7ZTM
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![BU of 7ztm by Molmil](/molmil-images/mine/7ztm) | Crystal Structure of Unlinked NS2B-NS3 Protease from Zika Virus in Complex with Inhibitor MI-2128 | 分子名称: | 1-[(5R,8R,15S,18S)-15-(4-azanylbutyl)-5-(cyclohexylmethyl)-18-(naphthalen-2-ylmethyl)-4,7,14,17,20-pentakis(oxidanylidene)-3,6,13,16,19-pentazabicyclo[20.3.1]hexacosa-1(25),22(26),23-trien-8-yl]guanidine, Serine protease NS3, Serine protease subunit NS2B | 著者 | Huber, S, Steinmetzer, T. | 登録日 | 2022-05-10 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Synthesis and structural characterization of new macrocyclic inhibitors of the Zika virus NS2B-NS3 protease. Arch Pharm, 2024
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7ZUM
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![BU of 7zum by Molmil](/molmil-images/mine/7zum) | Crystal Structure of Unlinked NS2B-NS3 Protease from Zika Virus in Complex with Inhibitor MI-2130 | 分子名称: | 1-[(5R,8R,15S,18S)-15-(4-azanylbutyl)-5-(cyclohexylmethyl)-18-(1H-indol-3-ylmethyl)-4,7,14,17,20-pentakis(oxidanylidene)-3,6,13,16,19-pentazabicyclo[20.3.1]hexacosa-1(25),22(26),23-trien-8-yl]guanidine, Serine protease NS3, Serine protease subunit NS2B | 著者 | Huber, S, Steinmetzer, T. | 登録日 | 2022-05-12 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Synthesis and structural characterization of new macrocyclic inhibitors of the Zika virus NS2B-NS3 protease. Arch Pharm, 2024
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7ZV4
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![BU of 7zv4 by Molmil](/molmil-images/mine/7zv4) | Crystal Structure of Unlinked NS2B-NS3 Protease from Zika Virus in Complex with Inhibitor MI-2195 | 分子名称: | 1-[(5R,8R,15S,18S)-15-[[3-(aminomethyl)phenyl]methyl]-18-(4-azanylbutyl)-5-(cyclohexylmethyl)-4,7,14,17,20-pentakis(oxidanylidene)-3,6,13,16,19-pentazabicyclo[20.3.1]hexacosa-1(25),22(26),23-trien-8-yl]guanidine, Serine protease NS3, Serine protease subunit NS2B | 著者 | Huber, S, Steinmetzer, T. | 登録日 | 2022-05-13 | 公開日 | 2023-03-22 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Synthesis and structural characterization of new macrocyclic inhibitors of the Zika virus NS2B-NS3 protease. Arch Pharm, 2024
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3HE7
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![BU of 3he7 by Molmil](/molmil-images/mine/3he7) | |
3I3L
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![BU of 3i3l by Molmil](/molmil-images/mine/3i3l) | Crystal structure of CmlS, a flavin-dependent halogenase | 分子名称: | Alkylhalidase CmlS, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Podzelinska, K, Soares, A, Jia, Z, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2009-06-30 | 公開日 | 2010-03-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Chloramphenicol Biosynthesis: The Structure of CmlS, a Flavin-Dependent Halogenase Showing a Covalent Flavin-Aspartate Bond J.Mol.Biol., 397, 2010
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3HUJ
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7LJ1
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![BU of 7lj1 by Molmil](/molmil-images/mine/7lj1) | Human Prx1-Srx Decameric Complex | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Forshaw, T.E, Reisz, J.A, Nelson, K.J, Gumpena, R, Lawson, J.R, Jonsson, T, Wu, H, Clodfelter, J.E, Johnson, L, Furdui, C.M, Lowther, W.T. | 登録日 | 2021-01-28 | 公開日 | 2021-07-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | 主引用文献 | Specificity of Human Sulfiredoxin for Reductant and Peroxiredoxin Oligomeric State. Antioxidants (Basel), 10, 2021
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7LII
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![BU of 7lii by Molmil](/molmil-images/mine/7lii) | Thermotoga maritima Encapsulin Nanocompartment Pore Mutant S7D | 分子名称: | Maritimacin, RIBOFLAVIN | 著者 | Andreas, M.P, Adamson, L, Tasneem, N, Close, W, Giessen, T, Lau, Y.H. | 登録日 | 2021-01-27 | 公開日 | 2022-02-09 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | 主引用文献 | Pore structure controls stability and molecular flux in engineered protein cages. Sci Adv, 8, 2022
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7LIL
