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6E5U
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BU of 6e5u by Molmil
Crystal structure of the mRNA export receptor NXF1/NXT1 in complex with influenza virus NS1 protein
分子名称: NTF2-related export protein 1, Non-structural protein 1, Nuclear RNA export factor 1
著者Xie, Y, Ren, Y.
登録日2018-07-23
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural basis for influenza virus NS1 protein block of mRNA nuclear export.
Nat Microbiol, 4, 2019
5IIB
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BU of 5iib by Molmil
Crystal structure of red abalone egg VERL repeat 3 in complex with sperm lysin at 1.64 A resolution (crystal form II)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Egg-lysin, ...
著者Raj, I, Sadat Al-Hosseini, H, Nishimura, K, De Sanctis, D, Jovine, L.
登録日2016-03-01
公開日2017-06-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural Basis of Egg Coat-Sperm Recognition at Fertilization.
Cell, 169, 2017
5I04
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BU of 5i04 by Molmil
Crystal structure of the orphan region of human endoglin/CD105
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Maltose-binding periplasmic protein,Endoglin, TRIETHYLENE GLYCOL, ...
著者Saito, T, Bokhove, M, de Sanctis, D, Jovine, L.
登録日2016-02-03
公開日2017-06-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural Basis of the Human Endoglin-BMP9 Interaction: Insights into BMP Signaling and HHT1.
Cell Rep, 19, 2017
5II7
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BU of 5ii7 by Molmil
In-house sulfur-SAD structure of orthorhombic red abalone lysin at 1.66 A resolution
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Egg-lysin, SULFATE ION
著者Sadat Al-Hosseini, H, Raj, I, Nishimura, K, Jovine, L.
登録日2016-03-01
公開日2017-06-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structural Basis of Egg Coat-Sperm Recognition at Fertilization.
Cell, 169, 2017
5II9
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BU of 5ii9 by Molmil
Monoclinic crystal structure of red abalone lysin at 2.11 A resolution
分子名称: Egg-lysin
著者Sadat Al-Hosseini, H, Raj, I, Nishimura, K, Jovine, L.
登録日2016-03-01
公開日2017-06-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural Basis of Egg Coat-Sperm Recognition at Fertilization.
Cell, 169, 2017
5II8
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BU of 5ii8 by Molmil
Orthorhombic crystal structure of red abalone lysin at 0.99 A resolution
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Egg-lysin, SULFATE ION
著者Sadat Al-Hosseini, H, Raj, I, Nishimura, K, De Sanctis, D, Jovine, L.
登録日2016-03-01
公開日2017-06-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (0.99 Å)
主引用文献Structural Basis of Egg Coat-Sperm Recognition at Fertilization.
Cell, 169, 2017
5YMV
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BU of 5ymv by Molmil
Crystal structure of 9-mer peptide from influenza virus in complex with BF2*1201
分子名称: ALA-VAL-LYS-GLY-VAL-GLY-THR-MET-VAL, Beta-2-microglobulin, Class I histocompatibility antigen, ...
著者Xiao, J, Xiang, W, Qi, J, Chai, Y, Liu, W.J, Gao, G.F.
登録日2017-10-22
公開日2018-10-24
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (2.197 Å)
主引用文献An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I.
J Immunol., 201, 2018
5YMW
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BU of 5ymw by Molmil
Crystal structure of 8-mer peptide from Rous sarcoma virus in complex with BF2*1201
分子名称: Beta-2-microglobulin, Class I histocompatibility antigen, F10 alpha chain, ...
著者Xiao, J, Xiang, W, Qi, J, Chai, Y, Liu, W.J, Gao, G.F.
登録日2017-10-22
公開日2018-10-24
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I.
