 | Pathuri, S, Horton, J.R, Cheng, X. | 登録日 | 2020-06-02 | 公開日 | 2021-07-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer, 2, 2021
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6X9K
| Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3685032A | 分子名称: | (2R)-2-{[6-(4-aminopiperidin-1-yl)-3,5-dicyano-4-ethylpyridin-2-yl]sulfanyl}-2-phenylacetamide, 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*CP*(5CM)P*GP*CP*CP*TP*GP*C)-3'), ... | 著者 | Pathuri, S, Horton, J.R, Cheng, X. | 登録日 | 2020-06-02 | 公開日 | 2021-07-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer, 2, 2021
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6X9J
| Human DNMT1(729-1600) Bound to Zebularine-Containing 12mer dsDNA and Inhibitor GSK3830052 | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*GP*GP*CP*(5CM)P*GP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*G)-R(P*(PYO))-D(P*GP*GP*CP*CP*TP*C)-3'), ... | 著者 | Pathuri, S, Horton, J.R, Cheng, X. | 登録日 | 2020-06-02 | 公開日 | 2021-07-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia. Nat Cancer, 2, 2021
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4V40
| BETA-GALACTOSIDASE | 分子名称: | BETA-GALACTOSIDASE, MAGNESIUM ION | 著者 | Jacobson, R.H, Zhang, X, Dubose, R.F, Matthews, B.W. | 登録日 | 1994-07-18 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Three-dimensional structure of beta-galactosidase from E. coli. Nature, 369, 1994
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6LA3
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6LAO
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6LBO
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6LBQ
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6LA4
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5HXD
| Crystal structure of murein-tripeptide amidase MpaA from Escherichia coli O157 | 分子名称: | CACODYLATE ION, Protein MpaA, ZINC ION | 著者 | Ma, Y, Bai, G, Zhang, X, Zhao, J, Yuan, Z, Kang, X, Li, Z, Mu, S, Liu, X. | 登録日 | 2016-01-30 | 公開日 | 2017-02-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure of Murein-Tripeptide Amidase MpaA from Escherichia coli O157 at 2.6 angstrom Resolution Protein Pept.Lett., 24, 2017
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4M5E
| Tse3 structure | 分子名称: | CADMIUM ION, CALCIUM ION, GLYCEROL, ... | 著者 | Qian, Y. | 登録日 | 2013-08-08 | 公開日 | 2014-04-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Structural insights into the T6SS effector protein Tse3 and the Tse3-Tsi3 complex from Pseudomonas aeruginosa reveal a calcium-dependent membrane-binding mechanism Mol.Microbiol., 92, 2014
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