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![BU of 7lil by Molmil](/molmil-images/mine/7lil) | Thermotoga maritima Encapsulin Nanocompartment Pore Mutant SE3 | 分子名称: | Maritimacin, RIBOFLAVIN | 著者 | Andreas, M.P, Adamson, L, Tasneem, N, Close, W, Giessen, T, Lau, Y.H. | 登録日 | 2021-01-27 | 公開日 | 2022-02-09 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Pore structure controls stability and molecular flux in engineered protein cages. Sci Adv, 8, 2022
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7LIM
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![BU of 7lim by Molmil](/molmil-images/mine/7lim) | Thermotoga maritima Encapsulin Nanocompartment Pore Mutant S6E | 分子名称: | Maritimacin, RIBOFLAVIN | 著者 | Andreas, M.P, Adamson, L, Tasneem, N, Close, W, Giessen, T, Lau, Y.H. | 登録日 | 2021-01-27 | 公開日 | 2022-02-09 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Pore structure controls stability and molecular flux in engineered protein cages. Sci Adv, 8, 2022
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7LIJ
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![BU of 7lij by Molmil](/molmil-images/mine/7lij) | Thermotoga maritima Encapsulin Nanocompartment Pore Mutant S1K | 分子名称: | Maritimacin, RIBOFLAVIN | 著者 | Andreas, M.P, Adamson, L, Tasneem, N, Close, W, Giessen, T, Lau, Y.H. | 登録日 | 2021-01-27 | 公開日 | 2022-02-09 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Pore structure controls stability and molecular flux in engineered protein cages. Sci Adv, 8, 2022
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7LIK
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![BU of 7lik by Molmil](/molmil-images/mine/7lik) | Thermotoga maritima Encapsulin Nanocompartment Pore Mutant S1R | 分子名称: | Maritimacin, RIBOFLAVIN | 著者 | Andreas, M.P, Adamson, L, Tasneem, N, Close, W, Giessen, T, Lau, Y.H. | 登録日 | 2021-01-27 | 公開日 | 2022-02-09 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | 主引用文献 | Pore structure controls stability and molecular flux in engineered protein cages. Sci Adv, 8, 2022
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7LIS
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![BU of 7lis by Molmil](/molmil-images/mine/7lis) | Thermotoga maritima Encapsulin Nanocompartment Pore Mutant S5D | 分子名称: | Maritimacin, RIBOFLAVIN | 著者 | Andreas, M.P, Adamson, L, Tasneem, N, Close, W, Giessen, T, Lau, Y.H. | 登録日 | 2021-01-27 | 公開日 | 2022-02-09 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | Pore structure controls stability and molecular flux in engineered protein cages. Sci Adv, 8, 2022
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7LIT
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![BU of 7lit by Molmil](/molmil-images/mine/7lit) | Thermotoga maritima Encapsulin Nanocompartment Pore Mutant S7G | 分子名称: | Maritimacin, RIBOFLAVIN | 著者 | Andreas, M.P, Adamson, L, Tasneem, N, Close, W, Giessen, T, Lau, Y.H. | 登録日 | 2021-01-27 | 公開日 | 2022-02-09 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | 主引用文献 | Pore structure controls stability and molecular flux in engineered protein cages. Sci Adv, 8, 2022
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7MHC
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![BU of 7mhc by Molmil](/molmil-images/mine/7mhc) | Structure of human STING in complex with MK-1454 | 分子名称: | (2R,5R,7R,8S,10R,12aR,14R,15S,15aR,16R)-7-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-14-(6-amino-9H-purin-9-yl)-15,16-difluoro-2,10-bis(sulfanyl)octahydro-2H,10H,12H-5,8-methano-2lambda~5~,10lambda~5~-furo[3,2-l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine-2,10-dione, Stimulator of interferon genes protein | 著者 | Lesburg, C.A. | 登録日 | 2021-04-15 | 公開日 | 2022-04-06 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | A kinase-cGAS cascade to synthesize a therapeutic STING activator. Nature, 603, 2022
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7NPD
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![BU of 7npd by Molmil](/molmil-images/mine/7npd) | Vibiro cholerae ParA2 | 分子名称: | Walker A-type ATPase | 著者 | Parker, A.V, Bergeron, J.R.C. | 登録日 | 2021-02-26 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The structure of the bacterial DNA segregation ATPase filament reveals the conformational plasticity of ParA upon DNA binding. Nat Commun, 12, 2021