J Immunol., 201, 2018
7WL2
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BU of 7wl2 by Molmil
Mouse Pendrin in bicarbonate and iodide buffer in inward state
分子名称: Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-12
公開日2023-04-12
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WL9
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BU of 7wl9 by Molmil
Mouse Pendrin in chloride and bicarbonate in asymmetric state
分子名称: CHLORIDE ION, Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-12
公開日2023-04-12
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WLE
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BU of 7wle by Molmil
Mouse Pendrin in chloride and bicarbonate buffer in outward state
分子名称: Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-13
公開日2023-04-12
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WLA
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BU of 7wla by Molmil
Mouse Pendrin in bicarbonate and iodide buffer in asymmetric state
分子名称: Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-12
公開日2023-04-12
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WK1
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BU of 7wk1 by Molmil
Mouse Pendrin bound chloride in inward state
分子名称: CHLORIDE ION, Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-08
公開日2023-04-12
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WL7
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BU of 7wl7 by Molmil
Mouse Pendrin in chloride and bicarbonate buffer in inward state
分子名称: Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-12
公開日2023-04-12
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WK7
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BU of 7wk7 by Molmil
Mouse Pendrin bound bicarbonate in inward state
分子名称: BICARBONATE ION, Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-08
公開日2023-05-17
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WL8
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BU of 7wl8 by Molmil
Mouse Pendrin in chloride and iodide buffer in inward state
分子名称: Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-12
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
7WLB
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BU of 7wlb by Molmil
Mouse Pendrin in chloride and iodide buffer in asymmetric state
分子名称: Pendrin
著者Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G.
登録日2022-01-12
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
8TYN
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BU of 8tyn by Molmil
Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state (tetramer model)
分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
登録日2023-08-25
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 2024
9C0Y
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BU of 9c0y by Molmil
Clathrin terminal domain complexed with Pitstop 2c
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Clathrin heavy chain 1, ...
著者Bulut, H, Horatscheck, A, Krauss, M, Santos, K.F, McCluskey, A, Wahl, C.W, Nazare, M, Haucke, V.
登録日2024-05-28
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Acute inhibition of clathrin-mediated endocytosis by next-generation small molecule inhibitors of clathrin function
To Be Published
9C0Z
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BU of 9c0z by Molmil
Clathrin terminal domain complexed with pitstop 2d
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ...
著者Bulut, H, Horatscheck, A, Krauss, M, Santos, K.F, McCluskey, A, Wahl, C.W, Nazare, M, Haucke, V.
登録日2024-05-28
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Acute inhibition of clathrin-mediated endocytosis by next-generation small molecule inhibitors of clathrin function
To Be Published
8TYM
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BU of 8tym by Molmil
Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state
分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E.
登録日2023-08-25
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
Dev.Cell, 2024
8VXE
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BU of 8vxe by Molmil
Structure of p38 alpha (Mitogen-activated protein kinase 14) complexed with inhibitor 6
分子名称: (4M)-4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine, Mitogen-activated protein kinase 14
著者Blaesse, M, Steinbacher, S, Shaffer, P.L, Sharma, S, Thompson, A.A.
登録日2024-02-04
公開日2024-05-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure-Based Optimization of Selective and Brain Penetrant CK1 delta Inhibitors for the Treatment of Circadian Disruptions.
Acs Med.Chem.Lett., 15, 2024
8VXD
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BU of 8vxd by Molmil
Structure of Casein kinase I isoform delta (CK1d) complexed with inhibitor 7
分子名称: (4P)-4-[(3P)-3-(5-fluoropyridin-2-yl)-1-methyl-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine, Casein kinase I isoform delta
著者Thompson, A.A, Milligan, C.M, Sharma, S.
登録日2024-02-04
公開日2024-05-08
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Structure-Based Optimization of Selective and Brain Penetrant CK1 delta Inhibitors for the Treatment of Circadian Disruptions.
Acs Med.Chem.Lett., 15, 2024
8VXF
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BU of 8vxf by Molmil
Structure of Casein kinase I isoform delta (CK1d) complexed with inhibitor 15
分子名称: (2P,3P,8S)-2-(5-fluoropyridin-2-yl)-6,6-dimethyl-3-(1H-pyrazolo[3,4-b]pyridin-4-yl)-6,7-dihydro-4H-pyrazolo[5,1-c][1,4]oxazine, Casein kinase I isoform delta
著者Thompson, A.A, Milligan, C.M, Sharma, S.
登録日2024-02-04
公開日2024-05-08
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structure-Based Optimization of Selective and Brain Penetrant CK1 delta Inhibitors for the Treatment of Circadian Disruptions.
Acs Med.Chem.Lett., 15, 2024
8V4F
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BU of 8v4f by Molmil
Model and map from local refinement of a CAB-A17 - Omicron Ba.1 spike complex
分子名称: CAB-A17 variable heavy-chain, CAB-A17 variable light chain, Spike protein S1
著者Hallberg, B.M, Das, H.
登録日2023-11-29
公開日2024-06-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies.
Cell Rep Med, 5, 2024

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件を2024-07-17に公開中

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