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7N5S
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![BU of 7n5s by Molmil](/molmil-images/mine/7n5s) | ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 6) | 分子名称: | DNA Strand I, DNA Strand II, ZINC ION, ... | 著者 | Horton, J.R, Ren, R, Cheng, X. | 登録日 | 2021-06-06 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | 主引用文献 | Structural basis for human ZBTB7A action at the fetal globin promoter. Cell Rep, 36, 2021
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7N5T
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![BU of 7n5t by Molmil](/molmil-images/mine/7n5t) | ZBTB7A Zinc Finger Domain Bound to -200 Site of Fetal Globin Promoter (Oligo 5) | 分子名称: | DNA Strand I, DNA Strand II, ZINC ION, ... | 著者 | Horton, J.R, Ren, R, Cheng, X. | 登録日 | 2021-06-06 | 公開日 | 2021-08-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for human ZBTB7A action at the fetal globin promoter. Cell Rep, 36, 2021
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7NPF
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![BU of 7npf by Molmil](/molmil-images/mine/7npf) | Vibrio cholerae ParA2-ATPyS-DNA filament | 分子名称: | AAA family ATPase, DNA (49-MER), MAGNESIUM ION, ... | 著者 | Parker, A.V, Bergeron, J.R.C. | 登録日 | 2021-02-26 | 公開日 | 2021-10-06 | 最終更新日 | 2021-10-20 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | The structure of the bacterial DNA segregation ATPase filament reveals the conformational plasticity of ParA upon DNA binding. Nat Commun, 12, 2021
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7NLV
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![BU of 7nlv by Molmil](/molmil-images/mine/7nlv) | WILDTYPE CORE-STREPTAVIDIN WITH a conjugated BIOTINYLATED PYRROLIDINE II | 分子名称: | 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-((S)-pyrrolidin-3-yl)pentanamide, Streptavidin | 著者 | Nodling, A.R, Santi, N, Tsai, Y.H, Rizkallah, P, Luk, L.Y.P, Jin, Y. | 登録日 | 2021-02-22 | 公開日 | 2022-03-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | The role of streptavidin and its variants in catalysis by biotinylated secondary amines. Org.Biomol.Chem., 19, 2021
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7NPE
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![BU of 7npe by Molmil](/molmil-images/mine/7npe) | Vibrio cholerae ParA2-ADP | 分子名称: | AAA family ATPase, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | 著者 | Parker, A.V, Bergeron, J.R.C. | 登録日 | 2021-02-26 | 公開日 | 2021-07-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The cryo-EM structure of the bacterial type I segregation filament reveals ParA s conformational plasticity upon DNA binding To Be Published
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7N6E
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![BU of 7n6e by Molmil](/molmil-images/mine/7n6e) | TCR peptide HLA-A2 complex | 分子名称: | Beta-2-microglobulin, MHC class I antigen, Spike protein S1, ... | 著者 | Chaurasia, P, Rossjohn, J, Petersen, J. | 登録日 | 2021-06-08 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein. J.Biol.Chem., 297, 2021
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7N6D
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![BU of 7n6d by Molmil](/molmil-images/mine/7n6d) | HLA peptide complex | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, MHC class I antigen, ... | 著者 | Chaurasia, P, Petersen, J, Rossjohn, J. | 登録日 | 2021-06-08 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis of biased T cell receptor recognition of an immunodominant HLA-A2 epitope of the SARS-CoV-2 spike protein. J.Biol.Chem., 297, 2021
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7MU9
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4JQX
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![BU of 4jqx by Molmil](/molmil-images/mine/4jqx) | HLA-B*44:03 in complex with Epstein-Barr virus BZLF1-derived peptide (residues 169-180) | 分子名称: | ACETATE ION, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Theodossis, A, Welland, A, Gras, S, Rossjohn, J. | 登録日 | 2013-03-20 | 公開日 | 2013-06-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | HLA Peptide Length Preferences Control CD8+ T Cell Responses. J.Immunol., 191, 2013
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